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Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor Biology National Institutes of Health – National Institute on Aging at the Johns Hopkins University Medical Center the highly-valued Odysseus Program Type I Program Grant to work as both the Adjunct Director of the VIB Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based Maudsley on the web Maudsley Lab LinkedIn Google Scholar ResearchGate Maudsley Lab on Facebook Receptor Biology

Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor Biology National Institutes of Health – National Institute on Aging at the Johns Hopkins University Medical Center the highly-valued Odysseus Program Type I Program Grant to work as both the Adjunct Director of the VIB Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based Maudsley on the web Maudsley Lab LinkedIn Google Scholar ResearchGate Maudsley Lab on Facebook Receptor Biology

Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor Biology National Institutes of Health – National Institute on Aging at the Johns Hopkins University Medical Center the highly-valued Odysseus Program Type I Program Grant to work as both the Adjunct Director of the VIB Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based Maudsley on the web Maudsley Lab LinkedIn Google Scholar ResearchGate Maudsley Lab on Facebook Receptor Biology

Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Atypical Structure

Home → Flash News → insights into g protein coupling preference from cryo em structures of gq bound PTH1R This new Nature Chemical Biology paper reveals cryo-EM structures of Gq-bound PTH1R—highlighting how implications for biased agonist design A critical advance for anyone working on class B1 GPCRs, bone biology

Committee Sponsors GPCR Retreat Program < Back to schedule Biased agonism at the GLP-1 receptor: from structure About Patrick Sexton " Patrick Sexton is a NHMRC Senior Principal Research Fellow and Director, ARC Centre Recently, his team has applied cryo-EM to elucidation of the structure and dynamics of GPCRs. Prof. is a 2022 Clarivate Analytics Highly Cited Researcher in two disciplines: Pharmacology & Toxicology; Biology

Demet Araç "Demet was an undergraduate at Bilkent University in Turkey, where she majored in Molecular Biology independent research career at the University of Chicago within the Department of Biochemistry and Molecular Biology Demet, who had studied various subjects including chemistry, physics, biology, and math, shared his interest Demet shared that his interest in science led him to study biology, genetics, and molecular biophysics biology and signaling assays.

Moro, that he truly saw how molecules could go beyond the bench and interact with biology in powerful The Moment Chemistry Met Biology Nicoli’s turning point came when he realized that molecules weren’t biology. 7. Modeling the Invisible: Olfactory Receptors Nicoli’s work centers on predicting ligand binding and receptor Alessandro Nicoli on the web Leibniz Institute for Food Systems Biology at the Technical University of

Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago; 2. Demet Araç "Demet was an undergraduate at Bilkent University in Turkey, where she majored in Molecular Biology She moved to the University of Texas Southwestern Medical Center at Dallas in 2000 to work with Dr. independent research career at the University of Chicago within the Department of Biochemistry and Molecular Biology , and I am formally trained as a chemical biologist."

Hamm 2 1 Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center Vanderbilt University, Nashville, TN 37232, USA 4 Peking University, China 5 Department of Anatomy and Cell Biology biology of membrane proteins. Her initial research centered around circadian clocks and melatonin synthesis in the avian retina; her Stanley Cohen Award “For Research Bringing Diverse Disciplines, such as Chemistry or Physics, to Solving Biology

Center, Rotterdam, The Netherlands" About Cheng-Chih Hsiao "2012-2015: PhD in Immunology, University Centre for Experimental Medicine, Institute for Biocehmistry and Molecular Cell Biology, University Medical , Munich 2015 - 2018 Postdoctoral fellow, Department of Adipose Tissue Biology, Institute for Diabetes Molecular Biology, Karolinska Institute, Sweden" Anastasia Georgiadi on the web Endocrine Pharmacology structure and function, and has evolved to encompass their roles in regulating immune cell response

From virtual screening of billions of molecules to leveraging AlphaFold for structure prediction, Jens biology—and where it still falls short Advice for junior scientists: what really matters when building biologists Early-career researchers exploring drug discovery Biotech leaders and R&D strategists Anyone interested in predictive modeling, AI in biology, or structure-function relationships About Jens Carlsson for collaborative science, Jens is a strong advocate for bringing together chemists, modelers, and biologists

About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Structure-based

GPCR Podcast Strategic Partners Translating computational approaches to GPCR biologists with Dr. He earned his PhD in Physics at the same university, focusing on in silico structural vaccinology and Now in a tenure-track position, his research spans the development of computational methods such as structure-based Scholar ResearchGate Bysky App : @ riccardocapelli.bsky.social Twitter X : @ ric_capelli Computational Structural Biology Enjoying the Dr.

New cryo-EM structures of GPR4 and GPR68 reveal how extracellular histidines act as proton sensors-trigger ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structural-basis-and-biased-signaling-of-proton-sensation-by-gpcrs-mediated-by-extracellular-histidine-rearrangement New cryo-EM structures of GPR4 and GPR68 reveal how extracellular histidines act as proton sensors-trigger ➡️ https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structural-basis-and-biased-signaling-of-proton-sensation-by-gpcrs-mediated-by-extracellular-histidine-rearrangement Yet, any pharmacologist who’s pushed beyond textbook theory knows: biology rarely plays fair.

Lukas Grätz "After a BSc in biology and a MSc in bioinformatics, I have been working in David Gloriam's branched out to multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure As a developer, and more recently the lead developer of GPCRdb my day-to-day work centers around the

GPCR Podcast Strategic Partners Gáspár Pándy-Szekeres About Gáspár Pándy-Szekeres " After a BSc in biology branched out to multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure As a developer, and more recently the lead developer of GPCRdb my day-to-day work centers around the

The explosion of biomedical data such as in genomics, structural biology, and pharmacology can provide G protein-coupled receptors (GPCRs) mediate a vast variety of critical biological processes and provide quantitative, and multi‐scale integration of these amounts of data to gain novel insights into receptor biology How can we best leverage these exciting new techniques in areas such as protein structure prediction,

currently a postdoc as a member of the personalized medicine cluster in Copenhagen and at the Institute of Biological Alexander has a big interest in the integration of large biomedical data in genomics, structural biology and pharmacoepidemiology with innovative computational methods to gain novel insights into receptor biology Alexander had a research sabbatical with Madan Babu at the MRC Laboratory of Molecular Biology in Cambridge

Martin Audet Structural biologist, pharmacologist, and a professor of pharmacology at Université de Sherbrooke the AudetLab located at the Institute of Pharmacology of Sherbrooke and is an emerging leader in the structural biology of G Protein-Coupled Receptors and passive transporters.

mechanisms of AGPCR signaling and function Structural Determinants Of GAIN Domain Autoproteolysis And details on CELSR proteins are sparsely available, precluding an integrative understanding of CELSR biology P., Shearer, Tanner, Sando, Richard C.*, and Araç, Demet* Department of Biochemistry and Molecular Biology , The University of Chicago Neuroscience Institute, Institute for Biophysical Dynamics, and the Center I study adhesion GPCRs using structural biology perspective and I am interested in how the large multidomain

Cardarelli is a drug development leader with extensive experience driving drug discovery teams in bringing biologics She has expertise in cell biology, pharmacology, translational medicine, oncology, immuno-oncology, immunology Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience issued U.S. patents including anti-PD-1 patents, 22 EP patents, and greater than 100 global patents centered

a Ph.D. degree in 2003 with a particular interest in the cardiovascular system by investigating the structure of the Angiotensin and Urotensin receptors through various biochemical approaches centered in the elucidation Boucard pursued postdoctoral training at the University of Texas Southwestern Medical Center in Dallas Mexico City to establish himself as an independent investigator integrating the department of Cell Biology

Fan is currently an associate professor of Pharmacology and Pathology and Cell Biology at Columbia University Qing is a structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit

Sri Kosuri Sri is a biologist that has helped build technologies, labs, and companies in synthetic biology He is passionate about developing more rational ways to understand and engineer biology. empirically exploring questions in protein biochemistry, human genetic variation, gene regulation, chemical biology , synthetic biology, and functional genomics. He is a Searle Scholar (2015), NIH New Innovator (2014), and received his ScD in Biological Engineering

Communications, which she joined in April 2020, following three years on the editorial teams of Nature Structural and Molecular Biology and Nature Biotechnology. Katarzyna handles submissions in structural biology, biophysics and biochemistry, with a particular focus

Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Leaving for City Center

, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA 5 O'Neal Comprehensive Cancer Center : Department of Biology, Ashoka University. Currently: University of Leipzig Mansi Tiwari: Department of Biology, Ashoka University. I joined University of Texas Southwestern Medical Center, for my postdoctoral training. I joined the Department of Biology at Ashoka University in 2020 as an assistant professor."

Why this matters How a chemist with zero biology training became a leader in GPCR probe design. Who should listen If you’ve ever: Navigated a project where the biology refused to match the textbook Collaborated across chemistry and biology and felt the translation gap firsthand… …this episode will his interest in ion channels, GPCR pharmacology, and the chemical strategies needed to probe complex biology His lab integrates synthetic chemistry, theoretical chemistry, cell biology, and imaging to understand

collaborative chemistry enabled in designing receptor-targeted fluorescent ligands The moment when structural tissue-specific engagement Who should listen Navigated complex datasets where interpretation depended on biological Robert Turner Professor of Diabetic Medicine at the University of Oxford , working within the Oxford Centre His group develops imaging and chemical biology tools to reveal how GLP-1 and GIP receptors operate within David Hodson on the Web Radcliffe Department of Medicine Islet Biology Lab University of Birmingham Enjoying