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  • Dr. GPCR Updates

    GPCR – Precision Tools for GPCR Assays Dr. GPCR and Celtarys Research have teamed up. features a discussion about a scalable GPCR-RAMP assay. Their global resource is now helping labs decode GPCR biology at scale. It’s exciting to see how the GPCR field is evolving. GPCR Team

  • Dr. GPCR and Eurofins DiscoverX Join Forces to Accelerate GPCR Drug Discovery

    GPCR , the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced GPCR . GPCR Dr. , expert-led courses, and networking. GPCR empowers scientists and organizations advancing GPCR biology and GPCR-targeted drug discovery.

  • Accelerating GPCR Drug Discovery

    But your GPCR program still isn't moving at the pace it should. The GPCR Data Dilemma: The Lego Bucket Problem I've seen promising GPCR programs generate massive volumes GPCR As the co-founder of Dr. GPCR, we've built a global hub connecting over 1,300 GPCR scientists dedicated to this field. Ready to Move Your GPCR Program Forward?

  • Ben Clements on Rescuing Opioids with GPCR Modulators

    The GPCR Angle Ben sees GPCRs as untapped goldmines for drug discovery. Ready to dive deeper into GPCR drug discovery? Want to push the boundaries of GPCR drug discovery? Start learning with our GPCR University today. _______________ Keyword Cloud: GPCR research community , GPCR drug discovery, mu-opioid receptor, positive allosteric modulators, GPCR training program, GPCR online course, GTPγS assay, chronic pain

  • Fluorescence Polarization in GPCR Research

    Target-based screening is now a fundamental pillar of drug development, and GPCRs are key targets for How Fluorescence Polarization Assays Work: Principles and Applications in GPCR Research FP assays work Optimizing GPCR Drug Discovery with Fluorescence Polarization: Key Advantages and Future Perspectives Compatible with various sources of GPCRs. Contact us  to drive further advancements in GPCR drug discovery!  

  • GPCR Collaboration: From Models to Medicine

    That perspective changed the moment he entered GPCR research . In his view, collaboration is not a bonus or an optional supplement—it is the only way GPCR drug discovery The cycle only works because every part is connected .   The GPCR Challenge What makes collaboration non-negotiable in GPCR research is the biology itself. GPCR Models Don’t Discover Drugs—People Do In GPCR research, the biggest breakthroughs won’t come from

  • Advantages of Fluorescent Probes in GPCR Assays

    GPCRs pose a critical challenge in drug discovery: a vast therapeutic potential with many targets yet However, over half of non-sensory GPCRs do not have drugs available in the clinic, opening the door to This means fluorescent probes enable a dynamic observation of GPCRs. common starting point for employing fluorescent probes in GPCR assays. Fluorescent ligands: Bringing light to emerging GPCR paradigms.

  • Integrated GPCR Drug Discovery: A Structured Framework for Modern Programs

    GPCR University Masterclass — Integrated GPCR Discovery in Practice Dr. New courses are delivered live, giving members the opportunity to ask questions directly to the instructors GPCR Masterclass ➤ Eurofins DiscoverX Partnership — Tools and Insight for GPCR Drug Discovery Modern GPCR Premium Membership Gives You an Edge GPCR drug discovery is accelerating — across obesity, CNS, GPCR operates as a membership-based, nonprofit initiative — built to strengthen the GPCR field through

  • From GPCR Data Chaos to Decisive Action

    Is Your GPCR Program Slowing Down—Even With Good Data? You’re not alone. GPCR Ecosystem. Strong science. Promising data. But no systems to turn it into momentum. GPCR, I’m connected to 1,300+ scientists and decision-makers worldwide. Who I Work With ✅ Biotech Teams  – Especially those lacking in-house GPCR leads or overwhelmed by CRO data chaos. ✅ Venture Capital Firms  – Looking to accelerate, troubleshoot, or validate GPCR assets

  • From Multiplex to Models: Scaling Up GPCR Discovery in the Post-Silo Era

    Watch Episode 167 Today’s GPCR scientists don’t want to study one interaction, they want to model the protein interactions  (e.g., 14-3-3) Heterodimerization Endogenous vs. overexpressed systems Orphan GPCR scientists are already expanding this work, bringing in computational layers  like AlphaFold to model GPCR-RAMP Listen to the complete episode to learn more. _________________ Keyword Cloud : GPCR scientist network , GPCR online course , GPCR data platform , multiplex assays , GPCR drug discovery

  • GPCR Happy Hour – Boston, Sept 2025

    That’s exactly why we created GPCR Happy Hour . GPCR’s nonprofit mission to unite and empower the GPCR community worldwide FOMO is real: if you’re not Be Part of the GPCR Community Dr. GPCR is a nonprofit global community  dedicated to building a strong, connected GPCR ecosystem. GPCR Happy Hour is more than a social event.

  • Understanding Enzyme Inhibition In GPCR Discovery Programs

    mutated GPCRs. , and concise reads on β-agonists, phospho-barcodes, and GPCR allostery. frameworks used in real discovery programs On-demand lessons built for busy scientists A voice in future course expert frameworks, and member-only discounts. 🔹 Who is it for? The pace of GPCR innovation is accelerating.

  • How Collaboration Drives GPCR Discoveries

    GPCR signaling wasn’t linear. It wasn’t clean. For years, the GPCR community wrestled with unreliable antibodies. Why GPCR Collaboration Is Essential for Modern Science Hodson makes the point bluntly: modern GPCR science It is the only path to meaningful discovery. And it’s not just about capability. Together, they push GPCR science faster.

  • The Truth About GPCR Product Launches: Years in the Making

    GPCR and Revvity. Watch Episode 174 Most scientists only see the final kit—the catalog number, the plate-ready reagents But there was a pivot: the tech had untapped potential for GPCRs. GPCR   Dr. GPCR X Revvity Collaboration ⸻ Want more like this? 👉 Join the Dr. GPCR Premium Ecosystem  for behind-the-scenes access to GPCR innovators, exclusive deep-dives, and practical

  • Terry’s Corner, Celtarys' Leap, and the $7B GPCR Horizon

    space focused on GPCR pharmacology. – GPCR mutations in cancer—drivers, passengers, or both?  GPCR Updates Learn Pharmacology That Drives Discovery  – From Dr. GPCR Podcast appearance. GPCR Team

  • Inside the New Dr. GPCR Ecosystem: Learning, Insight, and Momentum for 2026

    Here's how: Watch the course trailer ➤ Read the blog post ➤ Subscribe to the Kenakin Brief ➤ Dr. GPCR podcast , Dr. frameworks, GPCR University access, and member-only discounts. 🔹 Who is it for? With new courses, expanded programming, upcoming partnerships, and deeper community engagement ahead, GPCR Team

  • How System-Level GPCR Thinking Prevents Discovery Failures

    Upcoming events:  Adhesion GPCR Workshop; GRC—Transporters, Ion Channels & GPCRs; MPGPCR Joint Satellite GPCR Podcast: Chemical Probes for GPCR Imaging with Dr. But HCS only works when assays are built with rigor and powered by the right fluorescent ligands. GPCR Premium Membership Gives You an Edge Premium gives GPCR scientists and biotech teams a single, trusted and member-only discounts. 🔹 Who is it for?

  • Your GPCR Program Decisions Depend on Good Data Interpretation

    Welcome GPCR Fans,   In GPCR-targeted drug discovery, precision isn’t optional—it’s a requirement. GPCR Premium Members this week gain curated, early access to: Industry insights : GPCRs and mRNA in drug differences delays key milestones. 🗣️ “Thank you for bringing this (Principles of Pharmacology I) course Exclusive discounts on Terry’s Corner  digital pharmacology courses Priority access to insights from The complete Weekly News digest, jobs, upcoming events, classified industry intelligence, Courses, &

  • Allosteric Binding Demystified: Smarter GPCR Drug Discovery

    Hello GPCR Enthusiasts, Interpreting binding data isn’t optional—it’s career-defining. symposia across Europe, UK, and online—including neuroGPCR signaling deep-dives. Read the article now ➤ Discovery on Target - The Next Wave of GPCR Drug Discovery The 20th Annual GPCR-Based GPCR Premium Membership Gives You an Edge The GPCR field is advancing at breakneck speed. The pace of GPCR innovation is accelerating.

  • Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024

    Get your space suits on, GPCR cadets! Courses . Discounted GPCR courses - because who doesn't love a good deal?  From 2025, only Premium Members will have access to Classified GPCR News. Classified GPCR News  Let’s dive into the   Classified GPCR News from October 28th to November 3rd, 2024

  • GPCR Allosteric Modulation: Why Allostery is the Engine of Drug Discovery

    s latest lecture delivers high-impact insight crafted for teams navigating the complex behaviors of GPCR-targeting As Kenakin explains, all GPCR signaling is allosteric , and pretending otherwise introduces risk at every But without understanding how GPCR state changes  influence that affinity—or vice versa—drug discovery Unlock “GPCRs as Allosteric Machines” Now Only in Terry’s Corner Why Terry’s Corner Terry’s Pharmacology Corner  is your trusted, expert-led guide through the evolving landscape of GPCR science.

  • Targeting GPCRs in the CNS: Advances in Drug Discovery Strategies

    The central role of GPCRs in Neurological Disorders GPCRs are the largest family of membrane receptors Over 30% of FDA-approved drugs target GPCRs, with many targeting CNS located GPCRs. GPCR Structure, Activation, and Signaling Pathways in the Brain An understanding of GPCR structure is GPCR signaling: (A) an orthosteric ligand (orange) binds an inactive GPCR, the β2 adrenergic receptor Emerging GPCR Therapeutic Targets in CNS Drug Discovery GPCRs have been studied for decades, but there

  • Better GPCR Drug Discovery Decisions Start With Structured Learning

    You can now search courses by level, topic, or instructor. Legacy courses will migrate into this format over the coming weeks, with live courses returning in March In the meantime, Premium members continue to have full access to the legacy course pages. All courses remain included in Premium Membership. GPCR University courses — now included in Premium.

  • How GPCR Spatial Signaling Sparked a Scientific Journey

    Many GPCR scientists trace their origin story back to a single unexpected spark. Not a grand plan. Luck, Leadership & GPCR Signaling Michelle is clear: luck played a role. But so did choice. But luck only works if you say yes when the door opens. GPCR Podcast 🔓 Want to go deeper? Join   Dr. GPCR Premium  for exclusive tools, deep dives, and expert access.

  • Why Kinetics Matter More Than Kd in GPCR Drug Discovery

    Welcome GPCR Fans,   Every discovery-phase decision you make shapes your entire pipeline trajectory—and Must-read publications:  GPCRchimeraDB: Database of engineered GPCR designs. GPCR University Course Attendee Dr. Exclusive discounts on Terry’s Corner  digital pharmacology courses Priority access to insights from The pace of GPCR innovation is accelerating.

  • Assay Volume Control: Your GPCR Drug Discovery Power Lever

    Breakthroughs this week: C. elegans avoids EGCG via SRXA-7 GPCR; a bidirectional GPCR switch modulates allosteric site on an orphan GPCR. 🔍 This Week in Dr. of Discovery Shaped pHSense From HTRF to pHSense: The Long Game of GPCR Innovation Most scientists only GPCR innovation is accelerating. Access this week’s full Premium Edition here ➤ What our members say "Thank you for bringing this course

  • Enzyme Inhibition Pharmacology: The Hidden Gatekeepers of GPCR Drug Discovery

    Before your GPCR ligand ever meets its receptor, it meets the enzymes that determine whether it survives Discovery Program So what does that mean for discovery scientists designing the next generation of GPCR Even the most elegant GPCR ligand can fail if it never reaches its receptor. in real discovery programs On-demand lessons  designed for busy scientists Direct input  on future course Kenakin with your own enzyme or GPCR interaction puzzles.

  • How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs

    Eric Trinquet, a veteran innovator behind functional GPCR assays like HTRF and IP-One, believes rigid If you’re building tools or careers in GPCR science, this is your playbook. It began with an unmet need: how to track Gq-coupled GPCR activity without the mess of calcium flux or GPCR   Dr. GPCR X Revvity Collaboration ⸻ Want more like this? 👉 Join the Dr. GPCR Premium Ecosystem  for behind-the-scenes access to GPCR innovators, exclusive deep-dives, and practical

  • From Failed Experiments to Predictive GPCR Models

    Watch Episode 175 From failed assays to breakthroughs in GPCR modeling , Dr. At that point, very few GPCR crystal structures had been determined. Predictive GPCR-Ligand Modeling Carlsson's work quickly shifted from curiosity to impact. For Carlsson, this marked a shift in how his lab approached GPCR research. He came to see that effective GPCR research requires true interdisciplinary integration.

  • How Schild Analysis Protects Your Conclusions in GPCR Research

    Listen to the episode ➤ Quick Links Assess GPCR Biased Signaling of Agonist How GPCR Collaboration Built With live GPCR University courses returning next year and platform capabilities expanding, Premium pricing You also gain access to member-only discounts, full GPCR University content, and an integrated view of GPCR innovation is accelerating. GPCR Team

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