Search Results

Saraf " My research focuses on evaluating and targeting serotonin 1A receptors for therapeutic outcomes

biosensors, cryo-EM, photoswitchable ligands, and nanobodies as pharmacological tools and potential therapeutic

Terry Kenakin’s unique course, Development of GPCR Ligands as Therapeutic Drugs , and gain essential signaling and drug discovery Symposium & Workshop - Brazil NEW April 1 - 3, 2025 | 2nd Peptide-Based Therapeutics Summit - USA April 2 - 3, 2025 | New therapeutic modalities: Transforming receptor pharmacology - UK Australia GPCR Jobs NEW Open Postdoctoral position - Stanford University Structural Biologist - Confo Therapeutics Pharmacologist - Schrödinger Scientist - Biology - Superluminal Medicines Scientist I Cell Biology - Tectonic Therapeutic

She has advanced the use of computational methods to meet the challenges of designing therapeutics with

orphan GPCRs from ‘locked’, inaccessible receptors to well-characterized and understood ‘unlocked’ therapeutic

The ultimate goal of Adriano’s research is to target novel aspects of GPCR signaling for therapeutic

Award and the Goodman and Gilman Award from the American Society for Pharmacology and Experimental Therapeutics Institute, highlighting its translational approach to research and its capacity to translate research into therapeutic

Award and the Goodman and Gilman Award from the American Society for Pharmacology and Experimental Therapeutics Institute, highlighting its translational approach to research and its capacity to translate research into therapeutic

Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994).

Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994).

nanobodies as research tools, to investigate different GPCR conformations, while also focusing on their therapeutic

GPR56 as a mechanical sensor and his sustained case for the KLF2 signaling pathway as a GPCR-linked therapeutic His recently published book on signaling bias, Biased Signaling in Physiology, Pharmacology, and Therapeutics

Themes of the Conversation Allosteric modulation of opioid receptors - mechanism, selectivity, and therapeutic The therapeutic logic is that decoupling from the orthosteric site might preserve pain relief while altering

GPCR field, and serves as Deputy Director of the Australian Research Council Centre for Personalised Therapeutics Institute of Medical Research, Deputy Director of the Australian Research Council Centre for Personalised Therapeutics

Current lines of work include isoform-selective HSP90 inhibition as a strategy for widening the opioid therapeutic This is not a quirk — it is the central clue the lab has built a therapeutic strategy around.

. 🗓️ Upcoming 4-Week Course: Development of GPCR Ligands as Therapeutic Drugs starting March 20 – April biotechs public Aikium's AI-Driven mRNA Engine Looks to Address Undruggable Disordered Proteins Tectonic Therapeutic - 21, 2025 | 2nd GPCR signaling and drug discovery Symposium & Workshop NEW April 2 - 3, 2025 | New therapeutic PhD Position GPCR Molecular Pharmacologist Scientist - Biology Scientist I Cell Biology - Tectonic Therapeutic

receptors would be a significant breakthrough in cardiovascular biology as they could be targeted for therapeutic

list Strategic Partner(s) Inês Pinheiro, Monserrat Avila Zozaya & Yamina Berchiche About Inês Pinheiro PharmD

neuronal circuits — insights that inform next-generation functional assay development and translational therapeutic

modulate drug seeking, habit formation, and reward processing - and has been pursued as a potential therapeutic adolescent alcohol exposure disrupts mGlu2 function in the striatum in a way that might seem to close off therapeutic

He argues for a therapeutic strategy built around modulators that can be combined, rather than single His recently published book on signaling bias, Biased Signaling in Physiology, Pharmacology, and Therapeutics

mutations in the GABA-B transmembrane domain and what they suggest about precision pharmacology The therapeutic But its therapeutic window is narrow.

Randy has received a number of research prizes, including the PhRMA New Investigator Award, the Distinguished

By integrating advanced tools and translational biology, his work directly informs therapeutic strategies

Sep 20, 2022 — First contributor article published: Therapeutic validation of an orphan G protein‐coupled

Inês Pinheiro PharmD by training and Ph.D. candidate in Hartley's lab at the University of Geneva.

Unconventional GPCR Ligands <p class="font_8">Watch Now</p> Terry Kenakin The New Frontier of GPCR Therapeutics

Each session explores mechanistic models, translational challenges, and real-world therapeutic implications

Clements' work is primarily focused on translational developments of small molecule therapeutics, and

structural biology and drug discovery, where molecular structures inform the design and development of new therapeutics You could easily imagine separate therapeutic programs targeting those different physiological effects