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CINVESTAV, Mexico City, Mexico October 23-25

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Full Agenda

Adhesion GPCR workshop 2024

CINVESTAV, Mexico City, Mexico
October 23-25

Oct 23 - 9:00 AM

Registration & Welcoming Remarks

10:00 AM

Student Flash Presentations

Health and Disease, Metabolism, Nervous System, Proteomics and Transcriptomics, Receptor Structure, Signaling and Activation Mechanism

Abhishek Kumar Singh · Alex Torrelli-Diljohn · Emmanouil Kyrloglou · Vasiliki Karagiannakou · Lara-Sophie Brodmerkel · Rashed Rezwan Parag · Hailey Steichen · Tyler Bernadyn · Jesse Stillwell

12:00 PM

Coffee Break with lights snacks

12:30 PM

State of the Art Talk

Adhesion GPCR in Mechanobiology

Nicole Scholz

1:00 PM

Plenary Lecture

Identification and Functional Characterization of Adhesion GPCRs As Steroid Hormone Receptors and Hearing and Balance Receptors

Jinpeng Sun

2:00 PM

Complimentary Lunch

3:00 PM

Session I

Tethered agonist - dependent/independent activation mechanism in AGPCRs

Signe Mathiasen · Demet Araç · Yan Zhang · Andrew Dates · Frank Kwarcinski · Peng Xiao

5:00 PM

Leaving for City Center

5:30 PM

Mexico City Nocturnal Tour, Food and drinks

Oct 24 - 9:00 AM

Session II

AGPCR signaling pathways and trafficking

Yuling Feng · Monserrat Avila Zozaya · Erwin G. Van Meir · Pal Kasturi

10:30 AM

Coffee Break with lights snacks

11:00 AM

Session III

Molecular tools and biosensors directed at AGPCR signaling and function

Stephanie Häfner · Laurent Sabbagh · Ana Lilia Moreno Salinas

12:00 PM

Session IV

AGPCRs signaling in the nervous system

Joseph Duman · Simeon R. Mihaylov · Anne Bormann

1:00 PM

Complimentary Lunch

2:00 PM

Posters

Caroline Formstone · Jianxiang Xue · Virginea de Araujo Farias · Anne Bormann · Szymon P. Kordon · Tingzhen Shen · Bill Huang · Júlia Rosell · Tobias Langenhan · Mao Chunyou  Â· Mariam Melkumyan

3:00 PM

Session V

Structural mechanisms of AGPCR signaling and function

Fabian Pohl · Sumit Bandekar · Florian Seufert

4:00 PM

Dr. GPCR Community Presentation

Monserrat Avila Zozaya

4:30 PM

Board meeting/General assembly

Welcome to Join

5:30 PM

Leave for dinner reception

6:00 PM

Complimentary Reception dinner

Oct 25 - 9:00 AM

Session VI

AGPCRs shaping the nervous system

Yimin Zou · Dimitris Placantonakis

10:00 AM

Coffee Break with lights snacks

10:30 AM

Session VII

Physiological and pathological roles of AGPCRs in the nervous system

Nicole Perry-Hauser · Mariam Melkumyan · Beatriz Blanco Redondo · Willem Berend Post

12:30 PM

Complimentary Lunch

1:30 PM

Session VIII

Physiological and pathological roles of AGPCRs in the periphery

Tobias Langenhan · Anastasia Georgiadi · Douglas Tilley · Hee-Yong Kim · Alain Garcia De Las Bayonas · Gabriela Aust

3:30 PM

Coffee Break with pastries annoucement of the aGEM award

4:00 PM

Session IX

4:40 PM

Closing remarks

5:00 PM

Departure

Abhishek Kumar Singh

Abhishek Kumar Singh

Adgrg6/Gpr126 is Required for Myocardial Notch Activity and N-cadherin Localization to Attain Trabecular Identity

Rashed Rezwan Parag

Rashed Rezwan Parag

Novel isoforms of adhesion G protein coupled receptor B1 (ADGRB1/BAI1) generated from an alternative promoter in intron 17

Jinpeng Sun

Jinpeng Sun

Identification and Functional Characterization of Adhesion GPCRs As Steroid Hormone Receptors and Hearing and Balance Receptors

Frank Kwarcinski

Frank Kwarcinski

Discriminating between the extracellular scaffolding and G protein signaling roles of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse, H381S

Pal Kasturi

Pal Kasturi

Site Specific N-Glycosylation Of The N-Terminal Fragment Of ADGRG6 Drives Proteolytic Processing, Trafficking And Signalling

Simeon R. Mihaylov

Simeon R. Mihaylov

Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase TNIK

Yimin Zou

Yimin Zou

ADGRCs in glutamatergic synapse formation, maintenance and degeneration

Willem Berend Post

Willem Berend Post

The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation

Alain Garcia De Las Bayonas

Alain Garcia De Las Bayonas

The Adhesion GPCR Cupidon Regulates Mating In The Closest Relatives Of Animals

Alex Torrelli-Diljohn

Alex Torrelli-Diljohn

Investigating The Role of ADGRB3 Loss of Expression in Brain Tumor Formation in Li-Fraumeni Syndrome

Hailey Steichen

Hailey Steichen

Identification of Differentially Expressed Gpr116 (Adgrf5) Transcript Variants in Mouse Kidney

Signe Mathiasen

Signe Mathiasen

Signaling Properties of ADGRL3

Peng Xiao

Peng Xiao

Tethered Peptide Activation Mechanism of Adhesion GPCRs

Stephanie Häfner

Stephanie Häfner

The NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs

Anne Bormann

Anne Bormann

Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl

Dimitris Placantonakis

Dimitris Placantonakis

Antibody-drug conjugates targeting CD97 in glioblastoma

Tobias Langenhan

Tobias Langenhan

The CELSR/ADGRC Homolog Flamingo Is Not Autoproteolytically Processed By The GAIN Domain

Gabriela Aust

Gabriela Aust

Critical role for CD97/ADGRE5 in the induction of allergic airway inflammation

Emmanouil Kyrloglou

Emmanouil Kyrloglou

GPR124 Mediates Adhesion Of Leukemic Stem Cells To Their Niche And Leads To Myeloid Skewing

Tyler Bernadyn

Tyler Bernadyn

Elucidating The Role Of GPR97/ADGRG3 In Neutrophil Biology

Demet Araç

Demet Araç

An ECR-Mediated and TA-independent Mechanism of aGPCR Activation: Direct Communication of Extracellular Region with Transmembrane Domain in a Holo-Adhesion GPCR

Yuling Feng

Yuling Feng

Localization of putative ligands for adhesion G protein-coupled receptors in mouse tissues.

Laurent Sabbagh

Laurent Sabbagh

bioSens-All: A Multiparametric BRET-Based Platform for Comprehensive Profiling of adhesion GPCR Signaling and Pharmacology-Enabling Drug Discovery

Fabian Pohl

Fabian Pohl

Structural Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G Protein-Coupled Receptors

Nicole Perry-Hauser

Nicole Perry-Hauser

Adhesion G protein-coupled receptor latrophilin-3 (ADGRL3) modulation of dopaminergic neurotransmission

Anastasia Georgiadi

Anastasia Georgiadi

Adhesion GPCR GPR116/Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications for adaptive thermogenesis during prolonged cold exposure

Vasiliki Karagiannakou

Vasiliki Karagiannakou

A single cell GPCR map of thermogenic fat

Jesse Stillwell

Jesse Stillwell

Next Generation MBD2 inhibitors for Brain Cancer Therapy

Yan Zhang

Yan Zhang

Structural Insights into the Activation Mechanisms of Adhesion GPCRs

Monserrat Avila Zozaya

Monserrat Avila Zozaya

The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial cell identity and function

Ana Lilia Moreno Salinas

Ana Lilia Moreno Salinas

Characterizing hADGRE5/CD97 Activation and Signaling: A Mechanical Stimulation BRET-Based Approach (MS-BRET)

Sumit Bandekar

Sumit Bandekar

Structural studies of the CELSR1 extracellular region reveal a compact multidomain module of fourteen domains which regulates signaling

Mariam Melkumyan

Mariam Melkumyan

GPR110 modulates anxiety-like behaviors and memory function in mice potentially through neuronal and neuroimmune alterations during neurodevelopment

Douglas Tilley

Douglas Tilley

ADGRF5-mediated regulation of cardiac health and disease

Lara-Sophie Brodmerkel

Lara-Sophie Brodmerkel

GAIN Domain Dynamics And Its Relevance For Adhesion GPCR Signaling In Vivo

Nicole Scholz

Nicole Scholz

Adhesion GPCR in Mechanobiology

Andrew Dates

Andrew Dates

Heterogeneity of Tethered Agonist Signaling in Adhesion G Protein-Coupled Receptors

Erwin G. Van Meir

Erwin G. Van Meir

Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, increase radiosensitivity and augment survival in medulloblastoma.

Joseph Duman

Joseph Duman

BAI1/ADGRB1-mediated Regulation of Mitochondrial Morphology in Axons

Florian Seufert

Florian Seufert

Unveiling the GPS Cleavage Mechanism in ADGRL1 with QM/MM

Beatriz Blanco Redondo

Beatriz Blanco Redondo

Uncovering the signaling pathway of the ADGRA homolog Remoulade in Drosophila

Hee-Yong Kim

Hee-Yong Kim

Characterization of Phenotypes Associated with GPR110 Deletion

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