Search Results
Results found for "Dongbo Bu"
- Innovative Data-Driven Solutions: The pHSense Revolution
of scaffold families Key milestone: Clean signal in endogenous beta cells Revvity commercial launch Building Build or adopt assays that can evolve with your questions—like pHSense.” What’s Next? GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research or career. 👥 Build
- Transformative GPCR Insights: Unleash New Horizons in Science | Sep 9 - 15, 2024
Burger , Arthur Christopoulos , David M. 🚨 Hurry to reserve your spot for the Principles of Pharmacology I & II BUNDLE before the Early
- Beyond Clearance: The Strategic Power of Irreversible Drug Binding
Irreversible binding isn’t a magic bullet. It’s a double-edged sword. Terry’s Corner and get: Frameworks proven in real discovery programs On-demand lessons designed for busy That’s why discovery teams turn to Terry’s Corner: to build strategies that anticipate these collisions If you’re not designing with persistent enzyme interactions in mind, you’re building risk into your molecule
- How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs
If you’re building tools or careers in GPCR science, this is your playbook. Eric Trinquet Built to Fail, Built to Win: Inside the IP1 Assay Origin Story The IP-One assay didn’t The pHSense Breakthrough: Two Dimensions of Discovery pHSense wasn’t built in a vacuum—it was born from From Theory to Tool: How Great Products Get Built pHSense didn’t materialize overnight. Build theories, but be ready to toss them.
- Understanding Enzyme Inhibition In GPCR Discovery Programs
Your Membership Gives You: Proven frameworks used in real discovery programs On-demand lessons built for busy scientists A voice in future course topics Fresh, weekly content that stays relevant Live monthly Whether you’re building assays or a scientific career, this is a must-read on why risk, surprise, and It’s built for scientists and teams who want fewer tabs and faster decisions—one scroll that blends structure
- Enzyme Inhibition Pharmacology: The Hidden Gatekeepers of GPCR Drug Discovery
twice—first by its receptor, then by its enzymes.Ignoring the second gatekeeper means wasting cycles, budgets Your Membership Includes: Frameworks proven in real discovery programs On-demand lessons designed for busy
- Assay Volume Control: Your GPCR Drug Discovery Power Lever
gives you: Proven frameworks for real-world GPCR drug discovery Flexible , on-demand lessons for busy the curriculum with your topic suggestions Weekly new releases to stay ahead of the science Content built It’s built to compress your time to clarity—so you can pick better targets, stress-test hypotheses earlier Acting on the right signals today prevents tomorrow’s delays—and puts you ahead when budgets and timelines
- The Truth About GPCR Product Launches: Years in the Making
Built to Fail, Built to Win: The IP One Gamble After the success of their cAMP assay, Trinquet’s team The goal wasn’t to build a pH sensor—it was to create brighter, more stable lanthanide complexes for It’s when the tools you built in-house meet the problems no one saw coming. pHSense isn’t just a probe GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research or career. 👥 Build
- Assay Sensitivity: The Hidden Lever Driving GPCR Drug Discovery
Why Members Join: Frameworks proven in discovery programs On-demand lessons built for busy scientists
- Orthosteric vs Allosteric Interactions— and the pHSense Shift in Internalization
membership gives you: 📚 Proven frameworks for real-world discovery 🌍 Flexible, on-demand lessons for busy curriculum with your topic suggestions 🆕 Weekly new releases to stay ahead of the science 🧠 Content built
- Orthosteric vs. Allosteric Interactions: The Silent Decider of Safety and Success
But here’s the truth: too many programs still fail because early decisions were built on shaky mechanistic For teams building structure–activity relationships (SAR), this insight is gold: you’re not just chasing membership gives you: 📚 Proven frameworks for real-world discovery 🌍 Flexible, on-demand lessons for busy curriculum with your topic suggestions 🆕 Weekly new releases to stay ahead of the science 🧠 Content built
- How to Design GPCR Drugs That Work in Vivo: Strategy, Tools, and Insights
Breakthroughs this week: Lilly to build $5B manufacturing facility in Virginia; Novo Nordisk flags drug GPCR Podcast, the Revvity team built pHSense™ from the ground up by listening to what GPCR scientists
- Why Opposing Processes Matter for Your Next GPCR Drug
If your job is to move molecules confidently toward the clinic, this is a blueprint for building a more
- Dr. GPCR Spotlights Revvity’s pHSense™ Internalization Tools
A GPCR Internalization Tool Designed for Real Research Needs Built on more than two decade A GPCR Internalization
- How Advanced GPCR Kinetics Sharpen Decision Making (and Save You Time)
It’s built for the GPCR community—by people who live the science—so you spend less time sifting and more
- GPCR Drug Discovery at Discovery on Target: Why This Track Is About More Than Receptors
Over the years, we’ve built a global network of researchers, biotech leaders, and pharma innovators who
- The Five Traps of Ignoring Kinetics
It’s the difference between building a solid pipeline and chasing ghosts.
- Mechanism vs. Assumption: A Model-First Path to Getting GPCR MoA Right
It’s built for scientists and leaders who want the signal, not the scroll: frameworks that clarify mechanism
- From Snapshots to Predictions: Why Mechanism of Action Matters
But you can build confidence through iteration. It’s learning how to design, interpret, and decide with models built in . Built for discovery-phase teams, pharmacologists refining fundamentals, scientists challenging legacy
- How a Failed Med School Dream Sparked a GPCR Biotech Revolution
Blue Therapeutics: Turning GPCR Biology Into a Business Ajay’s academic training planted the seeds for It was investor rejections, endless slide decks, and the steep learning curve of biotech business. narratives, navigating startup fundraising, and building an operational team. Superluminal is building systems that learn from receptor movement, conformational shifts, and complex By staying grounded in scientific rigor while embracing the tools of business and technology, he’s built
- GPCR Happy Hour – Boston, Sept 2025
GPCR is a nonprofit global community dedicated to building a strong, connected GPCR ecosystem. be part of the conversations that will ripple far beyond Boston. ✨ GPCR Happy Hour: Where science, business
- Curve Shifts Don’t Lie, But Your Eyes Might
By the end, you’ll know how to choose the right test, design experiments with power built in, and validate It’s learning how to design, analyze, and decide with confidence built in.
- Understanding the Journey: Catherine Demery's Path to Addiction Science
It was here that the disciplined structure of industry science helped her re-find purpose and build confidence alcoholism and opioid addiction—a decision that would reshape her academic ambitions. “...I had a light bulb Industry can build skills that academia often overlooks.
- Purpose-Driven Opioid Research: Catherine Demery’s Academic Path
Careers built on prestige, titles, or external pressure can burn out quickly. But careers built on urgency, alignment, and meaning are the ones that last. It was the first time late nights in the lab weren’t a burden but a sign of genuine engagement. Real-world data should guide how we build preclinical models.
- Allosteric Binding Demystified: Smarter GPCR Drug Discovery
Sharpen your discovery decisions ➤ Yamina’s Corner - The Hidden Cost of Busy A GPCR program can collapse—not Stop wasting talent: When senior leaders spend nights copy-pasting data, your burn rate accelerates
- The Hidden Driver of GPCR Drug Success: Why Target Residence Time Matters More Than You Think
for GPCR scientists and translational teams, Premium keeps you informed on the science, careers, and business
- Fentanyl and Xylazine: Why Breathing Fails in Overdose
For Catherine, those numbers aren’t just statistics—they’re signals guiding how to build better models
- Why “Displacement” Misleads You: Allosteric Binding Demystified
Terry’s Corner is built for scientists who want to move faster , think sharper , and make smarter decisions
- Maria’s Travel Blogs: ACSMEDI-EFMC Medicinal Chemistry Frontiers 2025
She has a lot of experience working for bigger businesses which she now shares as an advisor for startups






























