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- How Early Strategic Decision Making Creates Alignment and Better Results
Tradeoffs feel intentional rather than painful.
- đź“° GPCR Weekly News, June 19 to 25, 2023
Methods & Updates in GPCR Research A coiled-coil-based design strategy for the thermostabilization of the Gliovascular Unit of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research
- X4 slashes pipeline, lays off staff just three weeks after netting a $55M PIPE
The Boston biotech revealed Wednesday afternoon that it would downsize its research to focus on its lead
- Function and structure of bradykinin receptor 2 for drug discovery
review, we summarize the structure and function of B2R in relation to drug discovery and discuss future research
- Molecular insights into psychedelic drug action
desire for additional approaches to mental health care, incremental progress in basic and clinical research
- Molecular targets of psychedelic-induced plasticity
August 2022 "Psychedelic research across different disciplines and biological levels is growing at a
- Tectonic Therapeutic Strengthens Leadership Team
therapies (G-Protein Coupled Receptors), today announced the promotion of Senior Vice President, Head of Research
- Neurotransmitters: Potential Targets in Glioblastoma
neurotransmitter receptors have shown great potential for inhibiting GBM growth and development, requiring further research
- đź“° GPCR Weekly News, January 8 to 14, 2024
July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Researcher in Structural Biology NEW Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist Associate
- 4GPCRnet, September 26-29, 2022. Leipzig, Germany
Four of the biggest European networks on GPCR research (COST Actions Adher’n Rise and ERNEST plus DFG-funded
- GPCR Happy Hour – Boston, Sept 2025
Our mission is simple: bridge science and industry  by connecting researchers, biotech, CROs, and pharma electrophysiology platform, iPSC-derived models, optogenetics, and high-content screening techniques such as cell painting
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
cannot adequately predict protein structure (Jumper et al., 2021) ); 3) the same limitation holds when searching The future According to the authors, the future of AI relies in 6 main areas: 1. Automated tools for researchers: AI solutions which bring together theoretical, computational, and experimental Instead, it complements and assists researchers in the GPCR drug discovery process.
- Septerna emerges with $100M to spark 'second golden age' of prolific drug target GPCR with ...
Better known as GPCR, the fruitful research space has led to more than 700 approved drugs over previous Nobel laureate Robert Lefkowitz, M.D., has 50 years of experience with the target and analogizes the search
- Targeting Intracellular Allosteric Sites in GPCRs
Recent advances in structural biology have allowed researchers to visualize the binding of allosteric Allosteric modulation is gaining prominence in GPCR therapeutics, with the discovery of an intracellular
- Understanding Biased Signaling in GPCRs
live masterclasses, full replays, and access to the complete Masterclass Library, alongside curated research
- đź“° GPCR Weekly News, January 16 to 22, 2023
Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news Methods & Updates in GPCR Research Mapping of structural arrangement of cells and collective calcium
- Community guidelines for GPCR ligand bias: IUPHAR review 32
requires that we now characterize physiological signalling not just by receptors but by ligand-receptor pairs The guidelines will aid consistency and clarity, as the basic receptor research and drug discovery communities
- Hear the sounds: the role of G protein-coupled receptors in the cochlea
The research of GPCRs in the cochlea is essential for the understanding of the cochlea development, hearing
- Michel Bouvier appointed Knight of the Ordre national du Québec
Michel Bouvier, Chief Executive Officer of IRIC, Principal Investigator of the Molecular Pharmacology Research
- đź“° GPCR Weekly News, March 20 to 26, 2023
Every week, we send you the most relevant news, research, and advancements in the field. For Dr. Methods & Updates in GPCR Research The application of targeted protein degradation technologies to G
- GPCR Therapeutics Expands Scientific Advisory Board
with an innovative approach to drug discovery based on targeting G Protein Coupled Receptors (GPCR) pairs Jon Wigginton will provide scientific expertise to support the company’s research and clinical development
- Domain Therapeutics Raises $42m Series A Financing
STRASBOURG, France & MONTREAL- Domain Therapeutics, a biopharmaceutical company specializing in the research
- C3aR plays both sides in regulating resistance to bacterial infections
Specifically, previous research has identified mechanistically distinct and cell type–specific roles
- Radioligands vs. Fluorescent Ligands: Binding Assays
Understanding receptor-ligand interaction is key in drug discovery and biomedical research.
- Dopamine D 1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior...
importance of functional selectivity/biased signaling has led to the discovery of biased compounds as both research A major pan-receptor focus has been to identify GPCR-selective ligands that have bias in G protein-dependent
- Misread the Curve, Misjudge the Drug: Rethinking Antagonism in GPCR Pharmacology
Why now:  GPCR research is accelerating—and the projects that succeed will be those built on clear, accurate
- Immunomodulatory Role of Neuropeptides in the Cornea
As research in this area expands, further insights are made into the role of neuropeptides and their
- Dr. Adriano Marchese - Dr. GPCR Podcast
Learn about his remarkable career and research in #GPCR signaling and trafficking.
- Comparative study of neuropeptide signaling systems in Hemiptera
This research provides more knowledge on neuropeptide systems and sets the groundwork for the creation
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
remaining non-sensory receptors, with functions more readily linked to pathology, are currently the main cell surface, or because they have an enhanced capacity to elicit receptor internalization, thereby gaining The Future of GPCR Research GPCRs are a very important class of drug targets, but despite historical Orion has entered a strategic research collaboration with Peptilogics, a US-based AI drug discovery company 17706–17711. https://doi.org/10.1073/pnas.0805098105 · Development and use of new technology to gain







