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Results found for "Stephen S G Ferguson"
- The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe?
September 2022 "The G-protein-coupled bile acid receptor, Gpbar1 or TGR5, is characterized as a membrane
- GPCR kinase phosphorylation of distal C-tail sites specifies βarrestin1-mediated signaling by...
September 2022 "G protein-coupled receptor (GPCR) kinases (GRKs) and arrestins mediate GPCR desensitization
- ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the...
Single nucleotide polymorphisms (SNPs) in the Adhesion G Protein-Coupled Receptor L3 (ADGRL3) gene are
- GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
October 2022 "Protease-activated receptor 2 (PAR2) is a G-protein-coupled receptor (GPCR) activated by
- Comparative study of neuropeptide signaling systems in Hemiptera
Here, 33 neuropeptide precursors and 48 putative neuropeptide G protein-coupled receptor (GPCR) genes
- Prostaglandin signaling in ciliogenesis and development
Many G-protein-coupled receptors (GPCRs) including EP4 are localized in cilia for modulating cAMP signaling
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
Significant advancements in the cellular biology of G protein-coupled receptors (GPCRs) about a novel
- 📰 GPCR Weekly News, May 8 to 14, 2023
GPCR Activation and Signaling Ligand-induced activation and G protein coupling of prostaglandin F2α receptor GPCRs in Oncology and Immunology DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil
- A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology in...
Pharmacology in Cell Membranes and Living Cells "Conformational biosensors to monitor the activation state of G
- Nuclear localization of histamine receptor 2 in primary human lymphatic endothelial cells
In this work, we report the subcellular localization of histamine receptor 2 (H2R), a G protein-coupled
- Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR
the gut-brain axis, have entered a strategic research collaboration to identify and validate novel G
- New Resources in GPCRdb
Gáspár Pándy-Szekeres ) will present and demonstrate the newest resources of the GPCRdb: 1) the new G
- Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
mutation in exon 6 of the CaSR gene Reviews, GPCRs, and more Insight into structural properties of viral G
- Statin-induced increase in actin polymerization modulates GPCR dynamics and compartmentalization
actin cytoskeleton in regulating the dynamics of the serotonin1A receptor, a crucial neurotransmitter G
- GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation
inflammasome activation in macrophages "The putative medium-chain free fatty acid receptor GPR84 is a G
- Lysine 101 in the CRAC Motif in Transmembrane Helix 2 Confers Cholesterol-Induced Thermal...
in Transmembrane Helix 2 Confers Cholesterol-Induced Thermal Stability to the Serotonin 1A Receptor "G
- Identification and functional characterization of the sulfakinin and sulfakinin receptor in the...
variety of behavioral processes and physiological functions in invertebrates through the interaction with G-protein-coupled
- Dr. GPCR Updates
[Nature’s peptides return:](https://ecosystem.drgpcr.com/so/bdPSktt-s/c?
- Confo Therapeutics Doses First Subjects In Phase 1 Clinical Trial Of CFTX-1554 For The Treatment ...
Ghent, Belgium – March 10, 2022 – Confo Therapeutics, a leader in the discovery of medicines targeting G-protein
- Newly launched antibody libraries put hard-to-drug targets within reach
To target hard-to-drug targets like G protein-coupled receptors (GPCRs), more libraries, including better
- 📰 GPCR Weekly News, February 27 to March 5, 2023
Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G Developing novel antifungals: lessons from G protein-coupled receptors.
- Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or sy
rodent model of 3-day recurrent hypoglycemia, we first checked expression of counterregulatory hormone G-protein
- Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent GPCR...
Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent GPCR ligands "G-protein
- Gαs and Gαq/11 protein coupling bias of two AVPR2 mutants (R68W and V162A) that cause nephrogenic di
AVPR2 is a kind of G protein coupled receptor (GPCR) and mainly couples with Gαs protein leading to cAMP
- Combined docking and machine learning identify key molecular determinants of ligand pharmacological
September 2022 "G protein‐coupled receptors (GPCRs) are valuable therapeutic targets for many diseases
- PAR-Induced Harnessing of EZH2 to β-Catenin: Implications for Colorectal Cancer
September 2022 "G-protein-coupled receptors (GPCRs) are involved in a wide array of physiological and
- Sosei Heptares Enters Antibody Discovery Agreement with Twist Bioscience to Discover and Develop ...
its silicon platform, announced a strategic collaboration to discover therapeutic antibodies against G
- Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
November 2022 "Recently determined structures of class C G protein-coupled receptors (GPCRs) revealed
- Precise druggability of the PTH type 1 receptor
Class B G protein-coupled receptors (GPCRs) are notoriously difficult to target by small molecules because
- A Chemical Biology Toolbox Targeting the Intracellular Binding Site of CCR9: Fluorescent Ligands ...
A conserved intracellular allosteric binding site (IABS) has recently been identified at several G protein-coupled



