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Results found for "Ethan Dintzner"
- Paul Insel: Unbiased Discovery and the GPCRs We've Been Missing | Dr. GPCR Ecosystem
cellular environments Biased signaling in practice — Why the promise of biased agonism is more complicated than Biased signaling is real but harder to exploit than expected GPR68 couples to both Gq and Gs, and the A career redirected by a dinner and an empty schedule In 1975, Dr. Insel was the only unmarried scientist at a dinner with Al Gilman. During dinner with colleagues and Alfred Gillman , co-recipient of the 1994 Nobel Prize in Physiology
- Dr. Nariman Balenga | Dr. GPCR Ecosystem
At the height of curiosity, a seemingly naïve idea at the dinner table led to a side project by which
- Brian Arey: Discovering Signaling Bias at the FSH Receptor | Dr. GPCR Ecosystem
Drug discovery needs modulators more than it needs hammers Arey's philosophy of drug discovery is grounded He argues for a therapeutic strategy built around modulators that can be combined, rather than single argument that biased signaling is evolutionarily conserved, and why he chose a book over a review 48:09 Dinner "I'm not surprised." - Martin Rodbell, upon being shown Arey's FSH signaling data drawn on a dinner napkin
