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in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade Elita Yuliantie , Arthur Christopoulos , Patrick M.

This Week’s Highlights: Celebrating Excellence:   Patrick Sexton  and Arthur Christopoulos  Named Among

Arthur Christopoulos is now live, titled "A Brief History of Allosteric Modulators." 

investigation on Molecular insights into G protein coupling specificity at a class A GPCR Jianjun Cao, Arthur Christopoulos, Patrick M.

Krumm  for their excellent study on Molecular glues as potential GPCR therapeutics Sabrina Rahman , Arthur Christopoulos , Christopher Langmead , et al. for their outstanding work on Ligand-directed biased agonism

Burger , Arthur Christopoulos , David M.

significant challenge when it comes to detecting and confirming allosteric behaviors (Keov, Sexton, and Christopoulos orthosteric region, or from selective cooperativity with a particular subtype while excluding others (Christopoulos

Christopoulos, Signalling bias in new drug discovery: detection, quantification and therapeutic impact

., Christopoulos, A., & May, L. T. (2016).

Melancon BJ, Hopkins CR, Wood MR, Emmitte KA, Niswender CM, Christopoulos A, et al. Changeux J-P, Christopoulos A. van der Westhuizen ET, Valant C, Sexton PM, Christopoulos A.

., Christopoulos, A., Felder, C. C., Gmeiner, P., Steyaert, J., Weis, W. I., Garcia, K.

orthosteric region, or from selective cooperativity with a particular subtype while excluding others (Christopoulos

In 1967, the Nobel Prize in Physiology or Medicine was awarded jointly to Ragnar Arthur Granit, Haldan