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Results found for "Jie Heng"
- Using Live-cell High-Content Screening to Characterize CB2 Ligands: Insights From 16 Synthetic Cannabinoids
Ki values were then calculated using the Cheng–Prusoff equation, with CELT-331 parameters fully reported
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
However, the receptors that these medicines target have been described as the ‘low-hanging’ fruit, and Hence PROcisionXᵀᴹ is one of the fastest discovery platforms in industry, and one that is uniquely capable the fully integrated PROcisionXᵀᴹ discovery platform Structure-based validation of Orion’s approach Zheng
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
subtype-selective ligands for dopamine receptors and adenosine receptors (He, Ben, Kuang, Wang & Kong, 2016; Kuang, Feng
- Decoding β-Arrestins: from Structure to function
states: methods and implications The formation of functional complexes involving GPCRs and β-arrestins hinges
- Fluorescence based HTS compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
determined to be 30.1 ± 1.7 nM corresponding to apparent Ki ± SEM = 15.7 ± 0.9 nM according to the Cheng-Prusoff
- The Perils and Guardrails of Modifying Signalling Proteins in Bioassays
Schlander M, Hernandez-Villafuerte K, Cheng CY, Mestre-Ferrandiz J, Baumann M. Protein Eng Des Sel. 2016;29(12):583-594. 47. Crilly SE, Ko W, Weinberg ZY,Puthenveedu MA. Teng X, Chen S, Wang Q, Chen Z, Wang X, Huang N, et al.
