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Careers built on prestige, titles, or external pressure can burn out quickly. But careers built on urgency, alignment, and meaning are the ones that last. It was the first time late nights in the lab weren’t a burden but a sign of genuine engagement. Real-world data should guide how we build preclinical models.

Sharpen your discovery decisions ➤ Yamina’s Corner - The Hidden Cost of Busy A GPCR program can collapse—not Stop wasting talent:  When senior leaders spend nights copy-pasting data, your burn rate accelerates

for GPCR scientists and translational teams, Premium keeps you informed on the science, careers, and business

For Catherine, those numbers aren’t just statistics—they’re signals guiding how to build better models

Terry’s Corner is built for scientists who want to move faster , think sharper , and make smarter decisions

She has a lot of experience working for bigger businesses which she now shares as an advisor for startups

.; Burger, A.

Budded baculoviruses (BBV) have a high receptor concentration as well as being homogenous in size, which Using the FA method, CELT-419 binding affinity and kinetics were determined using budded baculovirus An equivalent volume of assay buffer was added to association controls (filled dark blue circles). Displacement of CELT-419 by different concentrations of Butaclamol  (A)  and PL-384  (B)  at different M.; Bucolo, C.; Platania, C. B. M.; Salomone, S.; Drago, F.

This isn't just another lecture series; it's a practical tool designed to help you recognize and build

They’re hired for science, not for building operational scaffolding. Every two-week delay in a DMTA cycle can burn through hundreds of thousands in salaries and overhead. Build Precision Systems for GPCR Drug Discovery The only way out for GPCR drug discovery programs isn And if your systems aren’t built for precision, you’ll run out fast. 👉 In Part 2, we’ll expose exactly Let’s build the systems now, before the next delay burns another half a million. 🚀 Book your free 30

Redefine Your Pipeline If your development program is built around potency alone, you may be leaving

As the lab grew, so did his responsibilities: from building computational models of GPCRs to guiding

Sharpen your discovery decisions ➤ Yamina's Consulting Corner - Building Your GPCR Program for Breakthroughs Solve the problem of a fragmented approach by learning how to build a unified system where every scientific Three takeaways from this week’s feature: Stop firefighting:  Learn why solving isolated problems burns Build predictable success:  Use a repeatable improvement framework to turn operational chaos into precision

Terry’s Corner  is built to help you avoid those traps. Why now:  GPCR research is accelerating—and the projects that succeed will be those built on clear, accurate

hours—not minutes—to equilibrate  ✅ A framework for designing or troubleshooting allosteric modulators with built-in Ask-Me-Anything sessions A growing, curated on-demand library Opportunities to shape future topics Built

If your pipeline is built only around extracellular engagement, you might be leaving opportunities untapped

Outdated Models Slow Your Next Program The analytical tools that shaped traditional affinity assays were built

🔹 Elevate your strategy → Building clarity in GPCR drug discovery Even the strongest GPCR programs stall—not from bad data, but from buried decisions; Yamina's Corner helps teams cut through the noise and build clarity that drives action 🔹 Innovate faster → Celtarys’s newest GPCR tools Explore new screening tools purpose-built for

: A Model for R&D Success Scientific rigor doesn’t thrive in cultures defined by micromanagement or burnout At Alkermes, Sokhom Pin built an in vitro pharmacology group from scratch—not just a lab, but a culture

Your work belongs in the core conversation—not buried in supplementary files.

Expand your computational toolkit ➤ Call for Papers: GPCRs: Signal Transduction, Volume II Building on

While fascinated by organic chemistry and the idea of “building molecules,” he didn’t see the big picture—until Within weeks, he moved to Germany and became her first PhD student—helping build a lab from the ground limited ligand data, olfactory GPCRs represent a high-risk, high-reward challenge —perfect for a PhD built

Born in California and raised in Silicon Valley, his early interests were in finance and business. Building a Career from the Inside Out Now back in med school, Serafini aims to follow the physician-scientist

The GPCR Data Dilemma: The Lego Bucket Problem I've seen promising GPCR programs generate massive volumes I call this the Lego Bucket Problem . You have the data, but not the definitive direction. GPCR, we've built a global hub connecting over 1,300 GPCR scientists dedicated to this field. My Consulting Philosophy This practice is built on three core values: Scientific Integrity:  Every Collaborative Partnership:  I embed, contribute, and build solutions hand-in-hand with your team.

I call it the Lego Bucket Problem : You’ve got CRO output, internal assay data, maybe even some promising Not possible when nothing’s built to surface the right  insights early. That’s Why I Built Yamina’s Consulting Corner This is not “advising.” challenges firsthand, identify roadblocks faster , and i mplement solutions from within , ensuring genuine buy-in Operational Discipline ✔️ Collaborative Partnership Let’s Get Your GPCR Program Moving Again Whether you’re building

While others pivoted, Sokhom went deeper: refining assays, exploring signaling bias, and building a robust A Career Built on Consistency From CGRP receptor antagonists at BMS to opioid receptor research at Alkermes

Welcome Back, Discovery Drivers   Terry’s Corner is live, on-demand pharmacology built for drug discovery That’s the Lego Bucket Problem.   

HT1A agonist, delivers selective pain relief in preclinical models Dr.GPCR Updates Terry’s Corner  – Build It’s a story of leadership, scientific rigor, and tools built for the needs of modern discovery teams CXCR4 signaling promotes terminal erythropoiesis  through nuclear translocation and perinuclear calcium bursts

importance of genuinely listening to researchers: understanding the biological question first, then building

Explore her path from postdoc to platform builder.