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- Irreversible Drugs, Real Control: Design for Durable Target Engagement
Over 50% Discount at Checkout Get Yearly Access On-Demand Now — Free 7 Day Trial ➤ DrGPCR Podcast: Jens Carlsson on Predictive Modeling Prediction over explanation—that’s the shift. Jens Carlsson shares how structure-based design, molecular dynamics, and smart collaboration turn models
- Assay Volume Control: Your GPCR Drug Discovery Power Lever
Jens Carlsson (Uppsala University) joins Yamina to explore how computational modeling is evolving from
- AlphaFold’s Breakthrough in GPCR Research: Revolutionizing Discovery, Yet Awaiting Experimental Proof
relies on using the known structure of a homologous protein as a template to model the target protein ( Carlsson References: Carlsson, J. et al.
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
For example, Carlsson et al. (2010) utilised structural information and virtual ligand screening to discover Carlsson, J., Yoo, L., Gao, Z. G., Irwin, J. J., Shoichet, B. K., & Jacobson, K. A. (2010).
- Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024
: Congrats to: Ya-Tzu Li , our notable contributor, for her superb undergrad paper along with Hao-Jen
- Ode to GPCRs
transduction.[47] The 2000 Nobel Prize in Physiology or Medicine went to Eric Richard Kandel, Arvid Carlsson , and Paul Greengard for research on signal transduction in the nervous system.[48–54] Carlsson won the Arvid Carlsson – Facts - NobelPrize.org. https://www.nobelprize.org/prizes/medicine/2000/carlsson/facts
