Search Results
Results found for "GPCR Drug Design"
- 220 GPCRs. One platform. Endless questions. In Ep.167 of the Dr. GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex, dual-tagged constructs, and open science. Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCR #GPCRpodcast #GPCRtools #OpenScience | Dr. GPCR Ecosystem
GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs. GPCR Podcast 220 GPCRs. One platform. Endless questions. In Ep.167 of the Dr. GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs.
- Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! Cutting-edge cryo-EM reveals how LYCHOS, a lysosomal protein, senses cholesterol to regulate metabolism and cell growth ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/cryo-em-reveals-cholesterol-binding-in-the-lysosomal-gpcr-like-protein-lychos #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → Check out the latest GPCR news in the Ecosystem today! metabolism and cell growth ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function /cryo-em-reveals-cholesterol-binding-in-the-lysosomal-gpcr-like-protein-lychos #gpcr #drgpcr Published on February 4, 2025 Category GPCR Weekly News Check out the latest GPCR news in the Ecosystem today! /cryo-em-reveals-cholesterol-binding-in-the-lysosomal-gpcr-like-protein-lychos #gpcr #drgpcr Previous
- Dr. G. Aditya Kumar | Dr. GPCR Ecosystem
role of the membrane microenvironment in the subcellular organization, trafficking, and signaling of GPCRs He currently uses high-resolution fluorescence microscopy and biochemistry to study GPCR trafficking and membrane biology to better understand how the dynamic receptor microenvironment contributes to GPCR GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Gregory Tall | Dr. GPCR Ecosystem
family or Family B2 GPCRs. We found that adhesion GPCRs are activated by a tethered peptide agonist mechanism that differed from Adhesion GPCRs pre-cleave themselves and the two resultant fragments of the receptor remain together goals are to explore this mechanism in detail and to understand how it may happen for the 33 adhesion GPCRs GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.
- Dr. Evi Kostenis | Dr. GPCR Ecosystem
Research interests: Signaling mechanisms involving GPCRs and heterotrimeric G proteins" Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Jean-Philippe Pin | Dr. GPCR Ecosystem
His studies led to new concepts in the GPCR field, such as the activation of cell surface receptors by intracellular proteins; the regulation of GPCRs by both negative and positive allosteric modulators, and the asymmetric functioning of GPCR dimers. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Mark Schmeizl | Dr. GPCR Ecosystem
GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Martin Audet | Dr. GPCR Ecosystem
GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Lukas Grätz | Dr. GPCR Ecosystem
My initial focus was on creating an automated chimeric homology modeling pipeline for GPCRs and since have branched out to multiple areas of GPCR research such as sequence alignments, generic numbering GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Sudha Shenoy | Dr. GPCR Ecosystem
laboratory has continued to work on identifying the molecular mechanisms that ascribe ubiquitin code on GPCRs Current efforts aim to understand the regulation of GPCR and beta-arrestin signaling in the heart and GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Gáspár Pándy-Szekeres | Dr. GPCR Ecosystem
My initial focus was on creating an automated chimeric homology modeling pipeline for GPCRs and since have branched out to multiple areas of GPCR research such as sequence alignments, generic numbering GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Masha Niv | Dr. GPCR Ecosystem
Her work focuses on both sweet and bitter taste receptor GPCRs and her lab established the BitterDB . GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Matthew Eddy | Dr. GPCR Ecosystem
Eddy began learning and investigating human GPCRs while training in the laboratories of Professors Raymond GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Nicolas Gilles | Dr. GPCR Ecosystem
He is pioneering the investigation of animal toxins acting on GPCRs, the largest therapeutic target class GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Qing Fan | Dr. GPCR Ecosystem
Qing is a structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Randy Hall | Dr. GPCR Ecosystem
lab has published numerous groundbreaking findings shedding light on the signaling and regulation of GPCRs Randy’s lab has a special interest in studying disease-associated mutations to human GPCRs that perturb Join me to learn more about Randy’s work, hear his insights on the GPCR field, and also hear the story GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Complimentary Lunch | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Welcoming Remarks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Closing remarks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Dr. Graham Ladds | Dr. GPCR Ecosystem
This project enabled him to return to his interest in GPCRs. pharmacological investigations and mathematical modeling to study factors that control agonist bias at GPCRs GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. GPCR University is officially back! 🎆 Join Dr. Terry Kenakin for "The Practical Assessment of Signaling Bias" workshop! 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling. ✳️Early Bird discounts for Premium Members! ➡️Register today at https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR University is officially back! 🎆 Join Dr. 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling #drgpcr Published on January 20, 2025 Category GPCR University Dr. GPCR University is officially back! 🎆 Join Dr. uncomfortable truth: 👉 Your biotech is already running on an operating cadence you didn’t consciously design
- Dr. Debbie Hay | Dr. GPCR Ecosystem
Her work is primarily focused on class B GPCRs and their interactions with RAMPs. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Davide Calebiro | Dr. GPCR Ecosystem
, engineers and computer scientists focusing on the basic mechanisms of G protein-coupled receptor (GPCR To study GPCR signalling, they develop and use innovative optical methods based on FRET and single-molecule His major scientific contributions include the discovery that GPCRs are not only active at the plasma GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Biochemical Mechanisms Underlying Location Bias in GPCR Signaling
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Biochemical Mechanisms Underlying Location Bias in GPCR Signaling Date & Time Saturday, November His lab is also interested in identifying novel signal transduction mechanisms of GPCRs, such as the GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- State of the Art Talk | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda State of the Art Talk Adhesion GPCR in Mechanobiology Abstract Only Available
- GPCR activation is well-known to be a multi-step process. However, current molecular structures only capture the fully activated complex. Check out this paper to see how scientists combine different techniques to elucidate the intermediate GPCR-mini-Gαsβγ complex at 2.6 Å. Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structure-and-function-of-a-near-fully-activated-intermediate-gpcr-g%CE%B1%CE%B2%CE%B3-complex #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → GPCR activation is well-known to be a multi-step process. ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structure-and-function-of-a-near-fully-activated-intermediate-gpcr-g %CE%B1%CE%B2%CE%B3-complex #gpcr #drgpcr Published on February 11, 2025 Category GPCR Weekly News GPCR ➡️ https:// www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structure-and-function-of-a-near-fully-activated-intermediate-gpcr-g %CE%B1%CE%B2%CE%B3-complex #gpcr #drgpcr Previous Next Recent Articles
- Dr. Neil Grimsey | Dr. GPCR Ecosystem
Neil Grimsey " During my postdoctoral studies at USCD, I discovered a novel GPCR-dependent atypical kinase GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. John Streicher | Dr. GPCR Ecosystem
His encounter and interest in signaling in the context of GPCRs during his postdoctoral training in Dr GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Graciela Pineyro | Dr. GPCR Ecosystem
Graciela Pineyro’s love for GPCR pharmacology started in Uruguay where she first worked on the serotonin GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Antony A. Boucard Jr | Dr. GPCR Ecosystem
It is then that his interest bloomed for the study of GPCRs while joining the group of Dr. In this institution dear to the heart of GPCR enthusiasts given that its faculty personnel included Dr adhesion molecules which would eventually prompt him to investigate the role of a peculiar family of GPCRs Boucard´s lab focuses on molecular and cellular mechanisms underlying the function of adhesion GPCRs GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.






















