Breaking the Mold Most scientists follow the usual script—graduate school, lab rotations, dissertation engineered a third path : a partnership between BMS and UConn that allowed him to do industry-based research How It Worked BMS funded the research, salary, and even tuition UConn accepted the research done in the BMS lab as part of the dissertation Sokhom met weekly with advisors and monthly for presentations All research

Exploring the Hidden Dynamics: How Kinetics Reveals What Equilibrium Conceals in GPCR Research. members get to rewatch the recording Subscribe to the Kenakin Brief and Join the Live AMA ➤ Celtarys Research Fluorescent small-molecule ligands flip the script: direct binding to functional sites, live-cell compatibility master GPCR science — in one membership. 🎓 Full GPCR University + 🔬 200+ expert talks 🗞️ Weekly research networking, AMAs & matchmaking 💡 Support open resources for the global GPCR field 🧠 Designed for researchers

GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced "We look forward to sharing our science, our services, and our team's expertise with researchers advancing drug discovery by pairing comprehensive, end-to-end services with an engaged global community of GPCR researchers assays, and one of the broadest ranges of GPCR targets in the industry, Eurofins Discovery supports researchers

GPCR , the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced This partnership is designed to support the GPCR research community by expanding access to validated, assays—they build true scientific partnerships that help teams get the most from their data and advance GPCR research we look forward to sharing scientific insight, best practices, and real-world applications that help researchers cell-based assay technologies, providing industry-standard, regulatory-accepted platforms spanning basic research

Their method allows researchers to explore different linker positions, tailor activity (agonist or antagonist Maria emphasizes the importance of genuinely listening to researchers: understanding the biological question GPCR ecosystem , Celtarys is opening up that model to the broader research community. The goal? ______________ Keyword Cloud:   GPCR data platform , fluorescent ligands , assay development , GPCR research

co-founders soon realized, commercializing it was the only way to deliver that value to the broader GPCR research Celtarys Research, now partnering with Dr. GPCR, is helping researchers worldwide gain access to customized, reliable assay tools without the delays science-driven solutions on their company page . _______________ Keyword Cloud:   GPCR drug discovery , GPCR research

opportunities:  Senior/Principal Scientist—GPCR Pharmacology; Principal Scientist—In Vitro Pharmacology; Research Johannes Broichhagen Reliable imaging tools change how researchers see receptor behavior. This feature from Celtarys Research outlines how to structure an HCS workflow that avoids batch effects It’s a system-aware resource built for researchers who need clarity fast—reinforcing system-level GPCR Weekly research, careers, and industry intelligence; GPCR University; 200+ expert talks; networking;

In research, including the GPCR world collaboration isn’t a luxury. It’s survival. The GPCR Collaboration Mindset Behind Breakthrough Science Most researchers have a story about the moment And some simply misled entire research programs. The result was a set of chemical probes that finally allowed researchers to visualize where receptors The Future of GPCR Collaboration in Metabolic Research The next decade of metabolic research won’t hinge

Our access program for researchers in developing countries  continues as well: eligible scientists can They go beyond sponsorship to bring tools and technologies directly to the researchers who use them , Our partnerships with Celtarys Research  and Revvity are great examples — uniting innovation and application to advance GPCR research worldwide. a global platform dedicated to connecting GPCR scientists, industry experts, and innovators through research

From Patient to Researcher Alex wasn’t always planning to be a scientist. changed when his recurring pain — and the rigid protocols around opioid prescription — forced him to search school, Serafini aims to follow the physician-scientist path: part-time clinical work, mostly lab-based research journey proves how personal pain can lead to professional purpose — and why the next generation of pain researchers needs to start from lived experience, not just literature. _________________ Keyword Cloud: GPCR research

GPCR assay that makes it to market carries years of failures, late-night ideas, risky bets, and off-script behind-the-scenes access to GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research

If you’ve felt the pace of GPCR research accelerating—and the signal getting harder to separate from Career opportunities:  In vitro Pharmacology Research Assistant—Geneva. drug hunters, and decision-makers stay grounded in fundamentals while keeping pace with modern GPCR research inputs, members get a coherent view of the GPCR landscape—connecting fundamentals to application, and research Premium Edition here ➤ From the Community “Great initiative—clear guidance on career paths, choosing research

Meanwhile, researchers in the building across the way turned off the lights at 6 PM. Hodson made what seemed like a purely tactical decision: choose a research elective to focus on exams That choice led him to immunology research on pigs — and, eventually, to a PhD. That partnership eventually produced fluorescent GPCR tools  that allow researchers to visualize GPCR differently in different patients These tools have now been shared with hundreds of labs , accelerating research

When Sokhom joined Alkermes, the company had a strong development arm, but a relatively underdeveloped research In a field like GPCR research (where data complexity and failure rates are high), scientific rigor thrives GPCR ecosystem , GPCR research community , GPCR podcast , GPCR data platform , GPCR training program

At a conference booth in 2018, a researcher arrived with a problem that had already cost him months. Ball came to them by way of medicine, an MD, training in internal medicine, then a turn to the research She knew, first-hand, exactly the kind of wasted months the researcher at that booth was describing. Lin insist, are not the vendor but the researchers who run these systems every day.

, This week's breakthroughs are crucial for staying ahead in the rapidly evolving landscape of GPCR research Career opportunities:  Explore a selection of high-level job openings in high-throughput screening, research Catherine’s research, blending GPCR signaling studies with public health data, offers critical insights Competitive Edge:  Stay informed on emerging public health threats and the scientific research aimed Shape the next generation of cellular biochemistry research.

Celtarys Research expands its assay tools with CELT-419 for D3 receptor studies, and Dr. The Kenakin Brief Fluorescent Probe CELT-419 Powers D3R Binding Assays Across Platforms   Celtarys Research Maria Majellaro’s path from lab research to co-founding Celtarys, as told in her recent Dr. Explore this week’s research, tools, and biotech insights in one place.

transmitting signals from the outside into the cells, making them an essential target in biomedical research PerkinElmer High Content Analysis System Operetta CLS used by a Celtarys Research coworker. Exploring the Applications of Confocal Fluorescence Microscopy in GPCR Research In GPCR research one Fluorescence Microscopy validation performed in the ONCOMET laboratory (Health Research Institute of

For most researchers, that’s a dead end. For Alessandro Nicoli, it’s an opportunity. —Alessandro Nicoli For the first time, researchers had a reliable set of predicted structures to work —Alessandro Nicoli A New Era of GPCR Research AlphaFold didn’t just fill a gap—it shifted the focus of

Explore the newest breakthroughs and thrilling research findings in this week's update! McCormick , Cristina Salmerón ,   Paul A Insel PGxDB: an interactive web-platform for pharmacogenomics research Sharing groundbreaking research and industry updates. Jude Children's Research Hospital Welcomes Dr. PGxDB: an interactive web-platform for pharmacogenomics research GPCRdb in 2025: adding odorant receptors

A Career Built on Consistency From CGRP receptor antagonists at BMS to opioid receptor research at Alkermes drug discovery , G protein-coupled receptors , GPCR webinar series , GPCR scientist network , GPCR research

The research team, led by Brandon Novy and colleagues, utilized an innovative APEX2/AUR biosensor that By employing this biosensor, the research team identified 492 genes that significantly influence DOR After the labeling reaction, the researchers purified and biotinylated proteins (those that have been As the opioid crisis continues to challenge public health, insights gained from this research could inform The implications of this research extend beyond basic science ; understanding the role of DNAJC13 in

of Heydenreich et al. (2023) will be analysed to demonstrate how mutagenesis can be employed in GPCR research Through an in-depth mutational analysis of β2AR, the researchers identified specific residues that influence This case study underscores the critical importance of mutagenesis in GPCR research. Rational Drug Design One immediate application of this research lies in rational drug design . By identifying key β2AR residues that influence efficacy and potency, pharmaceutical researchers can

Researchers may also utilize genetically encoded calcium indicators (GECIs), which employ engineered This allows researchers to perform either fluorescent or luminescent calcium measurements depending on Calcium assays are also nondestructive and can be performed in living cells, allowing researchers to Researchers must also account for the fact that calcium serves as a ubiquitous intracellular messenger As researchers balance assay sensitivity, biological relevance, and screening requirements, selecting

. 👉 Most founders don’t even realize they’re still running their company like an academic research group scientific thinking can become a leadership liability and what mindset shifts are needed to evolve from research In research, acting on incomplete or shaky data can destroy your credibility. Startups Play by Different Rules — and Most Scientific Founders Miss That   A research lab is designed Founders who keep operating like researchers often create internal confusion.

The Tools to Detect Them Using the multiplexed GPCR library and Luminex assay , researchers can now: is being bound Determine if the antibody is activating or inhibitory Guide diagnostics or treatment research

environment, paired with a supportive supervisor, laid the foundation for a fulfilling and productive research Supervisors not only guide your research but also shape your academic and professional growth. These mini "journal clubs" kept me informed about the latest research and sharpened my critical thinking choose a lab and mentor that align with your values and goals, embrace the discipline of structured research challenges will test your resolve, but every small victory along the way shapes you into a stronger researcher

His work spans deep academic research, startup life, and the application of machine learning and pharmacology There, Ajay expanded his understanding of neurobiology and translational research models, further refining He emphasizes that building a startup is not simply a continuation of research — it requires a mindset Advice for Young Scientists For early-career researchers, Ajay’s journey offers a powerful blueprint. addiction, or another unmet need, keeping the real-world impact in focus can clarify career decisions and research

The researchers found that certain GPCRs, such as vasopressin receptors, were expressed in hematopoietic The researchers conducted a comparative analysis with previous studies, notably the work by Groot-Kormelink understanding of GPCR expression in human immune cells and platelets, providing a valuable resource for future research As the field continues to evolve, the insights gained from this research will be instrumental in shaping

Check out our latest coverage of GPCRs this week, featuring 15 insightful research papers and industry Stay informed with the latest GPCR research and industry news. Nicola J Smith, Lauren T May, and Natasha L Grimsey for their work on Highlights and hot topics in GPCR research Join the global GPCR community and share your research—submit your abstract using this form. Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Join Dr.