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exactly what Terry’s Corner delivers this week: high-impact insight into GPCR allostery, crafted for pharmacologists Career opportunities:  Exclusive pharma and academic listings you won’t find on job boards—curated for Exploit probe dependence to shape precision pharmacology.  Want to avoid off-target effects? If you work on GPCRs across translational pharmacology, drug development, or molecular pharmacology, GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who

Kenakin’s latest lecture delivers a wake-up call for pharmacologists interpreting allosteric binding Function: Two Different Worlds One of the most common—and dangerous—mistakes in allosteric pharmacology When a PAM increases radioligand binding but suppresses functional response, it’s not broken pharmacology—it The takeaway:  what looks like pharmacology failure may be a systems problem . Terry Kenakin An always-growing library of on-demand pharmacology insights The ability to vote on or

How do competing ligands slow or alter binding rates, and what does this tell you about real-world pharmacology candidates faster Unlock “Drug Binding Kinetics” Now Only in Terry’s Corner   ______ #DrugDiscovery #Pharmacology #DrugKinetics #PipelineEfficiency #PharmaInnovation #GPCR #BindingKinetics #MedicinalChemistry #LeadOptimization

Career opportunities:  Principal Scientist - In Vitro Pharmacology; Senior Scientist, Molecular Pharmacology Weekly News : jobs, events, papers, industry updates Exclusive discounts on Terry’s Corner  digital pharmacology access to insights from major conferences, emerging research, and expert commentary Whether you’re a pharmacologist GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who Edition here ➤    Access all the news and upcoming events Hashtags: #GPCR #DrGPCR #BindingAffinity #Pharmacology

Rethinking Affinity, A Critical Edge for Drug Hunters One of the most persistent misconceptions in pharmacology Katerina Leftheris : New technologies overcoming peptide limitations with insights from both pharma and At Alkermes, Sokhom Pin built an in vitro pharmacology group from scratch—not just a lab, but a culture Scientists, drug discovery teams, and pharmacologists who need curated, career-relevant updates. Access this week’s full Premium Edition here ➤ Hashtags: #GPCR #DrGPCR #BindingAffinity #Pharmacology

Every R&D team is under the same pressure: deliver validated targets, clean pharmacology, and translatable Allosteric Interactions Still Matter Orthosteric and allosteric interactions have been in pharmacology learn why this distinction is not just theory, but a practical framework to design cleaner, smarter pharmacology Equip your team with this literacy now to design cleaner pharmacology and accelerate smarter, safer programs topic suggestions 🆕 Weekly new releases to stay ahead of the science 🧠 Content built for biotech, pharma

Tomas , Kyle Sloop , et al. for their outstanding study on Class B1 GPCRs: insights into multireceptor pharmacology ’s dive into the   Classified GPCR News from October 28th to November 3rd, 2024 Industry News Nxera Pharma Third Quarter and First Nine Months of 2024 Nasdaq debutante Septerna swells its IPO to $331m Nxera Pharma Drug Discovery NEW March 12 - 14, 2025 | NextGen Biomed 2025 NEW March 25 - 28, 2025 | 10th German Pharm-Tox Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group

October 2022 Network pharmacological investigation into the mechanism of Kaixinsan powder for the treatment The network pharmacology method was used to constructe the "herb-component-target" network, and elucidated

Each week we highlight the decisions that move GPCR projects forward—from pharmacology essentials to topic suggestions 🆕 Weekly new releases to stay ahead of the science 🧠 Content built for biotech, pharma Years of chemistry, photophysics, and pharmacology condensed into one breakthrough: pHSense , a reagent They translated a fundamental principle of chemistry into a usable platform for pharmacology—showing GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

This study demonstrated the pharmacological properties and functions of PxOctβ3 in P. xylostella, thus

But Sokhom Pin stayed loyal to GPCRs , even when big pharma turned its gaze to other targets like kinases refining assays, exploring signaling bias, and building a robust knowledge base in one of the most pharmacologically

Whether supporting CROs, academic labs, or pharma teams, Celtarys engages deeply with collaborators to

Previous pharmacophore modeling studies of the β3 -AR did not involve experimental in vitro validation Ligand-based pharmacophore modeling was performed since no 3D structure of human β3 -AR is yet available A dataset consisting of β3 -AR agonists was prepared to build and validate the pharmacophore models.

Our mission is simple: bridge science and industry  by connecting researchers, biotech, CROs, and pharma Since 2007, NIS   has been a trailblazing CRO making cryo-electron microscopy (cryo-EM) accessible to pharma

April 2022 Design Pharmaceuticals Closes $5 Million Pre-series A Round to Accelerate Commercialization --Design Pharmaceuticals, a company redesigning small molecule drug discovery, today announced the closing Design Pharmaceuticals’ platform is based on ultrahigh-throughput technologies that biomine drug-like

April 2022 "SAN DIEGO, April 12, 2022 — Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX), a clinical-stage pharmaceutical company focused on the discovery, development and commercialization

April 2022 Applying Allosteric Modulator Pharmacology to Treat Dyskinesia and Other Movement Disorders Addex Therapeutics "Tim Dyer is the Co-Founder and CEO of Addex Therapeutics, which is focusing on the pharmacology

March 2022 Crinetics Pharmaceuticals Expands Executive Team With Appointment Of James Hassard As Chief Commercial Officer "SAN DIEGO – March 1, 2022 – Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization

Terry's Corner - New Course on Pharmacologic Models The latest Terry’s Corner unlocks clinical forecasting in the full newsletter   Secure Your Access Now ➤ 🗣️ “Thank you for bringing this (Principles of Pharmacology

Highlights: Congratulations to our amazing Board Member JoAnn Trejo for being elected to the British Pharmacological News from December 2nd to 8th, 2024 Industry News 2024 Fellows and Honorary Fellows announced Nxera Pharma to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox GPCR Jobs GPCR Molecular Pharmacologist Scientist - Biology Scientist I Cell Biology - Tectonic Therapeutic Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group

Welcome Back, Discovery Drivers   Terry’s Corner is live, on-demand pharmacology built for drug discovery Dr.GPCR Updates Terry’s Corner is Live - Pharmacology at your fingertips Terry’s Corner is now open! Better pharmacology leads to better decisions—unlock it now with Terry’s Corner.

Terry Kenakin takes you on a captivating tour through the history of pharmacology : a journey that spans Whether you're stepping into pharmacology for the first time or rekindling your interest, this lesson Terry’s Corner, your essential launchpad into the world of therapeutic science Unlock "The History of Pharmacology

In the newest foundational lesson from Terry Kenakin’s Pharmacology Vault , we unlock the visual language of pharmacology: dose-response curves . 👉 Discover why dose-response curves are the backbone of all pharmacology.

Welcome to Terry’s Corner , where foundational pharmacology is demystified by someone who’s spent over In his newest lesson, “The Uniqueness of Pharmacology in Drug Discovery,” Terry Kenakin explains why pharmacology isn’t a clean-cut science—it’s a dynamic dialogue between molecule and system. You’ll uncover: Why pharmacology is the glue between chemistry and biology How to interpret drug behavior the story it’s telling. 👉 Start your journey with Terry’s foundational series Unlock "Unique Role of Pharmacology

Did you know that each month we collect the most recent #GPCR publications and the newest Biotech/Pharma

December 2021 Crinetics Pharmaceuticals announced the formation of an independently operated new company and Crinetics to Collaborate on Multiple Additional targets SAN DIEGO, October 18, 2021 — Crinetics Pharmaceuticals (Nasdaq: CRNX), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization

We’ve made some updates to the Principles of Pharmacology I & II courses, and we can’t wait for you Here’s the refreshed schedule: Principles of Pharmacology I October 3, 10, 17, 24 Principles of Pharmacology Don’t miss out on insightful resources like '   Applying Pharmacology to Drug Discovery ' and ' Advanced Data Analysis for GPCR Pharmacology .' Don’t miss your chance to dive into the Principles of Pharmacology I & II BUNDLE .

Richard is the architect behind nearly all of Exscientia's partnerships and collaborations across pharma

As Chief Matchmaker, I recently had the pleasure of speaking with Beth Fleck, Director of In Vitro Pharmacology at Crinetics Pharmaceuticals.  Beth is also the hiring manager for their open Principal Scientist, In Vitro Pharmacology role posted Top candidates will have a solid foundation in GPCR pharmacology as well as some experience in drug discovery

This Week’s Highlights: G protein-coupled receptor (GPCR) pharmacogenomics Miles D Thompson , David Jonasson, CFO & CBO at Absci Octant: A Next Generation Approach to Genetic Disease Antiverse, Nxera Pharma to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox GPCR Jobs NEW GPCR Molecular Pharmacologist Scientist - Biology Scientist I Cell Biology - Tectonic Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group