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Dr. GPCR Podcast - The Voice of the Community Whether you’re a scientist, student, or just curious, you’ll hear about discoveries, career stories, and the latest GPCR news. Jump in and get inspired! Strategic Partners Latest Podcast Episodes 2026-02-18 2025-12-03 2025-10-22 2025-08-19 2025-07-08 2025-05-13 2026-02-04 2025-11-19 2025-09-22 2025-08-05 2025-06-11 2025-04-29 2025-12-17 2025-11-05 2025-09-02 2025-07-22 2025-05-27 1 2 3 4 5 1 ... 1 2 3 4 5 6 7 8 ... 8 Enjoying the Dr. GPCR Podcast? Leave a Review. Leave a quick review to help more scientists find the show—and help us keep improving every episode. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Thanks for listening to this podcast episode Follow us on your favorite Podcast Player Listen and subscribe where you get your podcasts

Stay at the Forefront of GPCR Drug Discovery Gain insider methods from the pioneers shaping biased signaling, assay design, and pharmacology—skills you won't find in any textbook or paper. ⧖ Hours of Expert Training ↓ Downloadable Resources ◕ New Courses added regularly + All included in Premium Go Premium! Explore the Masterclasses Full classes require Premium. Filter by Category Filter by Level Filter by Instructor Watch Now Terry Kenakin Decoding Drug Action Watch Now Terry Kenakin Seeing is Believing: Assaying Drug Action Coming Soon Terry Kenakin The Allosteric Advantage Watch Now Sam Hoare CRC Super-User: Your Data Advantage Watch Now Terry Kenakin The Art of Antagonism Coming Soon Sam Hoare The Agonist Effect: A Story of Bias Watch Now Terry Kenakin Unlocking Agonist Behavior Coming Soon Sam Hoare The Antagonist's Grip Coming Soon Sam Hoare The Dynamic Allosteric Effect 1 2 1 ... 1 2 ... 2 Learn directly from world leaders in GPCR research Access exclusive training from the scientists shaping the future of GPCR drug discovery Dr. Sam Hoare Pharmechanics GPCR signaling & biased agonism expert regularly consulted by top pharma companies for assay design strategies. Pioneer in quantitative pharmacology methods. Dr. Yamina Berchiche Dr. GPCR & Yamina's Corner Community builder for scientists with expertise in GPCR project strategy and translational applications. Dr. Terry Kenakin Terry's Corner Author of 'A Pharmacology Primer', the definitive GPCR reference used by labs worldwide. Former GSK principal research investigator with 40+ years of experience. Unlock All GPCR Masterclasses 🔥 Upgrade to Premium Premium Yearly $499 $ 499 Every year 🚀 Everything you need to master GPCR science — in one membership. Valid until canceled Join Premium Now 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research, careers & event intelligence 🤝 Members-only networking, AMAs & matchmaking 💡 Support open resources for the global GPCR field 🧠 Designed for researchers at every career stage 🚀 Don’t just keep up — lead the way. 🔒 Grandfather Guarantee, your rate never increases What others are saying Dr. Hoare is very experienced in the field. What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended. The really unexpected was that the Q&A sessions reached the highest level—beyond excellent. I am a convert! I will keep Dr. GPCR and the offered resources in my work sphere Anonymous Thank you for bringing this course with Dr. Kenakin. I wish Dr. GPCR the best for the sake of promoting more educational opportunities that are sorely needed in the field Anonymous The content had enough depth to satisfy the hunger for theory while being full of practical knowledge Anonymous The best pharmacology teacher teaming up with the best GPCR community platform to help train and inspire the next generation of scientists. Also super-valuable for those of us learning how to teach pharmacology Anonymous Dr. Hoare's extensive and elaborative explanation of the topics at hand was excellent and very digestible. Thoroughly enjoyed learning from him Anonymous Dr. Kenakin is a leading expert in the field. Aside from his vast experience in drug development, not to mention his extensive publication record, Dr. Kenakin is a masterful teacher and communicator. Anonymous Frequently Asked Questions What is a GPCR Masterclass? A deep-dive training session led by top GPCR scientists, covering pharmacology, signaling, assays, and drug discovery. Each masterclass focuses on practical methods you can apply immediately to your research. Who should join? PhD students, postdocs, biotech/industry scientists, and anyone working with GPCRs who wants to accelerate their research and avoid common pitfalls that waste time and resources. How do I access the masterclasses? Premium members get unlimited, on-demand access to all masterclasses. Watch on any device, anytime. All content is available immediately after joining. Can I preview before joining? Yes – every course includes a free trailer that gives you a taste of the content and teaching style. How do I fit this in my schedule? Each masterclass is designed as a focused 60-90 minute session that you can watch in one sitting or break into smaller segments. Many members watch during lunch breaks or dedicate one evening per week to professional development. What makes your courses different from reading books or articles on PubMed? Our courses offer direct methods, shortcuts, and case studies from experts that you won't find in books or articles on PubMed. We reveal the practical 'how' behind successful experiments, saving you months of trial and error. The GPCR Field Is Advancing Fast – Don't Fall Behind Stay ahead in drug discovery with insights from the world's top GPCR experts. Get Access Today!

Advanced GPCR webinars for pharmacologists and biotech scientists. Live Q&A. Deep mechanistic insight. Reserve your seat. Live GPCR Webinars with the World’s Leading Experts. Learn Faster. Ask Directly. Stay Ahead. Deep-dive sessions focused on real pharmacology, real drug discovery challenges, and real translational insight. * Created by scientists, for scientists 👉 Save Your Spot Strategic Partners The Dr. GPCR Webinar Series was created to accelerate GPCR research by connecting scientists directly with leaders in pharmacology, structural biology, drug discovery, and translational science. What makes these webinars different? 🧠 Deep Mechanistic Focus Not “overview talks.” Real models, real data, real debate. 🔬 Drug Discovery Relevance From receptor theory to clinical translation. 🎙️ Direct Access to Experts Live Q&A. Ask what you actually struggle with. 🌍 Global GPCR Community Engage with peers across academia and industry. Free GPCR Webinars Fluorescent Probes for GLP-1R and GIPR Imaging: From Cell Assays to In Vivo Systems Speakers Dr. Johannes Broichhagen - Junior Group Leader Dr. David Hodson Learning Outcome: Understand the design and selectivity of LUXendin and daLUXendin probes for GLP-1R and GIPR labeling Apply these probes across imaging workflows from live cells to in vivo systems Choose the right probe for your experimental context Handle, reconstitute, and store fluorescent probes correctly for consistent results Interpret receptor localization and nanodomain data in complex biological systems March 3, 2026 at 3:00:00 PM 📆 Reserve Your Spot Details 1 1 ... 1 ... 1 Frequently asked questions What are GPCR webinars? GPCR webinars are live online scientific sessions focused on G protein-coupled receptor (GPCR) biology, pharmacology, signaling, and drug discovery. Each session explores mechanistic models, translational challenges, and real-world therapeutic implications. These webinars are designed for scientists who want deep, data-driven discussion rather than surface-level overviews. Who should attend these GPCR pharmacology webinars? These webinars are ideal for: • GPCR pharmacologists • Medicinal chemists working on receptor targets • Structural biologists • Translational scientists • Biotech and pharmaceutical researchers • Postdoctoral fellows and graduate researchers entering drug discovery If you work directly with receptor systems, ligand design, efficacy modeling, or signaling pathways, these sessions are built for you. Are these GPCR webinars suitable for industry scientists? Yes. The content is highly relevant for biotech and pharmaceutical scientists. Topics frequently address: • Receptor efficacy and bias • Allosteric modulation • PK/PD relationships • Irreversible binding and safety considerations • Translational pharmacology challenges The discussions are grounded in practical drug discovery, not just academic theory. How are these different from academic seminars or conferences? Most academic seminars focus on a single dataset or publication. These GPCR webinars focus on conceptual frameworks, models, and translational insight that apply across programs. Unlike large conferences, the live format allows direct interaction, questions, and scientific debate in real time. The goal is not presentation — it is scientific advancement. Are the webinars live or pre-recorded? The sessions are delivered live to allow direct Q&A with the speaker. Live participation gives you the opportunity to ask technical questions and engage in discussion with other scientists in the GPCR community. Selected recordings may be available afterward through the Dr. GPCR platform. Do I need prior knowledge of GPCR pharmacology? These webinars are designed for scientists with foundational knowledge in receptor pharmacology, signaling, or drug discovery. While some sessions may introduce key concepts, the overall level is advanced and assumes familiarity with pharmacological models and terminology. What topics are typically covered in GPCR webinars? Topics may include: • Receptor efficacy and operational models • Allosteric modulators (PAMs and NAMs) • Biased agonism • Dose–response modeling • Calcium and signaling assays • Drug–receptor kinetics • Translational pharmacology strategies • GPCR structure–function relationships Each session focuses on mechanistic clarity and practical application. Are these GPCR webinars free? Yes. All live GPCR webinars are free to attend. To receive early notifications, event reminders, and priority updates, you can join the Dr. GPCR Ecosystem as a free member. If you would like to go deeper beyond the live sessions, you can explore the full GPCR educational library inside Dr. GPCR University.(https://www.ecosystem.drgpcr.com/gpcr-university) Will attending help with continuing education or professional development? Yes. These webinars are designed to support ongoing scientific development in GPCR pharmacology and drug discovery. They provide exposure to current thinking, advanced modeling approaches, and expert interpretation of complex receptor behavior. For researchers working in biotech, pharma, or academia, this type of continuing education can strengthen both technical expertise and strategic thinking. How often are new GPCR webinars added? New live GPCR webinars are added regularly as part of the Dr. GPCR Ecosystem’s ongoing educational initiative. Upcoming sessions are announced in advance and updated on this page. Where can I find advanced GPCR training online? Dr. GPCR provides live GPCR webinars, masterclasses, and in-depth educational resources focused specifically on receptor pharmacology and drug discovery. These programs are designed for scientists seeking advanced, mechanism-focused training in GPCR biology. These sessions are part of a larger mission: building the most trusted home for GPCR scientists worldwide. Join the Next Live Session Be in the room when the science moves forward. 👉 Reserve Your Spot Now

< Back to Webinars Fluorescent Probes for GLP-1R and GIPR Imaging: From Cell Assays to In Vivo Systems Fluorescent tools for imaging endogenous incretin receptors across biological systems 📅 March 3, 2026 at 3:00:00 PM 🤝 Dr. GPCR x Celtarys Reserve Your Seat! Interrogating Incretin Receptor Biology Across Biological Complexity GLP-1 and GIP receptors have emerged as central targets in metabolic medicine, yet their precise localization, nanodomain organization, and functional engagement within complex biological systems remain incompletely understood. Fluorescent chemical probes offer one of the most direct approaches for investigating receptor distribution and dynamics in native contexts — without relying on receptor overexpression or genetic modification. This webinar introduces two families of advanced fluorescent probes developed specifically for working with endogenous GLP-1R and GIPR across a range of biological complexity. Attendees will gain a technical understanding of probe design, selectivity, and validated applications — as well as practical guidance on handling, reconstitution, dilution, and storage to support immediate laboratory deployment. LUXendin Family Red and far-red fluorescent GLP-1R antagonists derived from Exendin4(9–39). Enable high-specificity labeling of endogenous GLP-1R in live and fixed cells, pancreatic islets, and whole-organ preparations — without triggering receptor activation. Available across multiple spectral ranges for confocal, super-resolution, and intravital imaging. daLUXendin Family Fluorescent dual agonists for both GLP-1R and GIPR (daLUXendin544+ and daLUXendin660+), structurally related to tirzepatide. Enable simultaneous visualization of endogenous receptor localization and nanodomain organization in pancreatic islet cells and neural sites of action in vivo. Speaker Introductions Dr. Johannes Broichhagen Group Leader Leibniz Research Institute for Molecular Pharmacology (FMP), Berlin Dr. Broichhagen trained in chemistry at the University of Erlangen-Nuremberg, completed his doctorate at LMU Munich in 2014, and undertook postdoctoral work at EPFL (Switzerland) and the Max Planck Institute for Medical Research (Heidelberg). Since 2020, he leads an independent research group at the FMP Berlin. His group focuses on the development of chemical tools — including fluorescent ligands and photopharmacological compounds — to investigate GPCR biology with spatial and temporal precision. He is a principal architect of the LUXendin and daLUXendin probe families. Dr. David Hodson Robert Turner Professor of Diabetic Medicine Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford Dr. Hodson is a veterinary surgeon by training who pursued postdoctoral studies at the CNRS in Montpellier before establishing his independent laboratory at Imperial College London as a Diabetes UK RD Lawrence Fellow. He previously served as Professor of Cellular Metabolism and Institute Deputy Director at the University of Birmingham. His research group develops and applies novel technologies to investigate GLP-1 and GIP receptors — two class B GPCRs central to glucose homeostasis, food intake regulation, and inflammation — within complex tissue environments including the pancreas and brain. His work carries direct translational relevance to diabetes and obesity therapeutics. About the Organizers Celtarys Research Celtarys develops and commercializes fluorescent chemical tools and related screening services that enable fluorescence-based methods across drug discovery. The company's portfolio is built around high-affinity, selective fluorescent ligands for GPCRs, supporting researchers working at the interface of chemical biology and pharmacology. Broad GPCR fluorescent ligand portfolio across multiple receptor families Fluorescence Polarization, HTRF, and High-Content Screening formats Fluorescence microscopy and flow cytometry applications Screening services using proprietary probes in living cells Custom chemical development for probe and ligand creation Dr. GPCR Dr. GPCR is a membership-based nonprofit ecosystem dedicated to advancing GPCR-targeted drug discovery. It provides curated industry intelligence, expert-led masterclasses, and structured engagement opportunities for scientists and biotech leaders working across pharmacology, translational research, and therapeutic development. Curated intelligence on GPCR drug discovery trends and developments Expert-led webinars and masterclasses with leading researchers Structured networking for scientists and biotech professionals Nonprofit model — community-first, member-driven Free membership tier available Previous Webinar Next Webinar Don’t Miss the Next Live Session Dr. GPCR membership gives you access to all upcoming live, interactive webinars. Free. Takes less than a minute to join. Cancel anytime. Sign Up for Free

Discover the Dr. GPCR Ecosystem – the ultimate hub for GPCR professionals to connect, collaborate, and advance drug discovery. Home: About Accelerating GPCR Drug Discovery, Together Dr. GPCR is the global hub where academia and industry meet to advance GPCR research, accelerate drug discovery, and foster collaboration across the entire ecosystem. 👉 Join Free Today 🔒 Go Premium Strategic Partner(s) Your Path to GPCR Mastery Flexible, career-ready courses designed by scientists for scientists. 🔒 GPCR Masterclass ➚ 🔒 Terry's Corner ➚ 🔒 GPCR Weekly News ➚ Dr. GPCR Podcast ➚ Articles from the Ecosystem ➚ First AMA of 2026: GPCR Pharmacology, Biased Signaling & Mechanistic Clarity The Real Cost of Strategic Overload in Biotech C5aR Fluorescent Ligands: Need for new Research Tools Integrated GPCR Drug Discovery: A Structured Framework for Modern Programs Closing the Gap Between Academia and Industry Our vision is simple: empower the GPCR field through shared knowledge, collaboration, and open access to tools that accelerate drug discovery. 🤝 Support the Mission Home: Premium Premium Yearly $499 $ 499 Every year 🚀 Everything you need to master GPCR science — in one membership. Valid until canceled Select 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research, careers & event intelligence 🤝 Members-only networking, AMAs & matchmaking 💡 Support open resources for the global GPCR field 🧠 Designed for researchers at every career stage 🚀 Don’t just keep up — lead the way. 🔒 Grandfather Guarantee, your rate never increases Everything You Need to Master GPCR Science in One Membership Join the most complete GPCR learning & collaboration hub. Explore the packages and choose one that works for you Advancing GPCR Science Through Collective Intelligence Dr. GPCR is a living ecosystem where global minds converge to share knowledge, spark collaboration, and shape the future of GPCR-driven discovery. 🤝 Support the Mission

Your go-to hub for everything GPCR! Stay ahead with the latest research breakthroughs, industry updates, job opportunities, and upcoming events—all in one place. GPCR Weekly News - Your Hub for GPCR Research, Industry Updates, Jobs & Events Delivered straight to your inbox every week Become a Premium Member Welcome to GPCR Weekly News! Whether you're a GPCR scientist, biotech innovator, or industry professional, GPCR Weekly News keeps you connected to the discoveries and opportunities that matter most. Latest Research Breakthrough discoveries, new publications, and cutting-edge GPCR research insights. Industry Events Upcoming conferences, workshops, webinars, and networking events worldwide. Career Opportunities GPCR job listings, career tips, and networking opportunities in the field. Read the Free Edition Here's a preview of what you'll find in our latest newsletter Integrated GPCR Drug Discovery: A Structured Framework for Modern Programs Integrated GPCR drug discovery demands more than isolated experiments. It requires alignment across chemistry, modeling, pharmacology, and translational strategy. This week, we introduce the newly structured Dr. GPCR University — ten reformatted masterclasses now fully integrated into Premium — and what that means for discovery teams. Dr. GPCR News 3 min read Get Premium for Full Access Latest Issues From Ligand Design to Disease Models — An Integrated GPCR Framework Read Full Issue February 13 - 19, 2026 Sharpening GPCR Drug Discovery Decisions Read Full Issue February 6 - 12, 2026 A New Era for the Dr. GPCR Ecosystem—Built for What Comes Next Read Full Issue December 19 - February 5, 2026 Binding Affinity, Measured With Confidence — Closing Out 2025 Read Full Issue December 12 - 18, 2025 2025 Wrap-Up : A Year of Progress Across the GPCR Community Read Full Issue December 5 - 11, 2025 How System-Level GPCR Insights Strengthen Every Discovery Decision Read Full Issue November 21 - December 4, 2025 1 2 3 4 5 1 ... 1 2 3 4 5 6 7 8 9 ... 9 About GPCR Weekly News GPCR Weekly News was launched in 2020 as part of the Dr. GPCR initiative. Our mission is to provide timely, relevant, and accessible information to scientists and industry professionals working in GPCR research and drug discovery. Every week, our team curates the most important developments so you never miss a breakthrough, opportunity, or event that could impact your work. Learn More about DrGPCR Unlock Premium 🔥 Upgrade to Premium Premium Yearly $499 $ 499 Every year 🚀 Everything you need to master GPCR science — in one membership. Valid until canceled Join Premium Now 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research, careers & event intelligence 🤝 Members-only networking, AMAs & matchmaking 💡 Support open resources for the global GPCR field 🧠 Designed for researchers at every career stage 🚀 Don’t just keep up — lead the way. 🔒 Grandfather Guarantee, your rate never increases Ready to Stay Ahead in GPCR Research? Join scientists worldwide who rely on GPCR Weekly News for the latest insights and opportunities.

Home Registration Full Agenda Venue Travel Tips Sponsors Special Issue on Adhesion GPCRs CINVESTAV, Mexico City, Mexico October 23-25 Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE Oct 23 - 9:00 AM Registration & Coffee with light breakfast Read More 9:50 AM Welcoming Remarks Read More 10:00 AM Student Flash Presentations Health and Disease, Metabolism, Nervous System, Proteomics and Transcriptomics, Receptor Structure, Signaling and Activation Mechanism Abhishek Kumar Singh · Alex Torrelli-Diljohn · Emmanouil Kyrloglou · Vasiliki Karagiannakou · Lara-Sophie Brodmerkel · Rashed Rezwan Parag · Hailey Steichen · Tyler Bernadyn · Jesse Stillwell Read More 12:00 PM Coffee Break with lights snacks Read More 12:30 PM State of the Art Talk Adhesion GPCR in Mechanobiology Tobias Langenhan Read More 1:00 PM Plenary Lecture Identification and Functional Characterization of Adhesion GPCRs As Steroid Hormone Receptors and Hearing and Balance Receptors Jinpeng Sun Read More 2:00 PM Complimentary Lunch Read More 3:00 PM Session I Tethered agonist - dependent/independent activation mechanism in AGPCRs Signe Mathiasen · Demet Araç · Andrew Dates · Frank Kwarcinski · Peng Xiao Read More 4:30 PM Leaving for City Center Read More 5:00 PM Mexico City Nocturnal Tour, Food and drinks Read More Oct 24 - 9:00 AM Session II AGPCR signaling pathways and trafficking Yuling Feng · Monserrat Avila Zozaya · Erwin G. Van Meir · Pal Kasturi Read More 10:30 AM Coffee Break with lights snacks Read More 11:00 AM Session III Molecular tools and biosensors directed at AGPCR signaling and function Stephanie Häfner · Laurent Sabbagh · Ana Lilia Moreno Salinas Read More 12:00 PM Session IV AGPCRs signaling in the nervous system Joseph Duman · Simeon R. Mihaylov · Anne Bormann Read More 1:00 PM Complimentary Lunch Read More 2:00 PM Posters Caroline Formstone · Jianxiang Xue · Virginea de Araujo Farias · Szymon P. Kordon · Tingzhen Shen · Bill Huang · Júlia Rosell · Sheila Ribalta-Mena · Mariam Melkumyan Read More 3:00 PM Session V Structural mechanisms of AGPCR signaling and function Fabian Pohl · Sumit Bandekar · Florian Seufert Read More 4:00 PM Board meeting/General assembly Welcome to Join Read More 5:00 PM Leave for dinner reception Read More 5:30 PM Complimentary Reception dinner Read More Oct 25 - 9:00 AM Session VI AGPCRs shaping the nervous system Yimin Zou · Dimitris Placantonakis · Nicole Perry-Hauser Read More 10:00 AM Coffee Break with lights snacks Read More 10:30 AM Session VII Physiological and pathological roles of AGPCRs in the nervous system Beatriz Blanco Redondo · Willem Berend Post Read More 11:10 AM Dr. GPCR Community Presentation Monserrat Avila Zozaya Read More 11:30 AM Session VIII Physiological and pathological roles of AGPCRs in the periphery Cheng-Chih Hsiao · Anastasia Georgiadi · Douglas Tilley Read More 12:30 PM Complimentary Lunch Read More 1:30 PM Session VIII * Physiological and pathological roles of AGPCRs in the periphery Tobias Langenhan · Anastasia Georgiadi · Douglas Tilley · Hee-Yong Kim · Alain Garcia De Las Bayonas · Gabriela Aust Read More 2:50 PM Session IX / Technology capsule: Light on aGPCR signaling and function NovoiSMART - A new platform for GPCR antibody drug discovery Gavin Zhang Read More 3:20 PM Coffee Break with pastries announcement of the aGEM award Read More 4:00 PM Closing remarks Read More Jinpeng Sun Identification and Functional Characterization of Adhesion GPCRs As Steroid Hormone Receptors and Hearing and Balance Receptors Bill Huang Self-Cleavage of GPR110 SEA Domain and Its Impact on GAIN Domain Autoproteolysis Andrew Dates Heterogeneity of Tethered Agonist Signaling in Adhesion G Protein-Coupled Receptors Pal Kasturi Site Specific N-Glycosylation Of The N-Terminal Fragment Of ADGRG6 Drives Proteolytic Processing, Trafficking And Signalling Ana Lilia Moreno Salinas Characterizing hADGRE5/CD97 Activation and Signaling: A Mechanical Stimulation BRET-Based Approach (MS-BRET) Florian Seufert Unveiling the GPS Cleavage Mechanism in ADGRL1 with QM/MM Willem Berend Post The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation Tobias Langenhan The CELSR/ADGRC Homolog Flamingo Is Not Autoproteolytically Processed By The GAIN Domain Rashed Rezwan Parag Novel isoforms of adhesion G protein coupled receptor B1 (ADGRB1/BAI1) generated from an alternative promoter in intron 17 Emmanouil Kyrloglou GPR124 Mediates Adhesion Of Leukemic Stem Cells To Their Niche And Leads To Myeloid Skewing Virginea de Araujo Farias Anti-Tumorigenic Role of Brain Angiogenesis Inhibitor 3 (BAI3) in WNT-Activated Medulloblastomas Szymon P. Kordon Conformational And Functional Coupling Between Extracellular and Transmembrane Regions of a Holo-Adhesion GPCR Frank Kwarcinski Discriminating between the extracellular scaffolding and G protein signaling roles of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse, H381S Erwin G. Van Meir Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, increase radiosensitivity and augment survival in medulloblastoma. Laurent Sabbagh bioSens-All: A Multiparametric BRET-Based Platform for Comprehensive Profiling of adhesion GPCR Signaling and Pharmacology-Enabling Drug Discovery Fabian Pohl Structural Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G Protein-Coupled Receptors Beatriz Blanco Redondo Uncovering the signaling pathway of the ADGRA homolog Remoulade in Drosophila Douglas Tilley ADGRF5-mediated regulation of cardiac health and disease Abhishek Kumar Singh Adgrg6/Gpr126 is Required for Myocardial Notch Activity and N-cadherin Localization to Attain Trabecular Identity Lara-Sophie Brodmerkel GAIN Domain Dynamics And Its Relevance For Adhesion GPCR Signaling In Vivo Caroline Formstone Interrogating The Role Of CELSR1 (ADGRC1) In Breast Cancer Mariam Melkumyan GPR110 modulates anxiety-like behaviors and memory function in mice potentially through neuronal and neuroimmune alterations during neurodevelopment Signe Mathiasen Signaling Properties of ADGRL3 Monserrat Avila Zozaya The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial cell identity and function Simeon R. Mihaylov Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase TNIK Sumit Bandekar Structural studies of the CELSR1 extracellular region reveal a compact multidomain module of fourteen domains which regulates signaling Nicole Perry-Hauser Adhesion G protein-coupled receptor latrophilin-3 (ADGRL3) modulation of dopaminergic neurotransmission Anastasia Georgiadi Adhesion GPCR GPR116/Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications for adaptive thermogenesis during prolonged cold exposure Jesse Stillwell Next Generation MBD2 inhibitors for Brain Cancer Therapy Hailey Steichen Identification of Differentially Expressed Gpr116 (Adgrf5) Transcript Variants in Mouse Kidney Sheila Ribalta-Mena Endocytic Cues Determine the Signaling Profile of Adhesion GPCR ADGRL1 / Latrophilin-1 Jianxiang Xue Generation and characterization of collecting duct specific GPR56 knockout mice Demet Araç An ECR-Mediated and TA-independent Mechanism of aGPCR Activation: Direct Communication of Extracellular Region with Transmembrane Domain in a Holo-Adhesion GPCR Yuling Feng Localization of putative ligands for adhesion G protein-coupled receptors in mouse tissues. Joseph Duman BAI1/ADGRB1-mediated Regulation of Mitochondrial Morphology in Axons Yimin Zou ADGRCs in glutamatergic synapse formation, maintenance and degeneration Cheng-Chih Hsiao ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Alain Garcia De Las Bayonas The Adhesion GPCR Cupidon Regulates Mating In The Closest Relatives Of Animals Alex Torrelli-Diljohn Investigating The Role of ADGRB3 Loss of Expression in Brain Tumor Formation in Li-Fraumeni Syndrome Tyler Bernadyn Elucidating The Role Of GPR97/ADGRG3 In Neutrophil Biology Tingzhen Shen Deorphanization Of The Adhesion GPCRs GPR110 and GPR116 Júlia Rosell Tethered Agonist Dependent ADGRL3 Signaling Activity In The G12/13 Pathway Peng Xiao Tethered Peptide Activation Mechanism of Adhesion GPCRs Stephanie Häfner The NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Anne Bormann Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl Dimitris Placantonakis Antibody-drug conjugates targeting CD97 in glioblastoma Gabriela Aust Critical role for CD97/ADGRE5 in the induction of allergic airway inflammation Hee-Yong Kim Characterization of Phenotypes Associated with GPR110 Deletion Vasiliki Karagiannakou A single cell GPCR map of thermogenic fat Gavin Zhang NovoiSMART - A new platform for GPCR antibody drug discovery

GPCR Articles News Get in Touch Item List This is a Title 01 This is placeholder text. To change this content, double-click on the element and click Change Content. Read More This is a Title 02 This is placeholder text. To change this content, double-click on the element and click Change Content. Read More This is a Title 03 This is placeholder text. To change this content, double-click on the element and click Change Content. Read More Menu • Home • Services • About Ready to collaborate? Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution across biotech, VC, and CRO teams. Get in touch ©2023-2025 All rights reserved by FindYooour, LLC & Dr. GPCR Corp Proudly created with Wix.com Connect • LinkedIn • Podcast • Dr. GPCR Ecosystem

Explore detailed information about our GPCR-focused University Courses. Learn about course content, instructors, and how to advance your expertise in drug discovery. Empower. Connect. Transform. Become part of the Dr. GPCR University Instructor community—where teaching is more than sharing knowledge; it’s about uplifting scientists and advancing GPCR discovery, together. Connecting scientists through knowledge, passion, and purpose. About Dr. GPCR University Dr. GPCR University is a global platform where scientists share their knowledge, inspire discovery, and advance GPCR research together. Our on-demand courses connect experts, students, and industry professionals through authentic, instructor-led learning—built by scientists, for scientists. Each contribution brings new perspectives and tools to advance the field. Instructors are recognized and compensated for their work, ensuring that every shared insight creates impact, visibility, and lasting value across the GPCR community. Course Formats You Can Teach At Dr. GPCR University , every instructor brings a unique voice, style, and rhythm to teaching. Our flexible course formats are designed to fit your time, depth, and teaching goals — whether you’re sharing a focused insight or leading a full exploration of GPCR science. You can also co-lead Full-Length Courses with up to three fellow instructors to share the workload and enrich the learning experience. 🧭 Full-Length Course Structure: 4 × 1-hour sessions Purpose: Deep, multi-session learning experience Best for: Comprehensive topics that require exploration and discussion ⚡ Short Course Structure: 1 session (2–4 hours of content) Purpose: Concise yet thorough coverage of key concepts Best for: Core methods, applied principles, or emerging topics 🔍 Mini Course Structure: 1 short lesson (1–2 hours of content) Purpose: Focused insights into a single theme Best for: Quick takeaways or specialized topics No matter the format, your course helps scientists learn, connect, and keep GPCR science moving forward — one discovery at a time. Instructor Benefits At Dr. GPCR University , we believe those who teach move science forward. As an instructor, you’re not just sharing knowledge — you’re shaping the next generation of GPCR scientists. We make sure your time, expertise, and contribution are recognized and supported every step of the way. 🌟 By teaching with us, you gain: ✔ Premium Membership for you and your team for one year (no credit card required) ✔ A global platform to share your expertise and reach scientists worldwide ✔ Full support with technical setup, editing, and course promotion — so you can focus on teaching We handle logistics so you can focus on what truly matters: delivering meaningful, high-quality education. To ensure lasting impact, each course becomes part of the Dr. GPCR University ecosystem — maintained, updated, and accessible to learners in the long term. Your name and expertise remain at the heart of the course, continuing to inspire scientists long after the sessions end. Together, we’re shaping the future of GPCR education — one course, one scientist, one discovery at a time. What You’ll Need to Provide to Teach a Course Welcome — we’re thrilled to have you join Dr. GPCR University . You bring the expertise; we’ll handle the setup, editing, and promotion. Here’s everything you’ll prepare to bring your course to life: 🧩 Step 1: Fill Out the Instructor Form Start by completing the Instructor Intake Form — it’s how we build your profile and course page. You’ll be asked for: Instructor info – name, email, affiliation, short bio, photo, and optional social media handles. Course details – title, format (short talk / mini-course / series), audience, main objectives, expected learning outcomes, key topics (≈ 250 words), recommended readings, and any co-instructors. Preferences & agreement – communication style, access to the Premium area, and acknowledgment of the instructor agreement (you’ll receive the full version right after submission). 🧱 Step 2: Plan Your Course Structure Decide how your course will flow — number of modules, duration, and teaching style. (See Course Formats above for ideas.) 🕙 Scheduling note: Courses are typically hosted Thursdays at 10 AM EST — a sweet spot for our global community. We’ll confirm your date together once your proposal is approved. 📝 Step 3: Prepare Your Content Create your teaching materials — slides, visuals, readings, or anything that helps learners grasp your message. Don’t worry — we’ll support you with templates and review tips along the way. 🎥 Step 4: Record a Short Video Chat You’ll have a quick recorded conversation with Dr. Yamina Berchiche about your course — what it covers, why it matters, and what students can expect. It’s relaxed, engaging, and helps introduce you to the community. 💬 Step 5: Join Your Private Course Group Once live, you’ll connect with your students in a private discussion space — perfect for questions, insights, and follow-ups. 💫 Step 6: Teach & Inspire Share your expertise with scientists around the world. Enjoy the experience, the visibility, and the impact — and receive recognition and compensation for your contribution. (See Instructor Benefits for details.) ✨ Your ideas, your voice, and your course will help shape the next chapter of GPCR discovery. Share Your Expertise with the World We’re here to support you from idea to impact. Start your journey as a Dr. GPCR University Instructor and help move GPCR science forward. Submit Your Course Proposal Masterclass Courses Previous Instructors Dr. Yamina Berchiche Dr. Sam Hoare Dr. Terry Kenakin Dr. GPCR Courses Reviews Dr. Hoare is very experienced in the field. What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended. The really unexpected was that the Q&A sessions reached the highest level—beyond excellent. I am a convert! I will keep Dr. GPCR and the offered resources in my work sphere Anonymous Thank you for bringing this course with Dr. Kenakin. I wish Dr. GPCR the best for the sake of promoting more educational opportunities that are sorely needed in the field Anonymous The content had enough depth to satisfy the hunger for theory while being full of practical knowledge Anonymous The best pharmacology teacher teaming up with the best GPCR community platform to help train and inspire the next generation of scientists. Also super-valuable for those of us learning how to teach pharmacology Anonymous Dr. Hoare's extensive and elaborative explanation of the topics at hand was excellent and very digestible. Thoroughly enjoyed learning from him Anonymous Dr. Kenakin is a leading expert in the field. Aside from his vast experience in drug development, not to mention his extensive publication record, Dr. Kenakin is a masterful teacher and communicator. Anonymous The course was very practical and easily translatable to experiments that we could do in our own labs. It was clear that Dr. Hoare is very in touch with the technical and human challenges we encounter in our work Anonymous Contact Contact us First name* Last name Email* Write a message Submit

Access expert CRO advisory services through the Dr. GPCR Ecosystem. Get guidance, strategies, and insights to optimize your GPCR research and drug discovery projects. Home About Services News Get in Touch Welcome CRO & Vendor Advisory Your Science Is Strong. Your Process Should Be, Too. I help CRO teams bring structure to collaboration—so your data gets acted on, not overlooked. When biotech partners trust your process, they come back again and again. You deliver high-quality data. But when timelines shift, expectations blur, or feedback loops break down, even the best work can lose momentum. Let’s turn your scientific rigor into results that move programs—and people—forward. Power My Discovery Biotech Clients Want Results - Not Confusion Every CRO I work with has great science—but clients still struggle to understand the value. Here's what I hear from biotech teams: “We’re not sure what we’re getting—or when we’re getting it.” “The science is solid, but the communication is scattered.” “The data looks fine, but it doesn’t help us make decisions.” Great science isn’t enough if clients don’t feel aligned, informed, and in control. That’s where I come in. How I Help CROs Deliver High-Impact Science That Biotech Teams Trust Biotech Clients Stay in Sync With Your Team I work to strengthen communication & collaboration: • Facilitate smoother communication between technical teams and biotech clients • Set clear expectations and deliverables to build trust and reduce delays • Align teams across roles—from assay execution to client updates Data Turns Into Decisions—Not Delays I help turn great science into clear deliverables • Define program objectives and guide assay plans that support partner decisions • Translate discovery data into clear, actionable formats biotech teams can use • Streamline deliverables to reduce review cycles and accelerate go/no-go calls & shorten timelines Your Science Stays Focused on What Matters We work together to position your CRO for growth • Refine your offering to match what biotech teams actually need • Position your services to shorten sales cycles and increase repeat business • Turn client feedback into improvements that boost trust and outcomes Here's What CROs Are Saying "Before working with Yamina, we were generating high-quality data across biotech programs but often navigating evolving expectations and goals from different stakeholders. After partnering with her, communication became clearer, deliverables were better defined, and collaboration across teams ran more smoothly. She helped streamline complex projects and made the CRO–client relationship more effective and productive." - Anne Marie Quinn, CEO Montana Molecular ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. Power My Discovery Send me a message First name* Last name Company name* Email* How Can I Help?* Send Message or Book My Call Menu Home Services About Ready to collaborate? Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution across biotech, VC, and CRO teams. Get in touch Connect LinkedIn Podcast Dr. GPCR Calendly ©2023-2025 All rights reserved by FindYooour, LLC & Dr. GPCR Corp Proudly created with Wix.com

Discover our comprehensive legal policies and disclaimers for Dr. GPCR Ecosystem, ensuring transparency and protecting your rights. Legal Policies and Disclaimers These legal documents and the agreement on Terms of Service (the “ATS”) for our websites ( Ecosystem.DrGPCR.com and DrGPCR.com ) (the “Website” or "Websites"). By using our Website, you agree to fully comply with and be bound by the following ATS each time you use our Website. Please review the following terms carefully. Dr. GPCR, Corp (“Dr. GPCR” or "DrGPCR") provides its Service (as defined below) to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com , DrGPCR.com . By accepting these Legal Policies and Disclaimers or by accessing or using the Service or Website, you acknowledge that you have read, understood, and agree to be bound by these Legal Policies and Disclaimers. If you are entering into this ATS on behalf of a company, business, or other legal entity, you represent that you have the authority to bind such entity and its affiliates to this ATS. If you do not have such authority, or if you do not agree with this ATS, you must not accept this ATS and may not use the Service. Dr. GPCR reserves the right to modify these Legal Policies and Disclaimers from time to time without prior notice. You can review the most current versions at any time on our Website. The revised terms and conditions will take effect upon posting. If you use the Service after this date, your continued use will constitute acceptance of the revised conditions. If any change to these Legal Policies and Disclaimers is not acceptable to you, stop accessing and using the Service. These agreements contain warranty disclaimers and other provisions that limit our liability to you. Please read these Legal Policies and Disclaimers carefully and in their entirety, as using, accessing, and/or browsing our Website constitutes acceptance of these terms and conditions. If you do not agree to be bound to each and every term and condition set forth herein, please exit our website immediately and do not use access and/or access it further. These Legal Policies and Disclaimers below must be accepted as a whole. You cannot accept one and ignore the others. Please read carefully our Legal Policies and Disclaimers to understand how Dr. GPCR conducts business Affiliate Policy Content and Conduct Policy Content Guidance Privacy Policy Terms and Conditions Trademark Policy

Transform your biotech idea or data into a clear, strategic roadmap with aligned biology, timelines, and CRO partnerships for faster results. Home About Services News Get in Touch Welcome Biotech Growth Wherever You Are in Discovery—Let’s Build a Plan That Moves You Forward Align your biology, timeline and CRO roadmap. Take your idea, platform, or early data and turn it into a strategic roadmap with clear decisions, timelines, and results fast. Start My Discovery Plan Too Much Uncertainty, Not Enough Progress You’re not alone. Biotech teams often tell me: “We have too many CROs and not enough clarity.” “We don’t know what matters most right now.” “We’re running experiments before aligning on strategy.” That's where I come in. How I Help Biotechs Accelerate GPCR Discovery with Clarity, Speed & Confidence Decisions, Not More Data We'll define what matters, when to decide, and how to act—based on your biology, not just what's easy to test. Prioritize assays based on project phase and decision points Map go/no-go logic that guides program momentum Focus resources where they’ll change outcomes No More Strategy Swirl I build structure that sticks—from CRO engagement to assay cascades—so your team isn't guessing what's next. Build experiment timelines aligned with strategy, not spreadsheets Set up clear deliverables across internal and CRO teams Keep cross-functional teams moving with shared structure Impress Your Board and Your Team Walk into every update with a confident story, backed by data, decisions, and momentum. Distill discovery progress into board-ready insights Craft milestone updates that tie data to strategy Present clear next steps that build investor confidence Trusted by Biotech Innovators Before working with Yamina, we were navigating challenging decisions around corporate and early discovery strategy. After bringing her in, we made confident progress on a key program and gained clarity around where to focus next. She helped bring teams together and created momentum across both science and execution. - Murat Tunabolyu, CEO Antiverse ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. Let's turn complexity into clarity—before your next program milestone. Start My Discovery Plan Send me a message First name* Last name Company name* Email* How Can I Help?* Send Message or Book My Call Menu Home Services About Ready to collaborate? Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution across biotech, VC, and CRO teams. Get in touch Connect LinkedIn Podcast Dr. GPCR Calendly ©2023-2025 All rights reserved by FindYooour, LLC & Dr. GPCR Corp Proudly created with Wix.com

Fast-track your biotech investments with VC Insights. Access expert guidance, vetted CROs, and data-driven strategies to invest smarter and move faster in GPCR drug discovery. Home About Services News Get in Touch Welcome VC Insights Fast Track Your Next Biotech Bet Get decision-grade data, vetted CROs, and expert guidance—so you move fast and invest smarter. I help you avoid costly delays, choose the right experiments, and unlock clear timelines that drive confident investment. Fast Track My Discovery The wrong CRO—or wrong experiments—can burn months and millions You're not here to fund academic detours. You're backing science that needs to move fast. But too often I hear: “We thought the experiments made sense—until the data didn’t help us decide.” “The CRO promised timelines they couldn’t hit.” “The team’s updates sound polished, but we can’t tell if they’re on track.” If you’ve said any of those, you’re not alone. That's where I come in : to pressure-test the science, align the strategy, and make sure every experiment earns its place. How I Drive Value Prioritize the Right Experiments Avoid noise. I help identify the experiments that truly matter—aligned to your milestones and inflection points. Translate project strategy into clear decision-driving assays Eliminate “nice to have” tests that stall timelines without payoff Match experiments to the specific phase and risk tolerance of the asset De-risk Your CRO Strategy I evaluate, select, and manage CROs that are fit-for-purpose—saving you time, cost, and rework. Audit and compare CRO options based on speed, quality, and fit Clarify deliverables and oversight to prevent rework and misfires Serve as a scientific bridge between VC, team, and CRO Move With Clarity and Speed Every week counts. I bring structure, decision frameworks, and momentum so your team stays on track. Build plans aligned to go/no-go moments, not busywork Drive regular check-ins that produce clear, actionable updates Anticipate delays and adapt quickly with contingency-ready paths " Yamina brings scientific clarity, leadership, and precision execution to complex pharmacological programs. I’ve worked with her on several discovery programs; in fragmented programs, she brought clarity and decision points that produced much better candidate progression. I am always delighted to work with Yamina as it always leads to an overall better and harmonious discovery program." - Terry Kenakin, PhD - UNC Chappel Hill ! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. Let's turn complexity into confidence—with the data you need to move forward. Chat about My Discovery Send me a message First name* Last name Company name* Email* How Can I Help?* Send Message or Book My Call Menu Home Services About Ready to collaborate? Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution across biotech, VC, and CRO teams. Get in touch Connect LinkedIn Podcast Dr. GPCR Calendly ©2023-2025 All rights reserved by FindYooour, LLC & Dr. GPCR Corp Proudly created with Wix.com

Discover the essence of GPCR Retreat, an international GPCR Event that empowers the GPCR field. Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat The GPCR Retreat focuses on advances in our understanding of how GPCRs operate in cell communication. The main goal of the GPCR Retreat is to provide a venue for students, post-doctoral fellows, and principal investigators from academia and industry to discuss and debate existing and novel concepts in GPCR biology. One of the core values of this international meeting is to promote interactions among all participants of all diversity backgrounds, particularly between trainees and principal investigators. Each year, approximately 2/3 of the participants are trainees. Registration to the GPCR Retreat is capped at 200 participants to promote an intimate environment. Most importantly, the GPCR Retreat dedicates time for two trainee symposia, an initiative that began in the Ottawa 2017 edition, to showcase the breadth of diversity in GPCR trainee communities. For the Ottawa 2017 GPCR Retreat, of the ten talks from trainees 80% were from women and 60% from visible minorities. Over the years, the meeting has grown into one of the most recognized international events in the field. That reputation has led to broad participation from the Great Lakes region and beyond. Conference History The GPCR Retreat is an annual joint meeting with the Club des récepteurs à Sept Domaines Transmembranaires du Québec that rotates around locations in Canada and the United States surrounding the Great Lakes region. The first Great Lakes GPCR Retreat was conceived, organized and held in London, Ontario, Canada in October 1999. The following year, the Great Lakes GPCR Retreat partnered with the annual symposium of the Club des Récepteurs à Sept Domains Transmembranaires du Québec . The meeting tours through many of the major universities in the Great Lakes region in both Canada and the United States. The past few GPCR retreats have been held in : Niagara-on-the-lake (2022) Bromont, Québec (2019) Detroit, Michigan (2018) Ottawa, Ontario (2017) Chicago, Illinois (2016) Toronto, Ontario (2015) Bromont, Québec (2014) Cleveland, Ohio (2013) London, Ontario (2012)

Expert support, trusted CROs, and ready-to-use tools to accelerate GPCR drug discovery, reduce risk, and advance your discovery-stage projects. Dr. GPCR Foundry: Accelerate GPCR Drug Discovery Move from idea to insight—faster, smarter, and with confidence. Partner with our nonprofit team for expert guidance, trusted CRO collaborations, and field-tested tools that de-risk your GPCR programs and keep momentum strong. 👉 Book a Free 30-min Strategy Call What Is the Dr. GPCR Foundry? In short: The Foundry gives you the right people, tools, and insight to move your GPCR programs forward — faster and with confidence. What Is the Dr. GPCR Foundry? The Dr. GPCR Foundry is a nonprofit platform designed to help biotech leaders accelerate GPCR drug discovery with precision, credibility, and speed. Here’s how we add value: Bridge early discovery to development: transform receptor concepts into validated, investment-ready programs. Leverage a trusted GPCR partner network: access curated CROs, consultants, and collaborators with proven track records. De-risk decisions: gain expert strategic guidance on study design, timelines, and partner selection before execution. Scale internal expertise: upskill teams through specialized GPCR programs and leadership-level insights. Partner through purpose: as a nonprofit, we align with your mission—accelerating breakthroughs, not billing hours. Why Biotechs choose Dr. GPCR Foundry? The Foundry is built for GPCR biotech companies at the discovery stage . 🔬 Validate your first target with confidence ⏱️ Scale programs faster with proven timelines 🤝 Access credible GPCR CROs and expert consultants 📚 Train and upskill your team with specialized programs 📢 Gain visibility through trusted media partnerships We connect you to: Specialized Consultants & KOLs Trusted GPCR CROs Learning Resources Media Visibility Opportunities Who is the Foundry for? The Dr. GPCR Foundry supports biotech teams working on discovery-stage GPCR programs who need expert guidance, trusted partners, or a clearer path forward. Wherever you are in your journey — from first target to scale-up — we’re here to help you move faster, smarter, and with confidence. You’ll benefit most if you’re: ✔ A GPCR biotech startup validating your first target ✔ An established biotech ready to expand or optimize discovery programs ✔ Looking for credible GPCR CROs and consultants to advance your work Explore Resources Expert Guidance — Built for GPCR Biotechs Get strategic clarity on your next discovery move — from target validation to translational strategy. Avoid costly missteps with data-driven, expert-backed recommendations. Gain confidence and direction with a customized roadmap aligned to your biotech’s goals and timeline → Book Your Free Strategy Call Specialized Training — Build GPCR Expertise Within Your Team Strengthen your team’s GPCR knowledge with structured, science-driven training . Learn proven experimental and analytical methods that accelerate discovery outcomes. Stay ahead of the curve with expert-led programs designed for real-world biotech challenges. → Explore the Dr. GPCR University GPCR Insights in Action Transform complex pharmacology into clear, practical understanding that drives discovery. Learn how to apply GPCR concepts and data to real-world research and development. Build confidence through expert-led lessons, case studies, and proven experimental strategies. → Explore Terry's Corner Visibility & Reputation — Amplify Your Scientific Voice Showcase your expertise and achievements within a trusted global GPCR network. Build credibility and visibility among scientists, biotechs, and CRO partners worldwide. Strengthen your organization’s presence through authentic storytelling and mission-aligned collaborations. → Email Hello@DrGPCR.org to learn more or Book a call below Team Advantage — Grow Together, Discover Faster Unite your scientists under one trusted GPCR learning hub. Give every team member access to the same expert-led, science-driven resources. Build collective expertise and alignment that accelerates discovery outcomes. → Explore Dr. GPCR University Team Membership Biotech Growth Workshops — Scale With Strategy Replace trial-and-error with structured frameworks tailored for biotech growth. Learn to scale confidently through data-driven, real-world case studies. Gain clarity and direction to move your biotech forward—faster and smarter. → Explore Timeline Strategy Help Your GPCR Discovery Program Succeed Work with the Dr. GPCR Foundry to accelerate your discovery programs with clarity, confidence, and trusted partnerships. Our core support areas: Discovery Consulting & Strategy Expert guidance to de-risk projects, refine strategy, and drive scientific progress. Visibility for GPCR Solution Providers Strategic media partnerships that connect your company with biotech innovators and showcase your expertise Training & Upskilling Specialized, insight-packed courses designed for discovery-phase GPCR teams. Tools & Templates Ready-to-use frameworks and resources tailored to the realities of discovery-stage GPCR work ✉ Contact Us Our Partners Join these innovative organizations already benefiting from the DrGPCR Foundry. Book Plan Your Next Move in GPCR Discovery Meet directly with Dr. Yamina Berchiche for a focused strategy conversation to align your goals, uncover opportunities, and map your next steps. Let's move your GPCR discovery program forward. Wherever you are in your discovery journey, the Foundry helps GPCR biotech companies move faster and reduce risk. Let's discuss your next step.

Discover Media Partner Packages with Dr. GPCR Ecosystem. Amplify your brand, reach a targeted scientific audience, and showcase your organization in the GPCR community. Elevate Your GPCR Focused Company Visibility Reach 1400+ GPCR researchers. Build Scientific Credibility and Brand Recognition in the GPCR Ecosystem Only 12 partners are accepted per year. Partner with us Today! Who Media Partnerships Are For Strategic Partnerships are ideal for GPCR-focused companies that want to: Strengthen brand credibility and recognition within the GPCR research community Be consistently visible across trusted educational and content platforms Associate their brand with high-quality science, experts, and long-term ecosystem initiatives Build awareness and trust over time — not chase immediate leads If your primary goal is to drive inbound inquiries or make your services discoverable at the point of need, the GPCR CRO Bank may be a better fit. Connect With The GPCR Community You've built incredible tools, services, or platforms for GPCR researchers. But are the right scientists discovering them? Dr. GPCR is the world's largest nonprofit community focused on GPCRs. As a media partner, you'll gain trusted access to an engaged audience of academic researchers, biotech teams, and drug discovery innovators—without having to fight for attention. We only accept 12 media partners per year. Each one receives personalized support, targeted visibility, and a seat at the table in the GPCR ecosystem. Ready to share your company with the GPCR world? With only 12 media partner seats available each year, every partner gets intentional placement, dedicated support, and real visibility. No noise. No clutter. Only connections. Why Partner with Dr. GPCR? As a media partner, you'll be featured across our nonprofit platform, trusted by thousands of GPCR scientists and biotech professionals. 🎯 Reach Qualified Researchers Connect with scientists who are actively looking for tools like yours, without the noise of general platforms. 🤝 Build Trust Develop content that speaks their language and establishes your credibility in the GPCR research community. 🌐 Join a Curated Ecosystem Become part of a collaborative, curated ecosystem—not just another name on a crowded vendor list. With only 10 seats remaining in 2026, we're focused on quality over quantity - and on partnerships that deliver long-term value to the field. 12 Partners Accepted Per Year 1400+ GPCR Scientists Reached What You Get as Media Partner Becoming a Dr. GPCR media partner means more than visibility. It means integration into a trusted scientific ecosystem that's built to elevate your story. These touch points are designed to reinforce brand presence and credibility through repeated, trusted exposure — not direct lead generation. 🎙️ Featured Podcast Episode ✓ Be the guest on a dedicated episode of the Dr. GPCR Podcast ✓ Feature up to 3 team members to share your story ✓ Distributed across podcast platforms and social media 📄 Custom Company Page ✓ Permanent company profile on the Dr. GPCR Ecosystem ✓ Logo, branding, and description of your mission ✓ Contact links and key highlights ✨ Logo positioning ✓ Strategic Partner logos are featured across multiple high-traffic ecosystem pages, creating repeated visual association with trusted GPCR content and resources. 📬 Newsletter Visibility ✓ Featured in our highly read weekly newsletter ✓ Tell your story with context, clarity, and purpose ✓ Bonus: Mentioned in podcast intros/outros 📣 Social Media Promotion ✓ Engaging posts about your organization ✓ Targeted to GPCR researchers and biotech professionals ✓ Shared on LinkedIn and X (Twitter) 👩🔬 Premium Licenses ✓ 10 Scientists Premium Accounts ✓ 3 Non-Scientists Premium Accounts 📝 Blog Contributions ✓ Contribute to blog posts on the Dr. GPCR platform as a valued partner ✓ Share insights on product launches, scientific discoveries, or customer stories ✓ Reach a targeted scientific audience with your contributions. 🎤 Co-Branded Events & Training ✓ Collaborate on webinars and virtual training sessions to showcase your expertise ✓ Host educational events that focus on GPCR research ✓ Engage directly with the GPCR research community through these initiatives Previous Partners Join these leading organizations in the GPCR research ecosystem Book Book a 30-minute Strategy Call with Yamina Ready to Connect with the GPCR Community? With only 10 spots remaining for 2026... Secure your place in our exclusive media partner program today.

Join the forefront of GPCR research at the Dr. GPCR Summit! Embracing innovation and technology, we connect global scientific communities. Experience talks spanning time zones, with options for live or pre-recorded presentations. Uncover groundbreaking insights in GPCR science together. Learn more. Meet Dr. GPCR Summit Partners - Click to Explore - Dr. GPCR Summit 2021 Welcome to the official page of the Dr. GPCR Virtual Summit 2021! << Live talk schedule >> << Pre-recorded talk list >> The program is complete! Don't miss a chance to listen to 25+ scientific talks, which will only be available for those who registered during the Summit. Get your All-Access ticket before they're gone by visiting Eventbrite today! Got your All-Access ticket already? Special shout out to our partners! Check your inbox this week, you'll be able to invite a friend or colleague to join the Summit for Free! Proceeds from the ticket sales will be used to provide the best three trainee talks with fantastic prizes, including a personalized autographed copy of Dr. Lefkowitz's biography. Present a pre-recorded talk and get free access to the entire Summit! Hurry, the deadline to submit your talk is Friday, September 10th, 2021, at midnight EST. If you're facing financial difficulties or are a trainee who would like to attend but can't submit a pre-recorded talk, reaches out to us now! The live talks will be held on Zoom, and everyone who registered will be able to ask their questions to the speakers all week on Microsoft Teams! You'll also be able to meet our partners on Microsoft Teams. Make sure you have a profile picture set for both Zoom and Microsoft Teams! Everyone is welcome to present their work (students, postdocs, PI's, biotech, pharma companies)! There are no posters! All pre-recorded talks will be available during the summit for free with registration. All live talks will have a $5 attendance fee/ talk You can get full access to all the talks for $100 For Speakers Step 1: Let us know that you'd like to present your work by filling out this short form here Step 2: Prepare your video abstract and your presentation (pre-recorded or live)* Step 3: Click here to send us your pre-recorded presentation or click here*** to submit the information to your live presentation before August 5th, 2021. ***All live talks are now scheduled Please provide us with your pre-recorded presentation by September 10th, 2021 *Note: Scroll down to find resources to help you prepare your video presentation, and don't hesitate to get in touch if you need help. Contact us at Hello@DrGPCR.com Some housekeeping items first We strongly suggest you carefully consider what type of information you share in your presentation. We will do our best to keep the Summit a closed event, but Dr.GPCR is not responsible for any loss of intellectual property. How will I access the talks during the Summit? You will receive an email from Eventbrite containing the relevant information before the summit. Be sure to register. How can I sponsor the 2021 Summit? Please visit our Sponsor Page to learn more about sponsorship opportunities to sponsor the Summit and the DrGPCR Ecosystem. For more information, please email us at Hello@DrGPCR.com In what form can I submit my abstract? Abstract submission can be in the form of classical text abstract or in the form of a short (max. 3 minutes) video. This is an excellent opportunity to be as creative as you want to be. We recommend writing a 200-300 word abstract, giving you enough information to provide a great video abstract in under 3 minutes. How will I present my talk? You can pre-record your talk. We recommend submitting pre-recorded talks. What does this mean? You send us the video of your full-length talk, and we will take care of the rest. Alternatively, you can provide us with the embed code to make your presentation available during the Summit. Pros: You can polish your recording to your satisfaction. Anyone can watch it from anywhere, even multiple times. Imagine binge-watching your favorite talk over and over whenever you want to during the Summit. Cons: It may take more time to record an excellent presentation, but nothing is impossible! Click here to submit your pre-recorded presentation. Can I present a live talk or event? How? In case you'd like to present a talk live, we'll help with it. Pros: It may take less time to prepare for the presentation Cons: You may make mistakes since it's a live event, and if you decide to keep your talk live only, participants can watch it only once. *Tip Become a DR. GPCR Member by creating your own personalized page. Read more about becoming a member here . If you need help preparing your pre-recorded video and video abstract check out these resources: How to record your talk in PowerPoint 365 How to record your talk using a previous PowerPoint version How to record your talk using Keynote on a Mac Do you have any questions? Email us at Hello@DrGPCR.com << Live talk schedule >> << Pre-recorded talk list >> Meet Dr. GPCR Summit Partners - Click to Explore - Tags Dr. GPCR Summit Dr. GPCR Summit 2021 Dr. GPCR Summit 2021 Pre-Recorded Talks Dr. GPCR Summit 2021 Live Talks

Join the forefront of GPCR research at the Dr. GPCR Summit! Embracing innovation and technology, we connect global scientific communities. Experience talks spanning time zones, with options for live or pre-recorded presentations. Uncover groundbreaking insights in GPCR science together. Learn more. Dr. GPCR Summit We live in a new world, and we think it's an opportunity to try new things and use current technologies to help us connect and spread scientific advances in the GPCR field. Our goal is to allow everyone in the GPCR community to get access to the talks through the entire length of the event independently of their time zone. This means that presenters will have the option of providing a pre-recorded talk or giving a live presentation. More information is outlined below. See Schedule See Schedule See Schedule

Join the GPCR Retreat: Exploring the Frontiers of GPCR Biology! Engage with leading minds from academia and industry, fostering discussions on cell communication and novel concepts. Embrace diversity in a limited-capacity event fostering mentor-trainee interactions. Retreat 2023 About Program Registration Logo Contest Committee Sponsors 22nd GPCR Retreat Fairmont Le Château Montebello, Québec, Canada November 2-4, 2023 We are pleased to welcome you at Le Château Montebello , the 22nd Annual Great Lakes G Protein-Coupled Receptor Retreat held jointly with the Club des Récepteurs à Sept Domaines Transmembranaires du Québec. The meeting will be held on Nov. 2-4, 2023 at the Chateau Montebello, Québec. The Chateau Montebello is an exceptional venue, and is located 1 hr from Ottawa, or 1.5 hr from Montreal in the beautiful Laurentian Mountains of Canada. The fall colors of the leaves are spectacular, and the weekend of science is an intense and interactive experience, and a great training environment for our students and post-doctoral fellows. The meeting is launched on Thursday with two Trainee Symposia and the Plenary Lecture, followed by 6 symposia on Friday and Saturday and the closing Keynote Lecture. The deadline for registration is September 21, 2023. For the 22nd edition, the Organizing Committee has again lived up to the expectations by putting together an outstanding program with a special thought for Marc Caron (1946-2022) to commemorate his great contributions to the GPCR and Neurosciences fields. Dr. Kathleen Caron of the University of North Carolina at Chapel Hill, unquestionably one of the pioneers involved in deciphering how receptor activity-modifying proteins or RAMPs regulate GPCR function, is confirmed as Plenary Speaker of the inaugural Marc G. Caron keynote lecture on November 2nd. Additionally, there will be a Marc G. Caron Honorary Symposium by Caron Lab alumni to honor his memory. We have also confirmed Dr. Arthur Christopoulos of Monash University in Australia, one of the pioneers in the medicinal chemistry, computational and mathematical modelling of GPCRs, as Plenary Speaker of the Hyman B. Niznik keynote lecture , which will close the conference. The program will include also world-class and diverse GPCR scientists working in the arenas of structure and signaling, neuroscience, cancer, translational and model systems. As in previous editions, trainees are more than welcome to this unique meeting. Indeed, for the Montebello 2023 edition, we have organized two trainee symposiums to acknowledge formally the participation of our graduate students and post-doctoral fellows. Additionally, each symposium of the GPCR Retreat 2023 will include one trainee short talk selected from abstracts. Trainees of diversity groups are strongly encouraged to register to the meeting and submit an abstract for consideration for the trainee symposia and selected trainee short talks. Your participation has already made this unique event a success. We are thrilled by the overwhelming interest in this event by the GPCR research community. We trust that the collegial and intimate atmosphere provided by Le Château Montebello will be suited for an environment where graduate students, postdoctoral fellows and principal investigators can have stimulating discussions and debates on GPCR research presented at this meeting. We would like to thank all our Sponsors for their ongoing generous support of the meeting. Without their support, this meeting will not be possible. If you have any suggestions or comments for either this Retreat or future meetings, we look forward to receiving your feedback. Finally, Bienvenue and we hope you will enjoy your stay in Montebello and find the Retreat stimulating and satisfying. Sincerely , The Organizing Committee Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Explore the world of GPCRs with Dr. GPCR Podcast! Join industry leaders as they share insights, stories, and groundbreaking discoveries, enriching our understanding of GPCRs. Delve into the science behind these vital components shaping our collective knowledge. Welcome to the Dr. GPCR Podcast - The Voice of the Community Conversations with the world’s leading GPCR scientists. Exploring discoveries, careers, and ideas shaping human health. In each episode, we sit down with leading experts to explore their career journeys, groundbreaking discoveries, and the impact of their research on our shared understanding of GPCR biology. Launched at the height of the pandemic, the Dr. GPCR Podcast was created with three goals: Share discoveries – Highlight the latest advances in the GPCR field. Amplify voices – Provide scientists a platform to showcase their work. Inspire the future – Motivate the next generation to pursue GPCR research. At its core, Dr. GPCR’s mission is simple yet ambitious: to bring the GPCR community together - across borders and disciplines - to connect, exchange, and collaborate in order to improve human health through a deeper understanding of GPCR biology. Latest Podcast Episodes More podcast episodes Dr. GPCR Podcast Audience Survey We are currently planning our next season and need your help. This short survey will help us understand your needs to bring you exciting and informative content. We also know that you are busy, which is why we designed this short survey that should take you 5 minutes. Fill out this form Be our Guest In each episode, we chat with an expert about their career trajectory, discoveries, and how their research contributed to the shared pool of knowledge about GPCR biology. We’d love to have you on our podcast. To be a guest, fill out the form below, and we’ll be in touch in 48 hours. Fill out this form What others are saying about this podcast Really enjoyable science podcast! Dr. Yamina Berchiche interviews leading GPCR scientists on this vibrant, entertaining podcast. I really appreciate the way the podcast educates and mentors, particularly towards junior scientists but also to the community as a wholen Yamina is a great interviewer, getting insight and personal history from her guests. Am very grateful for Dr GPCR livening up the week in these difficult times! Sam @Pharmamechanic I enjoy the breadth of questioning that goes beyond just the science, and reveals a bit about the scientists as individuals/mentors/people. Anonymous Great initiative, thanks. Carrier paths, choosing research topics, switching fields, late start, failures and successes. Anonymous This came at just the most perfect time. I hadn't heard a scientific talk outside my lab since February and was starved to hear someone else talk passionately about GPCRs. I've listened to the episodes multiple times and it's just like being at a conference getting new ideas. I just couldn't be happier y'all created this podcast. Anonymous I think it's really well done. I'm genuinely interested to see how it evolves and grows over time, as I feel it has the potential to develop into something even more impactful. Anonymous Listen and subscribe where you get your podcasts

Monitor GPCR internalization in real time with pHSense™ – no-wash, TR-FRET reagents from Revvity. Fast, clear, live-cell receptor trafficking detection. Unlock microscopy-free real-time GPCR internalization with pHSense pHSense™ probes are optimized reagents for plate readers, specifically designed to study internalization using time-resolved fluorescence (TRF) detection. They offer high-sensitivity, no-wash detection of internalization events in a scalable, plate-based format. This technology supports robust analysis even at low endogenous receptor expression levels. Suitable for basal/constitutive and agonist-induced GPCR internalization Compatible with TRF plate readers No-wash protocol simplifies workflow Formats available for modified GPCR cell lines or unmodified primary cells Explore pHSense Products Powered by Revvity’s legacy of innovation in translational science. Dr. GPCR Ecosystem Partner Visit Website Precision Tools for Translational Science Revvity is a global leader in life science innovation, delivering tools and technologies that bridge the gap between discovery and real-world impact. With decades of expertise and an unwavering focus on precision, Revvity empowers scientists to simplify complex workflows, accelerate discovery, and drive breakthroughs in drug development, diagnostics, and disease biology. Whether you’re decoding signaling pathways or designing the next generation of therapeutics, Revvity isn’t just a provider—they’re your partner in discovery. Discover pHSense™ portfolio From binding to signaling to internalization: Cell-based fluorescence assays for complete GPCR characterization The principle of pHSense™ relies on the pH-dependent fluorescence activation of a europium-labeled antibody to monitor receptor internalization in live cells. Neutral pH = low signal: The probe is minimally fluorescent at extracellular neutral pH (≥7), which means it doesn't emit a strong signal when bound to the surface. Internalization into acidic compartments = signal activation: Upon receptor-mediated endocytosis, the probe is internalized into acidic intracellular compartments (like early/late endosomes and lysosomes). The europium complex becomes increasingly fluorescent as the pH drops, enabling dynamic tracking of internalization. Time-Resolved Fluorescence (TRF) = High Signal-to-Background: Europium’s long-lived fluorescence allows TRF detection, which effectively filters out short-lived background signals. This results in high sensitivity and specificity in no-wash, plate-based live-cell assays. pHSense™ Eu Anti-FLAG Designed for the detection of FLAG-tagged receptor and membrane protein internalization. View Product pHSense Eu SNAP Labeling Reagent Can be used to label receptors and membrane proteins carrying an extracellular SNAP sequence with a pHSense probe to monitor their internalization View Product pHSense Fab Anti-Human or Anti-Mouse IgG Fab fragments for monitoring GPCR and antibody internalization in unmodified cells The Fab Anti-Human IgG Eu-conjugate can be used in combination with a neutral anti-GPCR to address unmodified receptors in primary cells View Product The Fab Anti-Mouse IgG2 Eu-conjugate is suited to study mouse biologics targeting GPCR and confirm their internalization effects on receptors. View Product The pHSense™ Advantage Clarity. Consistency. Compatibility. Purpose-Built for Live-Cell Internalization Assays The pHSense™ family of europium-labeled, pH-sensitive reagents is designed to simplify and accelerate the study of GPCR and membrane protein internalization in live cells. These reagents are fully compatible with plate-based, no-wash workflows and use time-resolved fluorescence (TRF) to eliminate background noise—delivering clear, quantifiable signals as targets move into acidic intracellular compartments. What Sets pHSense™ Apart ✅ Time-resolved detection minimizes background noise, which enhances detection sensitivity. ✅ No-wash protocol preserves cell integrity and kinetic detection. ✅ High-throughput ready: faster time-to-results and streamlined data acquisition. ✅ Comprehensive validation: validated for GPCRs, but also antibodies and ADCs. ✅ Versatility across suspension and adherent cells The Full GPCR Toolkit by Revvity Every step of the signaling cascade. One trusted source. GPCRs are among the most powerful and complex targets in biomedical research. Revvity offers a comprehensive reagent portfolio to match that complexity—supporting every stage of the signaling pathway, from ligand binding and G-protein activation to intracellular signaling readouts. With formats including TR-FRET, radioligand binding, cAMP, IP-One, and phospho-protein assays (ERK, AKT, CREB, MEK), this toolkit is built for speed, reproducibility, and translational insight. Proprietary no-wash technologies help reduce hands-on time while maintaining exceptional data quality—so you can move fast without compromise. View Reagents Explore Revvity’s GPCR Assay Technologies Tools designed to illuminate every step of GPCR signaling—from binding to downstream response. Ligand binding Measure receptor engagement with high sensitivity using TR-FRET, radioligand, and Fluorescent Tag-lite® formats. G-Protein Activation Quantify Gs, Gi, and Gq activation in real time with cAMP, GTP, and IP-One assays. Arrestin Recruitment Detect β-arrestin recruitment with TR-FRET and luminescence assays tailored for biased signaling studies. Intracellular Signaling Track key downstream events like ERK, AKT, and CREB phosphorylation with high-throughput precision. Build Your GPCR Assay Workflow Meet the Team behind pHSense™ Eric TRINQUET Sr Director Life Sciences Reagents, Revvity Eric Trinquet is a recognized expert in the field of immunoassays and fluorescence technologies. He currently leads Revvity's Research and Development activities, focusing on biochemical and cellular assay platforms related to Life Sciences Reagents. Before joining Revvity, Eric worked for Cisbio Bioassays first as Director of Technological Development and then as R&D Director. His career is marked by significant contributions, from introducing HTRF technology in the field of high-throughput screening to developing innovative solutions such as the IP-One kit for studying G Protein-Coupled Receptors (GPCRs) and the Tag-lite platform. Elodie DUPUIS R&D Senior project manager, team leader. Elodie Dupuis earned her Master’s degree in biology and biotechnology engineering from the University of Sciences of Nîmes and the Ecole des Mines engineering school (France) in 2009. She then joined Cisbio Bioassays, and later Revvity, as project leader and team manager in the Research & Development department, leading her team on the development of innovative HTRF™ and AlphaLISA™ kits for pharma, biotech, and academic partners. Through her research contributions, she has co-authored numerous scientific publications and holds several patents as an inventor. She has been leading collaborative projects with public research institutes and pharmaceutical companies, most notably the joint Revvity/Institute of Functional Genomics team, EIDOS. In 2020, together with her team, she initiated a long-term research effort that enabled the creation of a new and innovative portfolio for GPCRs, antibody drug conjugates, and several other applications: pHSense™. 2025 marked the commercial launch of the first pHSense products by Revvity. Mathis LAFFENETRE Product Manager, Immunoassay Reagents. Mathis holds a biotechnology engineering degree from the National School of Biomolecule Technology of Bordeaux and an MS in biomedical business management from the Grenoble School of Management. He joined Revvity (then Cisbio) in 2016 as part of the scientific marketing effort to build brand recognition for the HTRF technology and accelerate the company’s reagents use in academic labs, biotech companies, and pharma. In the following years, he held several marketing and strategic positions in France and the US, primarily related to the Immunoassay portfolio. As of 2025, he is part of the Immunoassay & Imaging Reagents Portfolio group as a product manager for the GPCRs, and is responsible for supporting the adoption and expansion of the reagent portfolio into the hands of scientists and researchers. Inside the Science: A Conversation with Revvity's Dr. Eric Trinquet From Rare Earth Probes to Internalization Assays: The pH Sense Story If you’ve ever used HTRF or wondered what goes into making a product worthy of your next experiment, this is your backstage pass. More about this conversation Our Partnership Dr. GPCR Spotlights Revvity’s pHSense™ Reagents for Real-Time GPCR Internalization A new reagent family designed to unlock high-throughput internalization workflows—now featured across the Dr. GPCR Ecosystem Boston, MA – September 2025 — Dr. GPCR, the global nonprofit platform dedicated to advancing GPCR research and drug discovery, is proud to spotlight the launch of pHSense™, a new reagent family from Revvity designed to bring unprecedented clarity, speed, and scalability to the study of receptor internalization. Internalization is a core—but often overlooked—dimension of GPCR biology. Traditionally, studying it has meant long workflows, low throughput, or expensive imaging platforms. pHSense™ changes that by combining europium-based, pH-sensitive probes with no-wash, live-cell protocols and TRF-based detection—making it possible to monitor internalization in real time, in standard plate-based assays. “When we saw dose-dependent internalization in endogenous GLP1R cells—without microscopy—that was the turning point,” said Dr. Eric Trinquet, Director of Research and Development at Revvity. “We knew pHSense could offer something truly new to the GPCR field.” A Tool Designed for Real Research Needs Built on more than two decades of GPCR assay innovation, pHSense™ was developed to overcome three persistent barriers in internalization studies: Complexity of imaging-based workflows Lack of scalability for high-throughput screening Difficulty detecting endogenous receptor activity With pHSense™, scientists can finally move beyond proxy readouts and track GPCR internalization as it happens—even at physiological expression levels. All four formats are validated in well-established models like GLP1R and Mu opioid receptor (MOR), and are compatible with HTRF plate readers already used in most labs. Related Articles How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs Discover how Dr. Eric Trinquet, creator of HTRF and IP-One assays, turned failure into breakthrough tools for GPCR science. Learn why play, serendipity, and partnerships fuel innovation—and how this mindset can transform your research and biotech career. Dr. GPCR Podcast Oct 16, 2025 4 min read The Truth About GPCR Product Launches: Years in the Making What it really takes to launch a GPCR product—years of failure, science, and strategy. Go behind the scenes of pH-Sense with Revity’s Dr. Eric Trinquet. Dr. GPCR Podcast Oct 8, 2025 4 min read Innovative Data-Driven Solutions: The pHSense Revolution A powerful new tool tracks GPCR internalization in native cells—no imaging, no overexpression. Learn how pH Sense changes the game for drug discovery. Dr. GPCR Podcast Sep 26, 2025 3 min read Dr. GPCR Ecosystem Partner Contact Revvity

Learn about Celtarys Research through the Dr. GPCR Ecosystem. Explore their innovative GPCR projects, collaborations, and contributions to cutting-edge drug discovery. Partnership Dr. GPCR x Celtarys Reseach Empowering medicinal biochemists Celtarys empowers medicinal biochemists by providing innovative fluorescent probes that de-risk the pre-clinical drug discovery phase. Our proprietary conjugation technology and unparalleled scientific expertise ensure researchers can confidently advance their projects with greater precision and reliability. Visit Website About Celtarys Research Celtarys Research develops and commercializes new chemical tools to spread the use of fluorescence-based methods in the pre-clinical phase of drug discovery. Our proprietary chemical conjugation technology allows us to grow, in a competitive manner and in a short time (<3 months), customized fluorescent ligands with optimal pharmacological and photophysical properties for any druggable target. We have a catalogue of over 30 fluorescent ligands for different families of GPCRs, including adenosine, dopamine, serotonin, cannabinoid and muscarinic receptors. We also offer our expertise in the form of custom development services, where we tackle challenging targets and synthesize probes with the most suitable properties for your needs. Meet the Celtarys Team Wilson Gomes CEO Wilson Gomes holds a Mechanical Engineering degree, an MBA from the University of North Carolina, and completed the General Management Program at Harvard Business School. He has over 20 years of experience in the medtech and diagnostics industries, having held senior roles at Johnson & Johnson and Danaher across the EMEA region in sales, marketing, and general management. He joined Celtarys as CEO in 2024, where he is responsible for driving strategy and growth. His focus is on expanding commercial reach and accelerating the adoption of the company’s GPCR assay technologies. Maria Majellaro Co-Funder and CSO Dr. Maria Majellaro earned her degree in Pharmaceutical Chemistry and Technology from the University of Bari and completed her PhD in Biomolecular Sciences in Pharmacology and Medicine as “Doctor Europeus” in 2018. She then joined the University of Santiago de Compostela as a postdoctoral researcher in Prof. Eddy Sotelo’s group, contributing to the IGNICIA tech transfer project and the validation of Celtarys’ core technology. In 2021, she co-founded Celtarys and now leads the company’s scientific direction. Her work focuses on organic synthesis, medicinal chemistry, and the development of GPCR-targeted tools for pharma, biotech, and academic partners. Podcast Episode Baking Molecules, Building Probes: When Chemists Think Like Biologists Episode #168 • Dr. GPCR Talks with Dr. Maria Majellaro "We always start with the problem, then generate the right compound using our chemistry. It’s about enabling biology.” Celtarys News & Updates C5aR Fluorescent Ligands: Need for new Research Tools GPCRs are one of the most important families of therapeutic targets in the pharmaceutical industry. They are involved in several pathologies, ranging from neurological, oncological, degenerative, metabolic, immunological… around a third of the drugs in clinical use are GPCR ligands Lucía from Celtarys Research 1 minute ago 7 min read Using Live-cell High-Content Screening to Characterize CB2 Ligands: Insights From 16 Synthetic Cannabinoids Live-cell high-content screening (HCS) offers an increasingly valuable alternative. By quantifying ligand–receptor interactions directly in intact cells, HCS allows researchers to observe binding events under near-physiological conditions while simultaneously generating image-based evidence to support numerical affinity estimates. For targets such as CB2, where nuanced shifts in receptor conformation affect signaling outcomes, a whole-cell environment can strengthen early-sta Lucía from Celtarys Research Dec 9, 2025 5 min read 1 2 3 4 5 Our Partnership Dr. GPCR and Celtarys Research Join Forces to Expand Access to Innovative GPCR Tools Boston, MA and Santiago de Compostela, Spain — June 3rd, 2025 — Dr. GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, is proud to welcome Celtarys Research to its partner ecosystem. This collaboration aims to amplify the visibility and adoption of Celtarys’ cutting-edge fluorescent ligand technology and accelerate the development of GPCR-targeted therapeutics. Celtarys Research develops high-quality, fluorescently labeled ligands and innovative chemical biology tools to support real-time, non-radioactive GPCR assays. These tools enable high-resolution binding studies, kinetic analysis, and live-cell imaging, empowering both academic and industrial scientists to uncover GPCR biology with greater precision and speed. “We’re thrilled to partner with Celtarys and introduce their high-performance fluorescent ligands to our global GPCR community,” said Dr. Yamina Berchiche, Founder and CEO of Dr. GPCR. “These tools can dramatically improve how scientists measure ligand-receptor interactions, visualize binding in live cells, and design better experiments, core to advancing GPCR-targeted discovery.” “Dr. GPCR provides a unique platform to reach scientists at every stage of GPCR research,” said Wilson Gomes, CEO of Celtarys Research. “This partnership will help accelerate the adoption of our chemical tools and foster collaborations that turn receptor biology into therapeutic breakthroughs.” “We’re excited to support the GPCR community with tools that deliver clarity, sensitivity, and speed,” added Dr. Maria Majellaro, CSO of Celtarys. “Working with Dr. GPCR allows us to engage with researchers worldwide who are shaping the future of receptor-targeted therapies.” To explore Celtarys Research’s catalog and learn more about their GPCR tools, visit https://www.ecosystem.drgpcr.com/celtarys-research Services & Expertise NEW! High Content Screening Service Live‑cell HCS imaging in HEK‑293T–hCB2R with fluorescent ligand CELT-331; confocal capture on Operetta CLS. GPCR Expertise Specialized knowledge in adenosine, dopamine, serotonin, cannabinoid and muscarinic receptors for advanced research. Fluorescent Probes Innovative fluorescent probes that de-risk the pre-clinical drug discovery phase with optimal pharmacological properties. Custom Development Customized fluorescent ligands developed in less than 3 months with optimal properties for any druggable target. Product Catalog GPCR Ligands Our GPCR fluorescent ligands are the ideal solution for your High Throughput Screening (HTS) needs. GPCR Functional Assay Fluorescent GTPγS enables sensitive, non-radioactive GPCR activity assays for drug discovery. Custom Development Tailored fluorescent probes designed for unique research requirements. Contact Celtarys Research First name* Last name Email* Write a message Submit Get in Touch Address Avda. Mestre Mateo 2, Santiago de Compostela, 15706, Spain Email Website LinkedIn

Join the forefront of GPCR research at the Dr. GPCR Summit! Embracing innovation and technology, we connect global scientific communities. Experience talks spanning time zones, with options for live or pre-recorded presentations. Uncover groundbreaking insights in GPCR science together. GPCR EVENT Dr. GPCR Summit 2022 Dr. GPCR Ecosystem Partners Welcome to the official page of the 3rd edition of the Dr. GPCR Summit This year the Summit will be held between October 10th and 16th. You can join us for free when you become a Dr. GPCR Ecosystem site member, which is also free! The content of the Summit will only be available to site-members who must be approved to join us. You can participate: As an attendee by becoming a site member. It only takes a minute, and it's free With your pre-recorded talk By presenting a poster on Wonder By giving a live talk. Space is limited, and we will do our best to accommodate your request For Speakers and presenters: Make sure you are registered as a site member to get access to the entire Summit for Free! Verify that you talk data and time are in your calendar. You can verify it too by checking out the schedule on our website. Live talks should be 30 mins with 15 mins Q/A. Live trainee talks should be 15 mins with 5 mins Q/A. All live talks will be on Zoom, the link will be added to your calendar invite and will be available here on our website but only visible to registered site-members. Similar to previous years: The meeting will be virtual (on Zoom) to host as many participants as possible Live talks will be hosted on Zoom from October 10th to the 14th Trainees are invited to participate by presenting a trainee talk, a poster, or a pre-recorded talk Presentation prizes will be available for the best trainee talks and posters We are also trying out a few new things: Networking and poster sessions on Wonder A full day dedicated to trainee talks Workshops and panel discussions In case you'd like to present your work, you'll need: Become an Ecosystem site member Pick the correct form and submit it before September 30th, 2022 You'll need a 1-minute video abstract in addition to the written version You can always email us with any questions and comments at Hello@DrGPCR.com << Submit your live talk details >> << Submit a pre-recorded talk >> << Submit your poster >> << Live talk schedule >> << Pre-recorded talk list >> << Poster presentation list >> Tags Dr. GPCR Summit Dr. GPCR Summit 2022 Dr. GPCR Summit 2022 Schedule Dr. GPCR Summit 2022 Details Dr. GPCR Summit 2022 Pre-Recorded Talks Dr. GPCR Summit 2022 Live Talks Dr. GPCR Summit 2022 Poster Presentations Submit Pre-Recorded Talk Presentation for Dr. GPCR Summit 2022 Submit Live Talk Presentation for Dr. GPCR Summit 2022 Submit Poster Presentation for Dr. GPCR Summit 2022

Equip your research team with expert-led GPCR pharmacology training. Get 25% off Annual Premium Memberships for teams of five or more. Activate in days. Home Courses Articles About Log In / Sign Up Equip Your Team with Terry Kenakin’s Pharmacology Expertise Shared depth in GPCR pharmacology—built for scientific teams One team membership. Shared pharmacology expertise. Faster, better decisions. Train 5+ team members and receive 25% off annual access. Access monthly courses, live AMAs, and hard-won insight from 40+ years shaping GPCR pharmacology. Activate Team Membership What Your Team Gets? Proven frameworks for drug discovery Learn anytime, anywhere — flexible for busy discovery scientists Shape the curriculum — submit topics you and your team want covered next Weekly new courses — stay ahead of the science Designed for biotech, pharma & academic researchers Live monthly AMA with Dr. Kenakin — get expert answers How It Works? 1️⃣ Prepare Your Team Gather at least 5 team members . Each person must have or create a Dr. GPCR Ecosystem account. 3️⃣ Confirm and Pay Securely Review your submission and complete payment. You’ll receive a confirmation email immediately. 2️⃣ Submit the Team Form Provide names, emails, and organization details. This ensures proper access and personalized onboarding. 4️⃣ Membership Activation Our team manually reviews and activates all seats. Activation takes 3–10 business days . You’ll be notified once access is live. 💡 Need to add members later? We’ll help you update your team anytime. Apply for Your Team Discount 👇 📢 Limited-time offer – don’t miss out! First name* Last name* Email* Company name* Company Website* Names & Emails of Each Team Member (minimum 5)* Team Size* Annual Premium Team access. Minimum five seats. Priced per person per year. $2,249.25 Order Now 💡 Have questions? Contact us at Hello@DGPCR.org Terry’s Pharmacology Corner — Created by Dr. Terry Kenakin , powered by Dr. GPCR . Stay connected on LinkedIn and YouTube . Explore : Foundational Lessons — Build Your Pharmacology Core Emerging Drug Hunter — Expand Your Edge Expert-Level Mastery — Advanced Pharmacology Live AMA Sessions with Terry

Your One-Stop-Shop for GPCR Drug Discovery and Development Researchers developing GPCR-targeted therapeutics need a reliable, comprehensive partner that spans discovery, optimization, and regulatory submission. Eurofins DiscoverX leads GPCR research innovation with 25+ years of expertise and provides you with product solutions including cell-based assays for basic research through therapeutic discovery and development. The assays are validated and accepted by industry and the scientific community, with thousands of peer-reviewed publications and billions of data points screened. These industry-standard assays, designed for regulatory submissions, are backed by partnerships with leading pharma and biotech companies worldwide. 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This multi-dimensional characterization extends across our full obesity and diabetes product portfolio, including GIPR, GCGR, AMY receptors, MC4R, and beyond. Access GPCR Obesity and Diabetes Solutions and Key Resources Discover GPCR Obesity and Diabetes Product Solutions Find Your Solution Review GIP Product Solutions to Support Obesity/Diabetes View GIP Solutions Explore GLP-1 Product Solutions to Support Obesity/Diabetes See GLP-1 Solutions Accelerating Obesity Therapeutics Development Download App Note Beyond Eurofins DiscoverX Products: The Full Power of Eurofins Discovery Eurofins DiscoverX cell lines, assays, kits, and custom product solutions represent the foundation of tools for GPCR research and drug discovery and development. When these product solutions are combined with Calixar GPCR membrane proteins and Eurofins Discovery GPCR services, the benefits from integration provide the most comprehensive GPCR research and drug discovery platform spanning the entire discovery and development continuum. Eurofins Discovery GPCR services provides the industry's most extensive collection of validated GPCR assays with hundreds of binding and functional assays, available individually or in panels. These assays use the same platform as the Eurofins DiscoverX assays and beyond. Calixar GPCR membrane proteins , as a service, provides a wide array of GPCRs from various species, purified to the highest standards to ensure purity, integrity, and biological activity. These GPCRs are excellent for use in functional, structural, or identification assays. Let us Help You Get Started! Contact us Visit GPCR Product Solutions

Join the Dr. GPCR Podcast community and shape our next season! Take our quick 5-minute audience survey to help us tailor our content to your needs. Your input matters in delivering exciting and informative episodes. Thank you for being part of our journey and for tuning in! Dr. GPCR Podcast Audience Survey Thanks for listening to this podcast episode Follow us on your favorite Podcast Player Be our Guest Listen and subscribe where you get your podcasts

Join us as a featured guest on the Dr. GPCR Podcast! Explore the fascinating career journeys, groundbreaking discoveries, and impactful contributions of experts in GPCR biology. Share your insights and be part of the conversation. Complete the form below to become a guest - we'll reach out within 48 hours. Don't miss this opportunity to showcase your expertise! Be Our Guest – Dr. GPCR Podcast Share Your Research. Inspire the GPCR Community. Every episode of the Dr. GPCR Podcast features leading scientists, innovators, and biotech professionals whose work is advancing the understanding of G Protein-Coupled Receptors (GPCRs). We discuss breakthrough discoveries, career paths in pharmacology and molecular biology, and how each guest’s research contributes to the global GPCR ecosystem. If you’re working on exciting GPCR-related research — from structural biology to drug discovery — we’d love to feature your story. Fill out the form below and our team will contact you within 48 hours. Fill out this form Frequently asked questions About the Dr.GPCR Podcast At the high of the pandemic, I created the Dr. GPCR Podcast (https://www.ecosystem.drgpcr.com/dr-gpcr-podcast)with three major goals in mind: 1. Share the latest scientific discoveries in the GPCR field through discussions with experts 2. Provide researchers with a different outlet to make their work known and 3. Inspire young scientists to work on GPCRs It’s been a privilege to chat with so many GPCR scientists since 2020. Dr. GPCR’s mission is to bring together the GPCR community from all corners of the world to connect, exchange, and collaborate to improve human health through a better understanding of GPCR biology. So far we have recorded and released over 156 episodes and hosted GPCR specialists from all over the world, includingDr. Bryan Roth,(https://www.ecosystem.drgpcr.com/dr-gpcr-videocast/ep-14-with-dr.-bryan-roth) Dr. Robert Lefkowitz,(https://www.ecosystem.drgpcr.com/dr-gpcr-videocast/ep-27-with-dr.-robert-j.-lefkowit) Dr. Fiona Marshall,(http://www.drgpcr.com/episode-19-from-a-lecture-on-adrenaline-function-to-becoming-a-successful-industry-leader/?utm_source=hs_email&utm_medium=email&_hsenc=p2ANqtz--ksJD7haRDunnferiNnhNIJYWnGvPjZd7Hmva0AOow0hNQKUwTvuanEFpoetCNBMNXmV0U) Dr. Sam Hoare,(http://www.drgpcr.com/episode-37-with-dr-samuel-hoare/?utm_source=hs_email&utm_medium=email&_hsenc=p2ANqtz--ksJD7haRDunnferiNnhNIJYWnGvPjZd7Hmva0AOow0hNQKUwTvuanEFpoetCNBMNXmV0U) Dr. Graciela Pineyro,(http://www.drgpcr.com/podcast-episode-4-dr-graciela-pineyro/?utm_source=hs_email&utm_medium=email&_hsenc=p2ANqtz--ksJD7haRDunnferiNnhNIJYWnGvPjZd7Hmva0AOow0hNQKUwTvuanEFpoetCNBMNXmV0U) Dr. Debbie Hay,(http://www.drgpcr.com/episode-26-dr.-debbie-hay/?utm_source=hs_email&utm_medium=email&_hsenc=p2ANqtz--ksJD7haRDunnferiNnhNIJYWnGvPjZd7Hmva0AOow0hNQKUwTvuanEFpoetCNBMNXmV0U) Dr. Randy Hall,(http://www.drgpcr.com/episode-42-with-dr-randy-hall/?utm_source=hs_email&utm_medium=email&_hsenc=p2ANqtz--ksJD7haRDunnferiNnhNIJYWnGvPjZd7Hmva0AOow0hNQKUwTvuanEFpoetCNBMNXmV0U) tributes toDr. Marc Caronw(https://www.ecosystem.drgpcr.com/dr-gpcr-videocast/ep-100-with-dr-caron-tribute-part-1)ith over 30 guests includingDr. Kathleen Caron,(https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-103-with-dr-kathleen-caron) Dr. Brian Kobilka,(https://www.ecosystem.drgpcr.com/dr-gpcr-videocast/ep-100-with-dr-caron-tribute-part-1) and many other amazing scientists. What is the format of the Dr.GPCR Podcast? Our podcast typically follows an interview-style format. We aim to have engaging conversations about you as a scientist, your career, your work, and anything related to GPCRs to provide valuable insights for our listeners. How long will the podcast recording take? The duration of the podcast recording may vary depending on the episode's topic and the flow of the conversation. On average, recordings usually take around 1 hour. We strive to keep the conversation focused and efficient while allowing enough time for in-depth discussions. How do I book the meeting on Calendly? In the invitation we provided a booking link.(https://calendly.com/drgpcr/podcast) When clicking the link you’ll see a calendar, pick any date, and the schedule options will pop up. Then you will be asked to leave your name and email for future automated messages around our meeting. Can I reschedule or cancel our meeting? Yes, you can reschedule or cancel our meeting through Calendly. What should I expect during the recording process? Before we hit record, we will have a few minutes to discuss any questions or concerns and give you time to get comfortable. • During the recording process, we will begin by introducing the episode and presenting you as our guest. • We'll then engage in a conversation centered around your career and how you got introduced to GPCRs. Feel free to share your thoughts, experiences, and insights openly. If there are specific questions or talking points we plan to cover, we'll provide them in advance to help you prepare. • We aim to ensure you have a great time and give a sneak peek at who you are as a scientist to the GPCR community. How should I prepare for the podcast recording? We always send our guests a Podcast Episode Outline,(https://docs.google.com/document/d/1klENp4q_B1yUyDv9eJYylESws996V9U-ou10pAQfWfI/edit) which includes all the questions we typically ask during the recording. You can take some time to gather your thoughts around these key points. These questions just serve as a guide, and we don’t have to go through all of them. Think of our chat as a casual discussion at an in-person conference where we are meeting for the first time. Sometimes we don’t follow the questions outlined because the discussion takes us to an also relevant and interesting conversation. We want to make sure that you are comfortable and we will never ask questions that would make you uncomfortable. Do I need to bring any equipment for the recording? In most cases, you won't need to bring any equipment for the recording as computers usually have all the necessary equipment integrated. If you do have an external microphone or webcam you’d like to use, it will make a difference, just make sure they are connected and working properly before going into the meeting. How do I join the recording session? All recordings are conducted via Zoom. Please ensure you test your Zoom setup before the meeting to avoid any technical issues. Are there any features you’d recommend to use? Recordings are done on Zoom. Touch-up- my appearance. Adjust for low light. We encourage you to have a headset with a good microphone. We also encourage you to be sitting in front of a window or in front of a sort of light so that your entire face can be seen in the recording. Please note that we do record audio and video. Can I promote my work or projects during the podcast? Absolutely! We encourage our guests to share information about their work, projects, or any relevant initiatives they are involved in. Our podcast is a great platform for you to showcase your expertise and connect with the GPCR community. Please feel free to mention and discuss your work during the conversation. Will there be an opportunity for me to ask questions or clarify any points? Yes, we value the interactive nature of our podcast and welcome your questions or requests for clarification. If you'd like to ask anything or any points you'd like to clarify before, during, or after the recording, please don't hesitate to speak up. We want to ensure that the discussion is engaging and informative for both our guests and our community. How will the podcast episode be promoted? Once the episode is recorded and edited*, we will promote it through various channels, including our website, multiple podcast streaming platforms, social media platforms, and email newsletters. We encourage you to share the episode with your audience as well. Together, we can maximize the episode's reach and impact. *Note that by editing, we mean removing any interruptions, or background noises, from the recording. We will not edit what you say unless you ask us to remove or add sections, sometimes we can re-record. When can I expect my podcast episode to be released? Your podcast episode will be released based on our production schedule and the order of episodes in the queue. We aim to provide an estimated release date after recording. Typically, episodes are released 4-6 weeks after recording. We'll notify you once it's live so you can share it with your network. Note that this timeline may vary if we take a break from releasing episodes, usually between December 15 and January 15. Can I listen to the episode after it’s been recorded? If you would like to listen to the episode after being recorded, we are more than happy to send it to you for your review. That being said, if there’s anything you’d like us to edit, feel free to reach out so we can work on it before it gets published. Can I watch the video podcast after it’s been published? The podcast video recordings are only available for the Premium Members on our Ecosystem. Anyone with a Free website membership or with an account on the different streaming platforms will have access to the podcast version only. How can I stay updated on future episodes or collaborate again in the future? To stay updated on future episodes and potential collaboration opportunities, we recommend subscribing to our podcast on your preferred platform. If you are interested in collaborating again, you can always fill out this form (https://docs.google.com/forms/d/1q3IKapHBHgBA21R7vjZV8Fs48GgGjmNUNK5VvsweXK0/edit)again and/or write to any of the following emails: hello@drgpcr.com(mailto:hello@drgpcr.com) I am still an undergraduate, Ph.D. student, or a post-doc, am I welcome to join as a guest? Yes, we value what anyone in the GPCR field has to say. For Dr.GPCR you are an expert in your own project, and we highly encourage you to accept our invitation to participate in the Podcast. Don’t hesitate to reach out to us if you’d like to recommend a colleague as a guest. Do you have any suggestions in terms of podcast equipment? Yes, here’s a list of accessible items we recommend for podcast creators: Video conference Lighting Kit(https://www.amazon.com/gp/product/B09D387Y4D/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&th=1) Wireless microphone(https://www.amazon.com/EJCC-Microphone-Microphones-Recording-Interview/dp/B0BP7NNKBJ/ref=sr_1_22?keywords=podcast%2Bmicrophone&qid=1691759863&s=electronics&sr=1-22&th=1) Any tips on achieving good lighting for the video podcast recording? Good lighting is key for any type of video. Here are some easy tips: • Sitting in front of a window is always the best option for good lighting on any type of video. • If we are recording at night or you don’t have natural light in your usual space, you can always use a desk lamp and put it next to the computer. • The front light is always more flattering than the top light, which is what we usually have in house spaces. If you want to go like a pro, you can turn on a front light, and a backlight, that way you won’t look plain on camera. Listen and subscribe where you get your podcasts

Home Courses Articles About Log In / Sign Up Terry's Pharmacology Corner Lost in GPCR Complexity? Step Into Terry’s Corner Finally, See the Signal 🔥 Watch the AMA Session | Feb 2, 2026 🔥 Watch course | Dec 9, 2025 🔥 Watch course | Nov 11, 2025 🔥 Watch course | Oct 14, 2025 🔥 Watch course | Sept 23, 2025 🔥 Watch course | Sept 2, 2025 🔥 Watch course | Aug 12, 2025 🔥 Watch course | July 22, 2025 🔥 Watch course | July 1, 2025 🔥 Watch course | July 1, 2025 🔥 Watch course | Feb 10, 2026 🔥 Watch the AMA Session | Dec 2, 2025 🔥 Watch the AMA Session | Sept 18, 2025 🔥 Watch course | Oct 7, 2025 🔥 Watch course | Sept 16, 2025 🔥 Watch course | Aug 26, 2025 🔥 Watch course | Aug 5, 2025 🔥 Watch course | July 15, 2025 🔥 Watch course | July 1, 2025 🔥 Watch course | July 1, 2025 🔥 Watch course | Feb 3, 2026 🔥 Watch course | Nov 18, 2025 🔥 Watch course | Oct 21, 2025 🔥 Watch course | Sept 30, 2025 🔥 Watch course | Sept 9, 2025 🔥 Watch course | Aug 19, 2025 🔥 Watch course | July 29, 2025 🔥 Watch course | July 8, 2025 🔥 Watch course | July 1, 2025 🔥 Watch course | July 1, 2025 1 2 1 ... 1 2 ... 2 TCBuyCourse Start Learning with Terry 🔥 Upgrade to Premium Terry’s Corner $2,999 $ 2,999 Every year 40 years. One corner. One pricing. Valid until canceled 7 day free trial Select Watch 4 New Courses Each Month Connect in a Private Drug Hunter Hub Skip The Fluff, Learn What Matters Join Monthly AMAs with Terry Unlock 40+ Years of Expertise Master GPCRs with Precision Premium Yearly for Teams $2,249.25 • per year • per person • 25% discount • minimum 5 seats How does it work? 1️⃣ Gather Your Team 2️⃣ Submit Your Team Details 3️⃣ Complete the Payment 4️⃣ Activate Memberships Select Terry’s Pharmacology Corner — Created by Dr. Terry Kenakin , powered by Dr. GPCR . Stay connected on LinkedIn and YouTube . Explore : Foundational Lessons — Build Your Pharmacology Core Emerging Drug Hunter — Expand Your Edge Expert-Level Mastery — Advanced Pharmacology Live AMA Sessions with Terry

Join the Dr. GPCR Affiliate Program and earn commissions by helping connect the global GPCR community. Share our ecosystem, courses, and events to advance drug discovery together. Dr. GPCR Affiliate Program Earn by Empowering the GPCR Ecosystem Help us connect scientists, founders, and innovators while earning commissions for every member, partner, or course you bring into the Dr. GPCR community. Become our Brand Ambassador Our vision is to build the best platform for the GPCR community and help you the scientists and business owners to share their experiences with others, get help, and find the perfect tools, colleagues, build their strategy and advance our field. As an ambassador, with the Affiliate Program, you'll earn a commission whenever your referral link is used and a qualified purchase has been made by your friends, colleagues, or followers who are also part of the GPCR field. Become our Brand Ambassador About Dr. GPCR Ecosystem We aspire to provide opportunities to connect, grow, and thrive together as a dynamic group. The goal is to better understand and exploit the druggability of GPCRs, together. The Dr. GPCR Ecosystem members have the opportunity to solve problems, find answers to their questions, identify the perfect service provider, and, most importantly, boost their GPCR project with just a few clicks. The Ecosystem is designed for all GPCR professionals to have an affordable and highly effective way to showcase their knowledge, connect, and advance the field, together. About the Dr. GPCR brand ambassador affiliate program Who can be a Dr. GPCR ambassador? Scientists and trainees with a strong GPCR background who like and want to create content by writing articles about their favorite GPCR topics and sharing these on social media platforms such as LinkedIn and other options listed at the end of this page. Who is eligible for the Dr. GPCR affiliate program? A GPCR background is mandatory independent of your current position and industry. You also must be an individual Dr. GPCR Ecosystem membership holder. For full details on eligibility, please read our Affiliate Policy . How do I apply for the affiliate program? To become an affiliate, you must create an account here . How does the Dr. GPCR affiliate program work? After becoming a member of the affiliate program, you'll get your personalized link where you can send your potential clients. After every qualified sale, you will earn a commission of $50. How does the commission work? Each qualifying sale earns a commission (excluding sale cancellations). Does it cost me anything to become an affiliate? The program is free to join; there are no monthly charges and no minimum sales requirements. However, the number of ambassador members is limited. Dr. GPCR reserves the right to remove the least active members from the program. Can I invite someone to participate? Yes! You can invite anyone to participate, and we welcome anyone if they are qualified. Do I need to sign a contract? There's no contract to sign when joining our program. You will be required to agree to our Terms and Conditions and our Affiliates Policy when you sign up on Ecosystem.DrGPCR.com. You can leave the program at any time by contacting us. Dr. GPCR may also remove affiliates from the program at any time. Is there an exclusivity agreement when joining? There's no exclusivity agreement. You can take part in other affiliate programs as well as be part of ours. Are affiliates outside of the U.S. eligible for the Affiliate Program? Yes, you may join the affiliate program as long as you have a verified PayPal account. What type of channels, tools, and techniques can I use to promote Dr. GPCR Ecosystem? OK to use: - Writing, blogging, guest blogging, - Podcast, video, vlog - Social media sharing, - YouTube & TikTok channels, - Business Page and website, - Informational and fan sharing, - Presentations and meetups. Not OK to use: Advertising Spam Anything misleading or annoying Social media bios Paying or offering intensives for the use of your link How do I track my earning? We use a third-party provider, GoAffPro.com , where you'll create your own account and through your dashboard, you can track all your activities. When will I receive my affiliate commissions? Affiliate payments are processed and sent directly to your PayPal in 7 to 30 days. We could hold payments up to 30 days to allow for processing, chargebacks, etc. Good Faith We introduce programs such as the Dr. GPCR Ambassador, in good faith and expect the same good faith in return. Please note that we may withhold awards where we believe customers are acting in bad faith or otherwise acting contrary to the intent of this program. To be clear, commercializing, advertising, publishing, mass distributing, selling, or paying for the use of referral links is not appropriate, and we will not honor such links. We cannot cover every nefarious scenario, nor will we attempt to, but we do promise to be fair and reasonable. Closure We are so excited about the Dr. GPCR Ambassador program. It will be a remarkable journey and fun to build together the "next-generation" platform for the B2B industry. With your help, we can create a world where the living experience is joyful and worry-free. Are you ready? Sign up , explore, and connect with us. Become our Brand Ambassador

Turn GPCR discovery chaos into clarity—Yamina’s Corner offers expert GPCR strategy, CRO guidance, and tailored scientific support to accelerate your pipeline. Home About News Get in Touch Welcome Turn GPCR Chaos Into Insights Expert strategic and scientific consultancy to accelerate your pipeline Book My Consultation Critical Bottlenecks in Your GPCR Pipeline ❌ Overwhelming pharmacology Data ❌ Suboptimal CRO Partnerships ❌ Stalled Pipeline Progression ❌ Uncertainty in GPCR Investments Advisory Focus Areas Expert support for Biotech innovators, VC investors and CRO partners Biotech Pipeline Acceleration For Biotech Leaders & Scientists Actionable Data Insights: Translate complex GPCR pharmacology into clear decisions for lead optimization and candidate selection. Accelerated Program Progression: Design robust assay cascades and establish key go/no-go points to speed up your pipeline. Optimized CRO Collaboration: Streamline internal R&D and external CRO workflows to prevent delays and ensure preclinical success. Fuel Discovery VC Due Diligence & De-risking For Venture Capital Firms De-risk GPCR Investments: Identify critical scientific red flags and technical gaps in GPCR assets before committing capital. Actionable Scientific Validation: Ensure target companies execute the right GPCR pharmacology experiments to generate robust, decision-making data. Clear Platform Assessment: Gain rapid, independent insight into GPCR platform risks and true therapeutic potential to inform investment strategy. Fast-Track Discovery CRO Partnership & Optimization For Contract Research Organizations Elevate Scientific Offerings: Refine and optimize your GPCR assay platforms and in vitro models to deliver superior data quality and results. Enhance Client Project Delivery: Streamline workflows and improve scientific execution to increase client satisfaction and secure repeat business. Differentiate Your Market Position: Showcase your specialized GPCR expertise to stand out from competitors and attract high-value biotech and pharma partners. Power Discovery How We Work: Your Path to GPCR Success 1 Initial Strategic Alignment We begin with a focused discussion of your current GPCR program and critical challenges, identifying precise areas for collaboration. 2 Define Actionable Objectives Together, we clarify specific, measurable goals, from target validation and assay development to CRO selection or portfolio strategy, ensuring a tailored approach. 3 Collaborative Execution & Impact I integrate directly into your discovery process to remove roadblocks, enhance execution, and generate actionable scientific data, driving confident decisions and sustained preclinical progress. Advance My Discovery My Approach: Precision Guidance for GPCR Programs I provide the focused, scientific expertise that accelerates complex GPCR discovery programs, ensuring clarity and de-risking your path from target to candidate. I integrate seamlessly with biotech, VC, and CRO teams as a trusted, objective partner. Integrated Strategic Partnership We collaborate directly with your scientific and leadership teams. This partnership prevents bottlenecks and optimizes resource allocation, ensuring every strategic decision efficiently propels your program forward and aligns with critical business objectives. Biology-First, Data-Driven Solutions Every recommendation is rooted in GPCR biology, pharmacology experience. This provides evidence-based strategies leveraging deep GPCR expertise to overcome specific scientific challenges and maximize your program's potential. Accelerated Preclinical Progression I streamline critical operational processes, from advanced assay design and CRO management to rapid go/no-go decision-making. This focused execution accelerates preclinical milestones and maximizes the efficiency and return on your R&D investment. Core Values: The Foundation of Every Successful Partnership My advisory is built on principles that ensure clarity, minimize risk, and drive enduring results in GPCR drug discovery. Scientific Integrity Every recommendation is rigorously evidence-based, not reliant on assumptions. This ensures robust, defensible decisions that de-risk your program from early discovery to regulatory milestones. Operational Discipline I instill structure and consistency across every phase of your discovery process. This approach eliminates inefficiencies and standardizes workflows, accelerating your path to a preclinical candidate. Collaborative Partnership I operate as an embedded, invested partner with your team. Your program's success is my priority, fostering a transparent, results-driven environment that maximizes collective expertise and accelerates progress. About Yamina A. Berchiche I'm Yamina A. Berchiche, and I understand the intricate challenges of GPCR drug discovery. Small missteps can derail entire programs: underperforming assays, off-track CROs, and data that fails to drive decisions. That's precisely where my expertise becomes your strategic advantage. With over two decades dedicated to GPCR pharmacology across biotech, academia, and the non-profit sector, I bring unparalleled scientific depth and operational precision to every project. My work focuses on integrating directly with your team as a strategic partner. Whether it's optimizing CRO selection, building robust internal capabilities, or translating complex data into decisive program advancements, I help you eliminate friction, align efforts, and accelerate your path to success. As the founder of Dr. GPCR, I also offer a unique, broad perspective and trusted relationships within the field. This allows me to connect you with critical insights and key collaborators, further accelerating your progress in GPCR drug discovery. Let's Talk Discovery What Partners Say Here’s what it’s like to work together — from people I’ve supported on both sides of the bench. Anne Marie Quinn, CEO Montana Molecular As a CRO, we were delivering high-quality data across complex biotech programs, but translating that data into aligned, timely decisions across stakeholders wasn’t always straightforward. After partnering with her, communication became clearer, deliverables were better defined, and collaboration across teams ran more smoothly. She helped streamline complex projects and made the CRO–client relationship more effective and productive. Terry Kenakin, PhD UNC Chappel Hill In complex pharmacological discovery programs, scientific ambiguity and fragmented execution can quietly erode progress. Yamina brings the clarity, rigor, and structured decision-making that keeps programs on track. Across multiple discovery efforts, she established clear decision gates and alignment across teams, materially strengthening candidate progression and prioritization. Her involvement consistently elevates both the scientific discipline and the quality of portfolio-level decisions. Murat Tunaboylu, CEO Antiverse Before engaging Yamina, our team faced hurdles navigating complex early discovery decisions. We had critical program choices ahead and needed clearer direction. Bringing her in marked a meaningful shift. We made confident progress on a pivotal program and gained clarity on our next strategic focus. Yamina was instrumental in unifying our scientific and operational teams, strengthening alignment and driving momentum across execution. Abishek Iyer, CEO Ashta Therapeutics Before working with Yamina, we had solid internal momentum but needed to better align our biology, assay priorities, and compound strategy into a cohesive, decision-driven plan. Her input helped us structure the screening funnel, define clear go/no-go criteria, and integrate ADME and mechanistic assays in a way that reflected both biological rationale and operational realities. She has been a true thought partner — not only on tactical execution, but on pressure-testing hypotheses, challenging assumptions, and maintaining disciplined forward progress. Book Book My 30 Minutes Strategy Call Menu Home Services About News Ready to collaborate? Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution across biotech, VC, and CRO teams. 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