Moro, that he truly saw how molecules could go beyond the bench and interact with biology in powerful The Moment Chemistry Met Biology Nicoli’s turning point came when he realized that molecules weren’t docking, dynamics, and ligand design—especially for receptors previously “invisible” to structural biology Molecular Dynamics Matters For Nicoli, molecular dynamics is more than simulation—it’s how we watch biology Alessandro Nicoli on the web Leibniz Institute for Food Systems Biology at the Technical University of

validation, thrombosis pharmacology, and metabolic disease biology, with contributions to multiple clinical drug discovery is grounded in classical physiology and driven by a willingness to enter fields - bone biology His belief in the biology has not changed. professional cost that nobody warns you about Moving between neuroscience, reproductive endocrinology, bone biology GPCR Podcast? Leave a Review.

Chemical biologist Johannes Broichhagen reveals how fluorescent probes transform GPCR imaging, internalization GPCR Podcast, chemical biologist Dr. Why this matters How a chemist with zero biology training became a leader in GPCR probe design. Who should listen If you’ve ever: Navigated a project where the biology refused to match the textbook to probe complex biology.

She received her BSc in Human Biology from King’s College London in 1997, and while her Ph.D. commenced Her research focuses on understanding the fundamental cell biological mechanisms regulating GPCR activity Alejandra Tomas is a molecular cell biologist and Senior Lecturer at the Department of Metabolism, Digestion GPCR Unlock the Full Dr. GPCR Podcast? Leave a Review.

skipping fragment-based screening and going directly to full bivalent IgG, the team hands functional biology He looks for target classes where existing platforms have already failed — not because the biology is GPCR Podcast , I spoke to Dr. GPCR podcast. Dr. GPCR Podcast? Leave a Review.

signaling — one of the most fundamental pathways in vertebrate development, stem cell renewal, and tumor biology Schulte is a Professor in receptor pharmacology and research group leader for the section Receptor Biology pharmacology; 2006) before starting his independent research team "Receptor Biology & Signalling" in is on Frizzled signaling and pharmacology aiming to understand the role of WNT/Frizzled signaling in biology GPCR Podcast? Leave a Review.

GPCR research community — bridging wet-lab experimentation, open-access tools, and computational biology and physical toolkit to systematically investigate GPCR-RAMP biology. biology . previously hidden layers of receptor biology . Ilana uses chemical biology-based methods to study the regulation and protein-protein interactions of

Bender uses virtual docking to find chemical probes for orphan GPCRs - receptors biology can't study GUEST Bender is a postdoctoral fellow at UCSF working at the intersection of computational structural biology He trained as a structural biologist at Vanderbilt University, working with X-ray crystallography, protein They may vary slightly from the final edited version. 00:00 Introduction 01:31 From structural biology GPCR Podcast? Leave a Review.

, sharpened in Class B receptor biology at the NIH, and refined across fifteen years of industrial drug For Hoare, the unsolved problem isn't the biology — it's the math no one wrote down. consultant 03:19 Origin story — the ATP calculation that first connected math to biology 06:16 PhD with "He basically gave me a cookie-cutter molecular biology project and worked with me at the bench directly He guided the in vitro biology efforts of the company for numerous drug discovery campaigns.

Demet Araç "Demet was an undergraduate at Bilkent University in Turkey, where she majored in Molecular Biology independent research career at the University of Chicago within the Department of Biochemistry and Molecular Biology Demet, who had studied various subjects including chemistry, physics, biology, and math, shared his interest Demet shared that his interest in science led him to study biology, genetics, and molecular biophysics through various approaches, including structural biology and signaling assays.

Sri Kosuri Sri is a biologist that has helped build technologies, labs, and companies in synthetic biology He is passionate about developing more rational ways to understand and engineer biology. , synthetic biology, and functional genomics. GPCR Ecosystem Unlock the Full Dr. GPCR Podcast? Leave a Review.

She has expertise in cell biology, pharmacology, translational medicine, oncology, immuno-oncology, immunology Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

She received her BSc in Human Biology from King’s College London in 1997, and while her Ph.D. commenced Her research focuses on understanding the fundamental cell biological mechanisms regulating GPCR activity GPCR Ecosystem Unlock the Full Dr. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

This conversation covers thermostabilization, cryoEM, and GPCR structural biology. << Back to podcast list Strategic Partner(s) Chris Tate: Thermostabilizing GPCRs for Structural Biology For most of the 1990s and early 2000s, GPCR structural biology was not a biology problem - it was a stability problem ABOUT THE GUEST Chris Tate is a group leader at the MRC Laboratory of Molecular Biology in Cambridge, structural biology The thermostabilization platform - from concept to systematic mutation screen From

This conversation explores the biology, diversity, and unexpected reach of human taste GPCRs, beginning matchmaking - applying recommendation system logic to the bitter taste receptor family Sweet taste receptor biology drug targets - asthma, cardiac physiology, and early signals in cancer biology 44:18 - Rethinking bitterness GPCR Ecosystem Unlock the Full Dr. GPCR Podcast? Leave a Review.

GPCR pharmacologist Dr. Episode Timeline 00:00 Introduction 02:15 From DNA quadruplexes to GPCR structural biology 06:32 The Fascinated by GPCRs he wrote to Dr. GPCR Ecosystem Unlock the Full Dr. GPCR Podcast? Leave a Review.

GPCR podcast. Dr. GPCR About Dr. GPCR About Dr. Monserrat Avila Zozaya I did a PhD in cell biology at CINVESTAV, Mexico. Biology and Pharmacology from Monash University. GPCR Unlock the Full Dr.

, cyclic AMP regulation, and receptor biology across tissue systems. Biology runs on opposing forces, and good pharmacology learns to see them. 07:40 Expanding the hypothesis — PAR1, PAR4, and upstream pathobiology 11:00 Gas pedals and brakes — biology's GPCR Ecosystem Unlock the Full Dr. GPCR Podcast? Leave a Review.

between modelers and experimentalists are more vital than ever How AlphaFold is shaking up structural biology—and scientists and pharmacologists Computational chemists and structural biologists Early-career researchers drug discovery Biotech leaders and R&D strategists Anyone interested in predictive modeling, AI in biology GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

A reagent gap that holds back the biology GPCR activity is targeted by one-third of all FDA-approved Part of the gap is biology. Multipass transmembrane proteins are genuinely difficult targets. GPCR x GeneTex partnership. GPCR ecosystem Dr. GPCR Dr. GPCR is a nonprofit ecosystem dedicated to advancing GPCR-targeted drug discovery.

GPCR Foundry: Accelerate GPCR Drug Discovery Move from idea to insight—faster, smarter, and with confidence GPCR University for your whole organization. Get Team Access GPCR University Expert-led courses spanning GPCR drug discovery — from receptor biology GPCR ecosystem. Let's move your GPCR discovery program forward.

Foord reflects on his path from academic neuroendocrinology to introducing molecular biology and molecular importance of team composition, negative data, and scientific community in navigating complex receptor biology Trained in neuroendocrinology, he helped bring molecular biology into traditionally pharmacology-driven The CGRP story illustrates how structural biology and pharmacology intersect with corporate decisions He argues that integrating structural biology, computational pharmacology, and genetics may still be

His team develops fluorescence-based and chemically engineered tools to study gpcr internalization and His group develops imaging and chemical biology tools to reveal how GLP-1 and GIP receptors operate within David Hodson on the Web Radcliffe Department of Medicine Islet Biology Lab University of Birmingham Unlock GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses GPCR Podcast? Leave a Review.

uveal melanoma, GαS mutations across pancreatic, colon, and appendix cancers, and chemokine receptor biology and the druggable FAK node CXCR3 and the chemokine axis that gates immunotherapy response Structural biology produced transforming efficiencies comparable to Ras, and the community largely looked away because the biology hallway conversation, combining bioinformatics from Europe, high-throughput screens from Japan, and biology checkpoint inhibitors 20:28 GαQ, uveal melanoma, and the failure of the textbook pathway 41:27 Structural biology

Tried to map signaling heterogeneity in disease-relevant models, Built assays that need to work in real biology—not Michelle Halls is an Associate Professor at Monash University and Deputy Theme Leader of Drug Discovery Biology Michelle earned her PhD in Molecular Pharmacology at Monash University, then trained in single-cell biology GPCR Premium . GPCR Podcast? Leave a Review.

GPCR University. GPCR and the offered resources in my work sphere GPCR researcher Thank you for bringing this course with About the GPCR Masterclass What is a GPCR Masterclass? The GPCR Masterclass is a live scientific discussion with a leading expert in GPCR pharmacology, receptor biology, or drug discovery.

not just sequence matches — is non-trivial, and it matters for anyone hoping to translate kidney OR biology She received her undergraduate degree in biology from Truman State University and earned her Ph.D. in laboratory of Michael Caplan at Yale University, where she studied both renal physiology and sensory biology GPCR Ecosystem Unlock the Full Dr. GPCR Podcast? Leave a Review.

Ross Cheloha approaches these questions from a chemical biology perspective - using synthetic peptide His research combines peptide chemistry, chemical biology, and nanobody engineering to build mechanistic downstream consequences for calcium homeostasis and bone biology. The biology may have been using this distinction all along: two natural ligands for the same receptor the final edited video before publishing. 00:00 Introduction 01:58 From pharmacy school to chemical biology

and Belgium, and subsequently as a cell biologist during my postdoc (2006-2011) with Dr. Marilyn Farquhar (UC, San Diego), a pioneer of modern Cell Biology. To achieve this goal, we use a wide range of established approaches (biochemistry, cell biology, genetics GPCR Unlock the Full Dr. GPCR Podcast? Leave a Review.

drug discovery is the biology, not the chemistry. << Back to podcast list Strategic Partner(s) Bryan Louis University and trained in pharmacology at NIH and in molecular biology and psychiatry at Stanford It reframes the field's task from finding good targets to understanding the biology well enough to connect Louis University in 1983, he subsequently trained in pharmacology (NIH), molecular biology, and psychiatry GPCR Podcast? Leave a Review.