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- University | Dr. GPCR Ecosystem
Advance your GPCR research career with Dr. GPCR University. GPCR University A nonprofit created by scientists, for scientists—bringing the global GPCR community GPCR University? Dr. G protein-coupled receptors (GPCRs). GPCR University Masterclasses?
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Conformational And Functional Coupling Between Extracellular and Transmembrane Regions of a Holo-Adhesion GPCR Kordon Deorphanization Of The Adhesion GPCRs GPR110 and GPR116 Tingzhen Shen Self-Cleavage of GPR110 Activity In The G12/13 Pathway Júlia Rosell Endocytic Cues Determine the Signaling Profile of Adhesion GPCR Kordon on the web Araç Laboratory at UChicago Deorphanization Of The Adhesion GPCRs GPR110 and GPR116
- Weekly News October 23 | Dr. GPCR Ecosystem
GPCR Weekly News - Oct 23 - The Power and Peril of Irreversible Drugs Published on October 23, 2025 Category GPCR Weekly News This week’s Weekly News breaks down how to control target engagement—so duration, penetration irreversible” in real systems, anticipating PK/PD decoupling, and using k_inact/K_I when Ki falls short. 🔹 Podcast #DrGPCR #GPCR Previous Next Recent Articles
- Our Sponsors for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Meet the sponsors who make the Adhesion GPCR Workshop 2024 possible, supporting global collaboration and innovation in GPCR research. Home Registration Full Agenda Venue Travel Tips Sponsors Special Issue on Adhesion GPCRs OUR SPONSORS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Sponsor Us Platinum Sponsors Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR
- Donation for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Support the Adhesion GPCR Workshop 2024 with a donation. Help advance GPCR research, enable education, and connect the scientific community. DONATIONS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Our Sponsors
- Advanced data analysis for GPCR pharmacology | Dr. GPCR Ecosystem
Advanced data analysis for GPCR pharmacology Dr. Samuel Hoare Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird access - Recordings will be available < Back to GPCR courses Watch recording Your Instructor Dr.
- About Dr. GPCR Ecosystem | Uniting the GPCR Community to Advance Drug Discovery
GPCR unites researchers, industry, and partners to accelerate GPCR science and drug discovery—through GPCR Ecosystem We unite the GPCR community to advance drug discovery. We bring the GPCR community together to fuel GPCR drug discovery—one receptor at a time. across the global GPCR ecosystem. : We verify GPCR relevance during onboarding to preserve focus and quality.
- CRO Advisory | Dr. GPCR Ecosystem
GPCR Ecosystem. Get guidance, strategies, and insights to optimize your GPCR research and drug discovery projects. Get in touch Connect LinkedIn Podcast Dr. GPCR Calendly ©2023-2025 All rights reserved by FindYooour, LLC & Dr. GPCR Corp Proudly created with Wix.com
- Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Plenary Lecture Identification and Functional Characterization of Adhesion GPCRs Our first main research aspect is the identification of endogenous ligand of GPCRs. Our third main research aspect is working mechanism of GPCR. (Cell 2021, 2023, Nature 2023b), bile acids or its derivatives by GPCRs (Nature 2020)."
- Logo Contest for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Submit your design to represent the Adhesion GPCR Workshop and inspire our global community. LOGO CONTEST Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register Rules Artist-scientists must be registered to attend the adhesion GPCR workshop 2024 in Mexico City. Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program.
- Dr. GPCR University Vault | Dr. GPCR Ecosystem
Quickly get up to speed on new GPCR targets and mechanisms, and gain a competitive edge with our extensive University Vault: The Ultimate On-Demand GPCR Learning Library Every talk inside the University Vault represents years of research, collaboration, and innovation that continue to shape the GPCR field. More Benefits What Scientists Appreciate The most comprehensive library of GPCR knowledge online. The University Vault is a great way to keep up with academic progress and find new GPCR therapies.
- Summit | Dr. GPCR Ecosystem
Join the forefront of GPCR research at the Dr. GPCR Summit! Uncover groundbreaking insights in GPCR science together. Learn more. Dr. GPCR Summit We live in a new world, and we think it's an opportunity to try new things and use current technologies to help us connect and spread scientific advances in the GPCR field. Our goal is to allow everyone in the GPCR community to get access to the talks through the entire length
- GPCR Courses | Dr. GPCR Ecosystem
Discover top GPCR Courses for your educational journey. GPCR Community builder for scientists with expertise in GPCR project strategy and translational applications As a member, you can access: Dr.GPCR Podcast videos Live GPCR events Weekly classified GPCR news Contributor Private groups 30+ Symposia recorded talks GPCR Job listings GPCR Event listings Direct access to members the world's top GPCR experts.
- Affiliate Policy | Dr. GPCR Ecosystem
GPCR Ecosystem. GPCR Ambassador Program Dr. GPCR, Corp., (“Dr. GPCR”, "DrGPCR", "Doctor GPCR", "Ecosystem Dr. GPCR", "EcosystemDrGPCR". Dr. GPCR”, "DrGPCR", "Doctor GPCR", "Ecosystem Dr. GPCR", "EcosystemDrGPCR". Dr. GPCR”, "DrGPCR", "Doctor GPCR", "Ecosystem Dr. GPCR", "EcosystemDrGPCR". Dr.
- New cryo-EM insights reveal how extracellular domains communicate with transmembrane regions in holo-adhesion GPCRs, uncovering mechanisms behind receptor activation. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com /adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function #gpcr #drgpcr Published on January 7, 2025 Category GPCR Weekly News New cryo-EM insights reveal how GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com #gpcr #drgpcr Previous Next Recent Articles
- A GPCR imaging breakthrough that didn’t start in a grant proposal | Dr. GPCR Ecosystem
A collaboration between chemistry and biology sparked a GPCR imaging breakthrough, leading to new chemical Home → Flash News → A GPCR imaging breakthrough that didn’t start in a grant proposal A GPCR imaging experiments, the pivot to chemical probes, and the trust-driven partnership that sparked a new era in GPCR reading. 🔗 Read the full story : https://www.ecosystem.drgpcr.com/post/how-collaboration-sparked-a-gpcr-imaging-breakthrough-in-chemical-biology
- Travel Tips for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
TRAVELING TIPS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register DO's Airfare and other travel arrangements are the full responsibility of aGPCR Workshop 2024 attendees. POSTER PRINTING Poster printing is the full responsibility of aGPCR Workshop 2024 attendees. Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program.
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Session VI AGPCRs shaping the nervous system ADGRCs in glutamatergic synapse His group has been particularly interested in the role adhesion GPCRs play in glioblastoma biology and I initially became interested in GPCR signal transduction during my graduate training in the Department GPCR < Previous Session Next Session >
- A large-scale analysis of GPCR molecular dynamics reveals hidden allosteric sites and lateral gateways, unlocking new possibilities for drug discovery. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/large-scale-investigation-of-gpcr-molecular-dynamics-data-uncovers-allosteric-sites-and-lateral-gateways #gpcr#drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com /structural-and-molecular-insights-into-gpcr-function/large-scale-investigation-of-gpcr-molecular-dynamics-data-uncovers-allosteric-sites-and-lateral-gateways #gpcr#drgpcr Published on March 17, 2025 Category GPCR Weekly News A large-scale analysis of GPCR molecular GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https:// www.ecosystem.drgpcr.com #gpcr#drgpcr Previous Next Recent Articles
- master gpcr pharmacologic models before its too late | Dr. GPCR Ecosystem
Home → Flash News → master gpcr pharmacologic models before its too late Published on July 11, 2025 Category GPCR Weekly News Most GPCR teams aren’t failing because of bad science. This week’s GPCR Weekly News helps you fix that. Yamina’s Corner exposes the silent drift killing GPCR programs (and how to reverse it). utm_content=bufferd9b30&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer #GPCR #Pharmacology
- Abstract Submission Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Submit your abstract for the Adhesion GPCR Workshop 2024. Share your research, connect with experts, and be part of the leading GPCR scientific community. ABSTRACT SUBMISSION Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Submit your 2024 [ Registration extended until September 15th ] Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR Workshop 2024 and its preliminary program.
- Retreat | Dr. GPCR Ecosystem
GPCR Retreat — an immersive event uniting scientists, biotech leaders, and innovators in GPCR research GPCR Retreat - Coming Soon - Please tell us your thoughts about scientific gatherings by filling out
- encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network | Dr. GPCR Ecosystem
Home → Flash News → encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network Published on July 7, 2025 Category GPCR Weekly News How do chemokines and GPCRs decode selectivity conserved and variable sequence–structure elements govern interaction logic across 46 chemokines and 23 GPCRs unstructured regions ♦️ Includes a web tool + viral chemokine engineering demo This is a must-read for GPCR ligand engineers. ➡️ Read the paper: https://www.cell.com/cell/fulltext/S0092-8674(25)00398-8 #DrGPCR #GPCR
- Biotech Growth | Dr. GPCR Ecosystem
How I Help Biotechs Accelerate GPCR Discovery with Clarity, Speed & Confidence Decisions, Not More Data Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution Get in touch Connect LinkedIn Podcast Dr. GPCR Calendly ©2023-2025 All rights reserved by FindYooour, LLC & Dr. GPCR Corp Proudly created with Wix.com
- Game-changer for GPCR research! 🔬🧪 Molecular glues offer a new way to fine-tune receptor signaling, opening doors for next-gen drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/reviews/molecular-glues%3A-a-new-approach-to-modulating-gpcr-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com /reviews/molecular-glues%3A-a-new-approach-to-modulating-gpcr-signaling-bias #gpcr #drgpcr Published on February 17, 2025 Category GPCR Weekly News Game-changer for GPCR research! GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https:// www.ecosystem.drgpcr.com /reviews/molecular-glues%3A-a-new-approach-to-modulating-gpcr-signaling-bias #gpcr #drgpcr Previous Next
- Explore / Organizations | Dr. GPCR Ecosystem
Discover how organizations in the GPCR field can leverage the Dr. GPCR Ecosystem to enhance their impact. Learn more about the benefits today! Become Dr. GPCR Strategic Partner Request Your Quote How Organizations can benefit from Dr. GPCR Ecosystem? the Ecosystem know and meet your customers at these events Discover Job Listings Looking to hire a GPCR GPCR Ecosystem.
- Illuminating Functional Selectivity and Allosterism at GPCRs.
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Illuminating Functional Selectivity and Allosterism at GPCRs. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- The GPCR world is waiting to see YOU. Update your profile today and be part of the biggest GPCR community in the world 🌏 ✳️Visit https://www.ecosystem.drgpcr.com/account/my-account and share your updated information 😉 #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → The GPCR world is waiting to see YOU. /account/my-account and share your updated information 😉 #gpcr #drgpcr Published on February 11, 2025 GPCR Profiles The GPCR world is waiting to see YOU. Update your profile today and be part of the biggest GPCR community in the world 🌏 ✳️ Visit https:// www.ecosystem.drgpcr.com/account/my-account and share your updated information 😉 #gpcr #drgpcr Previous
- Departure | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Session V | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Autoproteolysis And Cleavage Resistance Of Adhesion G Protein-Coupled Receptors Fabian Pohl Abstract "The GPCR Many ADGRs are autoproteo-lytically cleaved at the GPCR proteolysis site (GPS), an HXS/T motif within ) are a family of 32 mammalian proteins with a defining conserved GPCR autoproteolysis inducing (GAIN ) domain that catalyzes receptor self-cleavage at a GPCR proteolysis site (GPS).



