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Search results for "Esther Martinborough"
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- Choosing the Right GPCR Calcium Assay Readout for Measuring Receptor Activation
This allows researchers to perform either fluorescent or luminescent calcium measurements depending on
- Targeting Intracellular Allosteric Sites in GPCRs
/inverse agonism, where the allosteric modulator can perturb receptor signaling in a manner that is either
- Odorant receptors – a bit of smell for drug discovery
The development of antibodies directed towards an OR could either drive receptor inactivation or activation
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
chemokine receptors (ACKRs) which do not couple to G proteins and behave as scavenging “decoys” in order to either
- Glyco-sulfo hotspots in the chemokine receptor system
Chemokine receptors have either reported or predicted sites of N-acetyl galactosamine (GalNAc)-type O-glycosylation
- Fluorescence based HTS compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
Several fluorescence ligands that performed well in either FA or live-cell assays have been confirmed
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