Five scientists audit what AI can and can't do for GPCR drug discovery — from orphan receptors and biased In October 2020, five scientists gathered virtually at the 3rd EARNEST meeting to debate a question that For any scientist whose grant proposal now contains the phrase "machine learning" whether they fully Trained as a mathematician and computer scientist, his doctoral work focused on developing new methods Yaroslav Nikolaev is a scientist at InterAx Biotech with a dual background in biology and computation

Burning Curiosity as the Non-Negotiable Hay's advice to junior scientists distills to a single criterion The scientists who persist, in her framing, are not the ones who feel less pain from those setbacks, It's just not fair on the junior scientists who then follow up on that work to find it can't be repeated Join me and learn more about Debbie’s career and what she learned through her experiences as a scientist Leave a quick review to help more scientists find the show—and help us keep improving every episode.

GPCR Podcast - The Voice of the Community Conversations with the world’s leading GPCR scientists. Exploring discoveries, careers, and ideas shaping human health. Amplify voices – Provide scientists a platform to showcase their work. Yamina Berchiche interviews leading GPCR scientists on this vibrant, entertaining podcast. I really appreciate the way the podcast educates and mentors, particularly towards junior scientists

Sakmar Tom Sakmar is a physician-scientist and professor at Rockefeller University in New York. Khorana’s lab made early key contributions and developed strategies to express, reconstitute and assay Tom’s lab also pioneered the early use of computational homology modeling, molecular dynamics simulations Early applications included “targeted photo-crosslinking,” and more recently, the parallel development Leave a quick review to help more scientists find the show—and help us keep improving every episode.

Michel Bouvier has spent his career building the tools to show why. , and his postdoctoral training with Bob Lefkowitz at Duke University, where he was among the first scientists without sentimentality: research has periods where it is simply difficult, and passion is what carries a scientist Discovering pharmacological chaperones for V2 vasopressin receptor mutations 40:19 Advice for junior scientists Leave a quick review to help more scientists find the show—and help us keep improving every episode.

In 2013, Demet began her independent research career at the University of Chicago within the Department and career paths, with a focus on their experiences in academia. GPCR Field Progress and Advice for Junior Scientists Demet and Yamina discussed the progress of their Yamina expressed her love for the GPCR field and asked for advice for junior scientists interested in Leave a quick review to help more scientists find the show—and help us keep improving every episode.

Host Yamina Berchiche sets a welcoming tone as they dive into Ian’s unique academic journey—from early His story offers valuable insights for anyone navigating the path from student to scientist. discusses how his experiences at the University of Chicago and the University of Michigan shaped his scientific This episode is both educational and inspiring, offering a behind-the-scenes look at a rising scientist Leave a quick review to help more scientists find the show—and help us keep improving every episode.

Academia, Career Journeys, and Advice Yamina and Claudia discussed Claudia's career journey in academia Yamina highlighted the challenges of career choices, especially when family situations are involved. Claudia also mentioned the significant experiences that shaped her career trajectory, such as her time Towards the end, Claudia offered advice to junior scientists, suggesting that they explore different Leave a quick review to help more scientists find the show—and help us keep improving every episode.

GPCR Ecosystem: uniting scientists, biotech, and innovators to advance GPCR research worldwide. Who We Are We are a global network of scientists, biotech innovators, pharma professionals, CRO leaders 50+ Biotech Companies Built by Scientists. Now, it's a global ecosystem of scientists, biotech teams, CRO leaders, and trainees working to move Premium Members Include: ✔ Drug hunters at early-stage biotechs ✔ CRO leaders building assays and tools

Explore the fascinating career journeys, groundbreaking discoveries, and impactful contributions of experts GPCR Podcast features leading scientists, innovators, and biotech professionals whose work is advancing with experts Provide researchers with a different outlet to make their work known and Inspire young scientists to work on GPCRs It’s been a privilege to chat with so many GPCR scientists since 2020. Brian Kobilka, and many other amazing scientists. What is the format of the Dr.GPCR Podcast?

Human ortholog connections, from fly adhesion GPCRs to vertebrate vascular and neurological disease Career decisions in academic science, uncertainty, reentry, and the conditions that keep scientists in the : GeneTex and Eurofins DiscoverX 00:29 - Introduction of Beatriz Blanco-Redondo; icebreaker 01:15 - Career turning points; uncertainty on returning from the US 33:25 - Advice for scientists working on adhesion Leave a quick review to help more scientists find the show—and help us keep improving every episode.

An authoritative and prolific scientist, with over 650 scientific publications, he is most beloved as a mentor and his relentless encouragement that shaped the careers of hundreds of scientists worldwide Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

With a career spanning two decades at the intersection of fluorescence chemistry, functional assays, and product development, Eric takes us through the highs, failures, and scientific “aha” moments that With a foundational career at Cisbio Bioassays—later acquired by Revvity—Eric played a pivotal role in access to GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research or career Leave a quick review to help more scientists find the show—and help us keep improving every episode.

An authoritative and prolific scientist, with over 650 scientific publications, he is most beloved as a mentor and his relentless encouragement that shaped the careers of hundreds of scientists worldwide Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

An authoritative and prolific scientist, with over 650 scientific publications, he is most beloved as a mentor and his relentless encouragement that shaped the careers of hundreds of scientists worldwide Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

drug discovery moved from a stubborn crystallography problem to a generative platform — through the career of a scientist who helped engineer that shift. One of her career path-defining moments came when she visited Dr. Chris Tate and Dr. Join me and learn more about her fascinating career trajectory. Dr. Leave a quick review to help more scientists find the show—and help us keep improving every episode.

Hebert's advice to young scientists: embrace the complexity that intimidates your mentors. His own career was shaped by serendipitous observations — GPCR dimers that no one expected, negative engagement 22:44 Intracellular GPCRs — drugging receptors on the nuclear membrane 26:21 Advice to young scientists — the unexpected result that redirected the project 27:49 Three aha moments that reshaped a career: Leave a quick review to help more scientists find the show—and help us keep improving every episode.

He began his scientific career studying adenosine receptor signaling during a PhD with Bertil Fredholm questions could be asked Working in cells that endogenously express multiple frizzled subtypes makes it nearly may not reflect the final edited video exactly. 00:00 Introduction 00:48 From Berlin to Stockholm — a career changed everything 53:43 Conformational change as the strongest argument for GPCR identity 01:03:11 Career Leave a quick review to help more scientists find the show—and help us keep improving every episode.

She now works at Gator Bio, where she transitioned from Field Application Scientist - serving as a technical interpretation Equilibrium vs. dynamic frameworks for studying receptor biology The Field Application Scientist as a career model for GPCR-trained scientists The structural complementarity of academic and industry The Field Application Scientist role is one of the least-known best fits for GPCR-trained scientists Leave a quick review to help more scientists find the show—and help us keep improving every episode.

researchers learn, connect, and advance together — with expert-led courses, live masterclasses, and career courses, live masterclasses, career tools, and the GPCR community. matchmaking 💡 Support open resources for the global GPCR field 🧠 Designed for researchers at every career At less than $10 a week, University gives you live access to leading GPCR scientists, 200+ on-demand "Will this really help my career?" Yes.

Nicki) Perry-Hauser I am a postdoctoral research fellow endeavoring to build a productive, independent scientific research career in adhesion G protein-coupled receptor (aGPCR) biology. Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

spans training in Spain, Belgium, and a postdoctoral fellowship at UC San Diego, where he navigated a career focused on G protein-coupled receptors (GPCRs) while aiming to maintain broad scientific interests. Garcia-Markos reflects on milestones in his research journey, reinforcing the passion that drives scientists Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

From the early days of ion channel chemistry to pioneering peptide–fluorophore conjugates for the GLP Why targeting the pharmacologically relevant surface-exposed receptor pool changes the way scientists Curiosity, collaboration, and a love of translating chemical concepts into biological insight drive his scientific Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

directors of the San Diego Entrepreneurs Exchange, a nonprofit organization that provides resources for early-stage Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

discovery chaos into clarity—Yamina’s Corner offers expert GPCR strategy, CRO guidance, and tailored scientific Home About News Get in Touch Welcome Turn GPCR Chaos Into Insights Expert strategic and scientific consultancy Biotech innovators, VC investors and CRO partners Biotech Pipeline Acceleration For Biotech Leaders & Scientists This ensures robust, defensible decisions that de-risk your program from early discovery to regulatory Murat Tunaboylu, CEO Antiverse Before engaging Yamina, our team faced hurdles navigating complex early

Antony Boucard - the scientist who discovered that a cell adhesion molecule and a GPCR share a black He nearly discarded the sample. there — outcomes shaped as much by openness as by design — has followed him through every phase of his career dream tool — a nanoscale camera navigating the cell surface in real time 01:22:24 Advice to junior scientists Leave a quick review to help more scientists find the show—and help us keep improving every episode.

Stroke Foundation of Canada MacDonald Scholar (1998-2003) and Heart and Stroke Foundation of Ontario Career His research career has focused on the investigation of the regulation of G protein-coupled receptors Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

Stroke Foundation of Canada MacDonald Scholar (1998-2003) and Heart and Stroke Foundation of Ontario Career His research career has focused on the investigation of the regulation of G protein-coupled receptors Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

I then started my career at Evotec before moving to Domain Therapeutics (called Faust pharmaceutical Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.

Caron has received numerous awards including a Burroughs Wellcome Fund Career Award in the Biomedical Caron currently holds multiple scientific advisory roles in academia, industry and the National Institutes Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses ✔ Scientific Leave a quick review to help more scientists find the show—and help us keep improving every episode.