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Results found for "Jana Selent"
- Illuminating Functional Selectivity and Allosterism at GPCRs.
Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Illuminating Functional Selectivity
- Distinct sub-cellular signal propagation as a component of functional selectivity
Retreat Program < Back to schedule Distinct sub-cellular signal propagation as a component of functional selectivity
- Structure-based discovery of functionally selective 5-HT1A receptor agonists
Committee Sponsors GPCR Retreat Program < Back to schedule Structure-based discovery of functionally selective Peter Gmeiner has been spokesman of the Research Training Group "Medicinal Chemistry of Selective GPCR
- encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network | Dr. GPCR Ecosystem
Home → Flash News → encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network Published on July 7, 2025 Category GPCR Weekly News How do chemokines and GPCRs decode selectivity
- Did you know allosteric modulators can change the GPCR G protein subtype selectivity? Have a look at this study to dive deep into its molecular mechanism. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox. | Dr. GPCR Ecosystem
Home → Flash News → Did you know allosteric modulators can change the GPCR G protein subtype selectivity Category GPCR Weekly News Did you know allosteric modulators can change the GPCR G protein subtype selectivity www.ecosystem.drgpcr.com/gpcr-binders-drugs-and-more/design-of-allosteric-modulators-that-change-gpcr-g-protein-subtype-selectivity
- In case you haven’t heard, Dr. Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery programs that extend the discovery process and increase therapeutic opportunity. | Dr. GPCR Ecosystem
start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection https://www.ecosystem.drgpcr.com/advanced-methods-for-the-optimization-of-candidate-selection #gpcr #
- ⚠️ Registration Deadline today! This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection with Dr. Terry Kenakin. Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. | Dr. GPCR Ecosystem
to register for Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection to register for Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection https://www.ecosystem.drgpcr.com/advanced-methods-for-the-optimization-of-candidate-selection #gpcr #
- Did you know? 🌟 Researchers have developed reversibly photoswitchable allosteric modulators for Class A GPCRs! 🧬💡 These innovative compounds, “Photo-BQCisA” and “Photo-BQCtrAns,” offer subtype-selective precision by combining allosteric modulation with light control, paving the way for new therapeutic strategies targeting muscarinic receptors (M1-M5). 🔬✨ Learn more about this breakthrough in the Ecosystem! | Dr. GPCR Ecosystem
🧬💡 These innovative compounds, “Photo-BQCisA” and “Photo-BQCtrAns,” offer subtype-selective precision “Photo-BQCtrAns,” offer subtype-selective precision by combining allosteric modulation with light control
- This new study reveals how the conformation of parathyroid hormone (PTH) and the C-terminal helix α5 of Gα regulate the selective coupling of PTH1R to Gs or Gq. Through Cryo-EM and single-cell experiments, the authors show differences in binding affinity, duration, and strength. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
reveals how the conformation of parathyroid hormone (PTH) and the C-terminal helix α5 of Gα regulate the selective reveals how the conformation of parathyroid hormone (PTH) and the C-terminal helix α5 of Gα regulate the selective
- Unlock your pharmacology potential with Terry’s Corner. No fluff. Just clear, on-demand insight from Dr. Terry Kenakin—built for scientists at every level. 🟢 Building core expertise? Learn dose-response, agonism, binding, bias, kinetics, and the models that build real confidence. 🟢 Driving drug discovery? Apply pharmacology to selectivity, ADME, early safety, and smarter decision-making. 🟢 Already a drug hunter? Sharpen your edge with allosteric modulation, residence time, molecular dynamics, and translational PK/PD. Learn on-demand. Apply immediately. Early access begins July 1 → https://www.terrykenakin.com #pharmacology #GPCRscience #drugdiscovery #TerrysCorner #biotechtraining | Dr. GPCR Ecosystem
Apply pharmacology to selectivity, ADME, early safety, and smarter decision-making. 🟢 Already a drug Apply pharmacology to selectivity, ADME, early safety, and smarter decision-making. 🟢 Already a drug
- Dr. Robert F. Bruns | Dr. GPCR Ecosystem
He taught himself chemoinformatics as a way to optimize compound selection for screening, and in 1997 He supported the D1 PAM project in various roles from its inception in 2002 until selection of a clinical
- Dr. GPCR University Vault | Dr. GPCR Ecosystem
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- Terry's Corner is Officially LIVE! 🎉 This is your new go-to for mastering drug discovery pharmacology. No fluff, just clear, on-demand insights from Terry Kenakin. Building core expertise? Master dose-response, binding, kinetics, and foundational models. Driving drug discovery? Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter? Sharpen your edge with allosteric bias, residence time, and translational PK/PD. Learn on-demand, apply immediately: https://terrykenakin.com #DrGPCR #GPCR #pharmacology #TerrysCorner #DrugDiscovery | Dr. GPCR Ecosystem
Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter? Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter?
- Dr. Lauren M. Slosky | Dr. GPCR Ecosystem
linking distinct signaling pathways with their physiological effects and may serve as the basis for more selective the Slosky Lab is now working to understand how the principles of receptor allosterism and functional selectivity
- Yao Lu (Jackie) | Dr. GPCR Ecosystem
) "Jackie is a Ph.D. student, at Monash University, Australia, investigating the role of functional selectivity
- master gpcr pharmacologic models before its too late | Dr. GPCR Ecosystem
Yamina’s Corner exposes the silent drift killing GPCR programs (and how to reverse it).
- Irfan Dhanidina, Dr. Kathleen Caron and Dr. Lauren Slosky | Dr. GPCR Ecosystem
role at Orion Biotechnology, I work at the intersection of science and business, which includes target selection linking distinct signaling pathways with their physiological effects and may serve as the basis for more selective the Slosky Lab is now working to understand how the principles of receptor allosterism and functional selectivity
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
Additionally, each symposium of the GPCR Retreat 2023 will include one trainee short talk selected from encouraged to register to the meeting and submit an abstract for consideration for the trainee symposia and selected
- irreversible drugs post 1 | Dr. GPCR Ecosystem
In modern discovery programs, that’s a decisive advantage (or a hidden liability) in candidate selection
- pharmacology at your fingertips terrys corner launches | Dr. GPCR Ecosystem
de-risk and accelerate your pipeline ♦️ Celtarys’ validated TR-FRET assay for CB1/CB2 ♦️ Chemokine-GPCR selectivity
- Logo Contest for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
deadline will not be considered) Designs or inquiries should be sent to this email The prize for the selected
- Yamina's Corner | Dr. GPCR Ecosystem
Insights: Translate complex GPCR pharmacology into clear decisions for lead optimization and candidate selection Together, we clarify specific, measurable goals, from target validation and assay development to CRO selection Whether it's optimizing CRO selection, building robust internal capabilities, or translating complex
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and
- Dr. Graeme Milligan | Dr. GPCR Ecosystem
His experience also includes translating knowledge generated into the selection of targets, screening
- Dylan Eiger | Dr. GPCR Ecosystem
phosphorylation (phosphorylation barcodes) and subcellular GPCR signaling in directing functionally selective
- Dr. GPCR | Explore the Ecosystem for GPCR Professionals and Enthusiasts
Valid until canceled Select 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research, careers
- Dr. Khaled Abdelrahman | Dr. GPCR Ecosystem
He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and
- GPCR Retreat Registration 2023 | Dr. GPCR Ecosystem
to register for the meeting and submit an abstract for consideration for the trainee symposium and selected
- Courses by Terry | Dr. GPCR Ecosystem
Valid until canceled 7 day free trial Select Watch 4 New Courses Each Month Connect in a Private Drug












