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Posts (16)
- Dr. Tim De Groof - Dr. GPCR Podcast
It’s not often when you get the best of both worlds - nano-bodies and #GPCRs.
- Decoding β-Arrestins: from Structure to function
signaling occurs within a 100 nm range from the point of origin, suggesting the formation of active "nano
- Illuminating C5aR Biology: The Role of Fluorescent Ligands in GPCR Research
activity was observed in the Calcium Flux Assay for the functionalized ligands based on P1 (low nanomolar
Other Pages (4)
- Steve McCloskey | Dr. GPCR Ecosystem
After graduating from UCSD he founded Nanome Inc to build Virtual Reality solutions for Scientists and
- David Gloriam: Orphan Receptors, GPCRDB, and the Data Revolution in GPCR Pharmacology | Dr. GPCR Ecosystem
group contributed to the de-orphanization of GPR139 and GPR55, including the identification of sub-nanomolar
- GPCR Assay Strategy, Bias, and Translational Drug Discovery | Dr. GPCR Ecosystem
Marro describes a Gq coupled receptor program in which four lead series with sub nanomolar calcium potency Potency in the primary assay is not the same as efficacy in the animal Four lead series reached sub nanomolar chemokine receptors at GSK - 15:47 Doubting a career choice after a Nobel Prize announcement - 26:16 Sub nanomolar
