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Want to know what’s buzzing in the world of GPCRs?  under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zhou , Chungong Yu , Haicang Zhang , Dongbo Bu 🤩 Seriously, why would you want to miss out on all the awesomeness that comes with a DrGPCR Premium terminating CEO and other execs amid strategic review Trevena Reports Third Quarter 2024 Results and Provides Business

This reactive approach, driven by a "go fast" mindset, burns through precious capital and time, leaving This belief that we don't have time to build better systems is a costly miscalculation. We believe we don't have time to build better systems, but in reality, our most brilliant and expensive I’ve lived this firsthand, not just in theory, but by building these systems from the ground up. Our Chief Brainstorm Officer, Attila Foris , is building a system so transparent that anyone joining

Alex Serafini makes the case for building pain research from the clinic down, not the bench up. _____

At Alkermes , Sokhom Pin wasn’t just leading GPCR programs; he was building culture from the ground up The Challenge: Build a Team. Build a Lab. Build the R in R&D. He was tasked with building an in vitro pharmacology group from scratch , including infrastructure, hiring attitude and team fit , not just credentials He designed lab workflows that encouraged curiosity without burnout Sokhom knew this instinctively and built a system to support it.

Bursicon receptor gene HLGR2 as a potential RNA interference target for control of the fall webworm Hyphantria

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Dear GPCR Enthusiasts! Get ready to save the dates! Dr. GPCR University offers two live courses this fall that you won’t want to miss. Before the new semester kicks off, dive into our premium on-demand courses! With your membership, you’ll access over 500 minutes of top-notch content from Drs. Kenakin and Hoare on '   Applying Pharmacology to Drug Discovery ' and ' Advanced Data Analysis for GPCR Pharmacology .' Choose between our monthly or yearly plans (with a 5-day free trial) to enjoy these courses and snag 25% off early bird discounts on upcoming classes. Check out what’s coming in September and October: Sign up for both courses now and score a 25% early bird discount with a premium membership! Course Details: When:  Thursdays at 10 AM EST Format:  Engaging Online Lectures with access to pre-read materials. Perks Include: In-depth Reading Materials Access to a Private Community Certificate of Participation for each course Don’t miss out—grab this special offer today! s Check out the details of each course below: Open to the Public: Enrollment is Now Available! Hurry and secure your spot TODAY! Dates:  September 5 to 26, 2024 What You’ll Learn during the four sessions: How to measure pharmacologic activity of ligands (affinity, efficacy, co-operativity) Determining mechanisms of action for new GPCR ligands Key elements of a comprehensive and effective GPCR discovery strategy Exclusive 25% Early Bird Discount for Dr. GPCR Ecosysme Premium members. Secure your spot before public enrollment opens! Dates:  October 3 to 31, 2024 What You’ll Master during the five sessions: Utilizing new cellular assays to analyze GPCR ligand behavior Predicting activity and in vivo target coverage with real-time kinetics Discovering new ligands and unique GPCR behaviors for innovative drug profiles GPCR Event Highlight  11th Adhesion GPCR Workshop    Location : Mexico City Dates : October 23-25, 2024 Join us in the vibrant heart of Mexico City to connect with fellow scientists and delve into the latest advances in adhesion GPCR biology. Logo Contest : Let your creativity shine! Submit your design for our Logo Contest by August 15, 2024 (Yes, it's TODAY)! Sponsorship Opportunities : Elevate your brand’s visibility at this prestigious event. Contact us at Hello@DrGPCR.com to explore sponsorship options. Your participation is eagerly awaited! This week's highlight includes congrats to: Miles Thompson ,   Alexander Hauser ,   Caroline Gorvin ,   et al.   for their work on GPCR pharmacogenomics  Let’s dive into the   Classified GPCR News  from August 5th to 11th, 2024 GPCR Activation and Signaling Pharmacological characterization of the zebrafish Hrh2a histamine H2 receptor Revealing the graded activation mechanism of neurotensin receptor 1 Intracellular pathways of calcitonin gene-related peptide-induced relaxation of human coronary arteries: A key role for Gβγ subunit instead of cAMP Olanzapine manipulates neuroactive signals and may onset metabolic disturbances GPCR Binders, Drugs, and more Gut microbe-generated phenylacetylglutamine is an endogenous allosteric modulator of β2-adrenergic receptors GPCRs in Neuroscience In-silico predicted mouse melanopsins with blue spectral shifts deliver efficient subcellular signaling Striatal serotonin release signals reward value Ciliary length variations impact cilia-mediated signaling and biological responses The receptor tyrosine kinase IGF1R and its associated GPCRs are co-regulated by the noncoding RNA NEAT1 in Alzheimer's disease Nanoplastic at environmentally relevant concentrations induces toxicity across multiple generations associated with inhibition in germline G protein-coupled receptor CED-1 in Caenorhabditis elegans Calcium-sensing receptor regulates Kv7 channels via Gi/o protein signalling and modulates excitability of human induced pluripotent stem cell-derived nociceptive-like neurons Methods & Updates in GPCR Research G protein-coupled receptor (GPCR) pharmacogenomics Visualization of endogenous G proteins on endosomes and other organelles Reviews, GPCRs, and more Phytocannabinoids in neuromodulation: From omics to epigenetics The impact of nanobodies on GPCR structural biology and their potential as therapeutic agents Industry News Nxera Pharma Operational Highlights and Consolidated Results for the Second Quarter and First Half 2024 Cracking Codes in Cellular Communication Neurocrine Biosciences to Present at the Canaccord Genuity 44th Annual Growth Conference GPCR drugs make up a third of the market! GPCRs and mRNA antigens enable drug discovery and development Mapping GPCR-RAMP complexes with MolBoolean Screening GPR75 Modulators Using Medium-Throughput Reporter Gene Assay GPCR Therapeutics Optimizes the Joint Development of New Drugs Using Intralinks’ Virtual Data Room   GPCR Events, Meetings, and Webinars NEW September 5 - 6, 2024 | 4th Transatlantic ECI GPCR Symposium September 18, 2024 | FREE Webinar - The value of GPCR cell-based assays in drug discovery October 2024 | Biologics US 2024   October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral Shift for GPCRs October 23 - 25, 2024 | 11th Adhesion GPCR Workshop November 5 - 7, 2024 | 16th Annual PEGS Europe   July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research position Senior or Lead Researcher   Senior Scientist, Cryo-Electron Microscopy   Postdoctoral Research Associate Become a Premium Member! 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Switzerland Today, InterAx Biotech is pleased to announce that Carola Weiss has joined the company as VP Business Carola Weiss’ professional career brings deep expertise in business development, marketing & sales, licensing

Law, our newly named Chief Business Officer.

August 2022 "CHESTERBROOK, Pa., Aug. 11, 2022 (GLOBE NEWSWIRE) -- Trevena, Inc. (Nasdaq:TRVN), a biopharmaceutical company focused on the development and commercialization of novel medicines for patients with central nervous system (CNS) disorders, today reported its financial results for the second quarter ended June 30, 2022 and provided an overview of its recent operational highlights." Read more at the source #DrGPCR #GPCR #IndustryNews

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Burger , Arthur Christopoulos , David M. 🚨 Hurry to reserve your spot for the Principles of Pharmacology I & II BUNDLE before the Early

Irreversible binding isn’t a magic bullet. It’s a double-edged sword. Terry’s Corner and get: Frameworks proven in real discovery programs On-demand lessons  designed for busy That’s why discovery teams turn to Terry’s Corner: to build strategies that anticipate these collisions If you’re not designing with persistent enzyme interactions in mind, you’re building risk into your molecule

If you’re building tools or careers in GPCR science, this is your playbook. Eric Trinquet Built to Fail, Built to Win: Inside the IP1 Assay Origin Story The IP-One assay didn’t The pHSense Breakthrough: Two Dimensions of Discovery pHSense wasn’t built in a vacuum—it was born from From Theory to Tool: How Great Products Get Built pHSense didn’t materialize overnight. Build theories, but be ready to toss them.

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Built to Fail, Built to Win: The IP One Gamble After the success of their cAMP assay, Trinquet’s team The goal wasn’t to build a pH sensor—it was to create brighter, more stable lanthanide complexes for It’s when the tools you built in-house meet the problems no one saw coming. pHSense isn’t just a probe GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research or career. 👥 Build

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Breakthroughs this week: Lilly to build $5B manufacturing facility in Virginia; Novo Nordisk flags drug GPCR Podcast, the Revvity team built pHSense™ from the ground up by listening to what GPCR scientists

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