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therapeutics need a reliable, comprehensive partner that spans discovery, optimization, and regulatory submission These industry-standard assays, designed for regulatory submissions, are backed by partnerships with of Agonist Access White Paper Find Your Solution The Human GPCRome Obtain Wall Poster Shop Products Supporting Obesity and Diabetes Research Eurofins DiscoverX supports the ongoing obesity/diabetes revolution with

episode: Chemical probes vs antibodies: specificity, stability, and live-cell performance Mapping GPCR surface

biotechs—typically preclinical through IND-enabling—who need strategic clarity and hands-on discovery support Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution

International Research Network (IRN) i-GPCRnet of the CNRS, is chair of IUPHAR « Melatonin receptor » sub-committee

And while users aren’t asking for xylazine, dealers are lacing it into the supply—driving overdose deaths

signaling pathways that operate within the primary cilium, a tiny antenna-shaped structure at the cell surface

He has received substantial, long-term support from international and national competitive, charitable GPCR AI Summary Quick recap Yamina and Arthur discussed Arthur's career journey in pharmacology, including Summary Arthur's Career Journey and Allosteric Receptors Yamina and Arthur discussed Arthur's career For their upcoming project, Yamina favored a conversational approach, while Arthur suggested a kickoff They highlighted the importance of fine-tuning the approach to suit different diseases and interdisciplinary

Originally trained as a Veterinary Surgeon , he completed postdoctoral research at the CNRS in Montpellier

Terry Kenakin with short videos, clear summaries, and curated references. Also in this week’s Dr. structures reveal Gq bias mechanisms ♦️ NMBR simulations uncover new activation pathways ♦️ Axcelead & Superluminal

undergraduate degree at the University of Cambridge, Nick carried out his Ph.D. at King’s College London, supported It was these studies and subsequent postdoctoral work that led to Nick's interest in peptide messengers

arrestins and post-translational modifications (PTMs), such as phosphorylation, ubiquitination, and SUMOylation reveal the spatial and temporal requirements for GPCR activation of signaling pathways related to cell survival

identifying ligands for orphan GPCRs by developing a powerful new computational tool for identifying ‘surrogate

Since 2013, he has been elected Chair of the subcommittee for the Dopamine receptors of the International

Strong education with a Doctor of Philosophy (Ph.D.) in biochemistry under the supervision of Michel

uncompetitive), the messy truth of CYP450 allostery and DDIs, and why allosteric control can protect potency in substrate-rich

Ilana graduated Summa cum laude from Cornell University, where she studied Chemistry and Chemical Biology

Her subsequent work has focused on understanding the role of compartmentalized Gq signaling by the cytomegalovirus-encoded

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Meet the sponsors who make the Adhesion GPCR Workshop 2024 possible, supporting global collaboration Up Abstract Submission Submit your research abstracts following our guidelines to present at the conference

companies that want to: Make their services or products easily discoverable within the GPCR ecosystem Support clear, structured product and service offerings in one trusted location Use ecosystem visibility to support These channels are used to support discovery and evaluation — helping teams understand what you offer

This technology supports robust analysis even at low endogenous receptor expression levels. Suitable for basal/constitutive and agonist-induced GPCR internalization Compatible with TRF plate readers address unmodified receptors in primary cells View Product The Fab Anti-Mouse IgG2 Eu-conjugate is suited ✅ Comprehensive validation: validated for GPCRs, but also antibodies and ADCs. ✅ Versatility across suspension Revvity offers a comprehensive reagent portfolio to match that complexity—supporting every stage of the

We designed the Ecosystem to support your work —no matter where you are in your GPCR journey. Episode Launched our podcast to share expert insights with the scientific community. 2021 2nd Annual Summit

That's where I come in : to pressure-test the science, align the strategy, and make sure every experiment Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution

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chaos into clarity—Yamina’s Corner offers expert GPCR strategy, CRO guidance, and tailored scientific support Book My Consultation Critical Bottlenecks in Your GPCR Pipeline ❌ Overwhelming pharmacology Data ❌ Suboptimal Partnerships ❌ Stalled Pipeline Progression ❌ Uncertainty in GPCR Investments Advisory Focus Areas Expert support Power Discovery How We Work: Your Path to GPCR Success 1 Initial Strategic Alignment We begin with a Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution

Later, I completed my Master's degree in Pharmacology at Minia University, focusing on hydrogen sulfide's

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These receptors belong to the super-family of G-protein coupled receptors (GPCR), the major molecular The Beaulieu group is presently investigating how cell surface express proteins can act as allosteric