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the Web Radcliffe Department of Medicine Islet Biology Lab University of Birmingham Unlock the Full Dr discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Enjoying the Dr

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Minor offsets may occur. 00:00 Introduction and Dr. Dr. Elva Zhao on the web LinkedIn Monash University Pubmed Twitter Dr. GPCR Ecosystem Unlock the Full Dr. discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Enjoying the Dr

Drug Discovery Your One-Stop-Shop for End-to-End GPCR Drug Discovery Services Explore capabilities Start Strategies - Webinars Get in touch Talk to the Eurofins Discovery team Reach the group nearest you, or start a conversation through the Dr.

Blanco-Redondo; icebreaker 01:15 - Career path: from Spain to Germany, and the decision to go further 05:57 - Dr Unlock the Full Dr. discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Enjoying the Dr

Explore how GPCR signaling shapes mosquito feeding and mating behaviors with Dr. Laura Duvall. user=Vk3KGSoAAAAJ&hl=en - Lab: https://www.duvalllab.com/ Unlock the Full Dr. discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Enjoying the Dr

Martin Marro Guest Link - LinkedIn: https://www.linkedin.com/in/martinmarro/ Unlock the Full Dr. discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Enjoying the Dr

Unlock the Full Dr. discussions → Become Premium Upcoming Live Expert Sessions ➚ 🔒Explore the Full Masterclass ➚ Enjoying the Dr

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< Back This is a Title 01 This is placeholder text. To change this content, double-click on the element and click Change Content. This is placeholder text. To change this content, double-click on the element and click Change Content. Want to view and manage all your collections? Click on the Content Manager button in the Add panel on the left. Here, you can make changes to your content, add new fields, create dynamic pages and more. You can create as many collections as you need. Your collection is already set up for you with fields and content. Add your own, or import content from a CSV file. Add fields for any type of content you want to display, such as rich text, images, videos and more. You can also collect and store information from your site visitors using input elements like custom forms and fields. Be sure to click Sync after making changes in a collection, so visitors can see your newest content on your live site. Preview your site to check that all your elements are displaying content from the right collection fields. Previous Next Articles News Get in Touch Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About

< Back This is a Title 02 This is placeholder text. To change this content, double-click on the element and click Change Content. This is placeholder text. To change this content, double-click on the element and click Change Content. Want to view and manage all your collections? Click on the Content Manager button in the Add panel on the left. Here, you can make changes to your content, add new fields, create dynamic pages and more. You can create as many collections as you need. Your collection is already set up for you with fields and content. Add your own, or import content from a CSV file. Add fields for any type of content you want to display, such as rich text, images, videos and more. You can also collect and store information from your site visitors using input elements like custom forms and fields. Be sure to click Sync after making changes in a collection, so visitors can see your newest content on your live site. Preview your site to check that all your elements are displaying content from the right collection fields. Previous Next Articles News Get in Touch Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About

< Back This is a Title 03 This is placeholder text. To change this content, double-click on the element and click Change Content. This is placeholder text. To change this content, double-click on the element and click Change Content. Want to view and manage all your collections? Click on the Content Manager button in the Add panel on the left. Here, you can make changes to your content, add new fields, create dynamic pages and more. You can create as many collections as you need. Your collection is already set up for you with fields and content. Add your own, or import content from a CSV file. Add fields for any type of content you want to display, such as rich text, images, videos and more. You can also collect and store information from your site visitors using input elements like custom forms and fields. Be sure to click Sync after making changes in a collection, so visitors can see your newest content on your live site. Preview your site to check that all your elements are displaying content from the right collection fields. Previous Next Articles News Get in Touch Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About Menu • Home • Services • About

Conformational biosensors for GPCR activation: FRET, BRET, and single-color sensor design, site-specific labeling, and applications in drug discovery. < Back to Courses Conformational Biosensors for GPCR Activation December 10, 2026 10 AM - 11:30 AM EST 🔒 Watch Recordings - Join Premium Access the full library of recorded Masterclass sessions. Get Live Updates Be notified when new live Masterclasses are scheduled. Introduction Conformational biosensors report the structural rearrangements of a GPCR as they happen in living cells, upstream of any signaling readout. This Masterclass covers the principles of FRET, BRET, and single-color conformational biosensors, from the development of resonance energy transfer methods to fluorophore selection, sensor architecture, and optimization for sensitivity and specificity. It then compares site-specific fluorescence labeling strategies, their common pitfalls, and how to evaluate labeling efficiency. Coverage extends to the fluorescence spectroscopy and microscopy methods that read these sensors, published case studies on receptor activation and signaling, and applications in mechanism-of-action studies, ligand profiling, target validation, and high-throughput screening. Intended for scientists with a working knowledge of GPCR pharmacology who use, or plan to build, cell-based activation assays. Instructors Katarina Nemec Katarina Nemec works at the intersection of GPCR molecular pharmacology, biosensor design, high-throughput screening, and data-driven drug discovery. She recently joined the High Throughput Biology team at Boehringer Ingelheim, where she supports the advancement of pipeline candidates. Trained as a pharmacist, she earned her doctorate in Biomedicine in Martin Lohse's laboratory, where she designed conformational biosensors to study GPCR activation and signaling dynamics and showed how RAMP proteins modulate PTH1R pharmacology. As a Scientist in Madan Babu's lab at St. Jude Children's Research Hospital, she developed multiplexed screening approaches and studied the developmental expression dynamics of GPCRs. In this Masterclass she brings biosensor design and its translation to screening and drug discovery. Romy Thomas Romy Thomas studies how GPCRs activate, how they select their G proteins, and how ligands shape signaling, combining live-cell approaches with in vitro biochemical methods. She is a postdoctoral researcher in Brian Kobilka's lab at Stanford University. She engineers GPCR biosensors and uses fluorescence spectroscopy to follow receptor dynamics and signaling in intact cells. She is first author of a 2026 Nature study that used genetic code expansion and bioorthogonal labeling to build a panel of single-color biosensors for the M2 muscarinic receptor. In this Masterclass she brings site-specific labeling and the spectroscopy methods that read GPCR activation in living cells. 🔒 Watch Recordings - Join Premium Access the full library of recorded Masterclass sessions. Get Live Updates Be notified when new live Masterclasses are scheduled.

Dr. Dr. Yamina Berchiche Dr. What Scientists Are Saying Dr. Hoare is very experienced in the field. I will keep Dr. I wish Dr.

🎓 Kicking Off Today: Dr. any particular topic. 🗓️ Upcoming 4-Week Course: Development of GPCR Ligands as Therapeutic Drugs starting Watch Dr. Kenakin as he introduces the key concepts of this brand-new course.

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The Practical Assessment of Signaling Bias Dr. Terry Kenakin < Back Workshop Summary Join Dr. Dr. Dr. Dr. Terry Kenakin’s workshop offers a fresh perspective on drug discovery .

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