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Foord reflects on his path from academic neuroendocrinology to introducing molecular biology and molecular Trained in neuroendocrinology, he helped bring molecular biology into traditionally pharmacology-driven The CGRP story illustrates how structural biology and pharmacology intersect with corporate decisions He argues that integrating structural biology, computational pharmacology, and genetics may still be For younger scientists, his advice centers on doing work you genuinely enjoy, finding supervisors who

What emerges is a quiet argument that the structural shifts the pandemic forced — project planning in Civic responsibility in returning to the bench — Deconfining a research center slowly, with planning research center closed again, the team would still have something to analyze, something to write. The research center was deconfining at 20% capacity the week of the recording. Dr. Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

collaborative chemistry enabled in designing receptor-targeted fluorescent ligands The moment when structural Robert Turner Professor of Diabetic Medicine at the University of Oxford , working within the Oxford Centre His group develops imaging and chemical biology tools to reveal how GLP-1 and GIP receptors operate within David Hodson on the Web Radcliffe Department of Medicine Islet Biology Lab University of Birmingham Upcoming Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Ray Stevens in 2013 solving several GPCR crystal structures, including that of the first serotonin receptor Bryan Roth where I established GPCR structural biology and learned the ins and outs of molecular pharmacology started my own lab at the Icahn School of Medicine at Mount Sinai in NYC, where I have been working on structure-function Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

signaling mechanisms employed by these atypical 7-transmembrane receptors, combining biochemical and structural approaches with cell biology and in vivo models. begun studying GPCR signaling pathways that operate within the primary cilium, a tiny antenna-shaped structure Prior to that, Ben received his Ph.D. from UCSF in 2008, where he worked with David Julius on the structure Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Martin Audet Structural biologist, pharmacologist, and a professor of pharmacology at Université de Sherbrooke the AudetLab located at the Institute of Pharmacology of Sherbrooke and is an emerging leader in the structural biology of G Protein-Coupled Receptors and passive transporters. Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

biology to delineate mechanisms of action. The structure was first snapshot of the agonist- and G protein-bound GPCR, providing valuable models One example of our recent work surrounds a structure-based effort to develop ligands that specifically changes in G protein structure. Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

received a prestigious Gates Cambridge Scholarship to study for a Ph.D. at the MRC Laboratory of Molecular Biology His Ph.D. work has been focused on understanding the structure and activation of Class D fungal GPCRs developed novel tools and methodologies to study fungal GPCRs which allowed the determination of the first structures Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Biologist - Confo Therapeutics Associate Director/Director, Platform & Hit-ID Chemistry Lead - Septerna Position - Autonomous University of Barcelona GPCR Molecular Pharmacologist - Schrödinger Scientist - Biology - Superluminal Medicines Scientist I Cell Biology - Tectonic Therapeutic Adhesion GPCRs A force-sensitive Structural and Molecular Insights into GPCR Function Structural insights into prolactin-releasing peptide and biased signaling in the motilin receptor 🔎 GPCR KEYWORDS GPCR , structural biology , biased signaling

The overall goal of her research program is to obtain rigorous mechanistic insights into the structure To this end, her lab uses several computational structural biology tools and rational drug design approaches Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

She developed expertise over the past two decades studying structure/function relationships of GPCRs Her research centers on developing nanobody-ligand conjugates to target GPCRs, with a focus on receptors Monserrat Avila Zozaya I did a PhD in cell biology at CINVESTAV, Mexico. About John Azietaku John Teye Azietaku,PhD is a trained pharmacist, holding a Ph.D. in Drug Discovery Biology Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

He earned his PhD at MIT in the laboratory of Lawrence Stern, where he studied structure-function relationships skipping fragment-based screening and going directly to full bivalent IgG, the team hands functional biology He looks for target classes where existing platforms have already failed — not because the biology is He earned his Ph.D. at the Massachusetts Institute of Technology, where he studied MHC class II structure-function Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

AI is reshaping how we understand protein dynamics , but only when driven by deep biological questions Boston Children’s Hospital and Harvard Medical School, where he deepened his understanding of pain biology discovery, he later co-founded Superluminal Medicines, a company using machine learning to explore GPCR structure-function Ajay’s work sits at the intersection of GPCR biology, AI, and translational medicine. Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

She developed expertise over the past two decades studying structure/function relationships of GPCRs me to shape a swiss start-up company from a scientifc idea to a thriving Biotech focusing on Systems Biology Discovering new aspects of PAR signaling is important for increasing the fundamental knowledge of GPCR biology protease-activated receptors, particularly PAR1, and over the years she has discovered novel aspects of GPCR biology Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

She is also the Associate Director of the City of Hope Comprehensive Cancer Center. Dr. Caltech, she became the director of biomolecular simulations at the Materials and Process Simulation Center Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Fan is currently an associate professor of Pharmacology and Pathology and Cell Biology at Columbia University Qing is a structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Transform your biotech idea or data into a clear, strategic roadmap with aligned biology, timelines, Welcome Biotech Growth Wherever You Are in Discovery—Let’s Build a Plan That Moves You Forward Align your biology Confidence Decisions, Not More Data We'll define what matters, when to decide, and how to act—based on your biology guides program momentum Focus resources where they’ll change outcomes No More Strategy Swirl I build structure up clear deliverables across internal and CRO teams Keep cross-functional teams moving with shared structure

Initially driven by a general passion for biology and a childhood dream of being an astronaut, he began “The goal is to smash all the amazing biology together and make a drug.” Structural Biology Roadblocks: The Cryo-EM Challenge One bottleneck in Ben’s work is visualizing binding Still, by collaborating with structural biology teams and combining cryo-EM with NMR , his lab is narrowing Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Sudha Shenoy is currently an Associate Professor in Medicine & Cell Biology in the Division of Cardiovascular Medicine, Duke University Medical Center. Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

the GPCR research community — bridging wet-lab experimentation, open-access tools, and computational biology GPCR superfamily , building a digital and physical toolkit to systematically investigate GPCR-RAMP biology The system is modular and adaptable, opening doors for systems biology and context-specific interaction As the field advances, the computational layer — including AlphaFold and structural prediction tools Ilana uses chemical biology-based methods to study the regulation and protein-protein interactions of

Biology-First, Data-Driven Solutions Every recommendation is rooted in GPCR biology, pharmacology experience Operational Discipline I instill structure and consistency across every phase of your discovery process Yamina brings the clarity, rigor, and structured decision-making that keeps programs on track. Therapeutics Before working with Yamina, we had solid internal momentum but needed to better align our biology Her input helped us structure the screening funnel, define clear go/no-go criteria, and integrate ADME

Brain’s work there primarily focused on structure prediction of GPCRs from sparse experimental data. of California in San Francisco to continue his training as a postdoctoral researcher where he used structural Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Premont obtained his B.S. in Biology and Chemistry at the California Institute of Technology in 1985, In our work, we utilize methods including structural biology and proteomics, molecular biology and biochemical Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Premont obtained his B.S. in Biology and Chemistry at the California Institute of Technology in 1985, In our work, we utilize methods including structural biology and proteomics, molecular biology and biochemical Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Premont obtained his B.S. in Biology and Chemistry at the California Institute of Technology in 1985, In our work, we utilize methods including structural biology and proteomics, molecular biology and biochemical Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Premont obtained his B.S. in Biology and Chemistry at the California Institute of Technology in 1985, In our work, we utilize methods including structural biology and proteomics, molecular biology and biochemical Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Sri Kosuri Sri is a biologist that has helped build technologies, labs, and companies in synthetic biology He is passionate about developing more rational ways to understand and engineer biology. empirically exploring questions in protein biochemistry, human genetic variation, gene regulation, chemical biology , synthetic biology, and functional genomics. Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Nikolaus Heveker's lab at the CHU Sainte-Justine Research Center on chemokine receptor structure–function Splice variants aren't just structural — they signal differently. career 06:30 An empty lab and the chemokine redundancy problem 09:00 A master's, old-school molecular biology During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

Nanoengineering Department, Ken Vecchio helping set the foundation for the Nanoengineering Materials Research Center Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology

GPCR webinars are live online scientific sessions focused on G protein-coupled receptor (GPCR) biology These webinars are ideal for: • GPCR pharmacologists • Medicinal chemists working on receptor targets • Structural biologists • Translational scientists • Biotech and pharmaceutical researchers • Postdoctoral fellows Calcium and signaling assays • Drug–receptor kinetics • Translational pharmacology strategies • GPCR structure–function These programs are designed for scientists seeking advanced, mechanism-focused training in GPCR biology