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Results found for "GPCR Drug Design"
- Dr. Timo De Groof | Dr. GPCR Ecosystem
During his Ph.D., he used these nanobodies as research tools, to investigate different GPCR conformations In the near future, Timo hopes to combine his previous GPCR experience with his current focus to set up his own research line focusing on translational applications of GPCR-targeting nanobodies. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Started in medicinal chemistry. Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. A thesis project, a mentor’s advice, and a leap during the pandemic changed everything. Now she’s leading Celtarys, building custom fluorescent probes, and partnering with Dr. GPCR to support assay development worldwide. Meet Celtarys and learn more about its leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarys #GPCRcommunity #DrGPCR #FluorescentLigands #GPCRdrugDiscovery #ScientificLeadership #BiotechInnovation | Dr. GPCR Ecosystem
Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. GPCR to support assay development worldwide. leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast GPCR Podcast Started in medicinal chemistry. Got hooked on ligand design. Dr. GPCR to support assay development worldwide.
- Dr. Paul Insel | Dr. GPCR Ecosystem
GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Katarzyna Marcinkiewicz | Dr. GPCR Ecosystem
GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma Date & She is currently working to understand the signaling and degradation of GPCRs in disease states to help GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 Don’t miss out—update yours now! | Dr. GPCR Ecosystem
Home → Flash News → A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 GPCR Profiles A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 Don’ www.ecosystem.drgpcr.com/account/my-account and meet all the fantastic scientists that are part of our community 😉 #gpcr
- Sri Kosuri | Dr. GPCR Ecosystem
GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Bianca Plouffe | Dr. GPCR Ecosystem
Bioluminescence Resonance Energy Transfer (BRET)-based technology to tackle important questions related to GPCRs Lefkowitz , which led to the finding that both β-arrestin and G protein can simultaneously bind to some GPCRs GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Stuart Maudsley | Dr. GPCR Ecosystem
At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Stuart Maudsley | Dr. GPCR Ecosystem
At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Stuart Maudsley | Dr. GPCR Ecosystem
At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Thank You Page | Dr. GPCR Ecosystem
GPCR Ecosystem! Stay tuned for updates, exclusive content, and exciting opportunities in the world of GPCR research.
- Leave for dinner reception | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Leaving for City Center | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, shedding light on its role in DOR downregulation and endosomal regulation. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/an-engineered-trafficking-biosensor-reveals-a-role-for-dnajc13-in-dor-downregulation #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, Check out the latest GPCR news in the Ecosystem today! #drgpcr Published on March 24, 2025 Category GPCR Weekly News A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, shedding light on its role in DOR downregulation and endosomal Check out the latest GPCR news in the Ecosystem today!
- 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? Ep.165 of the Dr.GPCR Podcast is your finance + operations crash course—delivered by two experts who support early-stage mission-driven teams like Dr. GPCR. 🎧 Smart, practical, and full of real talk: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Home → Flash News → 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? GPCR. 🎧 Smart, practical, and full of real talk: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup Published on May 15, 2025 Category Dr. GPCR Podcast 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? Germain #gpcr #DrGPCR #ScienceStartup Previous Next Recent Articles
- Jacob Lee & Jin Choe | Dr. GPCR Ecosystem
GPCR Ecosystem Jin Choe on LinkedIn Jin Choe on Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Yamina Berchiche | Dr. GPCR Ecosystem
G protein-coupled receptors (GPCRs) mediate a vast variety of critical biological processes and provide GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- In Ep.163 of the Dr. GPCR Podcast, Dr. Dmitry Veprintsev discusses the importance of asking the right GPCR question. It’s not just about learning the techniques; it’s about curiosity! 👀 Do you remember any question that changed your perspective completely? 💡 ✳️Visit https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #GPCRScience | Dr. GPCR Ecosystem
GPCR Podcast, Dr. Dmitry Veprintsev discusses the importance of asking the right GPCR question. 💡 ✳️Visit https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr. GPCR Podcast In Ep.163 of the Dr. GPCR Podcast, Dr. Dmitry Veprintsev discusses the importance of asking the right GPCR question. 💡 ✳️Visit https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.
- Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process of PTH1R: New computational insights into its molecular interactions bring us closer to better osteoporosis treatments! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr #drgpcr Published on February 6, 2025 Category GPCR Weekly News Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr
- Dr. Daniel Isom | Dr. GPCR Ecosystem
GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Annette Gilchrist | Dr. GPCR Ecosystem
GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- Dr. Sudarshan Rajagopal | Dr. GPCR Ecosystem
His lab is also interested in identifying novel signal transduction mechanisms of GPCRs, such as the GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment? That’s precisely what Dr. Kotliar from the Sakmar lab made possible! In Ep.167 of the Dr. GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research community. ✳️ Listen to the episode: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast | Dr. GPCR Ecosystem
Home → Flash News → What if you could map GPCR-RAMP interactions across the entire superfamily in a single GPCR Podcast, we chat with Drs. library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations GPCR Podcast What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment GPCR Podcast, we chat with Drs.
- A new study from the Hudson Lab at the University of Glasgow shows that the FFA receptor antagonist AH7614 is actually an inverse agonist - suppressing fat cell formation, boosting lipolysis and reducing glucose uptake. Explore how targeting FFA4 could help fight metabolic disorders. Catch up with the latest research conducted in the Hudson lab in Ep. 161 of the Dr. GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/inverse-agonism-of-the-ffa4-free-fatty-acid-receptor-controls-both-adipogenesis-and-mature-adipocyte-function #GPCR #drGPCR #FFA4 #metabolism #adipocytes” | Dr. GPCR Ecosystem
GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com #GPCR #drGPCR #FFA4 #metabolism #adipocytes” Published on April 7, 2025 Category GPCR Weekly News A GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https:// www.ecosystem.drgpcr.com
- This new study reveals how the conformation of parathyroid hormone (PTH) and the C-terminal helix α5 of Gα regulate the selective coupling of PTH1R to Gs or Gq. Through Cryo-EM and single-cell experiments, the authors show differences in binding affinity, duration, and strength. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com /structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type -1-receptor #gpcr #drgpcr Published on April 28, 2025 Category GPCR Weekly News This new study reveals GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com -1-receptor #gpcr #drgpcr Previous Next Recent Articles
- Dr. Bryan Roth | Dr. GPCR Ecosystem
GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
- How does a superagonist activate M2 muscarinic receptors? New simulations reveal the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR activation! Catch the full story in the Ecosystem! https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/visualizing-agonist-induced-m2-receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics | Dr. GPCR Ecosystem
the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR -receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics Published on March 31, 2025 Category GPCR Weekly News How does a superagonist activate M2 muscarinic the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR -receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics
- Do you remember the first time you were left alone in the lab with an experiment? 🤔 Did your experience compare to Dr. Brian Hudson’s? 😄 Tune into this week’s Dr. GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. Hudson to years of groundbreaking research at the University of Glasgow. Don’t miss out! ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr Published on March 17, 2025 Category Dr. GPCR Podcast Do you remember the first time you were left alone in the lab with an experiment? GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr Previous Next Recent Articles
- Dr. Peter Robert Banks | Dr. GPCR Ecosystem
GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks
