Search Results

After years of living with unresolved pain following surgery for a pilonidal cyst, Alex was left without This is a story about how chronic pain doesn't just shape lives — it reshapes careers. Mike Caterina on pain mechanisms in the peripheral nervous system. ______ Keyword Cloud: GPCR research community , chronic pain , GPCR drug discovery , GPCR scientist network , pain neuroscience

Watch Episode 170 What We’re Missing in Pain Research In GPCR drug discovery, receptors typically steal very interesting phenotype the lab found where, as a mouse was starting to enter what we consider the chronic models and hints that RGS proteins could modulate pain chronification itself . Whether working on opioid withdrawal, addiction vulnerability, or chronic pain, GPCR-related signaling pain. ___________ Keyword Cloud: RGS4 , GPCR data platform , GPCR training program , pain research ,

Watch Episode 166 Pain management is broken. And Benjamin Clements is on a mission to fix it. In fact, one of their recent neuroma pain studies showed a tenfold increase in methadone potency. That’s huge.” – Ben Clements By combining chronic pain models with receptor-level pharmacology, Ben Beyond Acute Pain: Into the Chronic Unknown Opioids work well for acute pain. Chronic pain? pain

Strategy: From Personal Pain to Scientific Purpose Dr. pain following repeated surgeries for a pilonidal cyst. pain, epigenetics, translational models. Venetia Zachariou's lab to study the effects of chronic pain and addiction/withdrawal on the mesocorticolimbic pain and affective comorbidities.

GPCR Title: Characterization of Novel Opioid-Neurotensin Bifunctional Ligands Designed to Target Pain interested in characterizing novel G protein-coupled receptors (GPCRs) ligands for the treatment of chronic pain but also in deciphering cellular signaling pathways associated with the physiological effects observed

“We’re enhancing the powerful pain-relieving effects of opioids while limiting respiratory depression He is particularly excited by the novel application of PAMs in chronic and neuropathic pain models , Discovering breakthrough results in neuroma pain models via a spontaneous collaboration. pain and opioid use disorder. pain.