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Results found for "Inversago Pharma"

  • Exscientia welcomes Richard J. Law, as their new Chief Business Officer

    Richard is the architect behind nearly all of Exscientia's partnerships and collaborations across pharma

  • 📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024

    We’ve made some updates to the Principles of Pharmacology I & II courses, and we can’t wait for you Here’s the refreshed schedule: Principles of Pharmacology I October 3, 10, 17, 24 Principles of Pharmacology Don’t miss out on insightful resources like '   Applying Pharmacology to Drug Discovery ' and ' Advanced Data Analysis for GPCR Pharmacology .' Don’t miss your chance to dive into the Principles of Pharmacology I & II BUNDLE .

  • Job Opportunity Spotlight #1: Principal Scientist, In Vitro Pharmacology

    As Chief Matchmaker, I recently had the pleasure of speaking with Beth Fleck, Director of In Vitro Pharmacology at Crinetics Pharmaceuticals.  Beth is also the hiring manager for their open Principal Scientist, In Vitro Pharmacology role posted Top candidates will have a solid foundation in GPCR pharmacology as well as some experience in drug discovery

  • Hop in the Time Machine with GPCR: Unraveling the Future of Research! ⦿ Nov 24 - Dec 1, 2024

    This Week’s Highlights: G protein-coupled receptor (GPCR) pharmacogenomics Miles D Thompson , David Jonasson, CFO & CBO at Absci Octant: A Next Generation Approach to Genetic Disease Antiverse, Nxera Pharma to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox GPCR Jobs NEW GPCR Molecular Pharmacologist Scientist - Biology Scientist I Cell Biology - Tectonic Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group

  • Exscientia is 10 years old this July!

    treatment selection in patients with advanced haematological cancers, international partnerships with pharma

  • 📰 GPCR Weekly News, July 24 to July 30, 2023

    This week's highlights: Driving Pharma Innovation in Oncology: Domain Therapeutics' Success Proven by The Neuromedin U system: pharmacological implications for the treatment of obesity and binge eating behavior 2023 Financial Results Scientists Discover a New Way To Develop Drugs Without Side Effects Driving Pharma

  • GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!

    I We are diving into the second class of our Principles of Pharmacology I course with enthusiasm and Seize this opportunity to enhance your expertise and proficiency in pharmacology! Modules: October 31st : The Eyes to See- The Importance of Pharmacologic Assays. s dive into the   Classified GPCR News from September 30th to October 6th, 2024 Industry News Nxera Pharma experienced commercial R&D executive Makoto Sugita as Chief Medical Officer and President of Nxera Pharma

  • Enhancing GPCR Research Outreach | Dr GPCR University early-bird registration ends soon!

    and Daniel Isom  for their research on Advances in yeast synthetic biology for human GPCR biology and pharmacology Materials Access to the private group Certificate of participation Learn the essentials: Measuring the pharmacologic genetic disease Advances in yeast synthetic biology for human G protein-coupled receptor biology and pharmacology DMS: Linking Protein Structure To Function AbbVie Completes Acquisition of Cerevel Therapeutics Nxera Pharma 7, 2024 | 16th Annual PEGS Europe   July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

  • Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future

    A diverse pharmacopoeia of cannabinoid ligands is available, which has led to considerable advancements development and progress in optimising physicochemical properties, understanding advanced molecular pharmacology

  • Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and...

    October 2022 Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and Pharmacological targeting of cGAS/STING-YAP signaling by both a small-molecule STING agonist, SR-717, Further, pharmacological targeting of cGAS/STING-YAP axis exhibits the potential to alleviate liver and

  • Developing the Cannabinoid Receptor 2 (CB2) pharmacopeia: past, present, and future

    A diverse pharmacopeia of cannabinoid ligands is available, which has led to considerable advancements development and progress in optimizing physicochemical properties, understanding advanced molecular pharmacology

  • Exploring pharmacological inhibition of G q/11 as an analgesic strategy

    The aim of this study was to test this hypothesis pharmacologically by using potent and selective Gq/

  • A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology in...

    August 2022 A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology monitor the activation state of G protein-coupled receptors are a useful addition to the molecular pharmacology

  • Dopamine D 1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior...

    August 2022 Dopamine D 1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, We now summarize important pharmacological, molecular, and cellular studies relevant to D1-mediated β-arrestin-related

  • Combined docking and machine learning identify key molecular determinants of ligand pharmacological

    detailed structure‐activity relationship that identifies small changes to the ligands that invert their pharmacological

  • Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of...

    September 2022 Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of immunotherapy in triple-negative breast cancer "Quantitative systems pharmacology (QSP) modeling is an emerging mechanistic computational approach that couples drug pharmacokinetics/pharmacodynamics and

  • How System-Level GPCR Thinking Prevents Discovery Failures

    If your work touches GPCR pharmacology, these insights aren’t optional—they’re essential. Career opportunities:  Senior/Principal Scientist—GPCR Pharmacology; Principal Scientist—In Vitro Pharmacology Terry’s Corner: GPCR Pharmacology Insights That Prevent Real Drug Discovery Failures Discovery collapses Researchers, pharmacologists, biotech teams, and decision-makers who rely on accurate, efficient, interpretation-first

  • From Pipettes to Platforms: The Evolution of GPCR Research

    What started as hand-built assays on ice has become integrated platforms for drug discovery, systems pharmacology

  • How GPCR Spatial Signaling Sparked a Scientific Journey

    From Cambridge to Leadership That early curiosity led her to pursue a PhD in Molecular Pharmacology at 2011, she had established her own group within the Drug Discovery Biology theme at Monash Institute of Pharmaceutical

  • From Failed Experiments to Predictive GPCR Models

    With limited structural data but a growing pharmacological interest, GPCRs presented the perfect challenge Collaborating with chemists, biologists, and pharmacologists not only made his predictions more useful Pharmacology, on the other hand, is often outsourced through collaborations with expert labs who specialize Carlsson notes that it’s easier to find pharmacologists to run assays than it is to persuade chemists Trainees must learn how to interpret assay data, understand pharmacological context, and communicate

  • New Tools, Smart Signals, and The Kenakin Brief

    Early Access and Updates    Terry’s Corner is launching soon with monthly courses, AMAs, and real-world pharmacology

  • The Truth About GPCR Product Launches: Years in the Making

    GPCR internalization isn’t just a trafficking readout—it’s pharmacology. s partnership with Durham (chemistry) and the Institute of Functional Genomics in Montpellier (GPCR pharmacology

  • Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024

    Allosteric GPCR Binding Sites and Their Ligandability Potential Today, we started the Principles of Pharmacology News UNC School of Medicine to Receive $3-Million Award from ARPA-H’s Sprint for Women’s Health Nxera Pharma Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and I Cell Biology - Tectonic Therapeutic PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group

  • Why Opposing Processes Matter for Your Next GPCR Drug

    β-receptor partial agonists, showing how heart rate set-points under different anesthetics can flip observed pharmacology Subscribe today and get direct access to decades of pharmacology experience that turn complex systems Why Terry’s Corner Most pharmacology training freezes at equilibrium snapshots.

  • The Five Traps of Ignoring Kinetics

    That’s not pharmacology. That’s kinetics. It’s a shift in how expert drug hunters see pharmacology. Unlock “Kinetics: Advanced Applications” Only in Terry’s Corner Why Terry’s Corner Most pharmacology engagement opportunities  through AMAs and topic suggestions Practical insights  distilled from decades of pharmacology

  • Curve Shifts Don’t Lie, But Your Eyes Might

    When Curves Shift Some of the most difficult calls in pharmacology happen when two curves look  slightly Is it a real pharmacological effect, or just noise? Here’s where the F-test  becomes indispensable. engagement opportunities  through AMAs and topic suggestions Practical insights  distilled from decades of pharmacology curvecomparison #ftest #assayvalidation #experimentaldesignstatistics #assayreproducibility #ANCOVA #pharmacology

  • Understanding the Journey: Catherine Demery's Path to Addiction Science

    She entered undergrad set on becoming a pharmacist. After excelling in the PCAT and gaining admission to pharmacy school at the University of Michigan, it kind of had an identity crisis because I think I realized in that moment that I didn't want to be a pharmacist It’s rigorous pharmacology, but deeply tied to urgent public health needs. Catherine's decision to defer pharmacy school was a leap of faith that opened new doors.

  • Purpose-Driven Opioid Research: Catherine Demery’s Academic Path

    The turning point came during her master’s program in pharmacogenomics. Rather than treating opioid pharmacology as a purely theoretical exercise, she collaborates with harm-reduction This approach makes her models not just rigorous, but translational—bridging the gap between receptor pharmacology That personal loss transforms complex receptor pharmacology into something immediate and human. And GPCR pharmacology isn’t just an academic pursuit—it’s essential to understanding and responding to

  • Fentanyl and Xylazine: Why Breathing Fails in Overdose

    First responders describe revivals that don’t feel like revivals, as if the body is still trapped in a pharmacological

  • Differential binding of Δ9-tetrahydrocannabinol derivatives to type 1 cannabinoid receptors (CB1)

    This interest has been driving efforts to understand their pharmacology since the 1980s. CELT-335 was successfully used in assays to determine the pharmacological properties of Δ9-tetrahydrocannabinol binding of naturally occurring Δ9-tetrahydrocannabinolderivatives to cannabinoid CB1 and CB2 receptors, Pharmacological Zagzoog A et al ., In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPARγ and CB1 receptors, British Journal of Pharmacology

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