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- 220 GPCRs. One platform. Endless questions. In Ep.167 of the Dr. GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex, dual-tagged constructs, and open science. Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCR #GPCRpodcast #GPCRtools #OpenScience | Dr. GPCR Ecosystem
GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs. GPCR Podcast 220 GPCRs. One platform. Endless questions. In Ep.167 of the Dr. GPCR Podcast, Tom Sakmar and Ilana Kotliar reveal a full GPCR-RAMP interaction map—powered by Luminex Big win for the GPCR community. ✳️ Listen now: Ep 167 with Drs.
- What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment? That’s precisely what Dr. Kotliar from the Sakmar lab made possible! In Ep.167 of the Dr. GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research community. ✳️ Listen to the episode: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast | Dr. GPCR Ecosystem
Home → Flash News → What if you could map GPCR-RAMP interactions across the entire superfamily in a single and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP GPCR Podcast What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP
- Hacking GPCRs: Tools, Tech & Drug Discovery with Tom Sakmar & Ilana Kotliar | Dr. GPCR Ecosystem
Ilana Kotliar built a multiplexed platform to map GPCR-RAMP interactions and uncover autoantibody-driven The team developed two main assets: A web interface to visualize antibody validations and GPCR-RAMP interactions Beyond GPCR-RAMP: New Avenues “What if your favorite scaffold protein interacts with GPCRs?” – Tom Sakmar The constructs aren’t limited to RAMP interaction studies. Keyword Cloud GPCR-RAMP interactions , multiplex assays , GPCR research community , Dr.
- "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to : RAMP-interacting GPCR Pathways Date & Time Thursday, November 2nd / 4:30 PM Keynote Talk Abstract Coming GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Dr. Debbie Hay | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Dr. Debbie Hay About this episode Dr. Her work is primarily focused on class B GPCRs and their interactions with RAMPs. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening to this podcast episode
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
Join the GPCR Retreat: Exploring the Frontiers of GPCR Biology! Embrace diversity in a limited-capacity event fostering mentor-trainee interactions. The fall colors of the leaves are spectacular, and the weekend of science is an intense and interactive unquestionably one of the pioneers involved in deciphering how receptor activity-modifying proteins or RAMPs We are thrilled by the overwhelming interest in this event by the GPCR research community.
- Dr. Ilana Kotliar | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Dr. Ilana Kotliar About Dr. Ilana uses chemical biology-based methods to study the regulation and protein-protein interactions of GPCRs and a small family of accessory proteins called RAMPs. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research
- Dr. Steven Foord | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Dr. Steven Foord About Dr. These included the identification of RAMPs (solving some CGRP family issues) and the GABA B, carboxylic GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening to this podcast episode
- Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program GPCR Community Presentation Breaking Barriers: My Journey from Mexico to the Heart of the Dr. GPCR Ecosystem and beyond About Monserrat Avila Zozaya "My doctoral research was focused on investigating My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR < Previous Session Next Session >
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program This made me pursue my higher education in the field of adhesion GPCRs. Emmanouil Kyrloglou on the web Adhesion GPCR Consortium LinkedIn A single cell GPCR map of thermogenic , located within the GPCR autoproteolysis inducing (GAIN) domain. receptors, which exhibit large multi-domain extracellular N-termini that mediate cell-cell and cell-matrix interactions
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Mihaylov Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl I have recently also developed a strong interest in adhesion GPCRs and in particular, Bai1. " Simeon Mihaylov on the web Crick LinkedIn X (Twitter) Google Scholar Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl Anne Bormann Abstract Only available for AGPCR 24 Attendees Authors
- GPCR Retreat | Dr. GPCR Ecosystem
Discover the essence of GPCR Retreat, an international GPCR Event that empowers the GPCR field. Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat The GPCR Retreat focuses on advances in our understanding of how GPCRs operate in cell communication. One of the core values of this international meeting is to promote interactions among all participants in the Ottawa 2017 edition, to showcase the breadth of diversity in GPCR trainee communities.
- Newsletter for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Subscribe to the Adhesion GPCR Workshop 2024 newsletter. Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register AGPCR Newsletter Adhesion GPCR Consortium Newsletter - May 2024 Welcome to the 4th official Adhesion GPCR Consortium newsletter GPCR News Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program.
- Session VII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program signaling pathway of the ADGRA homolog Remoulade in Drosophila Beatriz Blanco Redondo The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation Willem Berend Post Uncovering The mammalian Remo homolog ADGRA2/Gpr124 cooperates with other GPCRs of the Frizzled family, and the Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation Willem Berend Post Abstract
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program function The NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner bioSens-All: A Multiparametric BRET-Based Platform for Comprehensive Profiling of adhesion GPCR Signaling Stephanie Häfner Abstract "G Protein-coupled receptors (GPCRs) are common drug targets, yet no approved ), with a particular focus on the adhesion GPCRs (aGPCRs) family.
- encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network | Dr. GPCR Ecosystem
Home → Flash News → encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network Published on July 7, 2025 Category GPCR Weekly News How do chemokines and GPCRs decode selectivity Cell paper delivers the answer—mapping how conserved and variable sequence–structure elements govern interaction logic across 46 chemokines and 23 GPCRs. unstructured regions ♦️ Includes a web tool + viral chemokine engineering demo This is a must-read for GPCR
- Nicole Perry-Hauser | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I am a postdoctoral My long-term research interests involve resolving signaling pathways downstream of aGPCRs and establishing GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening to this podcast episode
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program a key regulator of lymphatic endothelial cell identity and function Monserrat Avila Zozaya Adhesion GPCR My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, increase radiosensitivity Like many other aGPCRs, ADGRG6 undergoes autoproteolysis at the GPCR-autoproteolysis site (GPS) enclosed
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Activation: Direct Communication of Extracellular Region with Transmembrane Domain in a Holo-Adhesion GPCR point mutant knock-in mouse, H381S Frank Kwarcinski Tethered Peptide Activation Mechanism of Adhesion GPCRs In this ECR-mediated mechanism of activation, the ECR-7TM communication is altered by transient interactions Frank Kwarcinski on the web LinkedIn Tethered Peptide Activation Mechanism of Adhesion GPCRs Peng Xiao
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- Dr. GPCR Team | Dr. GPCR Ecosystem
GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors GPCR podcast. Dr. My long-term interest is focused on understanding the mechanisms mediated by GPCRs at the cellular communication University, with a deep interest in understanding drug-receptor interactions. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.
- A Brief History of allosteric modulation with Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners A Brief History of allosteric modulation with Dr. Allosteric Modulation and Drug Discovery Yamina and Arthur delved into the complexities of protein-protein interactions They discussed various modulatory elements, such as RAMPs, G proteins, and GRKs, with Arthur recounting his initial collaboration with Patrick Sexton on RAMPs and amylin receptors. GPCR Podcast? Leave a Review.
- Session VIII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Adhesion GPCR Researcher associate, Netherlands Brain Bank" Cheng-Chih Hsiao on the web LinkedIn ReseachGate Adhesion GPCR Attendees About Douglas Tilley "Research in the Tilley laboratory focuses primarily upon aspects of GPCR function in the heart in an effort to uncover novel therapeutic directions for HF, including adhesion GPCRs
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
WNT-MB is driven by mutations of the CTNNB1 gene, activating ß-catenin-dependent signaling; however, no interactions MAGI3, a PDZ-containing scaffolding protein is known to downregulate WNT signaling by interacting with between BAI3 and ß-catenin signaling through MAGI3 in WNT-MB, we probed for potential protein-protein interactions We found an interaction between BAI3 and MAGI3 in mouse brain lysates. The y-maze showed a significant sex by genotype interactions with GPR110 KO male mice having increased
- Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Langenhan Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong Kim The Adhesion GPCR GPR110 Deletion Hee-Yong Kim Abstract "G-protein coupled receptor 110 (ADGRF1, GPR110), an adhesion GPCR In this study, we report the discovery of an adhesion GPCR, named Cupidon, that regulates the switch I have a particular interest in understanding the premetazoan function of adhesion GPCRs."
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- About Dr. GPCR Ecosystem | Uniting the GPCR Community to Advance Drug Discovery
GPCR unites researchers, industry, and partners to accelerate GPCR science and drug discovery—through GPCR Ecosystem We unite the GPCR community to advance drug discovery. We bring the GPCR community together to fuel GPCR drug discovery—one receptor at a time. across the global GPCR ecosystem. Partner perks: Direct interaction with researchers, founders, and decision‑makers Access to all member
- Foundry for GPCR Organizations | Dr. GPCR Ecosystem
GPCR Foundry: Accelerate GPCR Drug Discovery Move from idea to insight—faster, smarter, and with confidence GPCR Foundry? GPCR Foundry? The Dr. GPCR Foundry is a nonprofit platform designed to help biotech leaders accelerate GPCR drug discovery GPCR Foundry?
- GPCR Weekly News | Dr. GPCR Ecosystem
Your go-to hub for everything GPCR! GPCR Weekly News - Your Hub for GPCR Research, Industry Updates, Jobs & Events Delivered straight to Whether you're a GPCR scientist, biotech innovator, or industry professional, GPCR Weekly News keeps Week in GPCRs Read Full Issue November 14 - 20, 2025 Crafting Chemical Keys for GPCR Drug Discovery GPCR initiative.
- Sponsorship Prospectus for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Explore sponsorship opportunities for the Adhesion GPCR Workshop 2024. SPONSORSHIP PROSPECTUS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Sponsor We are delighted to present the sponsorship opportunities available for Adhesion GPCR Workshop 2024, About the Adhesion GPCR Workshop 2024: Adhesion GPCR Workshop 2024 is a high-profile expert conference GPCR workshop 2024 and its preliminary program.









