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Results found for "positive allosteric modulators"
- Partners Submition Form | Dr. GPCR Ecosystem
GPCR Ecosystem and collaborate with us to make a positive impact.
- Game-changer for GPCR research! 🔬🧪 Molecular glues offer a new way to fine-tune receptor signaling, opening doors for next-gen drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/reviews/molecular-glues%3A-a-new-approach-to-modulating-gpcr-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/reviews/molecular-glues%3A-a-new-approach-to-modulating-gpcr-signaling-bias delivered to your inbox ➡️ https:// www.ecosystem.drgpcr.com/reviews/molecular-glues%3A-a-new-approach-to-modulating-gpcr-signaling-bias
- Dr. John Janetzko | Dr. GPCR Ecosystem
The conversation also touched on the challenges of applying for academic positions in the US, the importance Next steps • Yamina will share ideas on supporting John's new academic position after the recording stops John shared his experience of reaching out to and securing a position in Brian's lab. Academic Position Applications and Transition Preparation John and Yamina discussed the extensive process of applying for academic positions in the US.
- Anything BUT GPCRs with Dr. Mikel Garcia-Marcos | Dr. GPCR Ecosystem
(biochemistry, cell biology, genetics) and experimental systems (purified proteins, cultured cells, model from postdoctoral research to leading his own lab, addressing the challenges of applying for academic positions
- irreversible drugs post 3 | Dr. GPCR Ecosystem
Home → Flash News → irreversible drugs post 3 Irreversible kinetics = strategic lever in drug design. Inside Terry’s Corner, you’ll gain access to focused, high-impact modules built for teams who need to
- ep 169 with sokhom pin some 3 | Dr. GPCR Ecosystem
Positioning. 🎧 Hear about the journey: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-169-with-dr-sokhom-pin
- Dr. Aurélien Rizk | Dr. GPCR Ecosystem
Before focusing on the development of innovative mathematical modeling and simulation methods for drug Integrating Mathematical Models and Biology: A Fascinating Discussion Yamina and Aurelien Rizk had a conversation about the importance of merging mathematical models and biology. the strategic importance of planning in the biotech sector due to limited funds and the need to show positive and relevance of mathematical models in systems biology and pharmacology.
- Dr. Tobi Langenhan | Dr. GPCR Ecosystem
I work with invertebrate animal models (mainly D. melanogaster) and in vitro techniques to pick apart adhesion GPCRs, and extends to the development of novel screening approaches to identify pharmacological modulators
- Dr. Nariman Balenga | Dr. GPCR Ecosystem
the role of RGS4 and RGS5 in airway hyperresponsiveness and lung fibrosis in acute and chronic mouse models A fungal serine protease allergen with GPCR-modulating features was discovered as a new biomarker and
- GPCRs and the Science Behind Pain and Recovery with Dr. Alex Serafini | Dr. GPCR Ecosystem
Alex Serafini shares why pain research must start with real-world behavior and models before drilling with RNA-seq and behavioral analysis, revealed nuanced roles of RGS4, RGS9, and RGSZ — not just as modulators Research Playbook Looking ahead, Serafini’s vision is bold: build a lab that develops translational models He's equally focused on sex differences in pain processing and the failure of "one-size-fits-all" models He aspires to become a physician-scientist, with a focus on translational in vitro and in vivo model
- Dr. Josephine (Pina) Cardarelli | Dr. GPCR Ecosystem
Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers Prior to this, she held the position of Vice President, at Medarex, Inc .
- irreversible drugs post 1 | Dr. GPCR Ecosystem
Home → Flash News → irreversible drugs post 1 Irreversible Drugs – Trailer Published on October 21, 2025
- Eleonora Comeo | Dr. GPCR Ecosystem
We sat down to chat about GPCRs, synthesizing labeled ligands, and her unique position that allows her
- Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of the Dr.GPCR Podcast,. The catch? It’s all about understanding the system, not replacing it. From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲 Watch now: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲 From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲
- Lauren Celano | Dr. GPCR Ecosystem
Lauren has a science background and is passionate about helping talented scientists find their dream position
- New cryo-EM insights reveal how extracellular domains communicate with transmembrane regions in holo-adhesion GPCRs, uncovering mechanisms behind receptor activation. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function #gpcr #drgpcr | Dr. GPCR Ecosystem
www.ecosystem.drgpcr.com/adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function www.ecosystem.drgpcr.com/adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function
- Dr. Christel Menet | Dr. GPCR Ecosystem
became head of medicinal chemistry. 6 years ago I decided to take on a new challenge by taking the position
- CRO Advisory | Dr. GPCR Ecosystem
accelerate go/no-go calls & shorten timelines Your Science Stays Focused on What Matters We work together to position your CRO for growth • Refine your offering to match what biotech teams actually need • Position your
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Determine the Signaling Profile of Adhesion GPCR ADGRL1 / Latrophilin-1 Sheila Ribalta-Mena GPR110 modulates During my graduate studies, using various transgenic mouse models and expertise in intestinal and renal antibodies, and cancer-associated mutations at the GAIN-7TM interface, alter holoreceptor conformations, and modulate single-molecule perspective and investigating how the binding of extracellular transsynaptic ligands modulates " Cell Biology PhD student " Sheila Ribalta-Mena on the web CINVESTAV ResearchGate LinkedIn GPR110 modulates
- Custom Molecules, Fluorescent Probes: When Chemists Think Like Biologists with Dr. Maria Majellaro from Celtarys | Dr. GPCR Ecosystem
But we had to learn everything else—IP, market positioning, customer discovery.” — Maria Majellaro This scientific expertise is rooted in organic synthesis and medicinal chemistry, with a particular focus on GPCR modulators
- terrys corner model drug response | Dr. GPCR Ecosystem
Home → Flash News → terrys corner model drug response Published on July 10, 2025 Category Terry's Corner In Terry’s Corner latest lesson, discover how pharmacologic models do just that. From historical linkage theory to dynamic probability models, the comparison of data to theory will be discussed. 🟢 Read the full breakdown: ✳️ https://www.ecosystem.drgpcr.com/post/what-if-you-could-predict-drug-behavior-with-just-a-snapshot
- Vaithish Velazhahan | Dr. GPCR Ecosystem
been elected a Research Fellow at Gonville and Caius College, which is one of the most prestigious positions
- ama session sept 18 post 3 | Dr. GPCR Ecosystem
Home → Flash News → ama session sept 18 post 3 “Technologies come and go.
- Dr. Brian Arey | Dr. GPCR Ecosystem
He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility
- Dr. Brian Arey | Dr. GPCR Ecosystem
He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility
- Biased agonism at the GLP-1 receptor: from structure to animal models of disease
GPCR Retreat Program < Back to schedule Biased agonism at the GLP-1 receptor: from structure to animal models
- Scaling GLP 1 Receptor Tools Through Academia Industry Collaboration | Dr. GPCR Ecosystem
validation in GPCR assay design Building reagents that must work in complex tissues, not just simplified models Her work centers on GPCR modulators, synthetic chemistry, and enabling robust biological assays through
- Dr. Stuart Maudsley | Dr. GPCR Ecosystem
To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology
- Dr. Bruno Giros | Dr. GPCR Ecosystem
Bruno Giros has trained 59 master's, doctoral and postdoc students, most of his trainees obtain positions
- Dr. Stuart Maudsley | Dr. GPCR Ecosystem
To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology




















