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Search results for "James Hassard"
Results found for "James Hassard"
- GPCR Masterclass Live Courses | Dr. GPCR Ecosystem
The conversation stays at the right level because everyone in the room speaks the same scientific language What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended
- Custom Molecules, Fluorescent Probes: When Chemists Think Like Biologists with Dr. Maria Majellaro from Celtarys | Dr. GPCR Ecosystem
When the time came to decide whether to leave the lab and lead Celtarys into biotech, she took the leap
- GPCR Masterclass: Advanced Pharmacology & Drug Discovery | Dr. GPCR
Calebiro University of Birmingham Jakob Höppner Endocrine Unit, Massachusetts General Hospital and Harvard What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended
- GPCR Webinars | Dr. GPCR Ecosystem
Together in the Room Scientists from around the world, in the same conversation. If this is your first session, there's a lot more where this came from. Want to Go Deeper? session, the full recording becomes available on demand so scientists in every time zone can access the same
- Why Mosquitoes Hunt You: GPCR Control of Blood Feeding and Mating | Dr. GPCR Ecosystem
What pulls Duvall back to this receptor personally is its apparent conservation: the same NPY family mosquito rectum, a structure Duvall says she did not know existed as a distinct entity until the result came The same NPY family Duvall calls her favorite includes a receptor in the female mosquito that detects Because Aedes aegypti transmits Zika, dengue, and chikungunya through the same host seeking behavior,
- Univeristy Lecturers Details | Dr. GPCR Ecosystem
Your name and expertise remain at the heart of the course, continuing to inspire scientists long after You’ll be asked for: Instructor info – name, email, affiliation, short bio, photo, and optional social What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended the technical and human challenges we encounter in our work GPCR researcher Contact Contact us First name * Last name Email* Write a message Submit
- Joseph Kim: Structural Biology and Drug Discovery at GPCRs | Dr. GPCR Ecosystem
Joseph Kim: My name is Joseph Kim. I go by Joe. Joseph Kim: It actually came from discussions with Ashish when I first joined the lab. The second “aha moment” came when I solved the structures of the μ-opioid and κ-opioid receptors bound
- Dr. Terry Hebert: A Pharmacologist Thinking Through Lockdown | Dr. GPCR Ecosystem
journal clubs, daily Slack and Zoom contact, a faculty-vs-student trivia night — the lab's continuity came labs sharing a floor, shared equipment, and a public transit system that funnels everyone through the same
- Smells Like GPCR Spirit: Cracking Olfactory Codes with Alessandro Nicoli | Dr. GPCR Ecosystem
The Moment Chemistry Met Biology Nicoli’s turning point came when he realized that molecules weren’t
- Dr. Aurélien Rizk | Dr. GPCR Ecosystem
Aurelien Rizk shared his journey of using these disciplines in biology and how his company, Interax, came
- Jennifer Pluznick: Olfactory Receptors in the Kidney and the Gut-Microbe Signal | Dr. GPCR Ecosystem
The name "olfactory receptor" narrows the imagination. Dr. Quotes "I famously said that I wasn't sure I could really trust the data because these crazy receptors came
- Jacob Lee and Jin Cho: Rebuilding the Software Layer Under Modern Research | Dr. GPCR Ecosystem
Cho came from engineering software for military drones at General Atomics, and was stunned when he saw The GeneMode story starts with two teenagers in the same high-school classroom, different majors, different Although both went to the same college, Jacob and Jin choose different career paths.
- Beatriz Blanco-Redondo: Adhesion GPCR Discovery in Drosophila | Dr. GPCR Ecosystem
The receptors were named after condiments, ketchup, mayo, and remulate, not out of irreverence, but because Naming receptors after condiments signals where the field actually stands Ketchup, Mayo, and Remulate were named in the absence of functional data that would normally guide nomenclature. The playfulness of the naming reflects the honesty of the situation. 3. If a failed approach were citable, it would shorten the path for the next researcher attempting the same
- Randy Hall: Adhesion GPCRs and the Tail Nobody Wanted | Dr. GPCR Ecosystem
He also explains how he came to write the memoir of his mentor, a project he pitched three times over partners he found for beta 1 and beta 2 offered an explanation for how two subtypes coupling to the same Signaling increased massively instead, and the same held for BAI1.
- Ross Cheloha: Nanobody-GPCR Conjugates and the Engineering of Receptor Selectivity | Dr. GPCR Ecosystem
Trained in the Gelman lab at the University of Wisconsin-Madison and later in the Ploegh lab at Harvard The biology may have been using this distinction all along: two natural ligands for the same receptor short PTH fragment to a PTHR1-selective nanobody produces a ligand selective for that subtype; the same experiment, Cheloha said, opened more mechanistic doors than anything he had produced before - and it came He completed his postdoctoral training at MIT and Harvard Med School in the lab of Hidde Ploegh , where
- Paul Insel: Unbiased Discovery and the GPCRs We've Been Missing | Dr. GPCR Ecosystem
The biggest discoveries came from asking what was being overlooked Dr.
- Sam Hoare: Receptor Residence Time and GPCR Data Analysis | Dr. GPCR Ecosystem
And the one that didn't work in vivo came off in fifteen minutes."
- Graciela Piñeyro: Partial Agonism, Receptor Recycling, and the Limits of Bias | Dr. GPCR Ecosystem
tolerance better than internalization itself Protean agonism and multiple active conformations — how the same Piñeyro watched the same ligand behave as an agonist under one condition and an inverse agonist under The resolution came not from a new experiment but from a model — protean agonism, as Kenakin had just THC's long-term effects on adolescent cognition sits alongside the analgesic one, and both require the same
- GPCR University | Dr. GPCR Ecosystem
What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended This person must email hello@drgpcr.org indicating how many people will register for the course, the names
- Brian Arey - Part 2: GPCR Drug Discovery and the Science Nobody Publishes | Dr. GPCR Ecosystem
Intuition as hypothesis generator: what comes before the data Selected Quotes "There was a paper that came
- Lin and Ball: GPCR Antibody Characterization and the Recombinant Shift | Dr. GPCR Ecosystem
Ball recounts his company's president going pale when the subject came up: every commercial antibody
- Michel Bouvier: BRET, Biased Agonism, and the Tools That Changed GPCR Pharmacology | Dr. GPCR Ecosystem
Pharmacological chaperones came from a project that looked dead A PhD student testing the effect of nephrogenic Following his Ph.D. in Neurological Sciences at the same university in 1985, he completed a post-doctoral
- Elva Zhao: G Protein Regulation and Biased Signaling at the GLP-1 Receptor | Dr. GPCR Ecosystem
biased agonism: the differential engagement of downstream pathways by distinct ligands acting at the same The correction, for Zhao, came slowly - driven by a mentor patient enough to make asking safe, and by
- Revvity | Dr. GPCR Ecosystem
Learn how pH Sense changes the game for drug discovery. Dr.
- Tore Bengtsson: Rethinking β₂-Adrenergic Signaling in Metabolic Disease | Dr. GPCR Ecosystem
Bengtsson’s key scientific breakthroughs came from an unexpected experimental result: glucose uptake
- Antony Boucard: Adhesion GPCRs and the Molecular Code of Synapse Formation | Dr. GPCR Ecosystem
biochemistry, cell communication, disease, and the students other institutions overlooked — finally came Having a particular interest for a three-member family named latrophilins, his lab seeks to decipher
- GPCR Courses | Dr. GPCR Ecosystem
First name Last name Email* Join Our Mailing List Count me in! What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended
- The Practical Assessment of Signaling Bias | Dr. GPCR Ecosystem
stabilize unique receptor conformations, leading to distinct signaling outcomes—even when binding to the same minimizing side effects The session wraps up with a lively Q&A , allowing attendees to explore this game-changing . 📌 Receptors are Dynamic Players 🔹 Different ligands trigger unique receptor states, meaning the same






















