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PM Title: Linking Proteinase Activated Receptor (PAR) Cleavage to Osteoarthritis (OA) Severity About Amr Mousa "I am currently a Ph.D. student at the Schulich School of Medicine and Dentistry, Western University Amr Mousa on the web Google Scholar Dr. GPCR Title: Development of a Transgenic Mouse Platform for the Detection of Endogenous G protein Activity

of GPR56 in the collecting duct, we generated a collecting duct-specific GPR56 knockout (GPR56CD-KO) mouse This mouse model will be useful to delineate the collecting duct-specific role of GPR56 for renal function During my graduate studies, using various transgenic mouse models and expertise in intestinal and renal We found an interaction between BAI3 and MAGI3 in mouse brain lysates. This study aimed to understand the effects of GPR110 on mouse behaviors in relation to neurodevelopmental

behavioral assays, autoradiography, stereotaxic surgeries, electroencephalography, immunohistochemistry, mouse

Rashed Rezwan Parag Identification of Differentially Expressed Gpr116 (Adgrf5) Transcript Variants in Mouse To test this, an LFS mouse model (germline Tp53 deletion) with a second floxed allele under the control Preliminary findings indicate that the simultaneous loss of Bai3 and Tp53 expression in our mouse model A mouse model of Zhu-Tokita-Takenouchi-Kim syndrome reveals indispensable SON functions in organ development Two major types of mRNAs were identified in human/mouse brain, those with a start codon in exon 2 encoding

These drugs were shown to be very effective to rescue the cell death observed in a mouse model of Huntington

laboratory is to understand the physiological consequences of NMDA receptor deficiency using genetic mouse

His laboratory uses knock-out and transgenic mouse models, along with different cell culture systems,

steroidogenesis in regulating sexual determination and adrenal and gonadal development using genetic mouse

characterized the role of RGS4 and RGS5 in airway hyperresponsiveness and lung fibrosis in acute and chronic mouse

protein signaling roles of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse protein signaling roles of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse We utilize several genetically modified mouse models to investigate requirements for receptor activator

protein signaling roles of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse Therapy Hailey Steichen Identification of Differentially Expressed Gpr116 (Adgrf5) Transcript Variants in Mouse Holo-Adhesion GPCR Yuling Feng Localization of putative ligands for adhesion G protein-coupled receptors in mouse

steroidogenesis in regulating sexual determination and adrenal and gonadal development using genetic mouse

Cancer Research, 2014) and GPCRs (Feigin, et al., PNAS, 2014) in breast cancer pathogenesis, using mouse young age and his desire to gain more knowledge about cancer biology led him to transition into using mouse Yamina proposed further exploration of dosage and length of treatment in a mouse model and suggested

sequence with a pHSense probe to monitor their internalization View Product pHSense Fab Anti-Human or Anti-Mouse with a neutral anti-GPCR to address unmodified receptors in primary cells View Product The Fab Anti-Mouse IgG2 Eu-conjugate is suited to study mouse biologics targeting GPCR and confirm their internalization

enzymology, primary and model cell culture, and transgenic, knockout, knock-in and conditional models of mouse

critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells and mouse

enzymology, primary and model cell culture, and transgenic, knockout, knock-in and conditional models of mouse

enzymology, primary and model cell culture, and transgenic, knockout, knock-in and conditional models of mouse

enzymology, primary and model cell culture, and transgenic, knockout, knock-in and conditional models of mouse

pathways and trafficking Localization of putative ligands for adhesion G protein-coupled receptors in mouse Signalling Pal Kasturi Localization of putative ligands for adhesion G protein-coupled receptors in mouse

GPR110 is highly expressed in mouse and human NPCs and neurons, while its expression was absent in astrocytes

knocking out Ryk, required for Vangl2 function, protected synapses and preserved cognitive function in a mouse

critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells and mouse

steroidogenesis in regulating sexual determination and adrenal and gonadal development using genetic mouse

cell models to determine binding sites and mechanisms of allostery, as well as efficacy studies in mouse