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Results found for "GPCR-RAMP interactions"
- Protein Uncoupling as an Innovative Practice in Diabetes Mellitus Treatment: A Metabolic Disorder
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- Discovery of 3(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligand
August 2022 "Abstract Sigma receptor is a transmembrane non-GPCR protein expressed mainly in the endoplasmic Therefore, S1R ligands possess a variety of potential clinical applications with a great interest in that all the compounds showed the critical salt bridge with Glu172 with variable degrees of π-stacking interaction Read more at the source #DrGPCR #GPCR #IndustryNews
- Delineation of GPR15 receptor-mediated Gα protein signaling profile in recombinant mammalian cell
September 2022 "The GPR15 receptor is a G protein-coupled receptor (GPCR), which is activated by an endogenous GPR15 signals through the Gi/o pathway to decrease intracellular cyclic adenosine 3',5'-monophosphate (cAMP Furthermore, the GPR15 receptor signals through Gi/o to inhibit cAMP accumulation, which could be blocked Read more at the source #DrGPCR #GPCR #IndustryNews
- FSH and bone: Comparison between males with central versus primary hypogonadism
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- Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal
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- Orion Shares New Data on its Latest Best-in-Class Drug Candidate
discovery and development company unlocking the therapeutic potential of G Protein-Coupled Receptors (GPCRs Vice-President Drug Discovery, will present Orion’s novel technology for targeting undrugged peptidergic GPCRs discovery platform, one of the fastest drug discovery solutions in the industry for targeting peptidergic GPCRs antagonist, OB-004, demonstrating the ability of this powerful platform to rapidly identify best-in-class GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- Learn more about Neurocrine Biosciences with their new video
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- Drug Discovery Picks Up the Pace, Stays on Target
drug efficacy analyses, and toxicity studies; technologies that stabilize G protein–coupled receptors (GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- ShouTi Introduces Basecamp Bio as a Wholly Owned Subsidiary to Expand Pipeline and Partnerships
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- Identification of hub genes in the subacute spinal cord injury in rats
analysis (WGCNA) were performed using R software, and functional enrichment analysis and protein–protein interaction Finally, the relative mRNA expression level of central genes was verified by RT-PCR." Read more at the source #DrGPCR #GPCR #IndustryNews
- Tectonic Therapeutic Strengthens Leadership Team
Tectonic Therapeutic, Inc. a pre-clinical stage biotechnology company transforming the discovery of novel GPCR-targeted Read more at the source #DrGPCR #GPCR #IndustryNews
- 2nd IRN i-GPCRnet, September 30 to October 1st, 2022. University of Wurzburg, Germany
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- Carola Weiss joins InterAx Biotech AG as VP Business Development
February 2022 "Switzerland Today, InterAx Biotech is pleased to announce that Carola Weiss has joined Read more at the source #DrGPCR #GPCR #IndustryNews
- Oxford Professor Of Chemistry And Founder Of Therapeutic Company Wins Two International Awards
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- Exploring pharmacological inhibition of G q/11 as an analgesic strategy
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- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
The expression markers related to odontoblastic differentiation of hDPSCs were observed by qPCR and chemical The G protein and intracellular Ca2+ were detected, respectively, by qPCR and Fluo-4AM Ca2+ fluorescent Read more at the source #DrGPCR #GPCR #IndustryNews
- C3aR plays both sides in regulating resistance to bacterial infections
the complement pathway results in the production of bioactive C3a, a product of C3 cleavage, which interacts Read more at the source #DrGPCR #GPCR #IndustryNews
- Novo Nordisk moves to strengthen obesity efforts
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- Fentanyl activates ovarian cancer and alleviates chemotherapy-induced toxicity via opioid...
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- Neurotransmitters: Potential Targets in Glioblastoma
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- Discovery On Target, October 17-20, 2022, Boston, USA
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- Case Report of a Juvenile Patient with Autism Spectrum Disorder with a Novel Combination of Copy...
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- C1-inhibitor influence on platelet activation by thrombin receptors agonists
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- Naggie and Rajagopal Elected Members of American Society for Clinical Investigation
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- ChemoCentryx Announces EU Approval of TAVNEOS® (avacopan) for the Treatment of ANCA-Associated ...
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- Addex Therapeutics To Release Full-Year 2021 Financial Results And Host Conference Call On March 10
media at 16:00 CET (15:00 GMT / 10:00 EST / 07:00 PST) the same day. " Read more at the source #DrGPCR #GPCR
- Trevena Reports Second Quarter 2022 Results and Provides Business Update
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- Serotonin Receptor 5-HT2A Regulates TrkB Receptor Function in Heteroreceptor Complexes
Here, we demonstrate a physical interaction between 5-HT2A and TrkB in vitro and in vivo using co-immunoprecipitation Read more at the source #DrGPCR #GPCR #IndustryNews
- Research Network on Signal Transduction (ERNEST) has established an Emergency Fund for Ukrainian ...
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- Upregulation of Phospholipase C Gene Expression Due to Norepinephrine-Induced Hypertrophic Response
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