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- Murat Tunaboylu & Ben Holland | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Murat Tunaboylu & Ben Holland About Murat Tunaboylu "Murat Tunaboylu, GPCR About Ben Holland "Ben gained his masters in Engineering Science from Oxford, taking a specialisation nearly 10 years, applying it to antibody generation, analysis, and property prediction since 2017" Ben
- When to Walk, When to Run: Lessons from the GPCR Trenches with Dr. Ben Clements | Dr. GPCR Ecosystem
GPCR scientist Ben Clements shares how positive allosteric modulators could transform opioid therapy Ben Clements 1. From Aspirations to Application: Ben’s Path into Science Ben shares his winding yet deliberate entry We produce great data, but we also joke around. That’s how we work best.” Ben Clements on the web University of Michigan X Google Scholar LinkedIn Enjoying the Dr.
- Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of the Dr.GPCR Podcast,. The catch? It’s all about understanding the system, not replacing it. From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲 Watch now: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Home → Flash News → Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery Published on May 22 GPCR Podcast Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery Previous Next Recent
- Can we preserve opioid pain relief without the side effects? 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid receptor could revolutionize treatment —with a 10x boost in methadone efficacy. Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship. 🎧 Full episode: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery Published on May 15 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery Previous Next Recent
- “Research is all about knowing when to walk and when to run.” –Ben Clements In Ep. 166 of the Dr.GPCR Podcast, hear how a postdoc is reshaping the conversation on opioid use, imposter syndrome, and the power of collaborative science. Why early-career voices are critical in GPCR drug discovery —and how lab culture makes all the difference. 🎧 Watch here: https://buff.ly/Kr3qKud #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
–Ben Clements In Ep. 166 of the Dr.GPCR Podcast, hear how a postdoc is reshaping the conversation on –Ben Clements In Ep. 166 of the Dr.GPCR Podcast, hear how a postdoc is reshaping the conversation on
- Dr. Benjamin Myers | Dr. GPCR Ecosystem
Benjamin Myers Ben Myers is an assistant professor at the University of Utah School of Medicine in Salt Ben’s research focuses on Smoothened and other class F GPCRs which play essential roles in embryonic More recently, Ben’s lab has begun studying GPCR signaling pathways that operate within the primary cilium Ben studied developmental and cancer signaling as a postdoctoral fellow with Philip Beachy at Stanford Prior to that, Ben received his Ph.D. from UCSF in 2008, where he worked with David Julius on the structure
- Check out the new optical BRET-based biosensor, Gαi bONE-GO! In neuronal cell lines, the use of Gαi bONE-GO revealed that several natural opioid neuropeptides act as partial agonists, contrary to their previous characterization as full agonists. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://buff.ly/e6gAlBv #gpcr#drgpcr | Dr. GPCR Ecosystem
Home → Flash News → Check out the new optical BRET-based biosensor, Gαi bONE-GO! In neuronal cell lines, the use of Gαi bONE-GO revealed that several natural opioid neuropeptides act Published on April 21, 2025 Category GPCR Weekly News Check out the new optical BRET-based biosensor, Gαi bONE-GO In neuronal cell lines, the use of Gαi bONE-GO revealed that several natural opioid neuropeptides act
- Dr. Maria Majellaro perfected her focaccia recipe. Then, with Celtarys, the team did the same for ligand-linker-fluorophore chemistry. It’s not just culinary precision, it’s a metaphor for drug discovery done right. In Ep. 168, she shares how Celtarys went from a thesis idea to a biotech reality. Meet Dr.GPCR’s new partner: Celtarys 🙌 👉 See what they’re cooking up now: Ep 168 with Dr. Maria Majellaro from Celtarys #GPCRresearchCommunity #DrGPCR #StartupScience #BiotechFounders #GPCRscientistNetwork | Dr. GPCR Ecosystem
It’s not just culinary precision, it’s a metaphor for drug discovery done right. #GPCRresearchCommunity #DrGPCR #StartupScience #BiotechFounders #GPCRscientistNetwork Published on June It’s not just culinary precision, it’s a metaphor for drug discovery done right.
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Because the TA-mediated mechanism is a “one and done” mechanism that is irreversible and prevents the Jose Rizo-Rey as a graduate student to elucidate the mechanisms of neurotransmitter release. Jones (Harvard Medical School); Jeffrey S.
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
’s research interests lies in the elucidation of signal transduction pathways in cancer, immune and bone The Rottapel lab has shown that 3BP2 has pleiotrophic function controlling bone homeostasis, immune cell
- insights into g protein coupling preference from cryo em structures of gq bound PTH1R | Dr. GPCR Ecosystem
Strategic implications for biased agonist design A critical advance for anyone working on class B1 GPCRs, bone
- irreversible drugs post 1 | Dr. GPCR Ecosystem
Unlike reversible ligands, their impact can persist long after the compound is gone — creating durable
- Dr. Graciela Pineyro | Dr. GPCR Ecosystem
She has done extensive work on the molecular pharmacology of opioid receptors and is currently focusing
- irreversible drugs post 2 | Dr. GPCR Ecosystem
on October 24, 2025 Category Terry's Corner Why do some inhibitors act long after the drug itself is gone
- Dr. Graciela Pineyro | Dr. GPCR Ecosystem
Graciela has done extensive work on the molecular pharmacology of opioid receptors, exploring their signaling
- Dr. Paul Insel | Dr. GPCR Ecosystem
physiology, receptor molecular pharmacology in cells, and animal models, and as he puts it has now he’s "gone
- Dr. Alix A. J. Rouault | Dr. GPCR Ecosystem
Cone’s lab was a clear choice for a postdoc. Dr. Cone was the first to clone the melanocortin receptors (the GPCRs that led to the discovery of MRAP2)
- Dr. Nariman Balenga | Dr. GPCR Ecosystem
parathyroid glands of patients with hyperparathyroidism and their impact on body calcium homeostasis and bone
- Courses by Terry | Dr. GPCR Ecosystem
Terry’s Corner $2,999 $ 2,999 Every year Only Founders Get Discounted Full Vault Access —Then It’s Gone
- About Dr. GPCR Podcast | Dr. GPCR Ecosystem
Anonymous I think it's really well done.
- Trainee Symposium II
awarded the Young Investigator Transdisciplinary Research Award (2022-2023 and 2023-2024) from the bone
- Re-cap of Endocrine Metabolic GPCR 2024 with the Organizers | Dr. GPCR Ecosystem
Her current research focuses on how metabolic GPCRs cross-talk and interact to regulate appetite and bone
- Pod-Be Our Guest | Dr. GPCR Ecosystem
Recordings are done on Zoom. Recordings are done on Zoom. Touch-up- my appearance. Adjust for low light.
- From Curiosity to Breakthrough: Ajay Yekkirala on GPCR Innovation | Dr. GPCR Ecosystem
entrepreneurial lessons no one tells postdocs: how to pitch, fail, and build a team Why asking “what if it can be done
- Dr. GPCR Summit 2021 | Dr. GPCR Ecosystem
Experience talks spanning time zones, with options for live or pre-recorded presentations. Get your All-Access ticket before they're gone by visiting Eventbrite today!
- Exploring Career Paths in GPCR Research with Dr. Jacek Mokrosiński | Dr. GPCR Ecosystem
They also highlighted the need for a work-life balance and the joy of a well-done job.
- Hacking GPCRs: Tools, Tech & Drug Discovery with Tom Sakmar & Ilana Kotliar | Dr. GPCR Ecosystem
A Long-Term Vision Realized “We've done this work for the past 30 years.” – Tom Sakmar Dr.
- Flash News: Your Hub for GPCR Insights and Scientific Conference Programs
24, 2025 Terry's Corner Read full article Why do some inhibitors act long after the drug itself is gone















