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Results found for "Remi Janicot"
- Orthosteric vs Allosteric Interactions— and the pHSense Shift in Internalization
From Bench Frustrations to Breakthrough Design For decades, GPCR trafficking research relied on overexpression
- Unlocking Cell's Secrets: Spontaneous β-Arrestin-Membrane Preassociation Drives Receptor-Activation
the plasma membrane, enabling it to independently reach clathrin-coated pits (CCPs) without solely relying
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
note that this scavenging role does not occur in all chemokine receptor systems such as CXCR4, which relies
- Fluorescence based HTS compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
Thus, in order to complete the studies, quantitative live cell microscopy assay relies on cell segmentation
- The Perils and Guardrails of Modifying Signalling Proteins in Bioassays
Bioassays for interrogating GPCR structure and function typically rely on protein tags or modifications
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