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GPCR Ecosystem. List your services and your brand on the world's first GPCR CRO Bank. The GPCR CRO Bank is a marketing-first offering designed to help service providers and tool companies GPCR is the world's largest nonprofit community focused on GPCRs. As a CRO partner, you'll gain trusted access to an engaged audience of biotech teams and drug discovery GPCR?

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As a young researcher fascinated by chemokine receptors, molecular pharmacology, drug discovery, and adhesion GPCRs. GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors (GPCRs), that control virtually everything in the body, as drug targets. GPCR is to accelerate GPCR drug discovery by sharing the latest research and technology advances in the

Can models predict drug outcomes? Jens Carlsson shares how GPCR modeling is moving from explanation to real prediction in drug discovery With a deep focus on structure-based drug design, Jens discusses how his lab bridges simulation and experiment—and Outside academia, he advises companies through a consulting arm focused on ligand design strategy. GPCR Podcast? Leave a Review.

with numerous pharma and biotechs in understanding and applying in vitro pharmacology data to advance drug He specializes in kinetic analysis of drug action and is known for applying binding kinetics to the development He guided the in vitro biology efforts of the company for numerous drug discovery campaigns. of GPCR function to better target receptors. GPCR Member ResearchGate Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

as a potential drug target due to its high expression in triple negative breast cancer. GPCR Targeted Drugs and Gene Regulation in Cancer Cells Mike presented research on the effect of GPCR-targeted GPCRs and Cancer Immune Modulation Yamina and Mike had a discussion about their research on GPCRs, specifically Mike expressed a need for better tools to study GPCR localization in tissues. GPCR Podcast? Leave a Review.

He currently leads a team that provides a mechanistic understanding of small molecule drug candidates Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular , biochemical, cellular, and in vivo assessment of drug candidates in many different physiological systems He continues to pioneer in drug discovery studying GPCRs and other target classes. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

He currently leads a team that provides a mechanistic understanding of small molecule drug candidates Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular , biochemical, cellular, and in vivo assessment of drug candidates in many different physiological systems He continues to pioneer in drug discovery studying GPCRs and other target classes. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

Explore GPCR lipid rafts, bitter taste receptor pharmacology, and data integration in this expert interview For more on advanced topics in GPCR drug discovery and methods, browse additional episodes at Dr. GPCR Premium. Why the localization of Gα subunits impacts antidepressant drug efficacy and diagnostic innovation What GPCR Podcast? Leave a Review.

schedule Illuminating Functional Selectivity and Allosterism at GPCRs. receptors involved in many, if not all, physiological responses, with the ultimate goal of improving drug in-cellulo measurement of protein-protein interactions, receptor trafficking and signalling, useful for drug GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by

During his Ph.D. with David Gloriam at the Department of Drug Design and Pharmacology in Copenhagen, of Molecular Biology in Cambridge, UK, where he was working on the impact of genetic variations on drug Award” for his work on GPCRs. Dr. Alexander S. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

Juan José Fung is a Principal Scientist at GPCR Therapeutics, Inc , a drug discovery company focused Brian Kobilka , studying the dimerization of GPCRs. Dr. spent significant time in the industry studying membrane proteins, antibodies, and HTS methods for drug Juan José Fung on the web LinkedIn GPCR Therapeutics Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

engaged in researching molecular mechanisms that govern human (patho-)physiology and their interplay with drugs I aim to discover new therapeutic approaches, and druggable molecules or refine canonical drug targets to create drugs with fewer adverse effects. PhD studies in Martin Lohse lab at the Max Delbrueck Center in Berlin, I consolidated my knowledge of GPCRs GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.

into the structure, dynamics, and function of important classes of membrane proteins and prominent drug targets, including G protein-coupled receptors (GPCRs), transporters, channels, and 3 integrins. To this end, her lab uses several computational structural biology tools and rational drug design approaches GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

Sokhom Pin shares how he built a biotech career around GPCRs, designed a custom PhD path, and led teams Falling in Love with GPCRs GPCR pharmacology captured his scientific curiosity. Designing a Non-Traditional PhD While working full-time, Sokhom architected a one-of-a-kind PhD program About Sokhom Pin Sokhom Pin is a receptor pharmacologist with over 20 years of drug discovery research He is passionate about mechanistic profiling of therapeutic molecules as well as drug discovery in general

Michelle Halls shares how dissecting the spatial organization of GPCR signaling opens new doors in drug the Guest Michelle Halls is an Associate Professor at Monash University and Deputy Theme Leader of Drug How GPCR Collaboration Built an Innovation Engine 🎓 Want more like this? GPCR Premium . GPCR Podcast? Leave a Review.

<< Back to podcast list Strategic Partner(s) The Role of Quantitative Sciences in GPCRs with Dr. She has advanced the use of computational methods to meet the challenges of designing therapeutics with molecular dynamics simulation methods with emphasis on application to G-protein coupled receptors and drug design." GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.

Now at the University of Glasgow, his primary research interests are focused on the rational design of novel drugs to treat the three global health challenges of dementia, asthma, and malaria. staff supported by basic research grants investigating aspects of disease biology and the action of drugs at the University of Glasgow underpinned by a £118M new build that will house over 550 researchers designed GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program GPCR Community Presentation Breaking Barriers: My Journey from Mexico to the Heart of the Dr. GPCR Ecosystem and beyond About Monserrat Avila Zozaya "My doctoral research was focused on investigating My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR < Previous Session Next Session >

Dr GPCR is a 501(c)(3) non-profit. global GPCR community better — by upgrading the Dr GPCR University, creating more learning opportunities to make cutting-edge GPCR knowledge accessible to everyone Dr GPCR Retreat: offering free or affordable Together, we can accelerate GPCR discoveries and develop more effective drugs for everyone. 👉 Donate Now to Support the Dr GPCR Ecosystem

Accelerated Program Progression: Design robust assay cascades and establish key go/no-go points to speed Accelerated Preclinical Progression I streamline critical operational processes, from advanced assay design drug discovery. Berchiche, and I understand the intricate challenges of GPCR drug discovery. drug discovery.

Ray Stevens in 2013 solving several GPCR crystal structures, including that of the first serotonin receptor and in vitro drug discovery. Icahn School of Medicine at Mount Sinai in NYC, where I have been working on structure-function and drug discovery of GPCRs and transporters. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program signaling pathway of the ADGRA homolog Remoulade in Drosophila Beatriz Blanco Redondo The Adhesion GPCR The mammalian Remo homolog ADGRA2/Gpr124 cooperates with other GPCRs of the Frizzled family, and the Langenhan where I am studying and characterizing newly generated adhesion GPCR receptors in Drosophila Anaesthesiology and Intensive Care, Medical Faculty, Leipzig University, Leipzig, Germany 5 Institute for Drug

These receptors belong to the super-family of G-protein coupled receptors (GPCR), the major molecular target for drug development. and drug development technology. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

GPCR Affiliate Program and earn commissions by helping connect the global GPCR community. Share our ecosystem, courses, and events to advance drug discovery together. Dr. GPCR community. The Ecosystem is designed for all GPCR professionals to have an affordable and highly effective way to GPCR Ecosystem?

GPCR podcast , your host and founder, Dr. Yamina Berchiche introduces the very first podcast dedicated to GPCRs researcher and their work. GPCR Ecosystem, with the goal is to bring together GPCR scientists, biotech, and pharma leaders as well , grow, and thrive together to accelerate GPCR drug discovery and improve human health. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

<< Back to podcast list Strategic Partner(s) GPCR location matters with Dr. In my PhD, I studied the nanoscale spatial organization of G protein-coupled receptors (GPCRs) at the revealed heterogeneous spatial patterns of receptor density and activation, that are modulated in a drug-dependent These findings identify nanoscale GPCR spatial organization as an integral element of their activity GPCR Podcast? Leave a Review.

the guidance of Professor Shaun Coughlin where she worked on the newly discovered protease-activated GPCRs PARs are GPCRs that are activated through an atypical irreversible proteolytic mechanism. biology and for the identification of drug targets and future drug development. which has important functions in hemostasis, thrombosis, inflammation, and cancer and is an important drug GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

drug discovery . circuits — insights that inform next-generation functional assay development and translational therapeutic design Why this matters How receptor distribution in islets and brain circuits shapes incretin hormone drug collaborative chemistry enabled in designing receptor-targeted fluorescent ligands The moment when structural GPCR Podcast? Leave a Review.

Eleonora Comeo About this episode Eleonora Comeo is a doctoral candidate in Medicinal Chemistry and Drug We sat down to chat about GPCRs, synthesizing labeled ligands, and her unique position that allows her to work with GPCR scientists on 2 continents. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks