the Monash Institute of Pharmaceutical Sciences, working across the groups of Barrie Kellam and Steve Hill

It meant the receptor could survive in harsh short-chain detergents that had previously killed it instantly

Research Mike discussed the ongoing research on a drug that inhibits cytokine synthesis, its potential in killing

Arun is currently an Associate Professor & Joy Gill Chair Professor, Intermediate Fellow, Wellcome Trust

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Industry can screen tens of millions of compounds in the time it takes to write a grant. But in academia, you also can't screen 30 million cell lines in an afternoon.

shaped his work: a receptor is not a fixed object with a fixed output but a system that changes by the millisecond Scientific Themes of the Conversation Receptors as temporal systems: signaling that shifts across milliseconds The body gets used to being ill Given long enough, a system drifting out of balance stops recognizing pharmacology: a science that has to produce something 29:25 Natural language processing, and reading millions jelly on the table 01:45:49 Disease trajectory modifiers: giving compounds to people who are not yet ill

co-founded Algorizk, a company that created real-time physics simulations for education, serving over 1 million

linked to blood pressure is activated by small-molecule metabolites produced by gut bacteria at low millimolar

The route from "intrathecal only" to "oral pill" runs through isoform selectivity. signaling 07:49 Why the mu receptor still anchors his lab 09:51 The specificity puzzle — why ERK does a million

Taking time to think about what you're doing is way more valuable than just trying to do the next ten million