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GPCR Retreat is an annual joint meeting with the Club des récepteurs à Sept Domaines Transmembranaires du Retreat partnered with the annual symposium of the Club des Récepteurs à Sept Domains Transmembranaires du Protein-Coupled Receptor Retreat held jointly with the Club des Récepteurs à Sept Domaines Transmembranaires du

In 2006, Bianca obtained a Doctoral Scholarship from the Fonds de Recherche du Québec en Santé.

how a headache neurologist redirected two decades of work Key Insights from the Conversation The yin-yang

advanced fluorescent probes developed specifically for working with endogenous GLP-1R and GIPR across a range Available across multiple spectral ranges for confocal, super-resolution, and intravital imaging. daLUXendin Family Fluorescent dual agonists for both GLP-1R and GIPR (daLUXendin544+ and daLUXendin660+), structurally

Mikel Garcia-Marcos "I was trained as a biochemist and molecular biologist during my Ph.D (2005) in Spain and Belgium, and subsequently as a cell biologist during my postdoc (2006-2011) with Dr. To achieve this goal, we use a wide range of established approaches (biochemistry, cell biology, genetics

This dual functionality—environmental sensing and compartment-specific signaling—offers a new layer of titles, with Yamina suggesting "Ancient Greek Chemistry and GPCRs"—a nod to Ian’s heritage and the wide-ranging

biochemistry from Leipzig University (Germany) being already fascinated by G protein-coupled receptors (GPCRs) due During my Ph.D. at the International Max Planck Research School “The Leipzig School of Human Origins” Quick recap Yamina and Claudia had a wide-ranging discussion about Claudia's work on metabolites and interest in attending a meeting about GPCRs and metabolism in the UK, but was unsure if she could make it due

During these four sessions, you'll dive into: Advanced pharmacokinetic modeling The Druglike Quality calcium mobilization: Cell type-dependent involvement of Gi, Gq, Gs proteins and protein kinase C Qin Wang

The discussion ranges across four decades of receptor pharmacology — from the era when the field debated sealed it: receptors 06:30 When the field debated whether opioid receptors were even proteins 11:31 The "dumb

run in the mountains, play with Tilly (a 9-year old retired greyhound), collecting mini shoes, and hang

end, her lab uses several computational structural biology tools and rational drug design approaches, ranging

identified physiological hormones of such under characterized ‘orphan’ receptors and functional probes for a range

In this wide-ranging conversation, he reflects on the mentors, failures, and bold questions that shaped

They are involved in several pathologies, ranging from neurological, oncological, degenerative, metabolic

Traditional β₂-adrenergic agonists can stimulate muscle growth and fat loss but lose effectiveness over time due My father and I went ice skating frequently during the winter. Months later, during winter, he cut a hole in the ice. I asked what he was doing.

. 🧱 Step 2: Plan Your Course Structure Decide how your course will flow — number of modules, duration

Sudarshan Rajagopal | Duke University The Spatiotemporal Revolution in GPCR Biology Biased Signaling What happens during the live discussion?

Sudarshan Rajagopal | Duke University The Spatiotemporal Revolution in GPCR Biology Biased Signaling

She first encountered olfactory receptors in the kidney during her postdoctoral training, and her lab

after attending a lecture on how the beta-adrenergic receptor in the heart is activated by adrenaline, during

Yaroslav Nikolaev is a scientist at InterAx Biotech with a dual background in biology and computation

GPCR during COVID — the career arc behind the ecosystem built for the field's unreached receptors. << Building during a pandemic is a design constraint, not a footnote. Dr. During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships presentation, I will walk you through my various career experiences and include the skills I learned during

Instructor Sudarshan Rajagopal is Associate Professor of Medicine in the Division of Cardiology at Duke University School of Medicine and Co-Director of the Duke Pulmonary Vascular Disease Center.

During our time together, Aaron and I discussed how using Twist Bioscience’s proprietary technology to

For her, the work isn't abstract: she spent five months staring at empty protein crystals during her During her PhD, Dr. receptor in phase 2 clinical trials 43:40 Five months of empty crystals 55:56 Rebuilding a research group during trained as a medicinal chemist in Italy, followed by a Ph.D. in computational medicinal chemistry, during

general-audience article on COVID pathobiology — an unexpected crossover for work that began as armchair science during Conversation The angiotensin imbalance hypothesis of COVID-19 pathobiology — AT1R overdrive versus ACE2/Ang , beta-2 receptors, and the asthma parallel The ethics of acting on conviction — off-label drug use during Insel realized no one had written criteria for how to decide about off-label use of a drug during a pandemic Type II pneumocytes, beta-2 density, and the asthma parallel 22:40 The ethics of off-label drug use during

Terry Hebert on why challenge trials weren't ready, what it takes to hold a GPCR signaling lab together during Scientific Themes of the Conversation Lab continuity during institutional shutdown — What it takes to

Pineyro, whose husband remained in Uruguay for the duration of the shutdown, the scientific work and The most striking observation in the conversation: lab members who rarely spoke up during in-person meetings Running a lab during the pandemic was rarely just a scientific problem.

carrying a personal loss in New York and leading a cancer center building that operated at 93% capacity during That dual lineage — extramural academic and intramural NIH — shapes how he thinks about research infrastructure architecture of a research lab under constraint The contract between scientific leadership and trainees during Gutkind describes operating his cancer research building at 93–94% capacity during the early pandemic Gutkind argues the scientific community grew closer during the pandemic, not further apart — the physical

of being a scientist Key Insights from the Conversation Ten billion dollars vanishes every year into duplicate