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structure, dynamics, and function of important classes of membrane proteins and prominent drug targets, including

novel paradigms of drug action at GPCRs, particularly allosteric modulation and biased agonism, and incorporates Professor Christopoulos has over 360 publications, including in leading international journals such as He has also been the recipient of multiple awards, including the John J. GPCR AI Summary Quick recap Yamina and Arthur discussed Arthur's career journey in pharmacology, including Arthur shared his career journey, including his collaboration with Patrick Sexton and Jim Burch, and

) and arrestins as GPCR regulators and as mediators of distinct signaling pathways through partners including In our work, we utilize methods including structural biology and proteomics, molecular biology and biochemical

Ray Stevens in 2013 solving several GPCR crystal structures, including that of the first serotonin receptor

Caron has received numerous awards including a Burroughs Wellcome Fund Career Award in the Biomedical

Slosky’s work has been recognized through several travel and research awards, including the William James Slosky is passionate about training the next generation of scientists and increasing diversity, equity , and inclusion in science.

research focuses on understanding the fundamental cell biological mechanisms regulating GPCR activity, including

Badr worked in various science labs, including Dr. Christian Badr’s and Dr.

GPCR Podcast; her earlier episode covers her scientific profile in depth, including her research trajectory whole conversation: the structural shifts forced by the shutdown — planned reflection, remote meeting inclusion

Premium Weekly News is included in Dr.

) and arrestins as GPCR regulators and as mediators of distinct signaling pathways through partners including In our work, we utilize methods including structural biology and proteomics, molecular biology and biochemical

His scientific training included a PhD at the International Center for Genetic Engineering and Biotechnology

Why this matters How receptor distribution in islets and brain circuits shapes incretin hormone drug

They worked on the interactome of yeast and mammalian Rab5 homologs including identification of Rab5 Tall has presented his work at 59 invited seminars including national and international meetings and

contributed to the identification of RAMP proteins, the GABA-B heterodimer, and ligands for orphan receptors including

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Kim describes a personal inclination toward challenging research areas. GPCR Drug Discovery Is Increasingly Structural Modern GPCR drug discovery increasingly integrates structural Showing those structures to my colleagues—and realizing that the experiment actually worked—was incredibly

GLP-1R and GIPR Imaging: From Cell Assays to In Vivo Systems Fluorescent tools for imaging endogenous incretin receptors across biological systems Interrogating Incretin Receptor Biology Across Biological Complexity localization, nanodomain organization, and functional engagement within complex biological systems remain incompletely His group focuses on the development of chemical tools — including fluorescent ligands and photopharmacological glucose homeostasis, food intake regulation, and inflammation — within complex tissue environments including

He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility

For the purposes of this presentation, I will walk you through my various career experiences and include

His current efforts bridge teaching in Toronto and ongoing research, including the development of an

also has globally-recognized expertise in bioluminescence resonance energy transfer (BRET) technology, including

He is author of over 100 papers, including several in Nature, Science and Cell.

and therefore blood pressure; another regulates glucose handling through a transporter family that includes Pluznick's advice to early-career scientists is shaped by her own near-dismissal of an inconvenient microarray

On-demand recordings are included inDr. Recipient of major honors including the ACS Smissman Award and the ASPET Goodman and Gilman Award for

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One day as they were catching up, Jacob shared his struggles of managing samples and an incredible amount

remotely; the continuity of receptor pharmacology work already in the pipeline before the shutdown, including

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