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How to Use Statistical Methods to Strengthen Every GPCR Drug Discovery Decision

White background with molecular structures and "From Scatter to Signal: Trust the Stats." Logo in corner, abstract patterns.
GPCR research requires turning data into insights for drug discovery

Hi GPCR Friends,


Every week, critical decisions in GPCR research hinge on subtle shifts in data. Trusting your eyes—or tradition—can cost time, money, and credibility.


That’s precisely why Terry’s Corner delivers this week: practical, statistical tools that let you move from “I think” to “I know.”



Breakthroughs this week: Why Everyone’s Talking About Metabolic GPCRs; GPS for proteins: Tracking the motions of cell receptors; A Better Way to Treat Obesity; Unlocking the pharmacological potential of antibodies.



🔍 This Week in Dr. GPCR Premium: Sneak Peek


Your weekly edge — curated signals you won’t find on public feeds.


  • Industry insights: Metabolic GPCRs climbing the spotlight; new tools tracking receptor motion; obesity drug strategies shifting; antibody pharmacology opening fresh doors.

  • Upcoming events: Major GPCR-focused symposiums and translational meetings are on the horizon — shaping agendas and collaborations across Europe and the U.S.

  • Career opportunities: Leadership-level roles in clinical operations and translational science, alongside multiple GPCR-focused postdoc positions.

  • Must-read publications: A structural modeling study revealing non-canonical mechanisms of chemokine-driven receptor activation.





Terry's Corner – Curve Shifts Don’t Lie, But Your Eyes Might



In early drug discovery, “those curves look different” is not enough. This week, Dr. Terry Kenakin walks you through which statistical tests actually answer the question you think you’re asking—so you can start making confident decisions.


From t-test, ANOVA, F-test selection to power analysis that prevents underpowered studies, this module hands you a practical framework to validate differences, confirm subtle shifts, and benchmark your results against literature or across assay types.


  • Avoid wasted resources: Stop relying on “n=3” by default. Power analysis tells you exactly how many replicates you need for 95% confidence.

  • Eliminate subjective calls: From t-tests to ANOVA and F-tests, know which tool to apply when, so debates about “what the graph says” end with evidence.

  • Validate with confidence: Benchmark your results against literature standards and confirm whether your assays hold up—or diverge in meaningful ways.


Premium Members get a 50%+ discount when they join Terry’s Corner.


🚨 First-ever Live AMA with Dr. Kenakin happens this month—exclusively inside Terry’s Corner. Bring the curve you’re debating. Ask. Challenge. Get an answer you can defend.





Dr. GPCR Podcast – Ajay Yekkirala on GPCR Innovation



In this episode, Dr. Ajay Yekkirala shares the journey from academic pharmacologist to biotech entrepreneur—bridging curiosity, AI/ML, and translational medicine.


  • Learn entrepreneurial lessons rarely shared with postdocs.

  • Understand how AI/ML and GPCR biology meet to unlock safer drugs.

  • Gain career inspiration from Ajay’s bold questions and pivots.





GPCR Happy Hour – Boston, September 2025


Space is limited. Big ideas aren’t. When the global biotech crowd lands in Boston for Discovery on Target.


This is where the real conversations begin—made possible with the support of NIS, Proteos, and Axxam . Expect a curated room of scientists, leaders, and investors ready to compare notes, spark collaborations, and accelerate programs.


  • Forge high-value connections in an intimate setting.

  • Be part of the nonprofit mission to unite the GPCR community.

  • Don’t miss the conversations that will ripple long after the conference.






Why Dr. GPCR Premium Membership Gives You an Edge



Premium delivers curated, noise-free intelligence every week: deep-dive expert lectures, classified industry news, priority event alerts, job opportunities, and insider commentary—designed to help you move faster, smarter.


Where others sift through noise, Premium gives you distilled, relevant, and actionable insights. Whether you’re in discovery, translation, or strategic leadership, Premium ensures you never fall behind.



FAQ: Premium Membership



🔹 What’s included?

The complete Weekly News digest, curated jobs, upcoming events, classified GPCR publications, exclusive on-demand expert lectures, and member-only discounts.


🔹 Who is it for?

GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need career-relevant intelligence to stay ahead.


🔹 Why now?

The pace of GPCR innovation is accelerating. Those who act on the right signals today will lead tomorrow’s breakthroughs—and avoid delays others won’t see coming.


👉 Don’t Fall Behind—Access the Edge You Need




What our members say


🗣️ "The content had enough depth to satisfy the hunger for theory while being full of practical knowledge." — DrGPCR University Attendee

Stay informed. Stay connected. Stay ahead.


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