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- Welcome Reception and Poster Session 1
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Poster Session 1 Date & Time Thursday, November 2nd / 5:30 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Biased agonism at the GLP-1 receptor: from structure to animal models of disease
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to He is a leader in the study of GPCRs. Recently, his team has applied cryo-EM to elucidation of the structure and dynamics of GPCRs. Prof. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- Structure-based discovery of functionally selective 5-HT1A receptor agonists
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Peter Gmeiner has been spokesman of the Research Training Group "Medicinal Chemistry of Selective GPCR GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Think βCGRP is just αCGRP’s understudy? Think again. New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor family, challenging the long-held assumption of redundancy. 🔬 A closer look reveals differences in G protein coupling, second messenger production, and receptor trafficking. 📊 This could reshape how we understand CGRP-related physiology—and how we target it in drug design. 🧠 Pain, inflammation, metabolism: the implications go far beyond signaling bias. 🔗 Read the full paper in Biochemistry: Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR #CGRP #DrugDiscovery #Pharmacology #SignalTransduction #Neuropeptides | Dr. GPCR Ecosystem
Read the full paper in Biochemistry: Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR #DrugDiscovery #Pharmacology #SignalTransduction #Neuropeptides Published on June 16, 2025 Category GPCR Read the full paper in Biochemistry : Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR
- Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Michel Bouvier working on the topic of GPCR dimerization/oligomerization. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Complex Allosteric Cannabinoid Receptor Pharmacology
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Ever wondered how we perceive bitterness? 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor, bound to the drug flufenamic acid (FFA) and its signaling partner gustducin! 🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound design. 🧪✨ Learn more about this exciting breakthrough in bitter taste signaling. | Dr. GPCR Ecosystem
Published on December 5, 2024 Category GPCR Weekly News Ever wondered how we perceive bitterness? receptor-activation-and-signaling/a-bitter-anti-inflammatory-drug-binds-at-two-distinct-sites-of-a-human-bitter-taste-gpcr 3ecb-4719-8ba3-974d17e9f596&utm_source=so&utm_medium=mail&cid=79a6b35e-7ba6-44a0-863b-0842f5a5cfd3 #gpcr
- Dopamine-Mediated Motor Recovery after Ischemic Stroke
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to developing the translational component of our research to capitalize on the druggability potential of GPCRs GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Using food perception and bioamine signaling networks to slow aging
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Fresh, Fresh, GPCR News ❇ Feb 17 - 23, 2025 | Dr. GPCR Ecosystem
. 🚀 Develop New GPCR Skills Join Dr. Classified GPCR News Let’s dive into the Classified GPCR News from February 17th to 23rd, 2025 Industry Papers Special Issue on Adhesion GPCRs GPCR Events, Meetings, and Webinars March 19, 2025 | Advancing signaling and drug discovery Symposium & Workshop - Brazil NEW April 1 - 3, 2025 | 2nd Peptide-Based A force-sensitive adhesion GPCR is required for equilibrioception GPCR Activation and Signaling Extensive
- C-Principles of Pharmacology in Drug Discovery 1 | Dr. GPCR Ecosystem
Application of this knowledge to determine the mechanism of action of new GPCR ligands. The required elements of a comprehensive and effective GPCR Discovery. Modules: October 3rd: GPCR Project Initiation and Design for Discovery of New Molecules. October 17th: Agonists and Efficacy: A New World of GPCR Efficacies / Biased Signaling. GPCR and the offered resources in my work sphere Anonymous Dr.
- Targeting adenosine signaling for immuno-oncology
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to immunotherapies, and member of the SAB of Domain Therapeutics, a biopharmaceutical company focused on GPCR GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- ama session sept 18 post 3 | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/terry-corner ✳️ Next AMA Session: ⚠️ Today, Oct 30 | 12–1 PM EST #GPCR
- Distinct sub-cellular signal propagation as a component of functional selectivity
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to He is a world-renowned expert in the field of cell signaling and GPCRs and made seminal contributions GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Your GPCR Order Has Arrived! ❇ Feb 10 - 16, 2025 | Dr. GPCR Ecosystem
< Back Your GPCR Order Has Arrived! Classified GPCR News Let’s dive into the Classified GPCR News from February 10th to 16th, 2025 Industry Papers NEW Special Issue on Adhesion GPCRs GPCR Events, Meetings, and Webinars March 19, 2025 | Advancing and drug discovery Symposium & Workshop NEW April 2 - 3, 2025 | New therapeutic modalities: Transforming mechanosensing GPCR Activation and Signaling Lineage-Specific Class-A GPCR Dynamics Reflect Diverse
- A journey from Duke to McGill along the dopamine circuit
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- 10 GPCR pharmacology lessons. Zero fluff. Launching July 1, Terry’s Corner gives you the clarity and confidence to make better decisions—starting with: • The role of pharmacology in discovery strategy • Black & Leff’s operational model—finally made practical • Binding curves, orthosteric vs allosteric function, and real vs apparent affinity • Molecular dynamics and how they guide ligand design • Why Terry built this—and how it sharpens your next move 📅 Learn anytime. New course every week. 📬 Subscribe to The Kenakin Brief → https://www.terrykenakin.com #GPCRscience #drugdiscovery #TerrysCorner #GPCRpharmacology #ligandbinding | Dr. GPCR Ecosystem
Home → Flash News → 10 GPCR pharmacology lessons. Zero fluff. TerrysCorner #GPCRpharmacology #ligandbinding Published on June 30, 2025 Category Terry's Corner 10 GPCR
- Interrogating Multiscale Receptors Functions in Space
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to These receptors belong to the super-family of G-protein coupled receptors (GPCR), the major molecular GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
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