Search Results

Discover how Celtarys Research is transforming GPCR assay development with fluorescent ligands in this probes for GPCR assays. GPCR, Celtarys will bring those lessons to the broader community, providing insight into assay development Whether you're designing assays, developing probes, or seeking better tools for GPCR drug discovery, , GPCR assay development , G protein-coupled receptors , GPCR podcast , Celtarys partnership Summary

Your One-Stop-Shop for GPCR Drug Discovery and Development Researchers developing GPCR-targeted therapeutics assay solutions for basic research through therapeutic discovery and development. Assay Principle of Eurofins DiscoverX Cell-based Assays Whether you are developing small-molecule or and development. platform spanning the entire discovery and development continuum.

assay, and his journey in GPCR product R&D. << Back to podcast list Strategic Partner(s) From Rare Earth Eric Trinquet What does it take to design a breakthrough GPCR assay—from idea to industrial impact? Eric Trinquet shares the inside story behind the development of pH Sense, Revvity’s latest innovation and product development, Eric takes us through the highs, failures, and scientific “aha” moments that field through hands-on assay development.

🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research We solve assay problems.” – Dr. /dr-gpcr-podcast/ep-168-with-dr. 🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research /dr-gpcr-podcast/ep-168-with-dr.

Michelle Halls reveals how organized GPCR signaling drives assay innovation and new therapeutic insights This conversation is especially valuable for scientists developing functional assays, fluorescence-based development and GPCR research. ⸻ Why It Might Hit Home If you’ve ever: Faced unexpected assay behavior Get behind-the-scenes conversations, advanced assay development strategies, and practical GPCR tools GPCR Premium .

Check out the development of a NanoBRET assay platform to detect intracellular ligands for the chemokine Check out the latest GPCR news in the Ecosystem today! Check out the development of a NanoBRET assay platform to detect intracellular ligands for the chemokine Check out the latest GPCR news in the Ecosystem today! ➡️ https://www.ecosystem.drgpcr.com/methods-and-updates-in-gpcr-research/development-of-a-nanobret-assay-platform-to-detect-intracellular-ligands-for-the-chemokine-receptors-ccr6

To address this, we developed the NTF release sensor (NRS), a genetically encoded reporter that facilitates in Drosophila, revealing NTF release and receptor dissociation within the developing nervous system. using a luciferase assay to detect NTF release events. In addition, the platform was used to develop assays for high-throughput screening for challenging adhesion research aims to leverage this knowledge to identify novel pharmacological targets and contribute to the development

View Reagents Explore Revvity’s GPCR Assay Technologies Tools designed to illuminate every step of GPCR He currently leads Revvity's Research and Development activities, focusing on biochemical and cellular Before joining Revvity, Eric worked for Cisbio Bioassays first as Director of Technological Development department, leading her team on the development of innovative HTRF™ and AlphaLISA™ kits for pharma, Eric Trinquet, Director of Research and Development at Revvity.

studies, and assay development in live cells and tissues. << Back to podcast list Strategic Partner( He explains what chemical design can solve that antibodies can’t, how to validate functional assay systems Balanced creativity in tool development with the pressure for reproducible, publication-grade data. Tried to build assays that behave in living cells—not just on paper. research group at the Leibniz Research Institute for Molecular Pharmacology (FMP) in Berlin, focusing on developing

✳️Celtarys is ready to support your assay development. Get to know more: Celtarys Research | Dr. GPCR Ecosystem | Dr. GPCR Podcast A casual postdoc in Santiago. A bold yes during the pandemic. Now? ✳️Celtarys is ready to support your assay development. Get to know more: Celtarys Research | Dr. GPCR Ecosystem | Dr.

His focus is on expanding commercial reach and accelerating the adoption of the company’s GPCR assay Her work focuses on organic synthesis, medicinal chemistry, and the development of GPCR-targeted tools tools to support real-time, non-radioactive GPCR assays. Custom Development Customized fluorescent ligands developed in less than 3 months with optimal properties GPCR Functional Assay Fluorescent GTPγS enables sensitive, non-radioactive GPCR activity assays for drug

GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds GPCR Podcast What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds

: The Evolution of GPCR Research Published on November 13, 2025 Category Dr. GPCR Podcast Back when GPCR assays were performed with single channel pipettes, failure wasn’t cheap. Michelle Halls still remembers pipetting one sample at a time, holding her breath to keep the assay alive GPCR Premium for deeper tools and insights: https://www.ecosystem.drgpcr.com/gpcr-university-pricing #GPCR #DrGPCR #DrugDiscovery #Pharmacology #Biotech Previous Next Recent Articles

David has over 20+ years of experience working in a drug discovery environment mainly in a specialist assay development role and most recently with Novartis. During this period David has made a significant contribution to the understanding of agonist/ antagonist GPCR His current interests include the development of HTS fluorescence-based kinetic binding assays specifically GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.

During my PhD, I learnt radioligand binding assays, behavioral assays, autoradiography, stereotaxic surgeries nervous system disorders realm to understand the neurobiology of neuropsychiatric disorders and to develop GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

Ilana Kotliar , his former graduate student, to explore the development of powerful multiplex tools designed Curiosity to Collaboration “We decided to evaluate the multiplexing methods... and found this Luminex assay ” – Tom Sakmar After exploring several screening techniques, the lab adopted the Luminex bead-based assay The team developed two main assets: A web interface to visualize antibody validations and GPCR-RAMP interactions Keyword Cloud GPCR-RAMP interactions , multiplex assays , GPCR research community , Dr.

GPCR to support assay development worldwide. leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast GPCR Podcast Started in medicinal chemistry. Got hooked on ligand design. Dr. GPCR to support assay development worldwide. leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast

How academia and biotech collaborate to scale GPCR tools—covering fluorescence assays, GPCR internalization when developing, validating, and distributing GPCR research tools. The episode explores gpcr internalization , fluorescence-based probe design, and how functional assay development benefits from scalable distribution rather than ad-hoc sharing. His research focuses on bottom-up chemical tool development for imaging and interrogating GPCRs and other

Accelerated Program Progression: Design robust assay cascades and establish key go/no-go points to speed assay platforms and in vitro models to deliver superior data quality and results. development to CRO selection or portfolio strategy, ensuring a tailored approach. 3 Collaborative Execution Accelerated Preclinical Progression I streamline critical operational processes, from advanced assay Small missteps can derail entire programs: underperforming assays, off-track CROs, and data that fails

GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025 Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to GPCR Courses 🚨 Exciting Opportunity for Professionals in Drug Development! GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025 Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to

By using signalling assays, radioligand binding assay, and microscopy, Gaidarov et al. suggested that Check out the latest GPCR news in the Ecosystem today! #drgpcr Published on May 19, 2025 Category GPCR Weekly News Did you know that certain ergot derivatives By using signalling assays, radioligand binding assay, and microscopy, Gaidarov et al. suggested that Check out the latest GPCR news in the Ecosystem today!

- Quantifying agonist pharmacology and biased agonism Class 3 - Antagonist pharmacology and binding assay the Optimization of Candidate Selection Lecture 1: The Eyes to See- The Importance of Pharmacologic Assays Aside from his vast experience in drug development, not to mention his extensive publication record, GPCR University? Dr. Summit A global gathering of researchers and professionals showcasing the latest developments in GPCR

Michelle Halls reveals how organized GPCR signaling drives assay innovation and new therapeutic insights Home → Flash News → How sensitive can a GPCR really be How sensitive can a GPCR really be? GPCR Podcast Think femtomolar. That’s the scale we’re talking about. This week on the Dr. /leadership-luck-and-gpcr-signaling 🎓 Explore Dr. GPCR Premium → https://www.ecosystem.drgpcr.com/gpcr-university #GPCR #DrGPCR #pharmacology #drugdiscovery

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Activation: Direct Communication of Extracellular Region with Transmembrane Domain in a Holo-Adhesion GPCR point mutant knock-in mouse, H381S Frank Kwarcinski Tethered Peptide Activation Mechanism of Adhesion GPCRs through assay development and high-throughput screening efforts. I have previous work experience at two separate contract research organizations centered on assay development

Home → Flash News → Exploring the combination of molecular simulation, pharmacological assays, and NMR Did you know that we work hard to bring you the most recent GPCR News, weekly? Published on December 10, 2024 Category GPCR Weekly News Exploring the combination of molecular simulation , pharmacological assays, and NMR to reveal the molecular mechanism of biased activation at the vasopressin Did you know that we work hard to bring you the most recent GPCR News, weekly?

Khorana’s lab made early key contributions and developed strategies to express, reconstitute and assay He also went on to discover a “counterion switch” in visual pigments and to develop strategies to assay Tom’s lab also developed an amber codon suppression method to genetically encode unnatural amino acids Early applications included “targeted photo-crosslinking,” and more recently, the parallel development GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

Brian Kobilka , studying the dimerization of GPCRs. Dr. His current work is mainly focused on screening and assay development to bridge the gap between in vitro and in vivo GPCR pharmacology. Juan José Fung on the web LinkedIn GPCR Therapeutics Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

She developed expertise over the past two decades studying structure/function relationships of GPCRs Her research centers on developing nanobody-ligand conjugates to target GPCRs, with a focus on receptors Driven by a passion for advancing drug development, John is committed to leveraging his expertise to research focuses on elucidating the molecular basis of membrane protein signalling using quantitative assays Further down the track, he aims to apply this knowledge to develop novel chemical treatments for neuronal

Flash News → pharmacology at your fingertips terrys corner launches Published on July 4, 2025 Category GPCR Weekly News Stronger pharmacology drives smarter decisions in GPCR discovery. Whether you’re refining assay strategy or evaluating data, these lessons give you the tools to think GPCR Weekly: ♦️ Yamina’s Corner—GPCR consulting to de-risk and accelerate your pipeline ♦️ Celtarys’ validated TR-FRET assay for CB1/CB2 ♦️ Chemokine-GPCR selectivity decoded ♦️ PTH1R structures reveal

assays. GPCR ecosystem to support researchers worldwide and expand access to high-performance tools for GPCR-targeted assays. GPCR ecosystem to support researchers worldwide and expand access to high-performance tools for GPCR-targeted are interpreted—and how those interpretations quietly shape SAR, lead selection, and development timelines