to teach pharmacy and continue GPCR research at an institute for higher education, where his group built GRK2 and GRK3 differ - 10:16 The phosphorylation deficient receptor that desensitized better - 13:00 Building

Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I am a postdoctoral research fellow endeavoring to build

invisible to bench scientists, ranging from medical science liaison and clinical research roles to business

Intended for scientists with a working knowledge of GPCR pharmacology who use, or plan to build, cell-based first author of a 2026 Nature study that used genetic code expansion and bioorthogonal labeling to build

Burning Curiosity as the Non-Negotiable Hay's advice to junior scientists distills to a single criterion Reproducibility, target validation, and the cost of science that cannot be repeated 34:53 Career advice - burning , deep drive still to get over those failures and pick yourself up, and that's a strong enough fire burning

under real experimental constraints, Tried to map signaling heterogeneity in disease-relevant models, Built Her recognitions include the 2024 ASCEPT Achievement Award, the 2023 BPS Geoffrey Burnstock Prize, and Scientific Journey From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Collaboration Built

heterodimerization and the inter-subunit latch to an unexpected discovery of phospholipids inside the transmembrane bundle conformation, leading to an unexpected discovery: phospholipids embedded inside each transmembrane bundle Phospholipids inside the transmembrane bundle: a discovery nobody expected When Fan's team solved the cavity of each TM bundle. of each TM bundle."

After switching to biotech, Murat has built cell imaging software and lab robots to accelerate cancer

to predict signaling bias The entrepreneurial lessons no one tells postdocs: how to pitch, fail, and build He’s a strong advocate for cross-disciplinary thinking, mentoring young scientists, and building companies

That discovery became the foundation of a career built on the data most pharmacologists generate but The Neurocrin team had to confront an explanation no assay had been designed to find — and then built GPCR Theory Was Built to Be Used One of Hoare's recurring arguments is that GPCRs are unusually tractable The practical knowledge of what buffer conditions work, what assay artifacts to expect, what the literature pharmacologists skip 01:45:04 Biased agonism and residence time as tools in the drug discovery toolbox 01:52:09 Building

and a GPCR share a black widow spider toxin binding site — on adhesion GPCRs, synapse formation, and building Boucard Laboratory at the National Autonomous University of Mexico (UNAM) in Mexico City, where he has built Chef's Table Season 2 43:45 Time, focus, and the discipline of 15 minutes a day 52:38 Why Mexico City: building

after insightful experiences in academic, hospital, and industry labs, I decided to pursue a role in business In my role at Orion Biotechnology, I work at the intersection of science and business, which includes target selection, preclinical strategy and business development. Caron has received numerous awards including a Burroughs Wellcome Fund Career Award in the Biomedical Program in Neuroscience, and Life Sciences Summer Undergraduate Research Program and is working to build

quantitative model turned her artifacts into real pharmacological responses, the throughline has never been building Piñeyro's answer is blunt: she does not think of herself as having built a career. I was not building a career. I was simply following my interests." About this episode Dr.

Sokhom Pin shares how he built a biotech career around GPCRs, designed a custom PhD path, and led teams I was trusted to build a team from scratch.” He built what others called the “happiest team at Alkermes,” showing that joy and scientific rigor aren

postdocs considering industry Selected Quotes "Instead of directly targeting the receptor like morphine or buprenorphine

Building Z7 Biotech – The unexpected journey into biotech entrepreneurship, providing GPCR profiling

Brown sitting with a table of actives and inactives — was that the active condition was the acetate buffer set a career in motion 07:07 A venture capital visit to the LMB and the founding of Heptares 11:28 Building ignoring GPCRs 36:39 The GABA-B heterodimer — the moment baclofen finally worked 40:06 The acetate-in-the-buffer

Arthur highlighted his mentors' influence, such as Fred Mitchelson and Nigel Burch, and significant discoveries Arthur shared his career journey, including his collaboration with Patrick Sexton and Jim Burch, and early papers related to the topic, including work by Brian Roth, Terry Kenakin, Bill Clarke, and Kelly Burke

InterAx treats GPCR pharmacology the way engineers treat aircraft design: build the mathematical model Young founders should not build alone.

is not machine learning, and neither is simple computational modeling) to the practical realities of building An MD-PhD who has practiced machine learning since 1989, he built Pharos, the public-facing data platform Buffers, incubation temperatures, time points, co-expression conditions, the specific Emax reference

designing preclinical models of fentanyl and xylazine overdose, she reflects on staying in academia, building What You’ll Learn in This Episode How industry lab experience builds the discipline needed for academic

Activation typically takes 3–10 business days . Need to add members later? Explore : Foundational Lessons — Build Your Pharmacology Core Emerging Drug Hunter — Expand Your Edge

structural biology—and where it still falls short Advice for junior scientists: what really matters when building That moment launched a career built around using computational tools to answer big biological questions Jens is passionate about prediction over explanation: building models that can guide experiments, not

Ilana Kotliar built a multiplexed platform to map GPCR-RAMP interactions and uncover autoantibody-driven She expanded the original Family B focus to encompass the entire GPCR superfamily , building a digital

Johannes Broichhagen shares how his lab builds next-generation fluorescent probes to visualize GPCRs Tried to build assays that behave in living cells—not just on paper.

Aaron Sato on building the synthetic antibody library that finally makes GPCRs tractable — and the greenfield This conversation explores how synthetic antibody phage display libraries, built on silicon-based DNA For Aaron, this work is personal: he has built his career hunting greenfield targets where others had His current focus is building synthetic phage display libraries that drug targets the field has long

And I remember thinking to myself as a young buck at the time: I'm going to show this guy.

led him into GPCR research, drug discovery, and membrane protein biology—plus practical insights on building

For Comeo, who entered GPCR research without any background in the field and built her PhD around chemistry

After a well needed break from the grind, I am now a scientific/business consultant for clients both