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Results found for "Ya-Tzu Li"
- Dr. GPCR Team | Dr. GPCR Ecosystem
<< Back to podcast list Dr. GPCR Podcast Strategic Partners Dr. GPCR Team About Dr. John Azietaku on the web LinkedIn Dr. GPCR About Ya-Tzu Li Ya-Tzu is a Master's student at the University of South Florida, utilizing large-scale In August, Ya-Tzu will continue her academic and research pursuits by beginning her PhD training in Medical Ya-Tzu Li on the web LinkedIn Dr.
- Dr. Nicolas Gilles | Dr. GPCR Ecosystem
<< Back to podcast list Dr. GPCR Podcast Strategic Partners Dr. Nicolas Gilles About Dr. His strongest expertise lies in therapeutic target identification and all the steps from venom manipulations When the pharmacological properties of these new ligands are deemed exceptional, a lead optimization Nicolas Gilles on the web Google Scholar LinkedIn Dr. GPCR Enjoying the Dr. GPCR Podcast? : The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening
- Terry's Corner is Officially LIVE! 🎉 This is your new go-to for mastering drug discovery pharmacology. No fluff, just clear, on-demand insights from Terry Kenakin. Building core expertise? Master dose-response, binding, kinetics, and foundational models. Driving drug discovery? Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter? Sharpen your edge with allosteric bias, residence time, and translational PK/PD. Learn on-demand, apply immediately: https://terrykenakin.com #DrGPCR #GPCR #pharmacology #TerrysCorner #DrugDiscovery | Dr. GPCR Ecosystem
Home → Flash News → Terry's Corner is Officially LIVE! TerrysCorner #DrugDiscovery Published on July 2, 2025 Category Terry's Corner Terry's Corner is Officially LIVE But what if the real opportunity lies in the chemical matter we throw at them?
- ep 175 with jens carlsson clip 3 | Dr. GPCR Ecosystem
For decades, molecular modeling focused on explaining — rationalizing why a ligand binds, why a mutation With tools like AlphaFold , his lab can now model receptor–peptide complexes in seconds — an achievement A good model doesn’t just match published structures; it forecasts new biology, new ligands, and new That’s where the future of GPCR research lies — not in describing the past, but in anticipating it.
- 💡 GPCR drug development doesn’t have to be a mystery! Learn from Dr. Terry Kenakin in this 4-week immersive course covering ligand development & pharmacology. 🔹 What you’ll learn: ✅ Drug Development Basics – Absorption, metabolism, PK principles ✅ Clearance & Distribution – Renal & hepatic clearance, key pharmacokinetics ✅ PK-PD Modeling – Predicting drug behavior, non-linear PK ✅ Early Drug Safety – Toxicity risks & drug interactions 📌 Spots are filling fast! Sign up today 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery | Dr. GPCR Ecosystem
Terry Kenakin in this 4-week immersive course covering ligand development & pharmacology. 🔹 What you – Renal & hepatic clearance, key pharmacokinetics ✅ PK-PD Modeling – Predicting drug behavior, non-linear Sign up today 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. Sign up today 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. But what if the real opportunity lies in the chemical matter we throw at them?
- We’re excited to announce our strategic partnership with Celtarys Research, a biotech company specializing in fluorescent ligand technologies and real-time, non-radioactive GPCR assays. This collaboration combines Dr. GPCR’s global platform with Celtarys’ innovative chemical biology tools, making it easier than ever for scientists to study ligand-receptor interactions, visualize binding, and accelerate drug discovery. We’re proud to welcome Celtarys to the Dr. GPCR ecosystem to support researchers worldwide and expand access to high-performance tools for GPCR-targeted therapeutics. ✳️Read the complete press release: https://www.ecosystem.drgpcr.com/post/dr-gpcr-and-celtarys-research-join-forces-to-expand-access-to-innovative-gpcr-tools #GPCR #DrGPCR #CeltarysResearch #DrugDiscoveryTools #FluorescentLigands #GPCRresearch #ScientificPartnership | Dr. GPCR Ecosystem
announce our strategic partnership with Celtarys Research, a biotech company specializing in fluorescent ligand with Celtarys’ innovative chemical biology tools, making it easier than ever for scientists to study ligand-receptor announce our strategic partnership with Celtarys Research , a biotech company specializing in fluorescent ligand with Celtarys’ innovative chemical biology tools , making it easier than ever for scientists to study ligand-receptor But what if the real opportunity lies in the chemical matter we throw at them?
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
Rottapel’s research interests lies in the elucidation of signal transduction pathways in cancer, immune The Rottapel Lab Ontario Institute for Cancer Research University of Toronto Pubmed Google Scholar LinkedIn
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Abhishek Kumar Singh Investigating The Role of ADGRB3 Loss of Expression in Brain Tumor Formation in Li-Fraumeni Scholar X (Twitter) Investigating The Role of ADGRB3 Loss of Expression in Brain Tumor Formation in Li-Fraumeni Syndrome Alex Torrelli-Diljohn Abstract "Li-Fraumeni syndrome (LFS) is a rare cancer predisposition Authors & Affiliations "Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong He is interested in working on Li-Fraumeni syndrome and helping patients afflicted with this condition
- Dr. Robert J. Lefkowitz | Dr. GPCR Ecosystem
<< Back to podcast list Dr. GPCR Podcast Strategic Partners Dr. Robert J. His legacy lies in the numerous discoveries he and his team made in the GPCR field and in all those who : The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening
- Forget one receptor at a time. Go big.Ep.167 of the Dr.GPCR Podcast with Tom Sakmar & Ilana Kotliar is about scaling GPCR research with multiplexing, miniaturization, and collaboration. The tools are built. The data is free. What will you ask next? 📲 Dive in: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRtraining #GPCRresearchcommunity #DrGPCR #GPCRdata | Dr. GPCR Ecosystem
But what if the real opportunity lies in the chemical matter we throw at them?
- Every receptor tells a story | Dr. GPCR Ecosystem
Michelle Halls unpacks how GPCR signaling isn’t just about ligand–receptor interaction. Michelle Halls unpacks how GPCR signaling isn’t just about ligand–receptor interaction. systems — where complexity is the key to precision. 🎧 Watch this moment from our conversation, then listen But what if the real opportunity lies in the chemical matter we throw at them?
- How do GPCRs sense pH changes? New cryo-EM structures of GPR4 and GPR68 reveal how extracellular histidines act as proton sensors-trigger activation and biased G protein coupling! Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structural-basis-and-biased-signaling-of-proton-sensation-by-gpcrs-mediated-by-extracellular-histidine-rearrangement #gpcr#drgpcr | Dr. GPCR Ecosystem
But what if the real opportunity lies in the chemical matter we throw at them?
- Trainee Symposium II
Back to schedule Trainee Symposium II Date & Time Thursday, November 2nd / 3:00 PM - 4:00 PM Title: Linking My primary research focus lies in gaining deeper insights into the structural mechanisms governing G protein engineering, receptor pharmacology, and structural biology to study how different types of ligands
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
2,3,*, Analisa Thompson Gray 2, Feyisayo Adegboye 2, Ainsley McDonald-Boyer 3, Fubiao Shi 1, Dianxin Liu 1, Jose Maldonado 5, Jiesi Feng 4, Yulong Li 4, Simon Alford 5, Julio E. The Department’s strengths lie in GPCR signal transduction and neuroscience, and she has expanded it She gave the Fritz Lipmann Lecture at ASBMB in 2001. " Heidi Hamm on the web The Hamm Lab Vanderbilt School of Medicine Pubmed Google Scholar LinkedIn Twitter Dr.
- ep 175 with jens carlsson clip 1 | Dr. GPCR Ecosystem
Their lab doesn’t just simulate receptor-ligand interactions after the fact; they aim to forecast receptor By integrating molecular docking, molecular dynamics, and machine learning, they design ligands with His team is candid about the limits of their models. This episode is essential listening for anyone thinking seriously about translational pharmacology and But what if the real opportunity lies in the chemical matter we throw at them?
- From Rare Earth Probes to Internalization Assays: The pHSense Story with Dr. Eric Trinquet | Dr. GPCR Ecosystem
. << Back to podcast list Dr. the IP-One kit, Tag-lite, and now, pH Sense. HTRF, the IP-One kit, and the Tag-lite platform into widespread use. His passion lies in turning cutting-edge probe chemistry into robust, scalable tools for drug discovery GPCR X Revvity Collaboration ⸻ Want more like this? Join the Dr.
- From Curiosity to Breakthrough: Ajay Yekkirala on GPCR Innovation | Dr. GPCR Ecosystem
. << Back to podcast list Dr. Curiosity to Breakthrough: Ajay Yekkirala on GPCR Innovation What if the key to safer, more effective drugs lies is the heart of scientific innovation Who Should Listen PhD students and postdocs exploring biotech careers Seeing the limits of traditional drug discovery, he later co-founded Superluminal Medicines, a company Ajay Yekkirala on the web Superluminal Medicines LinkedIn Tune in now to hear how asking “what if?”
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
species, we plan to adapt this technology for high-throughput screening of pharmacological compound libraries Stephanie Häfner on the web LinkedIn Scholz Lab Langenhan Lab bioSens-All: A Multiparametric BRET-Based Authors & Affiliations "Ana Lilia Moreno Salinas (2), Arturo Mancini (1), Raida Jallouli (2), Richard My expertise lies in exploring the biological properties and signaling pathways activated by aGPCRs, Ana Lilia Moreno Salinas on the web ResearchGate LinkedIn < Previous Session Next Session >
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
< Back to Full Agenda Session II AGPCR signaling pathways and trafficking Localization of putative ligands ADGRG6 Drives Proteolytic Processing, Trafficking And Signalling Pal Kasturi Localization of putative ligands Yuling Feng on the web LinkedIn The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial His research interest lies in understanding the molecular basis for human tumor development and how to ADGRG6 NTF has multiple extracellular domains like CUB, PTX, SEA, hormone binding domain, and the GAIN
- Lighting up a native pancreatic islet isn’t just a technical win it’s a shift in what GPCR imaging can reveal | Dr. GPCR Ecosystem
Home → Flash News → Lighting up a native pancreatic islet isn’t just a technical win it’s a shift in what GPCR imaging can reveal Lighting up a native pancreatic islet isn’t just a technical win — it’s variability Surface-pool selectivity — the pharmacologically relevant population Compatibility with live takeaways you’ll want to steal. 🔗 Read the blog : https://www.ecosystem.drgpcr.com/post/when-the-islet-lit-up-advancing-gpcr-imaging-in-native-tissue
- 10 GPCR pharmacology lessons. Zero fluff. Launching July 1, Terry’s Corner gives you the clarity and confidence to make better decisions—starting with: • The role of pharmacology in discovery strategy • Black & Leff’s operational model—finally made practical • Binding curves, orthosteric vs allosteric function, and real vs apparent affinity • Molecular dynamics and how they guide ligand design • Why Terry built this—and how it sharpens your next move 📅 Learn anytime. New course every week. 📬 Subscribe to The Kenakin Brief → https://www.terrykenakin.com #GPCRscience #drugdiscovery #TerrysCorner #GPCRpharmacology #ligandbinding | Dr. GPCR Ecosystem
orthosteric vs allosteric function, and real vs apparent affinity • Molecular dynamics and how they guide ligand Kenakin Brief → https://www.terrykenakin.com #GPCRscience #drugdiscovery #TerrysCorner #GPCRpharmacology #ligandbinding orthosteric vs allosteric function, and real vs apparent affinity 🟢 Molecular dynamics and how they guide ligand Kenakin Brief → https://www.terrykenakin.com #GPCRscience #drugdiscovery #TerrysCorner #GPCRpharmacology #ligandbindingv
- New biosensor technologies are shedding light on GPCR dynamics directly in cells, offering exciting possibilities for multiplexing and miniaturization! Curious about how these advances could impact drug discovery? Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! | Dr. GPCR Ecosystem
Home → Flash News → New biosensor technologies are shedding light on GPCR dynamics directly in cells, Published on October 24, 2024 Category GPCR Weekly News New biosensor technologies are shedding light
- 🚀 New Workshop: Practical Quantification of Allosteric Modulation Join Dr. Terry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery. Learn how to: ✔️ Identify, measure, and quantify allosteric properties ✔️ Apply functional allosteric models to determine mechanisms of action ✔️ Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025 ⏳ Registration deadline: April 18th 📍 Live on Google Meet 🔗 Register now: https://www.ecosystem.drgpcr.com/event-details-registration/practical-quantification-of-allosteric-modulation #GPCR #Allostery #DrugDiscovery #Pharmacology | Dr. GPCR Ecosystem
Terry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025 ⏳ Registration deadline: April 18th 📍 Live Terry Kenakin on May 1st, 2025 , for an advanced live workshop on allosteric modulators in GPCR drug Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025⏳ Registration deadline: April 18th📍 Live
- Autoantibodies that activate GPCRs? Wild—but real. Tom Sakmar & Ilana Kotliar break down the link between GPCR autoantibodies, long COVID, and disease signaling in Ep.167 of the Dr.GPCR Podcast This episode is a must if you're thinking diagnostics. 📲 Tap to listen: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRautoantibodies #GPCRdrugdiscovery #DrGPCR #Immunology | Dr. GPCR Ecosystem
Tom Sakmar & Ilana Kotliar break down the link between GPCR autoantibodies, long COVID, and disease signaling in Ep.167 of the Dr.GPCR Podcast This episode is a must if you're thinking diagnostics. 📲 Tap to listen Tom Sakmar & Ilana Kotliar break down the link between GPCR autoantibodies, long COVID, and disease signaling in Ep.167 of the Dr.GPCR Podcast This episode is a must if you're thinking diagnostics. 📲 Tap to listen
- 🚀 Science and finance aren't opposites—they’re partners. In this Ep.165 of the Dr.GPCR Podcast, Joe St. Germain & Chuck DeWeese reveal what it really takes to build sustainable startups and nonprofits behind the scenes. Grant accounting, character-first hiring, mission-driven growth—it’s all here! 🎧 Listen now: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
🎧 Listen now: Ep 165 with Chuck DeWeese & Joe St. 🎧 Listen now: Ep 165 with Chuck DeWeese & Joe St.
- Dr. GPCR University is officially back! 🎆 Join Dr. Terry Kenakin for "The Practical Assessment of Signaling Bias" workshop! 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling. ✳️Early Bird discounts for Premium Members! ➡️Register today at https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling
- This study adds a key piece to the puzzle of adhesion GPCR signaling. Understanding receptor-specific nuances, like the role of NTF cleavage, is crucial for decoding their functional outcomes. Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs/n-terminal-fragment-shedding-contributes-to-signaling-of-the-full-length-adhesion-receptor-adgrl3 #gpcr #drgpcr | Dr. GPCR Ecosystem
Understanding receptor-specific nuances, like the role of NTF cleavage, is crucial for decoding their Understanding receptor-specific nuances, like the role of NTF cleavage, is crucial for decoding their
- What are your thoughts on β2AR? Listen to Ep.163 of the @DrGPCR Podcast, where @DVeprintsev shares his thoughts and experiences about working with GPCRs, tips on framing your research correctly, and other insightful topics. Don’t miss out! ✳️https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #GPCRs #SciencePodcast #DrugDiscovery #Biotech #DrGPCR | Dr. GPCR Ecosystem
Listen to Ep.163 of the @DrGPCR Podcast, where @DVeprintsev shares his thoughts and experiences about Listen to Ep.163 of the @DrGPCR Podcast, where @DVeprintsev shares his thoughts and experiences about
- Registration & Coffee with light breakfast | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Registration & Coffee with light
- ⚠️ Registration Deadline today! This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection with Dr. Terry Kenakin. Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. | Dr. GPCR Ecosystem
GPCR to expand fluorescent ligand tools for GPCR drug discovery, connecting biotech startups and scientists Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. ✳️ Last chance








