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Results found for "Howard A Rockman"
- From Failed Experiments to Predictive GPCR Models
While others refined lab techniques, he found himself gravitating toward structural models in his spare
- High-Content Screening for GPCR Programs: Overcoming Assay Limitations with Fluorescent Ligands
However, their limitations become increasingly important as drug discovery moves toward high-information
- Adhesion GPCR Consortium Newsletter - May 2024
A small step toward leveling the playing field.
- 📰 GPCR Weekly News, January 30 to February 5, 2023
The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards
- Odorant receptors – a bit of smell for drug discovery
The development of antibodies directed towards an OR could either drive receptor inactivation or activation
- An overview of the compartmentalized GPCR Signaling: Relevance and Implications
Towards a molecular understanding of endosomal trafficking by Retromer and Retriever.
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
Orion’s discovery process is that the initial search for potent target receptor modulators is agnostic towards Orion CCL5 superagonist analog significantly increased both the potency and selectivity of the payload towards
