Matt Barnes appointed President of Heptares Therapeutics Ltd., and Head of UK R&D Tokyo, Japan and Cambridge

Burning Cash Isn’t the Problem. Burning Alignment Is. You track the burn rate. You watch the runway shrink. You delay hires. That’s what we call the hidden burn . 👉 This post breaks down how biotech misalignment happens, what And by the time you catch it, your burn rate is up and your traction is down. They have strong early data and an even stronger burn rate. Everyone’s busy. No one’s clear.

They track burn rate, but not decision reversibility. The real warning signs are not financial numbers. they can clearly explain their burn rate. The problem is that burn rate measures spending, not freedom. The math checks out.

Explore how GPCR signaling shapes mosquito feeding and mating behaviors with Dr. Laura Duvall. Back to podcast list Strategic Partner(s) Why Mosquitoes Hunt You: GPCR Control of Blood Feeding and Mating in Drosophila to mosquito behavior, and lays out why a receptor built to regulate host seeking and mating and suppresses her receptivity to mate again, sometimes for the rest of her life. Disrupting it experimentally can leave females able to mate with multiple males.

rescued a CRF drug discovery program, and why a career in GPCR data analysis starts with asking what the math Which ligand binds tightest, ranks highest, earns the most attention in an SAR campaign. For Hoare, the unsolved problem isn't the biology — it's the math no one wrote down. The barrier is not the math itself but the habit of reaching for it. 4. pharmacology data analyst and GPCR consultant 03:19 Origin story — the ATP calculation that first connected math

John shared his experiences in high school, where he developed a keen interest in advanced physics and math He participated in various academic competitions, including math, physics, and chemistry contests.