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- Did you know that GPR180 helps regulate lipid metabolism and may play a role in preventing obesity? recent study shows that overexpression of GPR180 in adipose tissue improves lipid metabolism and protects against HFD-induced obesity, while its knockout worsens lipid accumulation. This finding highlights GPR180 as a potential therapeutic target for metabolic disorders! Catch up on this exciting research in the Ecosystem today! 🏆📖 You’ll need to register, but don’t worry—it’s free! ➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes #gpcr #drgpcr #metabolism #obesity | Dr. GPCR Ecosystem
Catch up on this exciting research in the Ecosystem today! Catch up on this exciting research in the Ecosystem today!
- New strategic partnership alert! 🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research. Get custom, fast, and functional ligands backed by real scientists solving real assay problems. 🧪 “We don’t just deliver compounds. We solve assay problems.” – Dr. Maria Majellaro, CSO, Celtarys Listen to Ep. 168 now and meet your new assay partner 😉 ✳️ https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarys #GPCRdrugDiscovery #FluorescentLigands #DrGPCR #BiotechTools #AssayDevelopment | Dr. GPCR Ecosystem
🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research 🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research
- Ever wondered how we perceive bitterness? 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor, bound to the drug flufenamic acid (FFA) and its signaling partner gustducin! 🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound design. 🧪✨ Learn more about this exciting breakthrough in bitter taste signaling. | Dr. GPCR Ecosystem
👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14 , the most promiscuous bitter taste receptor
- What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment? That’s precisely what Dr. Kotliar from the Sakmar lab made possible! In Ep.167 of the Dr. GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research community. ✳️ Listen to the episode: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast | Dr. GPCR Ecosystem
interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research
- A new study from the Hudson Lab at the University of Glasgow shows that the FFA receptor antagonist AH7614 is actually an inverse agonist - suppressing fat cell formation, boosting lipolysis and reducing glucose uptake. Explore how targeting FFA4 could help fight metabolic disorders. Catch up with the latest research conducted in the Hudson lab in Ep. 161 of the Dr. GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/inverse-agonism-of-the-ffa4-free-fatty-acid-receptor-controls-both-adipogenesis-and-mature-adipocyte-function #GPCR #drGPCR #FFA4 #metabolism #adipocytes” | Dr. GPCR Ecosystem
Catch up with the latest research conducted in the Hudson lab in Ep. 161 of the Dr. GPCR Podcast. Catch up with the latest research conducted in the Hudson lab in Ep. 161 of the Dr. GPCR Podcast.
- Think βCGRP is just αCGRP’s understudy? Think again. New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor family, challenging the long-held assumption of redundancy. 🔬 A closer look reveals differences in G protein coupling, second messenger production, and receptor trafficking. 📊 This could reshape how we understand CGRP-related physiology—and how we target it in drug design. 🧠 Pain, inflammation, metabolism: the implications go far beyond signaling bias. 🔗 Read the full paper in Biochemistry: Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR #CGRP #DrugDiscovery #Pharmacology #SignalTransduction #Neuropeptides | Dr. GPCR Ecosystem
New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor
- Dr. Robert F. Bruns | Dr. GPCR Ecosystem
Bruns on the web ResearchGate LinkedIn Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Guillaume Sandoz's group in 2019 as a postdoctoral research scientist at Université Côte d‘Azur, France Sabbagh led research projects aimed on drug discovery of small molecules for the treatment of inflammatory Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC Montréal, Montreal, Quebec, Canada " About Ana Lilia Moreno Salinas "I am currently part of a dynamic research Our research aims to leverage this knowledge to identify novel pharmacological targets and contribute
- Illuminating Functional Selectivity and Allosterism at GPCRs.
Stéphane Laporte is a Professor of Medicine, and the Director of Research of the Division of Endocrinology He has received many awards, including a Canada Research Chair, FRSQ scholarships and the CDA/CSEM/Merck His expertise is in molecular pharmacology and his research program focuses on the molecular and cellular His research program also studies the allosteric, biased signalling regulation of GPCR and has contributed The Canadian Institutes for Health Research and March of Dimes currently support his research."
- Nicole Perry-Hauser | Dr. GPCR Ecosystem
Podcast Strategic Partners Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I am a postdoctoral research fellow endeavoring to build a productive, independent scientific research career in adhesion G protein-coupled My long-term research interests involve resolving signaling pathways downstream of aGPCRs and establishing Nicole (Nicki) Perry-Hauser on the web LinkedIn Research Gate Pubmed Dr. How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- GPCR Weekly News | Dr. GPCR Ecosystem
Stay ahead with the latest research breakthroughs, industry updates, job opportunities, and upcoming GPCR Weekly News - Your Hub for GPCR Research, Industry Updates, Jobs & Events Delivered straight to Latest Research Breakthrough discoveries, new publications, and cutting-edge GPCR research insights. of what you'll find in our latest newsletter How Schild Analysis Protects Your Conclusions in GPCR Research Valid until canceled Join Premium Now 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research
- Media Partner Packages | Dr. GPCR Ecosystem
Elevate Your GPCR Focused Company Visibility Reach 1300+ GPCR researchers. Connect With The GPCR Community You've built incredible tools, services, or platforms for GPCR researchers As a media partner, you'll gain trusted access to an engaged audience of academic researchers, biotech Build Trust Develop content that speaks their language and establishes your credibility in the GPCR research Join these leading organizations in the GPCR research ecosystem Book Book a 30-minute Strategy Call
- University Pricing | Dr. GPCR Ecosystem
All these benefits are designed to enhance your research experience and keep you informed about the latest Accelerate Your GPCR Research Join a global community of scientists transforming how GPCR discoveries One insight, one connection, one ‘aha’ moment — can save months of research time. opportunities, and tools to accelerate GPCR-related research and career growth. Ready to Advance Your GPCR Research?
- Dr. Gunnar Schulte | Dr. GPCR Ecosystem
Gunnar Schulte Gunnar Schulte is a Professor in receptor pharmacology and research group leader for the Gunnar Schulte is also the scientific secretary of the Swedish Society for Medical Research (SSMF) and General Research Interest: The focus in the Schulte lab is on Frizzled signaling and pharmacology aiming Most importantly my research team tries to understand underlying mechanisms of WNT-receptor interaction How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Dr. Patrick Sexton | Dr. GPCR Ecosystem
Patrick Sexton Patrick Sexton is a Professor of Pharmacology, National Health and Medical Research Council of Australia Senior Principal Research Fellow, and Director of the Australian Research Council Centre He is a 2021 Clarivate Analytics Highly Cited Researcher in two disciplines: Pharmacology & Toxicology Society), Vane Medal (BPS), Gordon Hammes Lectureship Award (American Chemical Society) and the GSK Research How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Dr. Stephane Angers | Dr. GPCR Ecosystem
Angers established his independent research program in the Department of Pharmaceutical Sciences at the He is the recipient of the Canada Research Chair in Functional Architecture of Signal Transduction. His research program is developed to understand the signaling mechanisms underlying the Wnt and Hedgehog Angers was named Director of the Donnelly Centre of Cellular and Biomolecular Research at the University of Toronto, an internationally recognized Research Institute bringing together multidisciplinary teams
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
New York State Psychiatric Institute, Research Foundation for Mental Hygiene, New York, USA. In 2013, Demet began her independent research career at the University of Chicago within the Department Tall Department of Pharmacology, University of Michigan "" About Frank Kwarcinski "I am research faculty Gregory Tall and our research primarily focuses on the structural and biochemical characterization of Sun as a postdoc/research associate/assistant professor.
- Dr. Mark Connor | Dr. GPCR Ecosystem
Grant-funded independent research positions from 2001 at University of Sydney (opioids and sensory neurons Institute Portland (visiting scientist with Ed McCleskey, sensory neuron properties); Pain Management Research Institute (more opioids, cannabinoids and T-type Ca channels) and Brain and Mind Research Institute Mark Connor on the web Researchers Twitter Google Scholar Dr. GPCR Ecosystem Enjoying the Dr. How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
His research focuses on novel paradigms of drug action at GPCRs, particularly allosteric modulation and Since 2014, Clarivate Analytics have annually named him a Highly Cited Researcher in ‘Pharmacology & Toxicology’, and in 2021 also named him a Highly Cited Researcher in the additional category of ‘Biology GPCR researchers in Australia and the initiation of a successful series of conferences. and its capacity to translate research into therapeutic commercialization.
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
His research focuses on novel paradigms of drug action at GPCRs, particularly allosteric modulation and Since 2014, Clarivate Analytics have annually named him a Highly Cited Researcher in ‘Pharmacology & Toxicology’, and in 2021 also named him a Highly Cited Researcher in the additional category of ‘Biology GPCR researchers in Australia and the initiation of a successful series of conferences. and its capacity to translate research into therapeutic commercialization.
- Dr. Lauren M. Slosky | Dr. GPCR Ecosystem
Addiction, a multidisciplinary initiative within the University of Minnesota’s Medical School to advance research Slosky’s research is focused on understanding how neuropeptide G protein-coupled receptors (GPCRs) regulate Slosky’s work has been recognized through several travel and research awards, including the William James In addition to research, Dr. Slosky on the web Twitter University of Minnesota Department Page LinkedIn Google Scholar PubMed Research
- Dr. Michael Feigin | Dr. GPCR Ecosystem
at Cold Spring Harbor Laboratory and probed the roles of polarity proteins (Feigin, et al., Cancer Research Quick recap Yamina and Mike engaged in a conversation about their scientific research experiences. The conversation also highlighted the importance of resilience and creativity in scientific research. Mike's Research on Cell Polarity and GPCRs in Cancer Mike shared his research on cell polarity and its Cytokine Inhibition, Collaboration, and Anti-Anxiety Drug Research Mike discussed the ongoing research
- Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
GPCR Ecosystem and beyond About Monserrat Avila Zozaya "My doctoral research was focused on investigating I am currently a postdoctoral researcher fellow in Dr. Kathleen Caron's laboratory at UNC. My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic
- Dr. Ralf Jockers | Dr. GPCR Ecosystem
He is the Research director at INSERM with a specific interest in G protein-coupled receptors by developing He was the director of the French network of GPCRs (GDR-3545), currently directs the International Research receptor » sub-committee, Editor-in-Chief of « Frontiers in Cellular Endocrinology » and AE of « J Pineal Research He is a highly cited researcher – 2019 and 2020 identified by Clarivate Web of Science ™. Dr. How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Dr. Nyla Naim, Dr. Michael Lemieux & Dr. Jason Nasse | Dr. GPCR Ecosystem
She received her Ph.D. at the University of Pittsburgh and continued her postdoctoral research at the Nyla supports biomedical research by connecting researchers with resources and promoting reproducible Prior to his role at Addgene, Jason held roles in academia, big pharma, and non-profit research organizations How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Signals, pH, and Discovery : Cracking GPCR Mysteries with Dr. Ian Chronis | Dr. GPCR Ecosystem
unique academic journey—from early interests in medicine to his pivot toward pharmacology and GPCR research His research centers on the beta-2 adrenergic receptor and GPR65 , a proton-sensing receptor with promising better experimental tools in GPCR signaling , and the importance of engaging with the broader GPCR research offering a behind-the-scenes look at a rising scientist’s journey in the ever-evolving world of GPCR research My research has looked at the trafficking and signaling of adrenergic and proton-sensing receptors, with
- A journey from Duke to McGill along the dopamine circuit
University in Paris and a short internship at Genentech Inc. in South San Francisco, he joined the CNRS as a Research Since 2008, he arrived at McGill University with a Canada Research Chair. At McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to Brunos Giros on the web The Douglas Research Centre McGill University Pubmed Google Scholar LinkedIn
- Dr. Prasenjit Saha | Dr. GPCR Ecosystem
Prasenjit Saha I conducted my doctoral research at the Indian Institute of Science, Bangalore, India, My research goal is to identify novel cellular target receptors of human gut microbe-derived metabolites During my post-doctoral research, I was part of a study that identified the receptors of a novel human My long-term plan is to conduct research in the field of receptor biology, with a focus on GPCRs. How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Anything BUT GPCRs with Dr. Mikel Garcia-Marcos | Dr. GPCR Ecosystem
My research aims to understand the mechanisms and consequences cell communication via heterotrimeric Garcia-Marcos shares insights on transitioning from postdoctoral research to leading his own lab, addressing positions and the importance of networking, adaptability, and mentorship in fostering a collaborative research Garcia-Markos reflects on milestones in his research journey, reinforcing the passion that drives scientists How GPCR Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Trainee Symposium II
am currently a Ph.D. student at the Schulich School of Medicine and Dentistry, Western University, researching I got my Bachelor's in Pharmacy from Minia University in 2011 and began my career as a teaching and research During my short academic journey, I was awarded the Young Investigator Transdisciplinary Research Award Currently, I am engaged in postdoctoral research in the laboratory of Dr. Scott Prosser. My primary research focus lies in gaining deeper insights into the structural mechanisms governing G



















