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GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs. GPCR Podcast 220 GPCRs. One platform. Endless questions. In Ep.167 of the Dr. GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs.

Home → Flash News → What if you could map GPCR-RAMP interactions across the entire superfamily in a single and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP GPCR Podcast What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP

Ilana Kotliar built a multiplexed platform to map GPCR-RAMP interactions and uncover autoantibody-driven The team developed two main assets: A web interface to visualize antibody validations and GPCR-RAMP interactions Beyond GPCR-RAMP: New Avenues “What if your favorite scaffold protein interacts with GPCRs?” – Tom Sakmar The constructs aren’t limited to RAMP interaction studies. Keyword Cloud GPCR-RAMP interactions , multiplex assays , GPCR research community , Dr.

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to : RAMP-interacting GPCR Pathways Date & Time Thursday, November 2nd / 4:30 PM Keynote Talk Abstract Coming GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Your One-Stop-Shop for GPCR Drug Discovery and Development Researchers developing GPCR-targeted therapeutics Browse products related to your obesity/diabetes target of interest: CALCRL and RAMP (AMs) GIPR GLP-1R GLP-2R GCGR GPR75 MC4R NPY2R (PYY) SSTR5 Activins CALCR and RAMPs (AMYs) Apelin (APJ/AGTRL1) Representative GPCR Podcast Oct 16, 2025 4 min read The Truth About GPCR Product Launches: Years in the Making What Contact a Eurofins DiscoverX Specialist or visit GPCR Product Solutions for more information on GPCR

Join the GPCR Retreat: Exploring the Frontiers of GPCR Biology! Embrace diversity in a limited-capacity event fostering mentor-trainee interactions. The fall colors of the leaves are spectacular, and the weekend of science is an intense and interactive unquestionably one of the pioneers involved in deciphering how receptor activity-modifying proteins or RAMPs We are thrilled by the overwhelming interest in this event by the GPCR research community.

Her work is primarily focused on class B GPCRs and their interactions with RAMPs. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

Ilana uses chemical biology-based methods to study the regulation and protein-protein interactions of GPCRs and a small family of accessory proteins called RAMPs. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

He introduced molecular pharmacology to a wide range of the company's GPCR projects and was able to initiate These included the identification of RAMPs (solving some CGRP family issues) and the GABA B, carboxylic GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

Home Registration Full Agenda Venue Travel Tips Sponsors Special Issue on Adhesion GPCRs CINVESTAV, Mexico City, Mexico October 23-25 Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation Tobias Langenhan The Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl Dimitris map of thermogenic fat Gavin Zhang NovoiSMART - A new platform for GPCR antibody drug discovery

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program GPCR Community Presentation Breaking Barriers: My Journey from Mexico to the Heart of the Dr. GPCR Ecosystem and beyond About Monserrat Avila Zozaya "My doctoral research was focused on investigating My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program This made me pursue my higher education in the field of adhesion GPCRs. Emmanouil Kyrloglou on the web Adhesion GPCR Consortium LinkedIn A single cell GPCR map of thermogenic , located within the GPCR autoproteolysis inducing (GAIN) domain. receptors, which exhibit large multi-domain extracellular N-termini that mediate cell-cell and cell-matrix interactions

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Mihaylov Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl I have recently also developed a strong interest in adhesion GPCRs and in particular, Bai1. " Simeon Mihaylov on the web Crick LinkedIn X (Twitter) Google Scholar Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl Anne Bormann Abstract Only available for AGPCR 24 Attendees Authors

Discover the essence of GPCR Retreat, an international GPCR Event that empowers the GPCR field. Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat The GPCR Retreat focuses on advances in our understanding of how GPCRs operate in cell communication. One of the core values of this international meeting is to promote interactions among all participants in the Ottawa 2017 edition, to showcase the breadth of diversity in GPCR trainee communities.

Subscribe to the Adhesion GPCR Workshop 2024 newsletter. Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register AGPCR Newsletter Adhesion GPCR Consortium Newsletter - May 2024 Welcome to the 4th official Adhesion GPCR Consortium newsletter GPCR News Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program signaling pathway of the ADGRA homolog Remoulade in Drosophila Beatriz Blanco Redondo The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation Willem Berend Post Uncovering The mammalian Remo homolog ADGRA2/Gpr124 cooperates with other GPCRs of the Frizzled family, and the Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation Willem Berend Post Abstract

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program Download : RAMP-interacting GPCR Pathways Inaugural Marc G. Caron Keynote Lecture Kathleen M. of Madrid Read More Friday, November 3rd / 12:10 PM Lunch 1 Read More Friday, November 3rd / 1:30 PM Interaction du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program function The NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner bioSens-All: A Multiparametric BRET-Based Platform for Comprehensive Profiling of adhesion GPCR Signaling Stephanie Häfner Abstract "G Protein-coupled receptors (GPCRs) are common drug targets, yet no approved ), with a particular focus on the adhesion GPCRs (aGPCRs) family.

Home → Flash News → encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network Published on July 7, 2025 Category GPCR Weekly News How do chemokines and GPCRs decode selectivity Cell paper delivers the answer—mapping how conserved and variable sequence–structure elements govern interaction logic across 46 chemokines and 23 GPCRs. unstructured regions ♦️ Includes a web tool + viral chemokine engineering demo This is a must-read for GPCR

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program a key regulator of lymphatic endothelial cell identity and function Monserrat Avila Zozaya Adhesion GPCR My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, increase radiosensitivity Like many other aGPCRs, ADGRG6 undergoes autoproteolysis at the GPCR-autoproteolysis site (GPS) enclosed

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Activation: Direct Communication of Extracellular Region with Transmembrane Domain in a Holo-Adhesion GPCR point mutant knock-in mouse, H381S Frank Kwarcinski Tethered Peptide Activation Mechanism of Adhesion GPCRs In this ECR-mediated mechanism of activation, the ECR-7TM communication is altered by transient interactions Frank Kwarcinski on the web LinkedIn Tethered Peptide Activation Mechanism of Adhesion GPCRs Peng Xiao

Dr GPCR is a 501(c)(3) non-profit. global GPCR community better — by upgrading the Dr GPCR University, creating more learning opportunities to make cutting-edge GPCR knowledge accessible to everyone Dr GPCR Retreat: offering free or affordable around the world - $250+ 👉 Expands Dr GPCR University with new lessons, updated materials, and interactive Now to Support the Dr GPCR Ecosystem

GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors GPCR podcast. Dr. My long-term interest is focused on understanding the mechanisms mediated by GPCRs at the cellular communication University, with a deep interest in understanding drug-receptor interactions. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Adhesion GPCR Researcher associate, Netherlands Brain Bank" Cheng-Chih Hsiao on the web LinkedIn ReseachGate Adhesion GPCR Attendees About Douglas Tilley "Research in the Tilley laboratory focuses primarily upon aspects of GPCR function in the heart in an effort to uncover novel therapeutic directions for HF, including adhesion GPCRs

GPCR University? Dr. G protein-coupled receptors (GPCRs). Virtual Café Listen to casual, interactive discussions with experts in the field. GPCR University Masterclasses? in GPCR research is welcome to join.

WNT-MB is driven by mutations of the CTNNB1 gene, activating ß-catenin-dependent signaling; however, no interactions MAGI3, a PDZ-containing scaffolding protein is known to downregulate WNT signaling by interacting with between BAI3 and ß-catenin signaling through MAGI3 in WNT-MB, we probed for potential protein-protein interactions We found an interaction between BAI3 and MAGI3 in mouse brain lysates. The y-maze showed a significant sex by genotype interactions with GPR110 KO male mice having increased

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Langenhan Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong Kim The Adhesion GPCR GPR110 Deletion Hee-Yong Kim Abstract "G-protein coupled receptor 110 (ADGRF1, GPR110), an adhesion GPCR In this study, we report the discovery of an adhesion GPCR, named Cupidon, that regulates the switch I have a particular interest in understanding the premetazoan function of adhesion GPCRs."

My long-term research interests involve resolving signaling pathways downstream of aGPCRs and establishing a basis for understanding aGPCR biology in the nervous system. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Better Questions in Science: A Practical Guide for Emerging Researchers When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

His research focuses on novel paradigms of drug action at GPCRs, particularly allosteric modulation and Allosteric Modulation and Drug Discovery Yamina and Arthur delved into the complexities of protein-protein interactions They discussed various modulatory elements, such as RAMPs, G proteins, and GRKs, with Arthur recounting his initial collaboration with Patrick Sexton on RAMPs and amylin receptors. GPCR Podcast? Leave a Review.

GPCR unites researchers, industry, and partners to accelerate GPCR science and drug discovery—through GPCR Ecosystem We unite the GPCR community to advance drug discovery. We bring the GPCR community together to fuel GPCR drug discovery—one receptor at a time. across the global GPCR ecosystem. Partner perks: Direct interaction with researchers, founders, and decision‑makers Access to all member