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Results found for "GPR6"
- Dr. Hannes Schihada | Dr. GPCR Ecosystem
Curie PostDoc Fellowship in order to investigate and find better ligands for the orphan class A GPCRs , GPR3 , GPR6 , and GPR12 .
- Brian Arey - Part 2: GPCR Drug Discovery and the Science Nobody Publishes | Dr. GPCR Ecosystem
Brian Arey on GPCR drug discovery from the inside - GPR56 mechanotransduction, the KLF2 pathway, organizational discovery: from pathophysiology to program governance GPCR mechanotransduction in endothelial cells: GPR56 GPR56 as a GPCR mechanosensor in endothelial cells - a decade ahead of the published literature Working on endothelial cell responses to shear stress, Arey identified GPR56 as a candidate mechanosensor before -56, showing that GPR-56 was a mechanotransducer in endothelial cells.
- Signals, pH, and Discovery : Cracking GPCR Mysteries with Dr. Ian Chronis | Dr. GPCR Ecosystem
Discover how GPR65 reshapes our understanding of GPCR signaling and its role in cancer, with Dr. His research centers on the beta-2 adrenergic receptor and GPR65 , a proton-sensing receptor with promising He shares fascinating findings from his work on GPR65 , highlighting its unusual constitutive internalization Yamina underscores the therapeutic potential of GPR65, especially in the context of cancer immunotherapy
- Paul Insel: Unbiased Discovery and the GPCRs We've Been Missing | Dr. GPCR Ecosystem
In pancreatic cancer, proton-sensing GPCRs such as GPR68 are dramatically upregulated in cancer-associated Proton-sensing GPCRs create a feedback loop in pancreatic cancer GPR68 is dramatically upregulated in The tumor signals fibroblasts to raise GPR68 expression, and the low pH of the tumor microenvironment Biased signaling is real but harder to exploit than expected GPR68 couples to both Gq and Gs, and the purinergic to proton-sensing GPCRs 13:19 Proton-sensing GPCRs: what they are and why they matter 16:18 GPR68
- Dr. Nariman Balenga | Dr. GPCR Ecosystem
I studied the function of RGS5, calcium-sensing receptor, and an orphan adhesion GPCR, GPR64/ADGRG2 in
- Dr. Randy Hall | Dr. GPCR Ecosystem
actions of the neuroprotective receptors GPR37 & GPR37L1 as well as the adhesion GPCRs BAI1, BAI2, and GPR56
- Dr. Michael Feigin | Dr. GPCR Ecosystem
The team found that these drugs could interact with GPR68, which is highly expressed in cancer-associated Modulation Yamina and Mike had a discussion about their research on GPCRs, specifically focusing on GPR68
- Dr. Gregory Tall | Dr. GPCR Ecosystem
may happen for the 33 adhesion GPCRs in complex physiological contexts…one being our discovery that GPR56
- Jennifer Pluznick: Olfactory Receptors in the Kidney and the Gut-Microbe Signal | Dr. GPCR Ecosystem
Her lab studies the role of understudied GPCRs — olfactory receptors, taste receptors, and orphan GPRs
