Network or Miss Out One powerful shift came when Sokhom leaned into networking—despite being an introvert “What fascinates me is how the same molecule behaves differently depending on one amino acid.”

Andrew Tobin University of Glasgow Jakob Höppner Endocrine Unit, Massachusetts General Hospital and Harvard What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended

When the time came to decide whether to leave the lab and lead Celtarys into biotech, she took the leap

Joseph Kim: My name is Joseph Kim. I go by Joe. Joseph Kim: It actually came from discussions with Ashish when I first joined the lab. The second “aha moment” came when I solved the structures of the μ-opioid and κ-opioid receptors bound

. << Back to podcast list Strategic Partner(s) Jane Lamerdin and Gaurav Agrawal: Building GPCR Assays About the Guests Jane Lamerdin is VP of R&D at Eurofins DiscoverX, where she oversees development of The guests frame their work as talking to peers who understand the same pains, not selling a catalog.

Together in the Room Scientists from around the world, in the same conversation. If this is your first session, there's a lot more where this came from. Want to Go Deeper? session, the full recording becomes available on demand so scientists in every time zone can access the same

What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended

Your name and expertise remain at the heart of the course, continuing to inspire scientists long after You’ll be asked for: Instructor info – name, email, affiliation, short bio, photo, and optional social What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended the technical and human challenges we encounter in our work GPCR researcher Contact Contact us First name * Last name Email* Write a message Submit

journal clubs, daily Slack and Zoom contact, a faculty-vs-student trivia night — the lab's continuity came labs sharing a floor, shared equipment, and a public transit system that funnels everyone through the same

The name "olfactory receptor" narrows the imagination. Dr. Quotes "I famously said that I wasn't sure I could really trust the data because these crazy receptors came

Aurelien Rizk shared his journey of using these disciplines in biology and how his company, Interax, came

The Moment Chemistry Met Biology Nicoli’s turning point came when he realized that molecules weren’t

Cho came from engineering software for military drones at General Atomics, and was stunned when he saw The GeneMode story starts with two teenagers in the same high-school classroom, different majors, different Although both went to the same college, Jacob and Jin choose different career paths.

The receptors were named after condiments, ketchup, mayo, and remulate, not out of irreverence, but because Naming receptors after condiments signals where the field actually stands Ketchup, Mayo, and Remulate were named in the absence of functional data that would normally guide nomenclature. The playfulness of the naming reflects the honesty of the situation. 3. If a failed approach were citable, it would shorten the path for the next researcher attempting the same

And the one that didn't work in vivo came off in fifteen minutes."

The biggest discoveries came from asking what was being overlooked Dr.

Trained in the Gelman lab at the University of Wisconsin-Madison and later in the Ploegh lab at Harvard The biology may have been using this distinction all along: two natural ligands for the same receptor short PTH fragment to a PTHR1-selective nanobody produces a ligand selective for that subtype; the same experiment, Cheloha said, opened more mechanistic doors than anything he had produced before - and it came He completed his postdoctoral training at MIT and Harvard Med School in the lab of Hidde Ploegh , where

tolerance better than internalization itself Protean agonism and multiple active conformations — how the same Piñeyro watched the same ligand behave as an agonist under one condition and an inverse agonist under The resolution came not from a new experiment but from a model — protean agonism, as Kenakin had just THC's long-term effects on adolescent cognition sits alongside the analgesic one, and both require the same

Intuition as hypothesis generator: what comes before the data Selected Quotes "There was a paper that came

Learn how pH Sense changes the game for drug discovery. Dr.

Ball recounts his company's president going pale when the subject came up: every commercial antibody

Pharmacological chaperones came from a project that looked dead A PhD student testing the effect of nephrogenic Following his Ph.D. in Neurological Sciences at the same university in 1985, he completed a post-doctoral

biased agonism: the differential engagement of downstream pathways by distinct ligands acting at the same The correction, for Zhao, came slowly - driven by a mentor patient enough to make asking safe, and by

biochemistry, cell communication, disease, and the students other institutions overlooked — finally came Having a particular interest for a three-member family named latrophilins, his lab seeks to decipher

Bengtsson’s key scientific breakthroughs came from an unexpected experimental result: glucose uptake

First name Last name Email* Join Our Mailing List Count me in! What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended

stabilize unique receptor conformations, leading to distinct signaling outcomes—even when binding to the same minimizing side effects The session wraps up with a lively Q&A , allowing attendees to explore this game-changing . 📌 Receptors are Dynamic Players 🔹 Different ligands trigger unique receptor states, meaning the same