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- RGS7-ATF3-Tip60 Complex Promotes Hepatic Steatosis and Fibrosis by Directly Inducing TNFα
Protein Signaling 7 (RGS7) in hyperlipidemia-dependent hepatic dysfunction. " Read more at the source #DrGPCR
- Aβ peptides stabilize GPCRs in inactive form and trigger inverse agonism in Alzheimer's disease
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- Location bias contributes to functionally selective responses of biased CXCR3 agonists
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- Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling
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- Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to inv
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- A cryptic mode of GPCR regulation revealed
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- Protein Uncoupling as an Innovative Practice in Diabetes Mellitus Treatment: A Metabolic Disorder
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- Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures
CB1R), β2 adrenergic receptor (β2 AR) and A2A adenosine receptor (A2A AR). " Read more at the source #DrGPCR
- The Gluopsins: Opsins without the Retinal Binding Lysine
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- Diversity and specificity in location-based signaling outputs of neuronal GPCRs
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- Hear the sounds: the role of G protein-coupled receptors in the cochlea
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- Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to...
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- Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...
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- A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in...
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- The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor
participate in a molecular mechanism to trigger β-arrestin recruitment. " Read more at the source #DrGPCR
- Ermium Therapeutics has constituted its SAB
pharmacology, immunology, drug discovery and development for auto-immune diseases" Read more at the source #DrGPCR
- Coincident Regulation of PLCβ Signaling by Gq-Coupled and μOpioid Receptors Opposes Opioid- Mediated
targets that would allow for lower dose utilization of opioid analgesics. " Read more at the source #DrGPCR
- The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1
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- FSH and bone: Comparison between males with central versus primary hypogonadism
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- Function and structure of bradykinin receptor 2 for drug discovery
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- Specific Functions of Melanocortin 3 Receptor (MC3R)
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- Diversification of PAR signaling through receptor crosstalk
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- Deciphering the signaling mechanisms of β-arrestin1 and β-arrestin2 in regulation of cancer cell...
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- β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the...
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- Activation of the human chemokine receptor CX3CR1 regulated by cholesterol
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- Meet Peter McNamara, Ph.D., Tectonic’s SVP, Head of Research
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- Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors
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