He also integrates concepts like sex differences , epigenetic inheritance , and neuroimmune crosstalk _______ Keyword Cloud: GPCR podcast , pain modeling , GPCR online course , translational research , neuroimmune signaling .

GPCR Allosteric Modulators as Novel Intracellular Molecular Glues Classic models explain biased signaling PCO371 promotes G protein signaling while inhibiting arrestin recruitment through intracellular binding Reserve your spot ➤ iPSC-Derived Systems for GPCR Signaling and Translation Heterologous systems such This limitation affects how signaling data can be interpreted when receptor behavior depends on cell type, signaling complex assembly, and disease biology.

The bar, made visible: GeneTex’s GPRC5A antibody gives a clean signal in wild-type cells (left) that during her own PhD she had built a knockout mouse and could never find an antibody that gave an honest signal

< Back The spatiotemporal organization of GPCR signalling September 10, 2026 10 AM - 11:30 AM EST 🔒 Introduction GPCR signaling is organized in space and time. This Masterclass examines the spatiotemporal organization of GPCR signaling and the optical methods that imaging by FRET, BRET, and single-molecule microscopy, and signaling on internal membranes including His Masterclass brings this single-molecule, imaging-driven view of receptor signaling directly to Dr

. << Back to podcast list Strategic Partner(s) How Lipid Rafts Organize GPCR Signaling This episode features database and reviews key findings from his research on D1 receptor desensitization and GRK isoform signaling Why This Matters How lipid raft microdomains selectively regulate GPCR signaling and internalization protein-coupled receptors and D1 receptor regulation—work that sparked his ongoing engagement with receptor signaling

GPCRs Do Not Produce a Single Signal Dr. Activation of a receptor can generate multiple signaling pathways, and different ligands can bias signaling Absence of a Signal Can Be a Discovery One of Dr. “People think a receptor produces one signal. In reality, a receptor produces many signals.” But GPCRs activate multiple signaling pathways simultaneously.